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  • FTL 3

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    Flt-3 is known as a cell surface receptor for cytokine FLT-3 ligand and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Mutations of Flt-3 that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways. Mutations happened would lead to cancer such as leukemia. Signaling through FLT-3 is important for lymphocyte development.

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    FTL-3

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    Flt-3 is known as a cell surface receptor for cytokine FLT-3 ligand and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Mutations of Flt-3 that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways. Mutations happened would lead to cancer such as leukemia. Signaling through FLT-3 is important for lymphocyte development.

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    4 views1 page

    FTL 3

    Uploaded by

    CreativeBiomart
    Flt-3 is known as a cell surface receptor for cytokine FLT-3 ligand and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Mutations of Flt-3 that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways. Mutations happened would lead to cancer such as leukemia. Signaling through FLT-3 is important for lymphocyte development.

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    © All Rights Reserved
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    of 1

    Flt-3 is known as a cell surface receptor for

    cytokine FLT-3 ligand and regulates differentiation,


    proliferation and survival of hematopoietic
    progenitor cells and of dendritic cells. Mutations of
    Flt-3 that cause constitutive kinase activity promote
    cell proliferation and resistance to apoptosis via the
    activation of multiple signaling pathways. Mutations
    happened would lead to cancer such as leukemia.
    Signaling through FLT-3 is important for lymphocyte
    development.

    Full Name fms-related tyrosine kinase 3 Research area

    Cancer Immunotherapy;
    FLT3; CD135; FLK2; STK1; Immune Checkpoint;
    Synonyms
    STK-1; CD135 antigen; FLK-2. Immunotherapy;
    Targeted Therapy

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