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Abstract
Women who do early detection of breast cancer can be said to be still a little. Though the
importance of breast examination since early is to know a woman's breasts under normal
circumstances or not. This study aims to determine the proportion of several specific factors
that cause the risk of breast cancer incidence in women aged 25-65 years with an
observational analytic method with case control design. Sampling is done by using
probability sampling with simple random sampling technique approach. The sample size was
23 women in the case group and 46 women in the control group in the working area of
Gandus and Dempo, South Sumatera – Palembang sub-districts from May to September
2017. Screening data were collected using a questionnaire and analyzed by bivariate analysis
using chi square and fisher's exact statistical tests, continued with multivariate analysis using
multiple logistic regression statistic test. Based on the results of bivariate analysis found that
there are 7 specific risk factors from the overall 15 related factors (p value <0.05) with risk
factors for breast cancer incidence. The seven specific risk factors were age (OR: 0.6, 95%
CI: 0.53-0.79), first menstrual period (OR: 24; 95% CI: 2.76-207.98), history of tumor (OR:
3.2, 95% CI: 2.28-4.75), long breastfeeding (OR : 95% CI: 2.23-4.54), consumption of fatty
foods (OR: 0.2; 95% CI: 0.07-1.00), types of hormonal contraceptives (p value <0 , 05). The
result of multivariate analysis with multiple logistic regression was found that menstrual age
was the specific factor of a person detected at risk of breast cancer (p value 0.05-0.55) is very
important because most women are not aware of breast cancer symptoms and risk factors that
are difficult to handle.
4. Result
The proportion of women at risk of breast cancer incidence was 33.3% of the 69
women aged 25-65 years.
Table.4 Final Model Multiple Logistic Regression Analysis Of Specific Breast Cancer Risk
Factors
Based on the result of multivariate analysis that the first age mestruasi is a specific risk factor
in the last modeling (p value <0.05, Exp (B): 0.05, 95% CI: 0,06-0,55) with multiple logistic
regression statistic.
5. Discussion Menopause
History of Breast Cancer and Ovarian In the Marice study (2014), proving that
Cancer there is a relationship between stress levels
with breast tumors (p value <0.05). The
Breasts are organs on the right and left statement of Walta Gautama (2014) in
sides of the body where the system is Asep Chandra (2014), on Kompas media,
strongly influenced by the same factors that stress can trigger the occurrence of
(Indrati (2005), Scheinn (1997)). Women breast cancer where stress will increase
who have a previous history of breast one's estrogen hormone, so that can trigger
cancer are at risk for developing breast the occurrence of breast cancer. In severe
cancer. Women who have a history of stress conditions can lead to disruption of
ovarian cancer may also be at risk of the body's cellular balance. The state of
developing breast cancer. This is because stress can affect the cell to become
the discovery of the relationship between hyperactive and may experience
breast cancer and ovarian cancer is proliferation so that it can experience a
estimated due to imbalance hormone proliferation that can be at risk of breast
estrogen (Indarati (2005); Dupont (2004); cancer incidence. (KKP, MOH, 2017).
Pherson (2000)).