Plastic Surgery Arts

Center

By: Amy Agueros

&
Hadeel Al-Sahli
 Mentorship
Mentor: Dr. Jan Garcia
Location: Plastic Surgery Arts Center
Tasks: Observation of the patients
ISM Teacher: Valerie Kahlich
Evaluators: Mrs. Sylvia Rodriguez &
Ms. Cecily Medina

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 Subject Study
Case of the
Amniotic
Membrane
Functions

Inspiration Inform Knowledge

Inspire others on Inform others on my Learn through

similar research findings such as medical journals and
topics patients articles
Reasons
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 Introduction
Where is it found: Innermost layer of
female placenta during c-section. Single
layer amnion cell fixed to collagen-rich
mesenchyme attached to the chorion
What is it?: Avascular stromal matrix with a
thick basement membrane which promotes
epithelial growth
Characteristics: Anti-inflammatory &
bacterial & viral & angiogenic, and has
immunological characteristics Contos
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 The discovery
Who
Dr. JW Davis: introduced as skin graft
Sabella: Used AM as permanent
coverage for wounds.
Douglas: First to use AM as temporary
biological dressing for wounds (skin
substitution)
When: Early 20th century
Why: Promote patient healthcare
How: Through extensive research Contos
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 Location & Step by
Step Procedure
Location: Skin burns and wounds, chronic
ulcers, and more
Product: AmnioBand Viable Membrane
Procedure: Take out of frozen storage->
Peel outer layer to submerge in saline for
thawing-> Transfer retainer into D5LR->
Separate retainer to pull allograft w/ forceps
Preservation: C-section performed-> Tested
and mixed w/ various solutions for
evaluation Contos
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 Different functions in
Plastic Surgery
General Function: Regenerate tissue
Orthopedic: Safe and non-tumorigenic,
producing an abundance of growth factors that
have shown promise as tissue scaffolds and as
aids in the regeneration of human bone and
soft tissues.
dermatology:Anti-inflammatory and anti
angiogenic properties to facilitate wound
healing.
Study A: Promote healing and reduced scar
formation, prevent tissue of Inflammation and
regenerate tissue
Study B: Longer time to heal wound injury Contos
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 Positive effects of
Amniotic Membrane
Faster results than normal standard care
● 80% vs 20% healing in 12 weeks
● 83% of patients achieved complete
wound healing
● 70% patient’s wound reduced after
first week
● Recovery time: 21 days vs double
(can vary)

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 Future Use and
Advancements

- Underwent different phases of

application
- Hopes of expanding its use and
increasing its portion sizes.

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 Does Age Matter?
Age Matter: No-several months to 65
years
Usual problem: Superficial burns & open
wounds
Trial: 10 kids-24% covered in wounds &
recovery time differed from control
group. 31 days vs. 56 days

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 Conclusion
Challenges/ Overcoming: Finding
sources
Learned: The amniotic membrane
affects in patient health care.
Hopes of achieving: Continuously
advancing patients health.

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Thank You!

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 Citations
Dua, H. S. (1999, June 1). Amniotic Membrane Transplantation. Retrieved November 10, 2019, from https://bjo.bmj.com/content/83/6/748.citation-tools#article-bottom.
ElHeneidy, H., Omran, E., Halwagy, A., Al-Inany, H., Al-Ansary, M., & Gad, A. (2016). Amniotic membrane can be a valid source for wound healing. International journal of
women's health, 8, 225–231. doi:10.2147/IJWH.S96636
Eskandarlou, M., Azimi, M., Rabiee, S., & Seif Rabiee, M. A. (2016). The Healing Effect of Amniotic Membrane in Burn Patients. World journal of plastic surgery, 5(1), 39–44.
GI, A. (n.d.). Amniotic membrane dressing for burns in children. A cheap method of treatment for developing countries. Retrieved November 10, 2019, from
https://europepmc.org/abstract/med/7314235.
In-Office Use of Amniotic Membrane. (2016, April 22). Retrieved November 10, 2019, from https://www.aao.org/eyenet/article/in-office-use-of-amniotic-membrane.
Lumin PDF - Beautiful PDF Editor. (n.d.). Retrieved from
https://www.luminpdf.com/open/google/?state={"ids":["0B5DQOxtWL64KQWdiQk9tbXpxX2w3MF8yN0ZUVFd0VEZZUGVj"],"action":"open","userId":"1072
26491974724325574"}.
Mohan, R., Bajaj, A., & Gundappa, M. (2017). Human Amnion Membrane: Potential Applications in Oral and Periodontal Field. Journal of International Society of Preventive
& Community Dentistry, 7(1), 15–21. doi:10.4103/jispcd.JISPCD_359_16
Orthop, J., Heckmann, N., Auran, R., & Mirzayan, R. (2019, September 19). Application of Amniotic Tissue in Orthopedic Surgery. Retrieved from
https://www.mdedge.com/surgery/article/118167/biologics/application-amniotic-tissue-orthopedic-surgery.
Our Story. (n.d.). Retrieved from https://amnioxmedical.com/our-story/.
Rennie, K., Gruslin, A., Hengstschläger, M., Pei, D., Cai, J., Nikaido, T., & Bani-Yaghoub, M. (2012). Applications of amniotic membrane and fluid in stem cell biology and
regenerative medicine. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474290/.
Toda, A., Okabe, M., Yoshida, T., & Nikaido, T. (2007, November). The potential of amniotic membrane/amnion-derived cells for regeneration of various tissues. Retrieved from
https://www.ncbi.nlm.nih.gov/pubmed/17986813.