BMS424

Frederick Griffith experiment 1928

The retrieval of live S strain organisms showed that, somehow the heat-killed S strain organisms had
caused the transformation of live R strain organisms to live S strain organisms.

Oswald Avery experiment 1944

By this experiment, process of elimination showed that DNA was the factor that caused genetic
transformation. DNA is the molecule of inheritance.

Hershey-chase experiment 1953

This experiment clearly showed that DNA was transferred from the phage to the bacteria, thus
establishing its place as the fundamental carrier of genetic information.

Tobacco Mosaic Virus experiment 1956

In this experiment, Tobacco Mosaic Virus that only has RNA have the ability to cause infection on
tobacco leaf. It demonstrated that RNA (not protein) is the genetic material of Tobacco Mosaic Virus.

Griffith Avery
-discovered a “transforming principle” that -discovered that DNA is the material of
caused inheritance which genes and chromosomes are made.
-no enzyme - has enzyme protease and DNA