Be ene DAI HOC Y DUG TP. HO CHI MINH KHOA Y BO MON MIEN DICH & SINH LY BENH Ho va ten: DE THI MIEN DICH & SINH LY BENH LOP RANG HAM MAT 2013 ( LAN 1) NAM HOC 2045 - 2016 Ngay thi: 18 thang 01 nam 2016 | Huéng dan: © Chon cAu dung nhat: danh chéo cau dung nhat vao phiéu tra loi © Thdi gian lam bai thi: 50 phut © Sinh vién phai dién day du tén, lop, td. Bai thi nao khéng c6 du tén, lép, té sé bi huy bd.1. Nhom phi hop mé & ngwoi A duge goi ld nhom MHC. . B. duge goi la nhom H2 (® duge goi la nhom HLA D. duge goi la nhém DNA E. chinh la nhém mau 2. Chire nang ciia nhom phi hop mé lop | & 1a A. Phong ngiva thai loai mah ghép B. Trinh dién khang nguyén cho té bao B ‘Ge Trinh dién khang nguyén cho té bao T D. Van chuyén khang nguyén dén té bao trinh dién khang nguyén E. XiPly khang ngyén 3. Manh ghép bi thai loai chil yéu la do A. hé théng mién dich cia nguéi nhan chéng lai nhom mau cia ngudi cho. ‘8Q hé théng mién dich cia ngurdi han chéng lai khang nguyén HLA cilia ngwdi cho. C. hé théng mién dich cia ngurdi cho chéng lai nhom mau cia ngudi nhan D. hé théng min dich ctia ngudi cho chéng lai khang nguyén HLA olla nguéi nhan E. b&t twong hop vé gidi tinh gitra ngudi cho va ngudi nhan 4. Yéu t6 quyét dinh manh peptid KN sé duge trinh dién hoac trén phan ter HLA lop | hoc trén phan tir HLA lop Ila ‘A. D6 dai ciia manh peptid KN B. Thanh phan cau tao clia manh peptid KN “Go Con dudng xi ly manh peptid KN trong té bao trinh dién KN D. Trinh ty chudi nucleotid cia manh peptid KN E. Ailyc gitra manh peptid khang nguyén voi phan tir HLA 5. Cac bénh ly sau day la biéu hién cia hién tugng phan vé b6 phan NGOAI TRU’ A. Hen phé quan 8. Cham C, May day . a Séc phan vé E. Viém mai di eng 6. Phan tng qua mn type Il la A. Phan tng qua man tire khac B. Phan ng qua man do phtrc hop mién dich Phan tng déc té bao phy thuéc khang thé D. Phan tng qué man qua trung gian té bao E. Phan tng qua man kich thich 7. Cac yéu té clia bé thé (tt C2 dén C5) khi hoat héa thi bj cat thanh 2 manh a va b, cdc manh b thwéng bam trén té bao dich, ngoai trv A. Cb B. C3b C. Céb FOC E. C5b a | |8. Tht pham gay ra séc phan vé la do A. Tac dung ciia cytokin 38 Tac dung sinh hoc cia hoa chat trung gian C. Tac dung ciia epoetin D. Tut huyét ap E. Réi loan vi tun hoan 9. Co ché gay tén thong trong qué man muén_la do ‘) A. Lympho T va cdc cytokin B. TAc dung sinh hoc cia hoa chat trung giafy C. Khang thé gay déc té bao D. Phive hyp khang nguyén - khang thé 7 "& Té bao mast va bach cau ai kiém 10. Khang thé tham gia vao phan tng qua man type | la A. IgA B. IgM C IgG D. IgD 2. WWE 11, pHimau binh thuéng dao dng trong mot gidi han rt hep tl A. 7,55-7,65 B. 7,45-7,55. JRO7,35 - 7,45. D. 7,25-7,35. E, 7,15 -7,25 12.Yéu t6 gip phan loai nguyén nhan cia nhiém toan chuyén héa la A. Néng d6 duéng huyét B. 86 thdm thdu huyét twong _G. Néng dé ion H+/ mau a $ Khoang tréng anion . E. Ndng dé bicarbonat 13.Yéu t6 khdi phat gay ra nhiém toan hé hap [4 do A. Tang PCO2 B. Gidm PCO, \ C._Tang HCOs" ‘Gidm HCOs E. Gidm PO, 14.Cac cht sau day 6 tinh sinh mién dich manh, NGOAI TRU A. protein 6 thanh phan cau tao 2 ba loai axit amin tro lér B. protein c6 khdi lvgng > 50.000Da~ C. protein ¢6 cdc axit amin vong thom nhu’ tyrosin, phenylalanin thém vao thanh phan cau tao ‘Ps cht khéng bi phan hy bdi qué trinh sinh hoc trong co thé E, chat dé bj bat gitr béi cdc don nhan thyc bao15.Hé lam tang duéng huyét A. Thyroxin B. Glucagon C. Growth Hormone D. Glucocorticoid 28) Ca 4 cau trén déu ding i6.Dau higu nao sau day la dac trung cho nhiém kiém hé hap : A. Gidm thong khi. ri 8, Tang Kali mau. ©, [HCO3+ ] tang. H6i ching tetany E. Gidm Natri/ mau 17.Cac nguyén nhan sau day cé thé gy ra nhiém toan chuyén héa, NGOAI TRU A. Suy than. B. Tiéu dung ©. Tiéu chay. SRONon 61 kéo da, LS Nhiém acid lactic 18. Yéu té nado sau day gitp phan biét phan tir HLA Iép | va lop I? A. Phan tt HLA lp | va lop Il duc ma héa tai nhiing ving khac nhau trén canh ngan cia nhiém s&c thé s6 6 B. Phan tir HLA lgp | dug biéy hién {rén cdc t& bao trinh dién khang nguyén cén I6p Il duge biéu hién trén tat ca té bao S £. Ca hai phan tir HLA durge xép vao dai gia dinh cdc phan tir khéing nguyén bé mat D. Phan tir HLA l6p | dug xem la khang nguyén nhém phi hyp mé chinh cdn lop Il duge xem la khang nguyén nhém phi hop mé phy ~ E. Phan tt HLA l6p | trinh dién khang nguyén cho té bao T CD4 cén lop Il trinh dign khang nguyén cho té bao T CDBG 19.Yéu té lam gidm dwéng huyét A. Thyroxin B. Glucagon C. Growth Hormone D. Glucocorticoid Yk kich thich pho giao cam 20.Dap tng mign dich dac higu déi voi khang nguyén khéng phu thude tuyén We c6 cac dae diém sau,NGOAI TRU A. khéng c6 sy hgp tac gitra lympho T va lympho B B. khéng cé tri nho mi&n dich C. khéng cé sy chuyén Iép khang thé Khang thé tao ra & dap tng mién dich lan 2 voi khang nguyén [a IgG E™ Khang thé tao ra & dap ting mién dich [An 2 voi khang nguyén la IgM. a21.Nguyén nhan, KHONG lam gidm duéng huyét A. Uté bao a dado tuy B. Thiéu hut men gan C. Thiéu hut ACTH 0Qua san thong than | E. Do rvgu 22.Ngan ngiva ha duéng huyét bang cach, chon cau SAI A. Biéu chinh cdc thuéc diéu tri ha dung huyét B. Khuyén bénh nhan n udng ding ba ding gid’ ¢ “HKBiam dy tray dvong D. Diing hormone thay thé E. Biéu chinh hoat déng thé lve 23.Tinh trang dé khang insulin trong tiéu duéng type 2 dan dén ERG loan van chuyén glucose B. Gidm phan giai lipid 7 C. Giam san xudt glucose 6 gan $ Oxgang si? dung glucose & mé co va md mS E. Acid béo tu do trong huyét twong gidm - 24,Phan loai 5 l6p lipoprotein bao gam A. Triglycerides, Phospholipid, Ctiolesterol, Acid béo ty do, Chylomicron Chylomicron, VLDL, IDL, LDL, HDL C. Triglycerides, Phospholipid, Cholesterol, LDL, HDL D. Triglycerides, Phospholipid, Cholesterol toan phan, Cholesterol ester, Chylomicron E. Triglycerides, Phospholipid, Cholesterol toan phan, Cholesterol ester, Acid béo ty do 9 25.Tang tao thanh cac lipoprotein giau t A. VLDL B. Cholesterol toan phan C. HDL D. Lipid mau E. LDL 26.Hap tng mién dich dac hiéu déi voi khang nquyén phuthude tuyén tr c6 cac dac diém sau,NGOAI TRU A. 06 sw hop tac gitva lympho T va lympho B_~ B. 06 tri nh min dich, C. 6 sy chuyén lép khang thé D. Khang thé tao ra & dap teng mién dich lan 2 voi khang nguyén [a IgG J® Khang thé tao ra & dap ting mign dich lin 2 voi khéing nguyén la IgM lyceride lam tang27.Nhiém vu clia Apo B-48 A. Hoat héa LPL B. Uc ché LPL | C. Cau tao HDL POréng hop Chylomicron E. Tang hop VLDL. q 28.Thiéu hut men Hepatic lipase KHONG cé dac diém | J ALDLtang ~ B. La bénh di truyén ~ C. Triglyceride huyét twong tang ,~ holesterol tng . E. HDL giam 29.Bénh do chat khi bi "do ban” la hoc thuyét gidi thich bénh cla nén Y hoc cd A Lama) ————— Da cap C. Hy lap D. Trung hoa | E. Ando * . ! enh la do | 30.Hippocrate dua ra quan niém: C16) loan 4 chat dich” B. 6 may sinh hoc bi hu hdng” C. réiloan can bang ndi méi D. r6i loan cc chat héa hoo” E. tn thurong té bao” 31.Sinh ly bénh hoc ta mén Y hoc A.-hinh thai boo so C. lam sang. D. can lam sang E. dy phong 32.Bénh nguyén hoc nghién ctu vé A. Nguyén nhan sinh ra bénh va mdi tuong quan cila ching | B. Co ché gay nén mét bénh va vong xodn bénh ly cdc co ché AD Nguyén nhan va digu kign thuan Igi gay ra bénh D. Co ché phat sinh, phat trién, tién trién va két thc cla bénh E. Twong tac gitta méi trudng va thé tang cla bénh nhan 33.Claude Bernard dug coi la ngudi khai sinh ra Sinh ly bénh hoc vi da d& ra A. Thuyét vé cé may sinh hoc B. Thuyét can bang ndi méi \Yo Phuong phap thy nghiém trong Y hoc D. Ly thuyét tn thuong té bao ~ E. Nén tang mién dich hoc34.H6 théng bé thé c6 dac diém A. Sé long tang lén trong mién dich thi 2 B. Thudc thanh phan cia mién dich dac hiéu C. Thudc thanh phan ciia mién dich té bao. D. Chi dugc hoat héa khi co su két hop khang nguyén-khang thé ROLE mat binh thueng trong huyét tong & dang khéng hoat déng 35. Thi ty hoat héa bé thé trong con duéng kinh dién la A. C102C3C4....C9 B. C1C3C2C4....C9 C. C1C4C3C2....69 D. C1C3C4C2....C9 1CAC2C3....C9 yp khang thé cé hiéu suat hoat hoa bé thé theo con duéng kinh dién manh nhat la ‘A. IgA = B. IgE | C. IgM . IgD E. IgG 37.Trong con dung tat, thanh phan tong dong véi C4b2a3b cia con duéng lectin Ia A.C3 B. C3b C. C3bB D. C3bBb Qe C3bBb3b 38.0’ té bao trinh dién khang nguyén, khang nguyén ngoai sinh duoc xt ly tai tdi A. Phagosome B. Proteasome Lysosome (Crhogayosome E. Phagoproteasome 39.Khang nguyén ngoai sinh dug Té bao trinh dién khang nguyén trinh dién cho Lympho A. Ts 8. Te on Teg :. T killer 40. Cac t8 bao trinh dién khdrig nguyén trinh dién khang nguyén ngoai sinh trén phan ti phu hop mé lop ch I (oh DWV EV a41.Co quan lymphé ngoai vi la: A. Tuy xuong 8. Hach bach huyét C. Thymus D. Ving duréi adi E. Tui Fabricius 42.Trong dap tng mién dich thi 1, khang thé sinh ra chi yéu thudc lop A IgA 8. IgD C. IgE D. IgG E. IgM 43. So v6i dap teng mi&n dich thi 1, pha tiém dn & dp tng mién dich thi 2 c6 thoi gian A. Daihon B. Ngan hon C. Bang nhau O. Thay déi E. Tuy vao ban chat khang nguyén 44.Co ché phat sét c6 cac dac diém sau, NGOAI TRU: A. PGE, tryc tiép gy tang diém diéu nhiét B. cAMP tryc tiép gay tang diém diéu nhiét C. Réi loan trung tam diéu nhiét D. Tang sn nhiét, gdm thai nhiét E. Chat gay sét ndi sinh tham gia gay sét 45.RGi loan chtrc nang va chuyén héa xay ra khi phat sét la: A. Tang nhip tim B. Gidm théng khi C. Gidm thoai héa protein tl co D. Tang dy trav glycogen E. Gidm nhu cu st dung vitamin 46.Trung tam diéu nhiét bi réi loan trong truéng hop: A. Giam than nhiét B. Tang than nhiét C. Nhiém néng D. Sét E. Ha than nhiét nhan tao 47.Chat gay sét ndi sinh cé dac diém sinh hoc sau: A. Uc ché min dich té bao B. Ue ché mién dich dich thé Uc ché bé thé Lam tang CRP (C reactive protein) Tang hap thu Fe moo9 eS 48.Cn chi dinh sém thuéc ha sét & déi tong: A. Nguoi gia B. So sinh C. Nht nhi D. Thanh nién E. Phy nt mang thai 49.Quan niém sau day vé phan ng viém KHONG DUNG: A. Viém Ia phan dng toan than B. Viém cé hai trong mét sé truong hep C. Viém thuéc vé thanh phan mién dich dac hiéu D. Viém 1a mét phan Wng cé Igi nham loai trie yéu té gay bénh, stra chira tin thong E. Viém chiu téc déng cia hé than kinh va hé ngi tiét 50.Vai tré clia hé théng bé thé trong phan trng viém 1a: A. Giup stra chiva va lam lanh vét thuong B. Khu tris tac nan gay viém C. Ly giai vi khuadn D. Uc ché sy di chuyén cia bach cau E. Uc ché hién tugng thu bao 51.Hign twong co tiéu déng mach trong réi loan van mach tai 6 viém do yéu td: in xa than kinh : B. Histamin C. C3a, C5a D. Bradykinin E. LT va PG 52.Djch viém cé cac tinh chat sau, NGOAI TRU: 9 A. La dich tiét S8/La dich thém C. Chita nhiéu protein os D. Rivatta (+) - E. Chiza nhiéu bach cau va dai thyc bao 53.Hién tuong thyc bao téi wu trong diéu kién A. Than nhiét binh thong B. Dich 6 viém toan héa C. Di tugng thy bao dugc opsonin hoa D. Béi tung thyrc bao c6 kich thuée nhé. E. Uc ché héa hung dong 54.T6 bao lymphé T cé cac dac diém sau, NGOAI TRU: A. T.CD4 trinh dign khang nguyén trén HLA lp 2 B. Duge biét hoa & Thymus C. COTCR D. Co dau 4n CD4 hay CD8- E. Biét hoa manh nht & giai doan day thi10 S 55.Té bao cé thu thé voi Fe clia IgE la A. Lympho T B. Lympho B C. Té bao bach tude YO Té bao mast E. Té bao ai toan 56.Thy thé khang nguyén cia té bao lympho B la: A. HLALI B. EBV-R QO FcR D. s-IgM s-gD Igap E. Ti+CD3 57.Khang thé t6ng hop trong giai doan nhiém cap thudc lop: A. IgG B. IgA | C. IgM D. IgD E. IgE | 58.78 bao khéng thuge nhém trinh dién khang nguyén [a A. Té bao bach tugc B. Té bao xde ngén tay C. Té bao lymphé B | D. Té bao lymphé T E. Té bao Kuffer 59.Mt phan tt 6 tinh dc higu khang nguyén va tinh sinh min dich goi la A. khang nguyén hoan chinh B. hapten C. chat tai... = D. taduoc * : E. tolerogen | 60.M6t phan tt chi c6 tinh dc higu khang nguyén nhung khéng cé tinh sinh min dich goi I A. khang nguyén hoan chinh D. taduge E. tolerogen 61.76 bao cla. MOKDULtham gia vao hién tugng thye bao la A. Bai thyc bao va té bao mast 8. Dai thy bao va tuong bao C._ Bach cau hat trung tinh va tong bao 0) Bai thy bao va bach cau hat trung tinh E. lympho T va té bao mastii 2 62.Té bao tham gia vao co ché diét giun tron la A. Lympho T B. Lympho B C. Té bao bach tuéc D. Té bao mast | “E> Té bao di toan 33.0’ bénh nhan bj viém rudt thiva cp, té bao tang lén trong mau cla bénh nhan la re Bach cau hat trung tinh Té bao Ai kiém C. Té bao bach tuéc D. Té bao mast E. Té bao ai toan 64.Té bao lympho dugc biét héa & tuyén trc la A. Lympho T Lympho B . Té bao bach tude |. Té bao mast . Té bao ai toan 65.Khac biét vé isotip cla khang thé la do. A. Céu tric ctia chudi nang khac nhau B. Cu tric cia chudi nhe khac nhau C. Cau tric cia ving ban 1é khac nhau D. CAu tric cia cdc domen hang dinh khac nhau E. Céu tric cia céc domen thay déi khac nhau | | | | | ' 66.Phan quyét dinh cdc thuéc tinh sinh hoc cia phan tle khang thé [a Fab B. F(ab’)2 C. Fe 7 D. Ca Fab va Fe ‘Le E. FoR | 67.Chivc nang clia cdu ti tiét (manh S ) trong phan ti IgA tiét a A. Tang tac dung lién két gidra khang thé va khang nguyén B. Tang sv van chuyén IgA trong huyét trong C. Bao vé IgA khéi bi hy béi cac enzyme tiéu dam trong dich tit D. Gidm téc 6 thoai bién IgA E. Tang tinh bén vieng ciia IgA trong huyét tong ruét la A. IgA B. IgM I a. D. IgD | IgE | a | i i 6p khang thé chiu trach nhiém chinh trong viéc tre ché (trung héa) vi tring & bé mat niém mac |4 i 12 = 9G co cac thudc tinh sinh hoc sau day, ngoai trv: ‘A. Di chuyén qua nhau thi B. Hoat hda bé thé theo con duéng od dién 7 C. Hoat héa bé thé theo con duréng tat a) Cé dinh trén té bao mast va basophil nha thu thé voi khang thé trén té bao nay E. Tham gia phan tng doc té bao phy thudc khang thé po B100, apo R100. 7 phena thé tao ra & dap tng mién dich lan-2 vei khang nguyén [a IgMBat thud: chon cau SAI A. Bénh di truyén 4 B, Hau qua la ai lye gira LDL va LDL receptor bi giam a holesterol huyét tong gidm_ D. LDL huyét tuong tang ~~ E. Phan tl? apo B100 bi bién dj 6 acid amin thr 3509, 71.Thanh phan dién gidi trong céc khu vc A. Cac khu vyre c6 thanh phan dién gidi giéng nhau B. 98% ion Kall cb & ngoai bao C. 90% ion Natri cb & ndi bao DBoTéng sé cation va anion méi khu vue bang nhau E. Téng sé cation va anion méi khu vuc khac nhau uyén nhain gay phit /. Gidm ap suat thiy ti B. Tang ap suat keo. ©. Tang ap suat tharh thauy~ 0. Gin mach bach huyét E. Gidm tinh thdm thanh coo 73.Két qua can lam sang nao sau day huéng chan goan la gidm Natri huyét gid tao A. Gidm dvéng huyét B. Gidm protein huyét C. Gidm nit huyét D. Gidm litpid mau E. Truyén manitot 74.Nguyén nhan va co’ ché bénh sinh clia tang Kali huyét tvong, ngoai trir A. Gidm 46 loc cau than B. Tang tiét Kali tai 6ng than C. Nhiém toan chuyén hoa D. Dich chuyén Kali tr ngi bao ra ngoai bao E. Loi tiéu gid» Kali a13 (i nguéi nam 33 tudi, cn nang 70 kg, thi A. Co khoang 35 lit nude, trong dé:ndi bao chiém 12 lit nvéc, ngoai bao chiém 23 lit nudc B. Cé khoang 49 lit nue, trong dé ngi bao chiém 32 lit nvéc, ngoai bao chiém 17 lit nuée C. C6 khoang 42 lit nude, trong dé néi bao chiém 28 lit nvé>, ngoai bao chiém 14 lit nude D. Cé khoding 36 lit nuéc, trong dé ndi bao chiém 24 lit née, ngoai bao chiém 12 lit nude E, TAt ca cac cau trén déu sai 76.CAn bang protid ‘A. Cén goi la cn bang Nitrit 20 B. Phai do lién tuc trong 1 thang cn C. Cén bang duong tinh thuong gap & phy no cé thai D. Can bang 4m tinh thuéng gap & tr em dang phat trién E. Tat ca déu sai 77.Trong operon, gen kiém soat gen tac déng la A. Gen cu tric B. Gen diéu hoa C. Gen khdi déng D. Gen gidi ma E, Chat kém ham 78.Réi loan gen diéu hoa A. Do héa chat B. Do tia xa C. Do dt bién gen D. Do chusi y khéng bi tre ché E. Gay ra bénh thiéu mau héng cau hinh liém 79.Hb bat thuréng trong bénh Thalassemia Ia do os ‘A. Gen chu6i alpha khéng bi tre ché ° B. Gen chu6i beta khéng bj te ché C. Gen chudi gamma khéng bi tre ché D. Gen chudi delta khéng bj tre ché E. Tat cd déu ding 80.Bénh thiéu mau héng cau hinh liém A. Khi dién di, HbS vé cue dong . Khi dién di, HbS v8 cyrc am . Khi dién di, HbA vé cuc am Xay ra d6t bién thay nucleotid trén chudi a. Chudi B binh thudng mooDAI HQC Y DUOC TP. HO CHi MINH KHOAY — Arn BO MON.MIEN DICH & SINH LY BENH Ho va tén: Nau Way Kang Te 4 Lop: Yor 42. DE THI MIEN DICH & SINH LY BENH LOP Y3 CHINH QUY NAM HOC 2044 - 2015 i Ngay thi: 14 thang 7 nam 2018 a 3 \ t < Hwéng dan: ; © Chon céu ding nat: danh chéo cau dung nhat vao phiéu tra Idi ‘ © Thyc hanh lam bai viét 7 © Théi gian lam bai thi: 55 phit @ Sinh vién phai dién day dii tén, lop, td. Bai thi nao khéng cé dil tén, Iép, t8 sé bj huy bé. a2 Hippocrate, dug t6n vinh la 6ng té cilia yhoc —_—+hién dai, da d8 ra hoc thuyét vé A. 2 ye: am, duong 4 chat dich: trang, dé, vang, den. . 4nguyén té: Iva, khi, dt, nude. D. 5 yéu té: kim, méc, thuy, héa, thd E. Tat ca cau trén déu sai 2 Quan niém ctia Claude Bernard, ngudi dat nén méng cho Sinh ly bénh hoc, ‘A. Bénh Ia do 16i loan 4 chat dich B. Bénh la do od may sinh hoc bj hu héng Bénh [a do réi loan can bang néi moi D. Bénh [a do réiloan cae chat héa hoc E. Bénh la do tn thuong té bao (Site cho rang bénh chila sdn phdm cila su ri loan tiém thie, ® linn hon C. ngi mdi D. co hoc E. t&bao 7 Co ché bénh sinh la cach thtrc van dong cia sy dign tién bénh qua cdc giai doan: Phat sinh, phat trién, tién trién va Véng xoan bénh ly @) két thuc cua bénh C. bénh nguyén cla bénh D. bién ching cua bénh E. hdi phyc bénh iy C3 convertase trong truxdng hop host tac bé thé trong cA 3 con dubng, sé trd thanh CS: convertase khi két hgp thém thanh phan A. Ctb . E. Cb Thanh phan trong dizong voi C'1q alla dong kinh didn khi hoat tac bé thé theo dzong dt la A. Cib 8. C2b @eap D. Cab E. C5b 7. © Bai thc: bao, khang nguyén ngoai sinh bi thyc bao va dua vao bao tworig trong tai A. Phagosome B. Proteasome C. Lysosome Phaigolysosome E. Phagoproteasomiz |5 3 = 8. Cac yéu Cn trong truéng hyp hoat tac b& thé ~—theo con duéng kinh dién va con dung lectir joan ton giéng nhau ngoai tn? n= G ; C. 0. E. 2 x 4 5 9. Lympho B [a thanh phan clia mién dich dac hiéu, nhung cytokin do lympho Th tiét ra dé hoat lympho B cé tinh chat Chon loc Dac higu C. Kh6ng d8¢ hiéu D. Trinhe E, Ngu nhién 10.Trong viém gan B cp (dap teng mién dich nguyén thy), khang thé HBcAb duge sinh ra thuéc lop A. IgA B. IgD G 'g= D. IgG E. IgM 11.Trong Viém gan B man (dap tng min dich thi 2), HBcAb chil yéu thudc lop A. IgA B. IgD C. IgE © sc * E. IgM SGetion trang hady@ng mau & bénh nhan xo gan do cac co’ ché sau day, ngoaitrir \ Gidm dap tng véi glucagon ‘ Ores Insulin thir phat Gidm qué trinh tn tao glucose tai té bao gan*—~ D. Gidm dy tro glycogen tai té bao gan ~~ E. Gia tang sé thu thé va phan sau thy thé Insulin trén té bao gaa. | "B88 xo’ gan, Albumin trong huyét tyeng bi giam do cdc co ché sau day ngoai try Bénh nhan &n It proten B. Gidm téng hgp Albumin tai gan —— | C. Albumin bj thoat vao dich cé treéng-— | D. Chire nang than bj suy lam albumin thay ra nuéc tigu— E. Gidm sé lugng té bao gan_— | 14.Vang da trong tc mat ngoai gan do réi loan qua trinh A. Thu nhén bilirubin B. Lién hop bilirubin ©) tiét bilirubin AvaB E. Bvac 4| — 45.Khi cdc thanh phan bé thé tly C2 dén C5 bi cAt ra lam 2 manh a va b, cc manh b thong, bam lén khang nguyén trong phivc hop khang nguyén-khang thé, gitip cho cdc té bao thyrc bao pat git dé hon, do la tac dung (A) opsonin héa ao anaptiylactoxin C. .ly giai té bao dich . ha huéng déng bach cau E. mién dich két dinh J6.Gia thuyét vé co’ ché sinh bénh ota hén mé gan dao NHS 1a gid thuyét ve A. Chat doc. - B. Chat dan truyén than kinh gid C. Mat cn bang trong chat dan truyén kich thich/ire ché Réi loan chuy€n hod (es loan ngi méi 17.Phan Fe thye hién chtrc nang: A. Thue bao () Quyét dinh thuéc tinh sinh hoc clia khang thé © Quyét dinh tinh dac higu khang nguyén cla khang thé D. Quyét dinh ai lye cla khang thé E. Thoi gian ban hy ca khang thé 18.lgG 06 cdc d&c diém sau day, NGOAI TRU: Xudt hign sém trong dap tng mign dich ky du B. Trung hda doc té vi tring — C. Cé thé hoat héa bé tha — D. Bi qua nhau thai — E. Thdi gian ban hdy tir 21 4én 23 ngay — 19.Dac diém clia lA trong dich tiét la: A. Kh6ng 06 chudi J Kh6ng cé manh tiét_Y © dang dimer_— D. Kich hoat bé thé bang duéng kinh dién E. Biqua nhau thai 20.Bac diém cla IgE la: C6 nhiéu & nuée bot Gén vao cac thu thé trén té bao mast — €. Gén vao thy thé trén dai thyc bao D.. Hoat héa bé thé theo dudng fat E. O dang dimer 21.Cac chat sau day la khang nguyén, NGOAL TRU: Polypeptid Amiang €. Dai phan ti protein D. Albumin E. Polysaccharide5 2 flop khang nguyén nh4n dién boité bao B (khang thé): é Cé dang céu hinh va dang chudi_> 8 c. o. E. Chi 66 dangchudi.5~ 2 phan cuén vao trong.cia phan tS” Chi cé dang cdu Anns. Khéng cé tinh dac hiéu 5° 23.Khang nguyén dui day co dap ting mign dich khong c6 tri nhomién dich: Khang nguyén nhém mau Polysaccharide Khang nguyén ghép D. Khang ngllyén cé edu true protein, E. Cac chat tai 24. Ta dug mién dich la: Chat khi cho vao vezi hapten [am hapten tang tinh gay min dich. Chat lam tng tinh gay mién dich ctia mét khang-nguyén €. Chat khi dua vao lam giam déc tinh olla chat gay min dich. D. Chat opsonin hoa E. Chat tai hapten 25.Yéu té dich thé trong min dich dac hiéu la A. Interferon Khéng thé Acid béo trong tuyén ba D. LysozymeS E. BO that 26.Cac yéu t6 dich thé trong min dich KHONG dc higu gém cac thanh phan sau,NGOA! TRU! A. Interferon —~ 5 8. Protein C phan ung — . Cac acid béo trong tuyén ba x , Lysozym_— - E. Bé thé— 27.16 Bao thudc mi&n dich dac higu la A_Té bao NK (8))céc té bao lympho T Bach cau trung tinh i D. Bach c&u don nhan \ E. Té bao giét ty nhién . 28 Migs dich Gac hiéu 6 cdc dae diém sau,NGOAI TRU: con hién & giai doan don bao S B. Thanh plian dich thé la khang thé —— C. Thanh phan té bao'la lymphocyte D. Bap &ng thi 2 nhanh hon, manh hon, higu qué hoa— E. Dap tng can 06 thei gian_— 2,6 29. Thudc khang vim khéng steroid gay loét da day ta trang do cdc co ché sau day_ngoai tri: A. Ute ché men COX, lam gidm qua trinh tang hop Prostagtandin e da day Gay 6c tryc tiép qua co ché bay ion oa ‘é’ché men COX, lam giém qua trinh téng hop cc chat bao vé niém mac da day Dy Anh hwéng Ién néi mac mach mau gay @ tré tudn hoan lam thiéu mau cuc bd & da day. E. Tén thwong truc tiép chat nhay 30. Bénh nhan bj tiéu chay dg enterotoxin cia vi triing V.cholera gay.ra_ A. Mat nvéc wu truong Mat nuéc’dang trong C. Mat nuéc nhuge trong D. Mat nue hén hep E. Chi mat nude, khéng mat dién gidi. 31. Co ché hap thu natri khéng bi anh hung khi bénh nhan bi tiéu chay tiét dich 1a - A. Hap thu Natri tao dién thé Hap thy Natri trung tinh Hap thy Natri di kém vi Glucose D. Hap thu Natri thy dong Hap thy Natri di kém voi kali 32. Tac rudt gay ra cdc réi loan sinh ly sau , NGOAI TRU’ Chwéng hoi & phia trén chd tic_— Or dich & phia dui ché téc_—— C. Vi tring dueng rudt phat tri&n qua mt D. Gidm nhu déng & phia dudi ché tics E. Thing rudt néu co kém tac nghén mach mau-— phia trén chd téc 33.Lipid duroc phn bé trong co thé & té bao va huyét twong.c6 dac dim _ A. Lipid trorig huyét tong Ivu thong dui dang ty do 1S Lipid dy tro trong té bao dui dang lipoprotein S ep dy tr duerc dy trir trong cac té bao ma D. Acid béo dugc thuy phan tir mé mo E. Triglyceride, phospholipid, cholesterol gan két voi «albumin 34.TY Ig phan tram cdc thanh phan lipid trong Ghylomicron %*TG : %Chol : %PI 95% : 3% Ome Chol : MPL = 95% : 2% : 3% <%TG : %Chol : %PL = 25% : 50% : 25% D. %TG : %Chol : E. %TG : %Chol : 133% * TG: Triglyceride Chol: Cholesterol. Pt: Phospholipid 36.Thanh phan chii yéu.gay xo viva dong mach dian dén cao huyét ap A. Chylomicron aan B. VLDL (OL Ow £. HDL '5 7 = 36,Chylomicron tan du duge gan nhan diéri va bat gi nho Apo E B. Apo B100 ees C. ApéBas D, Apo A-Il E. Apo C-llh 37. Suy hé hdp.dé 2, phan loai theo lm sang ‘A. Khé thé khi hoai dng nhe 8. Kho thé khi hoai déng nang ho thé khi nghi ngoi ho thé it khi hoat déng binh thuéng E. Khé thé it khi hoat dong nhe 38.Qua trinh hé hap dug’ chia lam 4 giai doan A. Théng khi, khuyéch tan, hé hdp trong, hé h4p ngoai B. Cl déng hé hap, khuyéch tan, van chuyén, trao di khi H6 hap ngoai, khuyéch tan, van chuyén, trao di Khi Onassis khuyéch tan, van_chuyén, trao déiket- = Théng khi, van chuyén, khuyéch tan, trao di khi 39,Hen phé quan la bénh ly gay Co )R6i loan giai doan thang khi B. Réi loan giai doan khuyéch tan C. Réiloan giai doan trao d8i Khi D. Réiloan hé hép trong E, Réi loan do nguyén ngan mang khuyéch tan 40.Uf¢ éhé trung tam hd hap do ngé 66c thuée nad gay ra Ci loan giai doan théng khi do gidm co’ hoc hé hap B._ Réi loan giai doan khuéch tan do ri loan dign tich khuéch tan C. Réi loan giai doan k,huéch tan do réi loan mang khuéch tén. 0. Réi loan giai doan Ichuéch tan do rdi loan higu sé khuéch tan E. Réiloan than kinh trung vong 41.Cac yéu té cn bang duéng huyét: A. Glucid thire an, ‘glycogen gan, glucose tan tao. 8. Gan, than kinh, ndi tiét Insulin, glucagon iguén cung cp, ngudn tiéu thy, hé théng diéu hoa dudng huyét E.. Nguén cung c:Ap, ngudn tiéu thu ) 42, Phan loai bénh tidy duong: A. Tiéu dung type 1, tigu dong type 2 va cdc loai tiéu duéng khac Tiéu dong thai ky, tigu dudng khéng trong thai ky i dudng type 1, tidu dung type 2, tigu duéng thai ky va cac loai tiéu dung khac Réi loan dung nap glucose, tigu dudng type 1, tiéu dudng type 2 d8 43.R6i loan chuyén héa glucid trong tigu dong = type Z A. Gidm san xuat glucose & gan va gidm tiéu thy glucose & gan, co, me B. Gidm san xuat glucose & gan va tang tiéu thy glucose & gan, co, mo ‘Tang sén xudt glucose & gan va gidm tiéu thu glucose 6 gan, co, mo D. Tang san xuat glucose & gan va tang tiéu thy glucose & gan, co, me E. San xuat glucose & gan va tiéu thu glucose & gan, co, m& khéng ddi 44.Trigu chteng bénh tiéu dugng dién hinh nhu-dnobidu, tigu_ohidu, udng nude nhiéu con od dau higu A. Vier than (8) Gay ém, syt can Sét 5 D. Lén can, béo phi E. Nhin me 45.Ch8t gy_s6t ndi sinh cé naudén géc chinh te: oo thye bao B. Té bao mast C. Bach cAu trung tinh D. Bach cau i toan E, Bach cau ai kim 46.Yéu té tryc tiép gay tng diém diéy nhigt set point) la: Vikhudn gay bénh cAMP C. PGE2 D. Chat gay sét ndi sinh E. Cyclo Oxygenase 47.Tac nhan_gay sét hang daula- A. Bénh ty mién B. Bénh actinh Nhiém ky sinh tring Gen khuan E. Thuéc giy sét 48. Than nhiét c6 thé giam trong cac trwéng hop sau, NGOAI TRU: A. R6i loan chuyén héa nang lung tram trong (xo gan, tigu dudng, ee Phan xa diéu nhiét mat tac dung khi than nhiét giam qua thap — @) Réi loan trung tam digu nhiét khi tiép xtic voi mdi trvéng cé nhiét do th4p —— ). ‘da than nhiét nhan tao sau khi tc ché phan xa diéu nhiét _ — E. Tiép xUc voi méi truvdng lanh kéo dai du phan xa didu nhiét binh thong — 49,Cbitiéu sau day tagg cao trong méiu chi diém tinh trang viém cdp. RP B. Hdng cau C. Tiéu cau D. IgE E. IgG &9 50,Maj tré cla hé théng bé thé trong phan tng viém la: (a Ly giai vi khuan 8. Khu tru tac nhan gay viém ‘ C. Uc ctié hign tugng thuc bao D. Ue ché su di chuyén cila bach cdu . Gilp siva chtva va lam lanh vét thuong 51.Co’ché chinh clia hién tong hinh thanh dich viém la: A. Tang ap suat thiy tinh B. Gidm ap sudt keo C. Tae mach bach huyét . Tang do nhot'mau Tang tinh thdm thanh mach 2.Cac chat sau day co thé gay sung huyét tai 6 viém, NGOAI TRU: A. Histamin B. ‘Prostaglandin’ — Leucotrien— Arachidonic acid E. Bradykinin 53.16 bao lymphé T c6 cdc dac diém sau, NGOAI TRU: BT CDé trinh dién khang nguygp trén HLA lop 2 — & Duge biét hod 6 tdy xvong CéTCR — D. Cé dau 4n CD4 hay CD8—— E, Biét héa manh nhét 6 giai doan bao thai. —— 54,76 bad lymphé B c6 dc diém sau A. O nguairéuce biét hég 6 tci Fabricius 5 8. Cé phan tir HLA lop 44rén be mat S~ Epstein- Barr virus khéng ‘thé gan lén té bao D> Cé thy thé voi Fe (FoR) tren bs mat E. Cé giai doan biét héa 6 tuyén te rt quan trong S 55.76 bao khéng thudc nhém tinh dién khang nguyén a: A. Té bao bach tuéc_— B. Té bao xde ngén tay-—— Té bao lymphé B T& bao lymphé T Té bao Kuffer A. Cotri nh 8. Nhan dién dc hiéu khang nguyén Nhan din da dang cc khang nguyén DXi ly va trinh dién khang nguyén E. C6 khé, nang thyc bao ac tinh sau gidp £6 bao tinh dién khang nquyén lién quan chat ché voi mién h Bac hiéu i10 57. Thiéu mau huyét tan c6 cac dac diém sau, NGOAI TRU A, St huyét thanh tang B. Héng cau ludi ting — Thé tich mau binh thudng— Bilirubin ty do giam E. Hau hét la thigu mau dang sac, dang bao 58.Bénh Thalassemie la bénh thiéu mau huyét tan c6 cdc dac diém sau, NGOAI TRU: Cé sy hién dién ctia hong cau bia ®rtns cau dang sdc ding bao C. Mic d6 tram trong tuy déng hop ti hay dj hop t#— D. Cé HDF trén dién di hemoglobin. — E. Cé thé gap & ngudi trudng thanh_— 9. Thiéu mau do mat mau cap xay ra trong: ay ut muyet BT RES Hang Bénh Thalassemia . Bénh thigu men G6PD . _Bénh thiéu mau thiéu sat Thiéu mau do nhiém giun méc moo 60.Mat mau cp tinh c6 cdc d&c diém sau, NGOAI TRU: ‘A. C6 kha nang bi triv khi mat dur6i 10% thé tich tuan hoan ——~ B. Mat c& héng cau va huyét tvong-—— C. Thiéu mau dang sdc, dng bao — D. Can bi mau toan phan — (©)vang da nang 61. pH/mau binh thuréng dao d6ng trong mot gid han rét hep tir A. 7,55-7,65 7,45 -7,55. 7,35 — 7,45. 7,25 -7,35. E. 7,15-7,25 62.Yéu t6 gitp phan loai nguyén nhan ca phiém toan chuyéghéa la A. Nong 46 duéng huyét B. D6 thdm th4u huyét tvong Nong 46 ion H+/ mau 6 Khodng trng anion Ndng dé bicarbonat 63,Cac co ché sau day sé dan dén nhigi én hoa NGOAI TRY A. Mat dy tri kidm (tiéu chay...) B. Tang san xuat acid khéng bay hoi (nhiém toan thé ketone...) —~ C. Than gidm thai triv acid (suy thn... Tang théng khi ?hdi hop cdc co ché A va B hodc B va Cit oe 64.D4u hiéu nao sau G4y la dac trung cho nhiém kiém hé hap ‘A. Gidm théng khi. B. Tang Kali/ mau [ HC03+ ] tang. oO H4i chung tetany Giam Natri / mau Suy than man la tinh trang gidm chire nang than A. Trong khoaing 3 thang 8. Trong khoang 3 tuan C. It nhat la tix 3 - 6 thang Nhidu nhdfla ter. 3 - 6 thang @ Tw 6 thang tré len 66.¥u té gitip chung ta danh gia chinh xéc nhdt chive nang than ia Hé sé thanh thai creatinine. B. Hé s6 thanh thai urea. C. Néng 46 creatinine/ mau. D. Thé tich nude tiéu/ 24h E, Nong d6 uré/ mau, 67.Thé tich nuréc tigu trong ngay phy thudc vao nhiéu yéu td. Trong trréng hep tut huyét ap (thi du: xudt huyét), thé tich nuéc tidu gidm :A do A. Ong gop tré nén khéng thdm déi véi nude B. Gidm tai hép thu & éng than C. Truic renin-angiotensin bj tre ché Gciam lwong mau dén than va giém 46 thanh loc cau than eieeee nhan guy thap, lidu legng thud str dung trén lam sng sé éuge diéu chinh theo Néng 46 creatinine mau 8. Nong d6 urea mau Hé sé thanh thai creatinine D. Hé sé thanh thai urea E. pH mau 68.Cac dac trung sau day [a cia gen HLA, NGOAI TRU A. Co biéu hién déng tro 8. Cé tinh da hinh (polymorphism) G. Cé nhiéu gen ma héa cho phan ti? nhém phu hop m6 — Nam trén nhiém sc thé 15 E, Cé nhidu allele trén cng mét locus— 70. Nhém phi hep mé & ngudi A, duge goi la nhom MHC 8. duge goi a nhom H2 durge goi la nhém HLA dug goi la nhérn DNA E. chinh la nhém mau b |12 71, Manh ghép bj thai loai cht yéu la do. hé théng mién dich cla nguéi nhan chéng lai nhom mau cia ngurdi cho. hé théng min dich cla nui nhan chéng lai khang nguyén HLA cla nguoi cho: . hé théngmign dich cla ngudi cho chéng Iai nhém méu olla nguvei nhan D. .hé théng min dich cia ngudi cho chéng lai khang nguyén HLA ctia nguéi nhan E. bat tvong hop vé gidi tinh gitra ngudi cho va ngudi nhan 72. Thudc quan trong nhat trong didu tri phan ve cAp.tinh a: A. Antihistamine B. Corticoid. : - C. Khang sinh. Thudc dan phé quan. Adrenaline. Dap tng mi&n dich d6i voi ph4n hoa thuréng lién quan dén: Réi loan co’ ché dung nap mién dich. Phan tng qué man cém. Phan teng chéng lai nhém phi hep. md. D. Tinh trang nhi&m phén hoa man tinh. £. Bénh ly ty mién. 74,Gaxché gay thn thong trong qué mn mu6n la do A. )Lympho T va cae cytokin B. Tac dung sinh hoc ca héa chat trung gian C. Khang thé gay déc té bao D. Phir hop khang nguyén - khang thé £. Té bao mast va bach cu ai kiém 75.Bénh hyyétthanh 1a do A. Phan tng qua mén tire khdc B. Phan tong déc té bao phu thudc khang thé Phan tng qué man do phi?c hyp mién dich Ivu hanh 0. Phan wng qué man qua trung gian té bao E, Phan tng qué m&n mudn 76.Thanh phan dién gidi trong cdc khu vce A. Cac khu Vue cé thanh phan dién gidi giéng nhau B. 98% ion Kali co & ngoai bao C. 90% ion Natri c6 & néi bao ‘éng s6 catior: va anion mi khu ve bang nhau Téng 86 cation va anion m6i khu vye khac nhau 7T.Nguyén nhan gay phi A Siam ap Arie tinh ‘Tang Gp sudit keo our 4p sudt thém thdu D. Gian macta bach huyét E. Giam tinh tham thanh mach &13 a 78.Sy lién két gira mét bénh voi mot allele HLA dac biét ndo 46 cé nghia la C4 thé.ndo mang allele d6 $6 bi m&c. bénh GA thé nao mang allele d6 cé nguy co mac bénh cao hon C. Phan tl HLA dugc ma héa bi allele a6 bi khiém khuyét D. Allele dé sé dan dan bj mat di E. Ca thé nao mang allele d6 sé khng bi mac bénh 79.Két qué cn lam sang no sau day huéng chan doén la gidm Natri huyét gid tao A. Gidm duéng huyét 8. Gidm protein huyét -C. Gidm-nité huyét cn litpid mau Truyén manitol vn nhan va co’ ché bénh r clatiagsalLhuyét-tsong, naoai tre A. Giam dé Igc cau than 8. Tang tiét Kali tai éng than, C. Nhiém togg chuyén hoa -— 0, Dich chal li tte ndi bao ra ngoai bao ~~ n < Lai tiéu git Kali -—~ '81.Nguyén nhan cla ‘Suy tim tim A. Céc bénh lam ang [wu long tuan hoan 8. Cac bénh lam gidm lwu lgng tun hoan ©. Cac bénh lam gidm céng co tim @ Cac bénh lam tim gidm hoat dong Cac cu trén déu sai 82.Thay ddi chi tiéu hoat d6ng khi guy tim Ax Gidm hoat déng than kinh oa c Phi dai co tim C. Glam thé tich mau D. “fang téc d6 tuan hoan E. Giam huyét ap tinh mach 83 .28¢ biéu hién cia suy tim trai Caen: phdicdg B. Ganto C. Phu toan than D, E Gidm bai tiét née tigu U tré mau ngoai vi PD14 “an phai thudng khong ¢6 biéu hu phdi cdp meals B..Ganjo— C. Phirrigoai bién~ D.. Giam bai tiét nude tigu — E. U tré mau ngoai vi 85.C&n bang protid A. Cén goi ld c&n bang Nitrit Phai do lién tue trong 1 thang @ Can bang dong tinh thuéng gap & phy né c6 thai D. Can bang &m tinh thuéng gap & tr em dang phat trién E, Tat ca déu sai 86.Trong operon, gen kiém saat gen tae déng la A..Gen cdu trac B. JGen diéu hoa C. Gen khdi dng D. Gen gidi ma E. Chat kém ham. 87.R6i loan gen didi hda A. Do héa chat B. Dotia xa C. Do d6t biér gen @®pdo chuBi y khong bj tee ché E. Gay ra bénh thiéu mau hdng cau hinh liém 88.Hb bat thudng trong bénh Thalassemia ta do A. Gen chudi alpha khéng bi te ché Gen chrsdi beta khong bi tee: che Ox chudi gamma khéng bj tre ché Gen claudi delta khéng bi tre ché E. Tat ed déu ding , aSia Ma Oy, DAI HOC Y DUG TP. HO CHI MINH KHOA Y. BO MON MIEN DICH & SINH LY BENH Ho va tén: To: M4 Ding Lop: Y20uc owen Huéng dan: DE THI MIEN DICH & SINH LY BENH LAN 1 LOP Y3 CHINH QUY NAM HQC 2013 - 2014 Ngay thi: 19 thang 7 nam 2014 Chon cdu ding nhét: danh chéo’eau ding nhat vao phiéu tra (oi Thye hanh fam bai viét Théi gian lam bai thi: 55 phit Sinh vién phai dién day dui tén, 16p, 5. Bai thi nao kh6ng cé ui tén, lop, 13 sé bi huy bdHippocrate, due tn vinh la éng td cia y hc hién dai, 44 48 ra hoc thuyét vé A. 2 yéu t6: thé xdc va linh hén B, 2lyc: am, duong #. 4chataich: trang, 48, vang, den. D. 4 nguyén t6: Itra, khi, At, nude. E. 5 yéuté: kim, mOc, thy, hda, thd 2. Quan niém vé bénh tat cn c6 gid tri cho dén ngay nay, Bénh la dé ri logn 4 ch&t dich Bénh [a do o8 may sinh hoc bihurhéng ~~ Bénh 1a do ri loan can bang ngi mdi Bénh Ia do r6i loan cdc chat héa hoc Bénh [a do tén thong té bao - moom> . Sigmund Freud (1856-1939) cho. ing ‘bénh chi la san pham ota sy chén ép cia A. ¥ thite trén tiém there. B. link hdn trén thé xdc 6.’ ngoai moi trén ngi moi D. sinh hoc trén co hoc E. thé dich trén té bao |. Qua trinh bénh ly thuong tién trién va phat trig-qua nhiéu gial doan , goi la cac khau, khdu sau. eaung nguge tré lai khau trrée tam’cho tinh trang bénh ngay cang nging thém, 6 18 vong xoan A. bénhsinh B. bénh ly ©. bénh nguyén D. bénh hoc €. bénh can ; C3 convertase trong truéng hop hoat tac bé thé trong ca 3 con dudng Khi két hop them C3 sé t thanh ‘A. CA convertase B. C5 convertase C.-C6 convertase D. C7 convertase E. CB convertase Cr convertase trong truéng hyp hoat tc bé thé theo con diréng kinh aién va con duréng lectin hod toan gidng nhau voi n= 1va2 2vaa-- 3va4 4vas 3vas moopES 3 3 7. Khi cdc thanh phan bé thé tu. C2 dén C5 bi cat ra lam 2 manh a vd b, ce manh b thong bam én té bao dich, gitip cho cdc té bao thyc bao bat git dé hen, 66 a tac dung A. Opsonin héa B. anaphylactoxin 6. lam vo té bao dich D. héa huréng dng bach cau E, tang cuong é viém 8, Thanh phan twong duong véi C1s ota duéng kinh dién khi hoat tac bé thé theo dudng lectin la A MBLI 8 MBL2 Dc maspt D. MASP2 E. MASP3 9. O Bai thyc bao, khang nguyén ngoai sinh durge xt fy tai tdi ‘A. Phagosome B. Proteasome C. Lysosome 0. Phagolysosome- E, Phagoproteasome D 10.Cytokin do lympho Th tiét ra 48 hoat héa lympho B c6 tinh chat A. Chon toc + B. Dac hiéu DC. Khong aac higu D. Tay vao loai lympho B E. Tuy vao ban chat khang nguyén 11. So v6i dép teng mién dich thi 1, pha binh én’ dap ung mién dich thi 2 c6 thdi gian Dai hon Ngan hon Bang nhau Thay adi = Tuy vao ban cht khang nguyén A moop> 12. Lympho B 6 kha nang trinh dién khang nguyén vi Lympho B tng hep duge phan tl ph hgp i mé lop : Ad Boul i cow Dv * i Ev ~ 13. Lipid dye phan bé trong co thé & té bao va huyét tong c6 ac ciém ‘A. Lipid trong huyét tong luru thong dui dang ty do | B. Lipid dy tri trong té bao dui dang lipoprotein rf © 6. Lipid dy tee urge dy tr trong cdc té bao mo" D. Acid béo durge thuy phan tir mo mo * E. Triglyceride, phospholipid, cholesterol gn két voi albumin a4 14. Onguei inh tiéu dudng (type 1 ln type 2) gan tang san xuat ‘A. Chylomicron B, VLDL c. LOL D. IDL E. HDL 15, Chylomicron tan dur dec gan nhan din va bat gid nhe- A APOE 8. Apo B100 C. Apo Bas D. Apo A-lt E, Apo C-lll » 16. Thanh phan chi yéu gy xo vira déng mach dan dén cao huyét 4p Q A. Chylomicron 8B. VLDL C. IDL D. LOL €. HDL 17. Thudc sau day gay sét do ban chat thudc Ia cht gay sét ndi sinh: Erythromycin Thyroxin Atropine Epinephrine Interferon moop> 18. Yéu t6 tryc tiép gay tang diém didu nhiét (set point) fa: Vikhudn gay bénh cAMP. PGE2 . Chat gay sét ndi sinh Cyclo Oxygenase moo 19. Tac nh&n gay sét hang dau la: Bénh ty mién Bénh ac tinh Nim ky sinh tring Nhi&m khudn Thudc gay sét moo@> 20. Cac trudng hgp sau day cn didu tri ha sét, NGOAI TRU: C6 tin sir nhbi mau co tim Bong kinh Sét & tr em Phy ni c6 thai Sét cao trén 41 65.C moos %21. Chi tiéu sau day tang cao trong mau chi diém tinh trang viem cép: A. CRPY B. Héng cau A ¢. Tigu cu D. IgE E. 9G 22, Vai trd cita hé théng bé thé trong phan &ng viém 1a: A. Ly giai vi khuan- 8. Khu tri tac nhan gay vigm w+ CG. Ut ché hign tugng thyc bao D. Ue ché sy di chuyén cia bach cu E. Gitp siva chiza va lam tanh vét thong 23. Co ché chinh ciia hign tung hinh thanh dich vigm [a A. Tang ép suat thdy tinh 8, Gidm ap sudt keo £ G. Tac mach bach huyét D. Tang 66 nhét mau . E. Tang tinh th4m thanh mach » . . 24. Trong réi loan van mach tai 6 viém, hién tugng xay ra sém.nhét la: ‘Sung huyét tinh mach ‘Sung huyét dong mach U tré tudn hoan Comach . Dan mach D moom> 25. Té bao lymphé T cé cdc dc diém sau, NGOAI TRU: T CD4 trinh dign khang nguyén trén HLA lop 2 B. Buge biét hoa & tly xuong é ©. CéTCR D. C6 déu 4n CD4 hay COB E . Biét héa manh nhét & giai doan bao thai > B 26. T4 bao lymphé B 6 dc diém sau: O ngudi, dugc biét hoa & tui Fabricius B. Cé phan tiy HLA lép 1 trén bd mat 'D - 6. Epstein- Barr virus khéng thé gn [én té bao D. E. > Cé thy thé voi Fe (FoR) trén bd mat- . C6 giai dogn bit héa & tuyén ite rt Guan trong 27. Té bao khéng thuge nhém trinh dién khang nguyén [a: Té bao bach tude Té bao xde ngén tay TE bao lymphé B Té bao lymphé T. pecetd Té bao Kutfer im) moom> »6 28. Co quan lymphé trung wong sau day [a noi bigt héa lymphd bao B: A. Hach bach huyét B. Tuyén ter Cc C. Tay xvong D. Lach E. Gan 29. Thiéu mau huyét tén c6 cdc dae diém sau, NGOAI TRU: A. Sat huyét thanh tang . 8. Hong cAu Iwi tang.. t o C. Thé tich mau binh thuéng D. Bilicubin ty do gidm E, Hau hét la thiéu mau dang sac, dang bao 30, Bénh Thalassemie la bénh thiéu mau huyét tan c6 cdc dac diém sau, NGOAI TRU: C6 sy hién dién cia hdng cdu bia ‘ Héng cdu dang sAc dang bao (SE marc ao tedm trong tuy ddng hop tie hay di hop tt D. COHDF trén din di hemoglobin E. C6 thé gap & ngudi truéng thanh + 31. Bénh Ga hdng cdu nguyén phat cé nguyén nhan do: Sinh séng & ving ndi cao oct Tang sinh mot clone t&baogée lo. BB abst out Bénh tim bam sinh . D. ‘Bénh phdi tac nghén man tinh £. Undo x 32, Mat mau cp tinh 66 cdc dac diém sau, NGOAI TRUS: A. CO kha n&ng bi trir khi mat dudi 10% thé tich tun hoan B. Mat ca hdng cau va huyét trong Ee C. Thiéu mau dang sc, ding bao 0. CAn bu mau toan phan E. Vang da nang 33. Nguy hiém cia gidm Natri huyét la od thé dan dén_ A. Mat nude nhiéu hon mat Nati B. Thodi héa myélin cdu nao @ C. “Phi nao gay tang dp live ndi so D. Phi chi dudi E. Mat Natri nhiguhon mat nude 34. Réi loan can bang xudt nhp nude sé bidu hién chi yéu bang Tinh trang tang hoac giam thé tich nude trong co thé Tinh trang tang hod gidm ndng 46 Natri huyét tong ~ Tinh trang tang hoac gidm ndng 46 Kali huyét tong. ~~ Tinh trang tang hoac giam téng lwgng Natri trong co thé Tinh trang ting hodc gidm téng lugng Kali trong co thé moop>7 35. Co ché gay phi lam ting thé tich tuan hoan hou higu A. Tang dp suét thiy tinh B. Gidm ap suat keo £ ¢. Tang tinh thém thanh mach D. Tdc mach bach huyét E, Tang dp sudt tham théu 36. Két qud cn lam sang nao sau day cho két luan gidm Natri huyét that sy A. Ap sudt tham thdu huyét tuong giam .B. Tang Lipid mau A ©. Tang Protein mau D. Tang dudng huyét E. Ap sudt thdm thau huyét tuong binh thuéng 97. Hormone tuyén tuy thugng than cé tac dung lam tang duéng huyét: A. Glucocorticoid, © ob. Adrenatine C. Corticotropin #0. thyrotropin E. GH 38, Sy thay 481 sé lung thy thé insulin trong bénh tiéu during do co ché: A Ty dong B. piu tiét DG. Thanh thai D. Bidu hoa gidm bet : E. Bidu chinh 89, Didu sau day KHONG UNG cho bién chteng hén mé tang thdm thdu cila’bénh nan tiéu urdng: A. Thudng & bénh nhan tré, lira tudi thanh thidu nién B. LA hOi ching kiét nude sau sdc a AC. Xay ra khi bénh nhan khéng ung dU nude bu nude mat D. Thurdng 06 6 tidu duéng tip 2 E. Thuong & bénh nhan Ion tudi 40. Didu sau day KHONG DUNG véi tidu dudng tip 2: ‘A Cé ty khang thé khang thy thé insulin. B. Néng 46 insulin huyét binh thudng hay cao hen binh thudng * g C. Sélugng thy thé insulin trén mang té bao giam- D. Cé turong quan véi map phi- E. Célién quan he HLA 41. Sy 46t bién cia HbS trong bénh thiéu mau hang cau liém gay: A. Réiloan ty thé B. R6i loan hoat dng men tao nang liveng D.C. Gidmap hoa tan cia oxy HbS D. Gidm 46 hoa tan cila deoxy HbS. E. Mat cn bing oxy HbS va deoxy HbS a.8 42. Thiéu mau tan huyét trong bénh thiéu mau héng cau liém xay ra trén; ‘A. Nguy&n tién hdng cau B. Nguyén héng’cdu va base C. Nguyén héng cau da sac D. Héng cdu mang, E, Héng cau gia 43. Bénh Thalassemia cé thé 6 cac loai hdng cdu sau day, NGOAI TRU A. Hong cau hinh bia B. Hdng cau hinh giot nude C. Hdng cau hinh liém D. Héng cau hinh elip £. Hdng cau hinh cdu 44, Ky thuat finger print trong bénh thiéu mau hdng cau lim cho thay: A. C6 d6t bién acid amin 6 chubi beta cita Hb. B, HbS di chuyén t6i cye durong. C. Hb trong héng cau liém cé Glu & vj tri 6 cla chudi beta. D. Hb Acé Val & vj tri 6 cla chudi beta. 2 E> Hb trong héng cau liém cé chuéi alpha binh thudng. 45. Trong diéu kién-binh thuréng, chat nay cé thé la ban khang nguyén: A. Polypeptid. B. -Polysaccarid cao phan ti. ©. Lipid. D. Dai phan tir protein. E. Albumin, 48. Khéng nguyén duéi day khdng phai fa khéng nguyén phy thude Thymus: Khang nguyén nhom mau Polysaccharide. Khang nguyén ghép |. Cac chdt tal :. Khang nguyén 06 edu tric protein. mooe> 47, Chat sau day 6 tinh gay mién dich: Polystyrerie Amiang . Hapten |. Bai phan ti protein, . Polypeptid cu tao toan acid amin D. moogpr 48. Epitop nhan dign béi khéng thé va epitop nhan dién bdi té bao T 06 d3¢ diém ging nhau la: A. Chi nam & mat ngoai khang nguyén Ing ciia phan tir ). C6 dang edu hinh 8. C 0, E. Cé dang edu tric bac 3 assi gay wor vira ang mach te . A Yuk. 8. HO 3) ©. Di loang ton 0. LOL nhd, 63m de E, Glucose. 50 Hai thanh phan quan trong tham gia wao co ché chinh lam rang xo vira Dong ra gay,dién chteng tim mach: >= Bai thy bao va yéu t6 NFKB. Triglyceride va LOL. Chylomicron va HDL. Bach cdu da nhan ai toan va phosphatase kiém. Mast call va bach cu don nhan. mos@> 51. Tang tiét aldosterone tién phat gp trong: Suy tim. Hi cheng Cushing. U tly thurgng than. Hoi chéeng Conn, Hi chieng Down. D moom> 52, Ca ché chinh gay phi trong suy tim: Giam ap suat keo ‘Tang tinh thém thanh mach. ‘Tc mach bach huyét,._, R6i loan 4p sudt thAm thu ‘Tang Ap suat thuy tinh we B moom> 53,Khang thé qua dugc nhau thai | IgA . gD lM . IgG? . IGE p> D moo 54.7 bao mast va basophil o6 thy thé véi phan Fe cla IgA Igd igh IgG IgE- . € moop> 55.Hign turgng opsonin héa lién quan én FcR FoR y. FoR FoR 5 eee FoR 3 a pb moop>10 56.i9G qua nhau thal nh A FeRn 8, FoRm C. Fort D. FeRq E. FeRo Thuéc khang viém khéng steroid gay loét da day té trang do cdc co’ ché sau day ngoai trl : A. Uc ché men COX; fam giam qua trinh ting hgp prostaglandin & da day B. Gay déc tryc tiép qua co ché bay ion ©, Ue ché men COX. tam gidm qua trinh tng hyp cdc chét bao vé niém mac da day 0. E Anh huéng lén ngi mac mach méu gay tr tré tuan hoan lam thiéu mau cuc b6 6 da day. * . Tén thong tnyc tiép chat nhay ‘58 H.pylori lam tdn throng niém mac da day bang cac co ché sau day, ngoai try A. Cae chién mao xuyén thing mang té bao niém mac da day B, Cac Cytotoxin téc déng tryc tiép gy dc Ién té bao niém mac da day ©. Cac khang nguyén cila vi trling 16i kéo cc dai thy bao gay viém niém mac da day D. Phospholipase cia vi triing lam phn gidi chét nhay va tin thurong 2 lép phospholipid ota mang té bao E. Urease cila vi triing tao NH3 lam tén thuong té bao niérn mac 59.Benh nhan bj iéu chay do enterotoxin cia vi tring V.cholera gy ra * A Matnuée wu truong B. Matnuec dang trrongs C. Mat nuéc nhuge trong D. Mat nuéc hén hop E. Chimét nuée, khéng mét aién giai. 60.Co ché hap thu natri khong bj anh hudng khi bénh nhan bj tiéu chy tét dich 1a: A. Hap thy Natri tao dign thé 8. Hap thy Natri trung tinh C. Hép thy Natri di k&m voi Glucose D. Hap thy Natri thy dong E. Hép thy Natri di kem v6i kali 61.0’ bSnh han xo gan, néng G6 albumin trong mau bénh nhSn glam 18 do c&e co ché sau day, goal trie : A. Qué trinh ting hep Albumin & gan giam, B. Su-cung cép acid amine tt” bira an giam C._Técd6 thodi hoa Albumine tng, D. Albumine bj mt vao dich o& truéng E, Té bao gan gidm sé lugng 62, re nhan xo gan bj r6i loan déng mau la do cac ca ché sau day, NGOAI TRU: A. Gidm san. xudt cdc yéu #6 dong mau B. Céc mach mau bj tén thong dé vo" Z on C. Gidm tigu cau do curéng lach D. Té bao gan giam sé lvong E. Thidu hyt vitamine K B.1 ip tue es rego eur 1g da do viém gan, E, Vang da do téc mat ngoai gan, 64.Cac tru@ng hop vang da sau day cé tang bilirubin két hop. ngoai trie: Vang da do chat tec ché men Glucurony! Transferase cé trong sira me ‘Vang da do viém gan - Vang da do tc mat trong gan Vang da do 16i loan bai fiét bilirubin ( Hi cheng ROTOR) ‘Vang da do tac mat ngoai gan moomp> 65. Yu t6 dich thé trong mién dich dic higu A. interferon Br B. Khéing thé . Bd thé D. Protein C phan tng E, Lysozyme 66.CAc yéu t6 dich thé trong mign dich KHONG dac hiéu gdm cdc thanh phan sau,NGOAI TRU? ‘A Interferon B. Bd thd ©. Protein C phan eng 'D. Céc acid béo trong tuyén bay E. Lysozym 67.78 Bao Thugc min dich dc higu 1a A. Té bao NK B. Cc té bao lympho T. & c. Bach clu ‘trung tinh D. Bach cdu don nhan £. Bach cAu 4itoan 68.Mign dich khéng dac higu c6 cde d&c diém sau,NGOAI TRU A. Xudt hin & dgng vat 6 xvong séng 8. Dap ting tire thi AAC. Thanh phan dich thé 12 Interferon ,B6 thé ,Protein C phan éng.w i D. Thanh phan té bao la be don nhan,be hat ,tb mast E. Dap teng thi 2 nhw thi dau , 69.Dién tich khuy&ch tan [a ~ "A. Téng dién tich bé mat cla phdi B. Téng dién tich duéng dan khi C. Téng dién tich cde phé nang dugc thong khi tét va tudi mau tét - 0. Téng dién tfch fbng ngye £. ‘Téng-dign tich nhu mé phdi Bie12 7G.Réi loan giai doan thong khi do réi toan ot dong hd hdp 18 co ché cba cdc bénh sau ay, NGOALTRUL moore: . Git veo cot sing Cé chyéng Thude tre ché hé hp. Mang suéng di dong . Hen phé quan, 71.Suy hé hp a 2, phn loal theo lam sang A B, ©, o E. Khé thé khi hoai déng nhe .._Khé thé khi hoai dng nang .Khé thé khi nghi ngoi Khé thé (t khi hoat d6ng binh thueng ._Khé thé it khi hoat déng nhe 72.Qué trinh hé hdp duge chia lam 4 giai doan A. B. C aD. E y Théng khi, khuyéch tan, hd hap trong, hé hap ngoai Cir déng hé h4p, khuyéch tan, van chuyén, trao dBi khi Hé hap ngoaii, khuy&ch tan, van chuyén, trao adi khi Th6ng khi, khuyéch tan, van chuyén, trao aéi khi Théng khi, van chuy&n, khuyéch tan, trao a4i khi 73.Chitc nang cla nhom phi hyp mé lép | & i la moogr Phong ngiza thai loai manh ghép |. Trinh dién khang nguyén cho té bao B . Trinh dign khéng nguy€n cho t& bao T . Van chuyén khdng nguyén dén té bao trinh din khang nguyén - . Xtr Wy Khang ngyén a, a pha hop m6 & nguéi B. © D. E. A. durge goi fa nhém MHC urge goi ta nhém H2 . durge goi la nhém HLA, - Suge goi la nhém DNA =. ehinh fa nhém mau 75, Manh ghép bj thai logi chii yéu la do A B. E. ‘hé thdng mi&n dich cila nguréi nhan chéng fal nhém mau cia ngurdi cho. hé théng mién dich cla ngudi nhan chéng Iai khang nguyén HLA ctia ngudi cho.- - hé théng mi&n dich cia ngudi cho chéng lai nhém mau cia ngudi nhan |. -h théng mién dich cia ngurdi cho chdng Iai Khang nguyén HLA clia ngudi nhan bat trong hop vé gidi tinh gitra ngurdi cho va ngudinhan 76.Sy lién két gidra mot bénh vdi mét allele HLA dac biét nao dé cé nghia fa A B. Cc. 0. E, . C4 thé nao mang allele 46 56 bi mc bénh , |. Ca thé n&o mang alllele do c nguy co mac bénh cao hon’ Phan tir HLA durgc ma héa bai allele a6 bj khiém khuyét Allele d6 sé dan dan bi mat ai . C4 thé nao mang allele 66 sé khéng bj mac bénh &8 13 77.Cac bénh ly sau day 1a bidu hién cia hién tung phan vé bé phan NGOAI TRU" A. Hen phé quan . cham May day ‘Séc phan ve ¢ Vier mai di eng 8 D ¢. . EL 78. This pham gay ra sc phan vé 18 do A. Téc dung ciia cytokin B. Tac dyng sinh hoc cla héa chat trunig gian- £ XK “QC. Tac dyng cia epoetin O. Tut huyét dp : E. Réiloan vi tun hoan i 79.Co ché gay tin thyong trong qua man muén ja do A. Lympho T va cae cytokin B. Tac dung sinh hgc ciia héa chat trung gian« a C. Khang thé gay déc té bao D. Phirc hyp khang nguyén - khdng thé E, T& bao mast va bach edu ai kim » 80.Mét thi dy din hinh cho bénh ty qué man type If A. Bénh dj tng B. Bénh tén huyét do khang thé chéng hdng cdu~ £ ©. Bénhatopy- D. .Bénh suy gidm mi&n dich E. Bénh viém da khép dang thdp 81,Trén bénh nhan suy thn, Jidu lugng thudc sir dung trén lm sang sé dugc didu chinh theo A Néng 46 creatinine mau B. Néng a6 urea mau C._H@ sé thanh thai creatinine - D. H@ sé thanh thai urea E. pH mau 82.Céc bidu hién sau day ta bidu hién chinh cla tinh trang r4i Idan chirc nang than, NGOAI TRU Réi loan thai triv cdc chat phé thai nhy urea. Réi loan ndng d6 cdc chat dién giai Réi loan chuyén héa cdc chat nhur albumin, bilirubin... R6i loan can bang nuée . Réi loan can bang acid - base mpop> 83.C4c nguyén nhan sau day t& nguyén nhdn chinh gay ra suy than man, NGOAL TRU. A. Chat d6c déi voi than nhw hemoglobin... B. Bai thdo auéng C. Tang huyét ap... ie D. Viém edu than E, Than da nang14 84,Thé tich nude tidu trong ngay phy thuge vao nhiéu yéu t6. Trong truéng hgp tut aes p (thi du: xudt huyét), thé tich nude tiéu giam 1a do. A. Ong gép tré nén khéng th4m d6i véi nude B, Gidm tai hdp thu & éng than C. Tryc renin-angiotensin bj tre ché D. Gidm lugng mau dén thén va gidm 46 thanh loc cu than E. Gidm dién tich mang loc cau than 85,D4u hiéu nao sau day la dac trung cho nhiém kiém hé hap: A. Gidm théng kh. B._ Tang Kali/ mau. C. [HCO3+ } tang. D. Hi chéeng tetanye E. Gidm Natri ‘mau 86,Khong tréng anion (anion gap) durge diing a8 han Jogi nguyén nhan olla Nhi&m toan chuyén héa. Nhiém kiém chuyén héa . Nhim toan hd hap Nhi&m kiém hd hap . Réiloan can bang dién gidi Pe meee 87.Nhip thd Kussmaul trong bénh anh nhigm toan chuyén héa la do ‘A. Dap ting bi triv ctta he dem 5 B. Bap tng bitrivctiathan C. ‘Dap tng bi trv cia hé hap D. eB r i i 1 | .. Dap tng bi triv ctia than kinh Bap tng bu try ctia ndi tidt 88.C4c nguy€n nhan sau day c6 thé gay ra nhi&m toan chuyén héa, AI TRUE A. Suy than, B. Tidududng. > z a Tiéu chay. E |. Non di kéo dal.” . Nhiém acid lactic aDAI HQC Y DUQC TP. HO CHI MINH KHOA Y \ BOMON MIEN "MyDICH & SINH EY BENH *\ Ho va tin: TE Ot vee op: DE THI MIEN DICH & SINH LY BENH LAN 1 a LOP.Y3 CHINH-QUY NAM HQc 2012 - 2013... Ngay thi: 06 thang 7 nam 2013 Huéng dan: @ Chon cau ding nhat: © Thyc hanh lam bai viét © Thdi gian fam bai thi: 55 phat © Sinh vién phai din day di t&n, lop, 16. Bai thi nao khéng c6 dil tén, 6p, t6 8& bi huy bd. nh chéo cau ding nhat vao phiéu tra 101DALHQC Y DUQC TP, HO CHI MINH KHOA Y Be MON MIEN DICH & S INH LY BENH Heviiane Oe nan ble To: $t vee Lop: DE THI MIEN DICH & SINH LY BENH LAN 1 LOP Y3 CHINH-QUY _ ; a . NAM HOC 2012 - 2013.: + : Ngay thi: 06 thang 7 nam 2013 Huéng dan: © Chon cau dung nhat: danh chéo cau ding nhét vao phiéu tra di © Thyc hanh lam bai viét © Thdigian tam bai thi: 55 phut © Sinh vién phai dién day du tén, lop, t8. Bai thi nao khéng cé di tén, Iép, 8 sé bi huy bd.|. Khang thé qua dug nhau thai la A IgA B. Ig IgM Bese . E. IgE . Té bao mast va basophil co thy thé voi phan Fe cia A. IgA B. [gD C. IgM ig IgE 7 Hign tung opsonin héa lién quan a&n FoR a FoR y— . S FeR p . O. FoR E. FoR A . IgG qua nhau thai nho SEINE, yet |. FeRm C. FeRt “BL FeRq E. FeRo ..-Thude khang viém khdng steroid gay loét da day td trang do cdc co ché sau day ngoai trv A. Ufc ché men COX, lam gidm qua trinh téng hyp prostaglandin 6 da day . .Gay déc trye tip qua co ché bay ion : Uc ché men COX; lam gidm qua trinh ting hop cdc chat bao vé niém mac da day D, Anh hung Ién ni mac mach mau gay W tré tun hoan lam thiéu mu cuc bd & da day. “E. Tén thong truc tgp chat nhay ‘ : H.pylori lam tén thuong niém mac da day bang cdc co ché sau day, ngoai tri Cac chién mao xuyén thiing mang té bao niém mac da day - B. Cac Cytotoxin tac déng tryc tiép gay d6c 1én té bao niém mac da day ©. Cac khéng nguyén cia vi tring 161 kéo cdc dai thyc bao gay vim niém mac da day~ * D. Phospholipase ctia vi tring lam phn giai chat nhay va t&n thong 2 lop phospholipid cila mang té bao : E. Urease cia vi triing tao NH3 lam tén thong té bao niém mac Bénh nhan bj tiéu chy do enterotoxin cia vi tring V.cholera gay ra Mat nuéc wu truong Ons nwéec ding trong - Mat nude nhuge trong D. Mat nuéc hén hop E. Chimét nude, khéng mat dién gidi. cen : #15.Té Bao thude min dich dc hiéu la Té bao NK Cac té bao lympho T €. Bach cu trung tinh D. Bach cdu don nhan E, Bach cau ai toan 16. Mi8adich khéng dac higu cd cdc dac diém sau,NGOAI TRU, “Sa hign & dong vat c6 xong sing” / ap Ung tire: ‘Thanh phan dich thé [a Interferon ,Bd thé ,Protein C phan Gng,w ‘Thanh phan té bao l& be don nhn,be hat ,tb mast ~ > Bap tng thi 2 nhy thi ddui 17, Ngui 8 ra Phuong phdp thyrc nghigm trong Y hge, dat nén méng cho Sinh Ly Bénh Hoc 18 Hippocrate ; Claude Bernard ; C. cartes: 0. Pavlov i E. Sigmund Freud 18.Bénh 1a do réi loan 4 chat dich co’ ban, dé 1 quan diém cia “B Hippocrate 8, ‘Claude Bernard. ©. Descartes bit bd ol jo betel bo, Spon bic Vac ). Pavlov sin of far ap an" (€ Soanfon't 9 BWA doe x cas BETH uyén nhan va diéu kién gay nén mot bénh dug goi la yéu td Nace nguyén , |. Benh sinh C. Bénh ly D. B6nh hoc E. Bénh nhan 20. Bénh sinh hoc la mén hg nghién ctru va co ché phat sinh, phat tin, tién trién va A. Vong xodn bénh ly B. Lanh bénh 7 C. Ti vong OL két thie ofa bénh €. Ghéng lai.bénh 21.C3 convertase trong truéng hgp hoat tac bé thé theo con duding kinh dién la C4b C4b2a/ ©. Cab2b D. Cab2a3a E. Cab2a3b! | 5 22, Thanh phan tuong durong voi C1s ota dudng kinh dién khi hoat tac bé thé theo duéng lectin fa A MBL : 8. MBL2 ™ G MASP4 eS MasP2 ~ pr z: MASP3 en 23. Trong con dung t&t, phire hyp tong durong v6i phirc hyp ca7gge trong duéng lectin t& A C3 a a B.C3b € 6. C3bB C3bBb & C3bBbab/ / 24.C3 convertase cila moi con duréng hoat tac bé thé, khi két hgp thém C3b sé tre thanh - £4 convertase ~ . cs convertase’ ~ . C.. C6 convertase D. C7 convertase E., C8 convertase 25.Khéng nguyén ngoal sinh sau khi durgc xr ly thanh cc dogn peptid, dogn peptid mién dich trot ~ 86 durge két hyp voi phan tir phu hyp mé lép Il tai ‘A. Proteasome B. Phagosome sosome Phagolysosome Phagoproteasomé 28.MOt trong nhiing tin higu thir nhét gép phan hoat héa lympho TCD4+ l& phan tir CD3 ctia ‘TCD4+ phai phi hop voi ‘A. Nhém phi: hop lép | cia té bao trinh dién khang nguyén Gio hii hep lép Il cia té bao trinh dign khang nguyén < Phan t/CD80>pia té bao tinh dién khang nguyén D. PhAn ti? CP86/ciia té bao trinh dién khang nguyén E. Phan t By ce t& bao trinh dign khang nguyén 27.Lympho B truéng thanh, chva tiép xc voi khéng nguyén ln ndo, khi bat dugc khang nguyén ac higu va c6 sy try gitip See ee Se tbe Loe thantrong aoa khang thé thuge lop A. IgA B. Ig. C. We ; x ay sy tasiecemmmospacemecnsesesmncie! 26 28. So x¥idp ting min dich thi 1, pha binh dn & dp tong min dich thi 2 06 théi gian Dai hon" : B. Ng&n hon C. Bang nhau D. Thay di E. Tuy vao ban chat khang nguyén 29.Dj vat thanh quan gy J Abi loan giai dogn thong khi do giém cir dng ho hép poke Jas Réiloan gia doan thong khi do te nghén-durdng dn ko VAT, we . Réi loan giai doan khuéch tan do réi loan dign tich khuéch tén D._ R6rloan giai doan khuéch tan do réi loan mang khuéch tan E, Réi loan giai dogn khuéch tan do r6i loan higu s6 khuéch tan 30. Uro.5X6 trung tam hé h4p do ngd déc thud ngiigayra + Réi loan giai doan théng khi do.gidm co’ hoc hé hp * B. Réi loan giai dogn théng khi do tic ngh&n dudng dan khi C. Réi loan gia doan khuéch tan do réi Idan dién tich khuéch tan D. Réi loan giai doan khuéch tan do réi loan mang khuéch tan . Réi loan giai doan khuéch tan do rdi loan higu sé khuéch tan 31,Giam ap suat khong khi tho gay nén A, Giam dign tich khuéch tan (8), Gidm higu sé khudch tan eda oof ©. Gidin higu 86 khudch t4n cola COZ D. -Gidm a day mang khuéch tn yy Gidm kha nang cla mang khuéch tin 32. Viém phdi thiy gay réi loan giai doan A. Hit vao 8. Afiong kht . khuéch tan7 : . van chuyén E. trao ddi kh gidra gian bao va té bao 33. Bién chéng vét thong {au [anh ciia tigu duéng do cdc co ché sau, NGOAI TRU: A. Bénh nhan 6 co dia thuan lei cho nhi&m tring. 8. Dudng la méi trurdng thich hyp cho vi tring phat trién, ©, Kha nang thyc bao cia bach cau giam. op mang nhay trén da gidm kha nang bao vé da. een Wy ty mién.~ Y€y! t6 KHONG lién quan co ché gay bién ching nhiém toan cla tiéu dong: Thiéu insulin, Tang acid béo & gan. Tang tong déi hay tuyét d4i glucagon. Q Hoat héa hé men COMT.~ 20 CR Tang qué trinh oxy héa mo & gan. a| | 4 7 635.Yéy 18 KHONG thudc co ché gay bién — ching mach mau én cia tiéu duéng: © Nhigm tring. \ ‘Glucose huyét lic 66i va sau khi an. ~ 7 C. Réitgan lipid huyét.- D. a0 huyét ap. yl mene. Za 36. ChSt G6 khang tac dung cia insulin quan trong nhat ‘Acid béo ty do.. 7 |. Glucagon. C._Thyroxin. 0. Glucocorticoid, E. GH 37. Héng cau liém trong bénh thigu mau hdng cau idm a8 vo KHONG do co ché sau: A. Hinh dang giéng cai tiém. . (Mat kha ning uén cong khi qua mach mau naa Héng cau bj dinh vao noi mac mao mach. ‘Tang sn hdng cau trudng thanh gay t&e mach. E. Héng cdu ludi 06 mang dé dinh két. C6 abt bién acid amin & chudi beta cla Ho . HbS di chuyén toi cue dong. « C. Hb trong héng cau lim cé Glu & vj tri 6 cia chudi beta~ D. HbA 6 Val vi tl 6 ota ‘chudi beta, E. Hb trong héng cau liém c6 chudi alpha binh thong. 38. “Bete print trong bénh thigu mau hdng cau liém cho thay: 39.Hb trong bénh thigu mau hdrig cau liém co: i hoa tan cla oxy HbS gidm. Be héa tan cia deoxy HbS giam. ~ Dang oxy HbS bj két ta dui dang s¢i lam hdng cAu bién-dang Hiah tide. D. BO ba mat ma bét thudng & gen DNA 1a CTC. E. Glué vit 6 cia chudi beta. ar —&) 40.Didu sau day KHONG DUNG vé bénh Thalassémie: ‘A. Héng cau hinh bia. 7 B. HDF chiém #116 cao hon nhiéu so vei binh thuéng. . Gen chubi y khong bi Ge ché. (Héng.c&u hinh tim.” ~ Bénh hay xuat hién & ving Dia Trung Hai, 41, Trong diéu kién binh thueng, chat nay 06 thé [4 ban khang nguyén: A. Polypeptid.~ Polysaccarid cao phan tt. Lipid,~ + ook Gh tha D. Dai phan tir protein E. Albumin. ie a RE EB SOPOT I REESE 2,42. Day la cht 06 tinh gay mi&n dich: ‘A. Polystyrene. B. Amiang. *Slypeptid cu tao toan acid amin D. Oras cu tao acid amin dang. 7 E. Acid nhan tinh khiét, 43, Epitop khang nguyén nhan dign béi té bao B (khdng thé): ‘A. Chicé dang céu hinh. 8. Chi cé dang chu. : C. O'phan cuén vao trong cia phan tir 5 Aiea 19 mat tiép cn durgc ota phia.agaai cu tric khang nguyén. ~ Khéng 6 tinh éac higu 44,Khang nguyén duéi day c6 dap img min dich khdng 6 trl nho: Khang nguyén nhém mau ° p lysaccharide - 4 ©. Khang nguyén ghép 0. Cécchdttai E. Khang nguyén cé cu tric protein. 45. Thi pham chinh gay xo vira dong mach la: A. VLDL 8 HDL, LDL tong, 16n. LOL nhd, dam aac. ~ Glucose. 46. Hai thanh phan quan trong tham gia vao co ch chinh lam mang xq -y(ra bong ra gay bién ‘ching tim mach la: A Dai thyc bao va yéu té NFkB. tiglyceride va LDL. ¢, Chylomicron va HDL. (D. Bach cdu da nhan 4i toan va phosphatase kiém. i E. Bach chu da nhan ai kiém va lympho bao. 47. Tang tiét aldosterone tién phat gap trong: A. Suy tim. B. Hi chieng Cushing. C. Utily thugng than. D. Utuyén gidp. HGi chéng Conn. 7 48.Suytich lOy b&t throng VLOL lau apo-Clll lam tang LDL nhé, dam d&c do r6i loan host ong. i Thy thé nh&n PPAR alpha ~ ! 'B. Thy thé nhan PPAR beta ©. Thy thé nhan PPAR delta “B.Thy thé nhén PPAR gamma E. Thy thé nhan PPAR sigma B9 | 49. Thude sau day gay sét do ban chat thud la cht gay sét: A Erythromycin _ B. Thytoxin ©. Atropine Epinephrine Interferon i | | 3 10. Sy gia tng thn nhiét khi phat sét la do co ché sau: 2 gay ting diém aidu nhigt > teAny Crowe gay ting diém aidu nhiet_— . Réi loan trung tam digu nhist D. Tang sn nhiét, glam thai nhigt E, Déct6 clia vi khudn gay sét a a 5 Oe sinh hgc ota ch&t gay sét ndi sinh ka: ‘Tang héa huéng déng bach chu / + qian Fr @ 2m tithanh , det Aabintd. We ché mién dich dich thd L- C. Uc ché mién dich té bao os D. Ucché ting hgp bé thé . | E Tang hdp thu eétva kém . 52.Diém edu nhiét (set point) tang hon binh thuéng trong tru’ng hop: gm néng | Sét . | C. Ha than nhigt D. Tang than nhiét E. Than nhigt binh thong | 53.Quan niém sau day vé phan @ng viém KHONG DUNG: | ‘A. Viern (a phan tng toan than \Viém c6 hai trong mét sé tru’ing hop een thudc vé thanh phan mi8n dich 6&c higu / i Viémn f& mot phan teng c6 igi nh&m loai trir_yéu t6 gay bénh E. Viém chiu tac dong ota hé than kinh va he noi tlét " 64.Vai tr cia hé théng bé thé trong phan ting viém Ia: 17" A. Gidp sia chia va lam lanh vét thong tra tac nhan gay vim 1 Opsonin héa déi tung thyc bao f. Uc ché sy di chuyén cilia bach cu £, Uo ché hign tugng thyc bao 55. Vai trd cila hé théng déng méu trong phain ting viém fa: A. Héa huéng dng bach cau jn héa d6i tugng thye bao ‘Khu tr tac nhan gay viém D. Ly gidi vi khudn E. Tao phic hyp tén ofing mang10 56.Co ghé chinh hinh ttrdnh dich vigm la: ‘Ang tinh thém thanh mach ~7 ing huyét tinh mach ung huyét dng mach mach E. Dan mach 87. Té bao lymphé T 06 cdc dc diém sau, NGOALTRU:, A. T.CD4 nh@n dign khdng nguyén tinh dign trén HLA Kp 2 B. Buyge biét hod & Thymus G, COTCR | dau 4n CD4 hay CD8 gt hoa manh nhét & giai doan day thi 7 58. Tuong bao 06 cdc dac diém sau, NGOAI TRU: A. Sn sudt khang thd - B. Duge bigt hod tir #8 bao lympho B “ C. Khéng cé Ig ba mat ‘Khong of tri.nhé mi&n dich - San xudt bé thé 59.Co quan lymphd ngogl vi &: Juy wong TS chirc lymphé & niém mac 7 . Thymus D. Vang drei 481 E. Toi Fabricius. 60. T6 bao khdng thude nhém trinh dign khdng nguyén 1a: A. Té bao bach tugc. B. Té bao xde ngén tay . T8 bao lymphd B - & bao lympho T ” - Tébao Kuffer 61.Bénh Thalassemie la bénh thiéu mau huyét tan 06 cdc aac diém sau, NGOAI TRU: ARCS sur hign dign cia héng cAubia / (8) Hang cdu ang s&c d3ng bao % Mite a9 trdm trong tay ddng hyp tc hay di hop D.“C6 HOF trén ign di hemoglobin E. C6 th8 gp & ngurbi trong thanh 62. Thiéu mau do thigu st c6 thé do céc nguyén nhan gau day, NGOAI TRU: A. Viém kéo dai i Wisk 4, gedit B. MAt méu man CAtdaday Suy than man — 16 so sinh thiéu thang“ searensret *i | 11 63. Thiéu mau huyét tn 66 cac dic diém sau, NGOAITRU: ‘A. St huyét thanh ting.~ BL Héng cau lurai tang ~ Thé tich mau binh thudng. Bilirubin ty do gin E, Hau hét la thiéu mau dang sdc, ding bao. 64. Bénh ly thiéu mau huyét tén.do khiém khuyét & mang hdng cau la: Bénh Miikowski Chauffard (Bénh hdng edu hinh cu di truyén) ~ B. Bénh hdng cau hinh lim C. Bénh Thalassemia \ D. Bénh thigu men G8PD \ E. Bénh sétrat 65.Gen ctia HLA 06 cdc dac trung sau day, NGOAI TRU A. Cé bibu hign ddng troi. ~ . B. Bigu hign ed ciia cha in cliame ~ ©. C6 tinh da hinh (polymorphism) ~ D, C6 nhiéu gen ma héa cho phan ti nhém phi hyp mo ~ itn trén nhi&rn sic thé 15 Ace Nhe ogy Nee 66. Yéu t6 quyét dinh manh peptid KN sé duge trinh dign hode trén phan tir HLA I6p | hoac trén ph§g tir HLA lop I 1a On dai cla manh peptid KN Ngubn gc . Thanh phan cu tao cia man pejtid KN D. Con dubng xir iy manh peptid KN trong té bao trinh dign KN E. Ai lye gitra manh peptid khang nguyén véi phan ti HLA 67. Kha nang @ép tg voi khang nguyén cia té bao T bi han ché trong nhém phi hep mé 1a do A. Tat ca khang nguyén phai dupe xi ly va trinh dign cho té bao lymph da hoat héa B. Tt ca khang nguyén phai dugc kiém tra tai proteasome trrdc khitrinh dign cho té bao lympho e C. Khi co thé bj nhiém khudn, tat ca té bao sé trinh khang nguyén-trén phan tir HLA ‘ep! : Py Phan tir HLA gn ién khang nguyén dic hi TCR "TCR phai nhn digi khang nguy€n cing voi phan tik HLA ~ 7 88, Nguoi ta nhdn thay ob méi turcong quan chat ché gitra bénh viém dinh dét song voi HLA-B27 & trén ngudi. Biéu nay c6 nghTa la ‘A. Ngwéi cé HLA-B27 chdc chén sé bj bénh viém dinh at séng. B. Nguéi cé HLA-B27 chdc chdn khéng bj bénh viém dinh dét séng. C. Ngudi cd HLA-B27 it ¢6 nguy co mac bénh viém dinh dét séng so véi nhOng ngudi héng 6. hee 6 HLA-B27 c6 nguy co mc bénh viém dinh aét s6ng nhiéu hon so véi nhong ui khong 06. E. Nguoi cé HLA-B27 c6 nhiéu khé khan trong diéu tri viém dinh aét s6ng nhiéu hon so V6i nhiing ngwdi khéng cb12 69. Cac bénh ly sau day 1a bénh ly qué m&n type IV, NGOAITRU A Uhat 8. Vim da tiép xtc - Om huyét do bat tong hop vé nhémméu ¢ Phan tng tuberculin 4 E. Cham do tiép xtic ~ 70.Bénh huyét thanh la do Phan tng qua man tire khdc 4 é Ome ding qué mn do phitc hgp min dich tu han $) Phan tong qué m&n qua trung gian té bao 4 D. Phan tng qué mn kich thich E, Phan ting dc té bao phy thugc khang thé 2. 71.Khéng thé tham gia vao phan tng qué mn type la . A IgA . 8. IgM C. IgG D. IgD IgE 72, Phan tng qué m&n type I 1a tL A. Phan tng qua mén tickhéc B. Phan tng qua-m&n do phirc hgp min dich 3 2, Phan tng dc té bao phy thugc khang thé. 2 | D. Phan tng qué mn qua trung gianté bao 4 E. Phan @ng qua m&n kich thich 73. Dau higu nao sau day Ia dc trung cho nhiém kiém hé hap : : ‘A. Gidm thOng hi. f as 8. Tang Kali/ mau. 4 [HCO3* } tang. ey teh Al hid poe Hoi chrng tetany” yu, gs Sued wh atm WO RAE f Ghe Myst E. -Gidm Natri /mau Wa. | 74.Cac nguyén nhan sau day cé thé gay ra nhim toan chuyén héa, NGOAI TRU: 5 of A. Suythan. Uthan toy, » kh oa ngaas Lee bebagt B Tiduduong. 5 Pv avi be eugchm. ‘ ‘| Tiéu chay. > wth bitadsmab. 1 Jon 61 kéo dai. © Nhiém acid tactic ¥ ~ 75.pH/mau binh thuéng dao d6ng trong mot giéi han rAt hep tir } A 7,55-7,65 7,45 ~ 7,56. 37,35 - 7,45. 7,25 ~7,35. €. 7,15-7,254 13 a t6 gidp phan loginguyén nhan cia nhiém toan chuyén héa la RSJ A. Nong 46 aurong huyét a et B. D6 tham thdu huyét tong C. Néng 46 ion H+/ mau | Khoang tréng anion “ 5 ". Nong d6 bicarbonat 2 77.Th8 tich nude tiéu trong ngay phy thud vao nhidu yéu td. Trong truéng hep tyt huyét 4p (thi f dy: xuat huyét), thé tich-nudéec tiéu gidm la do A. Ong gép tre nén khéng thAm déi voi nuée B. Gidm tai hdp thu éng than Truc renin-angiotensin bj tre ché 5 Osim lugng mau dén than va gidm d@ thanh loc cau than Gidm dign tich mang Igc edu than 78. Hoai tir éng than cp la tinh trang A. Suy than cdp trréc than &__Suy than ep tai than ©. Suy than cp sau than D. Suy than din tién nhanh E. Suy than khéng hdi phuc He sé thanh thai creatinine. SS Hé sé thanh thai urea. G._Néng 46 creatinine/ mau. ‘D) Thé tich nuvéc tiéu/ 24h » Néng d6 ures mau. 79, Ne gidp chting ta danh gia chinh xdc nhat chive nang than la 80.Tinh trang tang ni-to huyét ( azotemia ) la A. Tinh trang gia tang nhirng chét ¢6 chira ni-to nhu NH ... trong mau. Se trang gia tng nhOng ch&t cé chiva nite mA khéng phai la protein nhu uré, reatinine... trong mau. ”C. Tinh trang gia tng nhiéng chat protein c6 chira ni-to nhu glutamin trong mau. i D. Tinh trang gia tang nhiing chat cé chita ni-to nhu NzO... trong mau. a E.. Tinh trang tang u-ré huyét (uremia) 81.Nguyén nhan gay gidm thé tich A. Bai thao duéng B. Thia ADH i Viem edu than Thidu Aldosterone E, Anit mudi 82.Co ché gay phi lam tng thé tich tuan hoan hou higu A. Tang ap suat thiy tinh B. Gidm ép sudt keo ©. Tang tinh thdm thanh mach BQ. Tac mach bach huyét Tang ap suat thdm thdu .14 83. Nguyén nhan va co ché bénh sinh ola tang Kali huyét tong ‘Sy dich chuyén Kali tir ngogi bao vao ndi bao ~® roles toan chuyén héa— ~ Nhiém toan thé ceton D. Nhiém toan do éng than E. Non i kém tiéu chay cép * 84. Két.qua can lam sang nao sau day cho két Iuén gidm Natri huyét that su JAp sudt thm thdu huyét trong giam ‘Tang Lipid mau ~% C. Tang Protein mau& D. Tang dueng huyéte E. Ap suat thdm thu huyét tuong binh throng-S 85. Lipid duc phan bé trong ca thé & té bao va huyét tuong 06 dac diém A. Lipid trong huyét tong lwu thong dui dang ty doQ Lipid dy tro trong té bao dui dang lipoproteimQ Lipid dy tro dug diy tri trong cAc té bao me~ D. Acid béo dugc thuy phan tr mé mo-© E. Triglyceride, phospholipid, cholesterol gén két véi albumin SS 89.0 nguroi bénh tidu duéng (type 1 fn type 2) gan tang san xudt Chylomicron * ) VLDL

x 88. Thé tich nuéc tidu trong ngay phy ites vao nhigu yéu t6. Trong truéng hop tut huyét (thi du: xudt huyét), thé tich nuée tigu gidm Ia % A Gidm din tich va tinh thém mang ee cdu than > B_ Ong gdp tréy nén khong th4m déi voi nuéc © Gidm tai hap thu & dng than D Truc renin-angiotensin bj trc ché {& Gidm lugng mau dén than va gidin 46 thanh loc cu than 3B‘ 1 | a a seas, BAI HOC Y DUGC TP. HO CHI MINH KHOAY . BOQ MON MIEN DICH & SINH LY BENH Hp va tén: 18: ——Lop: DE THI MIEN DICH & SINH LY BENH LAN 1 LOP DUG 3 CHINH QUY NAM Hoc 2012 - 2013 Ngay thi: 25 thang 11 nam 2012 Huong din: @ Chon cu ding nhat: 64nh chéo cau ding nhdt vao phiéu tra lai ‘© Thye thye hanh lam bai viét © Thdi gian lam bai thi: 60 phut © Sinh vién phai didn day ad tén, lop, t3. Bai thi nao khong 06 dd tén, Gp, td sé bi huy bd, a,288 so 3. Thar ty hoat tac bé thé theo dung lectin la Fs Hippocrate durgc ton vinh la Ong tB clay hec —hién dai vi Ong 06 cong téch Y hoc ra khdi Than hoe 1. Ong la ngudi dé xudng hoc thuyét vé 4 chat dich . Ong la bac si lam sang danh tiéng vao thoi o6 dai D. Ong la mét nha triét hoc danh tiéng vao thi od dai Ls E. Ong a8 ra phurong phap nghién ctu Y hoc on Quan nigm *Bénh ia sy du tranh cia finh hbn duy tri sy van dong binh thuréng thé xéc" thude vé nén Y hoe oS Trung quée ‘An a6 . Lama D. Hylap. E. Aicap |. Claude Bernard dug nhin nhan la ong t8 cia Sinh Ly Bénh Hoc vl ‘A Ong la nha sinh ly bénh gii dng thir la nha lam sang gidi (Ong la nguéi a8 xuéng hoc thuyét v8 4 chat dich ‘Ong a ra phurong phap thy nghigm trong Y hoc D. Ong gil thich bénh tat dya tién co’ sé vat chat E. Ong giai thich bénh tat dyva trén y hoc hién dai . Trong 3 bude ca phong phap thye nghiém trong y hoc, buée duy nhat eé thé mang tinh chs quan ia A. Quan sat CB bat oi thuyét C. Thre nghiém chéng minh D. Thy nghiém loai tir E. Khéng o6 burée nao ¢6 tinh chi quan 3. Thér ty hoat tac bé thé theo durdng kinh dign Ia P1401, C158 : eee a B. Ctq, Cts, Ctr. ©. Cts, Ctr, Cig. D. Cts, C1q, Cir. E, Ctr, Cts, tq... A MASP, MASP2, MBL B. MASP1, MBL, MASP2.. G. MASP2, MASP1, MBL. MBL, MASP1, MASP2 .c9 £9 co E. MBL, MASP2, MASP1 ....C’ r. Hoat tac b8 thé theo duéng tat khéi dau bang yéu té A ct B. C2 Cees c Esscree seem apa 5 Q 3 8. Trong ba con dutng hoat tac bé thé, giai doan Rodin tan giéng nhau la giai doan A. Bém mang B. Chuan bi C. Binh vi D. Khuéch dai (B® Tin cbng mang 9. Khang thé dug sinh ra trong mi&n dich thi 1.chd yéu thugc Iép A IgA B. ID 6. IgG gM €. WWE 10.S0 v6i mign dich thL4, khang thé duge sinh ra trong mién dich thl2 6 di lye voi khang nguyén manh hon B. C686 lugng thép hon . Can thé? gian tiém an lau hon D. Cé pha binh én ngdn hon E. C6 pha gidm suit ngan hon 41.0 bénh nhan Viém gan B cAp, khang thé HBcAb thudc lp AA 8. IgD CG. WE Dc LOM — 12. Khang thd lp IgG tir me sang con trong thai kj, 681 v6i dia bé la Min dich (Chad dng, € Thy dng . Bam sinh D. Thuduge E. Khong aac higu 19.) vat thanh quan gay: Réi loan glai Goan théng khi do gidm oo hoc ho hép Cor loan gial Goan théng kh do t&c nghén durong dan khi Réi logn giai doan khuéch tan do bat thuéng mang khuéeh tn D. R&iloan giai Goan khuéch tén do bat thuréng dign tich khuéch tan * E. R6ifoan giai dogn khuéch tén do bat thurdng higu sb khuéch tan 14, Ute.ché trung tam hd hp do ngo doe thudc ng gay ra: CBF Rél loan gia doan thong khi do gid co hoc ho hp B,, Réi loan glai dogn théng khi do t4c nghén dung dn hi .” R6i loan gial doan khuéch tan do bat thurémg mang khuéch tan D. Réilogn giai dogn khuéch tn do bat thurdng din tich Khuéch tan E. Réiloan gial Goan khuéch tan do bt thréng higu s6 khuéch tani 16. Giam 4p sudt khéng khi tha gay nén A. Gidm eg hoc hé hdp B. Gidm dign tich khuéch tan iam higu s6 khuéch tn cia 02 D. Gidm higu s6 khuéch tan cia COZ E. Gidm a6 day mang khuéch tan @LPhi phd cdp gay nén ie ‘A Gidém co hoc ho hép By Giam tich khuéch tan Gidm higu s6 khuéch tan ca 02 D. Glam higu s6 khuéch tan cia COZ E. Glam a9 day mang khuéch tan 17. Thuéc khang viém khong steroid gay loét da day té trang do cdc co ché sau day ,NGOAI TRU A. Gay dc tryc tiép qua oo ché bay ion B. We-ché men COX, lam giém qué trinh t8ng hgp prostaglandin & da day ~ @ Uc ché men COX2 lam giém qué trinh ting hop cdc chat bao v6 niém mac da day . Anh hung én noi mac mach mau gaythiéu mau cyc bo & da day. E. Gay thn thong tryc tiép lop chdt nhay_ 18. H.pylori [am tén thuong niém mac da day bang cdc co ché sau day ,NGOAI TRU “S @ Céc chién mao xuyén thing mang té bao niém mac da day B. Cac Cytotoxin tée dong tryc tiép gay dc Ién té bao niém mac ©. Cac khang nguyén cia vi tring I6i kéo cdc dal thyrc bao gay viém ni&m mac da day o. ). Phospholipase cifa vi trung lam phén gidi chét nhy va ton thong 2 Ip phospholipid oda mang té bao E. Men lipase ctia vi tring tao nén cdc géc NH4" lam tin throng t8 bao niém mac 419, Bénh nhan bi tigu chay do enterotoxin ctia vi tring V.cholera gay ra A. Mat nS Gru trong > © -mAtnuée ang trong ee C. Mat nuée nhuge truong D. Chi mat nuéc, khong mat dign giai E. Nhi&m kiém chuyén héa. 20.Coreht tp rat kg oh ring Kb hn bt chy Ben A. Hap thy Natri fgo igh thé 8 Hp thy Nat trang tinh @ Hép thy Natt di kém véi Glucose D. Hp thy Natri thy dong E. Hap thu natri di kém kall : albumine trong mau bénh nhan glam la do cc co ché sau day, A Qué trinh ting hgp Albumin & té bao gan gidm. . ° B. Sy cung cp acid amine tir bira &n gidm @ Téc 46 thodi hod Albumine ting D._Albumine bj mit vao dich o5 truéng E. Kh6i lgng té bao gan giém xo gan, ning 4ce csvespmeney st ad | 5 22. Bénh nhan xo gan bj r6i loan dong mau la do cdc eg ché sau day, NGOAI TRU: Gidm sn xudt cdc yéu 6 dong mau (Cée mach mau bj tén thong dé vor idm tiéu cu do euéng iach” Giam cung cp vitamin K tir bira &n Gidm hép thu vitamin K 8. céc tnrdmg hyp vang da sau day of tang bilirubin ty do.NGOAI TRU: A. Vang da do huyét tén ndi mach. B. Vang da @ tré so sinh G.Vang da do viém gan ang da trong hi ching DUBIN JHONSON E, Vang da trong hi ching GILBERT moe@p 24. Cac trréng hgp vang da sau day c6 tang bilirubin két hop, NGOAI TRU: fang da do chat ire ché pregnane 3B,20diol o6 trong stra me B. Vang da do vigm gan C. Vang da do tc mat trong gan D. Vang da trong Héi ching ROTOR: « E. Vang da trong hi chéing DUBIN JHONSON, 25. Trong cdc hormone sau Gay, hormone o6 tée dung ten Gena Ass aguas uti ote bosmone con lalla A. Corticotropin. B. Thyroxin. 6. GH ® Insulire E, Glucagory 26. TII6 tiéu dung tip 2 trén téng s6 bénh nhan tiéu dudng A 540%. : B. 50-55%. C. 60-65%. 0. 80-85%. {Ej 90-95% 27. Bién ching hon mé tang thdm thu trong bénh tiéu duréng do ‘A. Bénh nhan map phi, 8. Bénh nhan &n qué nhiu. G. Bénh nhan ubng qua nhidu nude. Loi tiéu thdm théu. Bénh nhan khéng thé udng dG nude bit nude mat 28. Chat i khang tac dung cia insulin quan trong nhatla Acid béo tr do. Ug Hon rion hay qo i. Thyroxin. &, Glucagon. 0. Glucocorticoid. “ o E. Adrenaline6 29. Trong Gon vj biéu hién gen (operon), gen ‘sau day kiém soat gen tac d6ng thing qua “ ' chat km ham oo : A. Gen chu tric. B, Gen khai agng. G. Gendidu hoa. | D. Gen giai ma. E. Gen chuyén ma 30, Ban cht clia thiéu mau trong thiéu mau hdng cu lid 1a (QD Thidu mau tan buy 8. Thiéumdu fu sit | ©. Thiéu mau do rBilogn mign dich, F : D. Thigu mdu dang s&c. E, Thigu méu wu séc. 22sv hign dign cia HBS Ay ra | A. Hing cdu hinh edu khi phan ap oxy thép. { a cu hinh bia khi phén 4p oxy thép. | cu hinh nbn khi phan dp oxy thdp. | dol inh ln pan poy . _Héng eau hinh béng ma khi phan ap oxy th4p 32. Trong bénh Thalassemia, Hb chiém da s6 1a A HbE. B. HDD. G. Hoc. (D Hor. E, Hbs 33. Vi trl epitop nhan dign bei khang thé 4 (BH Thudng bidu 16 & mat tiép cn duge cia hia ngoai cfu tric Khéng nguyén. a -— By Gphan-cudn vao trong eda phan ti, GC. Cé thé c& & mat ngoai hay & phan cudn vao trong ciia phan ti. . Tring véi cdc epitop nhan dign bai té bao T. E. Khong xéeqinhduge = 34. Epitop nhan dién bai t6 bao T C6 thé & ca hai dang: dang chubi va dang cfu hinh, Chi 6 dang chubi. ©. Chié dang cdu hinh. D. Do edu hinh khéng gian dug hinh thanh tir cdc phan tir xa nhau nhung do cu tric bac 3 ching tiép cn lai gan nhau. E. Bién dang tay méi trrdng | 35, Polysaccharide KHONG o6 dic diém sau | A. Cé nhidu epitop. B. Chic6 mot hay ft dic higu. C. La khang nguyén don dieu. dn la kh4ng nguyén manh. i La khdng nguyén Khéng phy thude thymus ‘ | | Bb.pave costa eae 7 36. Cac khang nguyén sau day tao dap teng min dich c6 tri nhé, NGOAI TRU" A. Protein 8. Chéttai, G. Khang nguyén ghép. CBE Polysaccharide. E. Khéng nguyén nhém mau 37. Th pham chinh gay xo vira dong mach la A Chylomicron, 8. Phospholipid. LoL. D. Acid béo. E. VLOL. 38. Hai thanh phan quan trong tham gia vao ca’ ché chinh lam mang xo’ vira bong ra gay bién ‘chimg tim mach ld PB- Bai thyrc bao va ybu 5 NFKB. B. Triglyceride va LOL. ©. Chylomicron va HDL. 0. Bach cau da nhan ai toan va phosphatase kiém. £. Mast cell va bach cu don nhan. 39, Téing tidt aldosterone tién phat gp trong A. Suy tim, 8. Hi chimg Cushing. G.. U tly thugng than. H@i chtrng Conn. E. Hi chimg Down. 40. Gidm huyét dp 1a m6t trigu ching nguy hiém do. BS Mau khong ii nui cdc m6 dac biét Ia tim va ndo. B. Bénh nhan sé bi ngat, . Bénh nhan bj thiéu mau. D. Bénh nhén s& bi d6ng kinh, E. Bénh nhan s& bj suy hd hép 41, BAt thung lipoprotein lipase lam ténig 42,.U6ng nhiéu regu lam VLDL E - B. IDL ©. LOL 0. HDL... f E. HOLC| 4 q a 43, Bat thuéng LDL receptor lam tng A. Chylomicron a9 B. VLDL E ©. IDL 5 “0. LDL ath E. HDL, Sep ‘44, VLDL trong mau tng 88 lam tng (trong huyét tung) ‘A. Cholesterol toan phan B. Cholesterol ester héa C. HDL cholesterol D. LDL cholesterol S& Triglycerid 45. Sy gia ting than nhigt khi phat s6tl& do cac co ché sau, NGOAI TRU “AC PGE; gy ting cidm didu nhigt B. cAMP gay ting diém didu nhiét C._Réi loan trung tam diéu nhiét D, Tang sin nhiét, gidm thai nhiet E. Bc t6 cia vi khuan gay sét 48. Réi Jogn chirc nding va, sero hhéa xdy ra khi phat s6t 13: A. .Gidm nhip tim CB? Tang théng khi A . Gidm nhu cau str dung vitamin 4 D. Tang dy triv glycogen E. Glam thé tich tudn hoan “7 47. Trang tam aidu nhigt hoat dong binh thuréng trong trurbng hyp: A Sétdo nhiém virus ; & ~"B.” Sét do Hen interferon” ~ er C. Sétdo phan tng qué m4n D. Sétdo hi khudn g Glam than nhigt do tip xtc véi mdi truéng lanh, 48. Dc tinh sinh hoc cia chét gay s6t ndi sinh fa: ‘A Lam gidm s&t va kém trong mau B. Uc ché mién dich dich thé ©. We chémién dich té bao D. Ue ch& ting hop bd thé © §-Lam ting age tinh eda vi khudn 49, Quan nigm sau Gay v8 phan ting vim khong ding: ‘A. Vim chiu anh huréng cia hé noi tet B. Vim chju anh hung cia hé thn kinh trung ong . C. Viém thuge vé thanh phan mién dich khéng dc hiéu D. Viém la mét phan tng c6 igi nhdm loai trir yéu té gay bénh ~£. Viém la mét phan ting eye bé| | 9 ‘50. Vai trd clia hé théng bé thé trong phan tng vier 1a: " A. Gidp sira chiva va lam tanh vét thong B. Co ché chinh gay dau C. Opsonin hod adi tugng thyc bao D, Uc ché sy di chuyén cia bach cau \ &. Ue ché hign tugng ly gidi vi khudn 51. Vai trd cia hé théng déng méu trong phan teng vim fa: ‘A. Héa huréng dng bach cau B. Opsonin héa d6i trong thirc bao ©. Corché chinh gay dau D: Gidp siva chia va lam lanh vét thuong E. Ly gli vi khuan §2.Co’ ché chi yéu cla sy hinh thanh dich viém la: ‘A. Tang tinh thdm thank mach \B. Tang 4p ye thug. tinh C. Tée sinh mach D. Tac mach bach huyét E, Gian apie keo 53. T& bao lymphé T c6 cdc dac diém sau, NGOAI TRU: A Céig bd mat B. Bugc biét hod & Thymus ©. CoTCR 0. C6 déu én CD4 hay CDs E. Céval td quan trong trong mign dich té bao 54.78 bao lympho B cb dc diém sau: ‘A. Cé nhidu & l6p vé sdu ca hach B. C6 val trd quan trong trong mién dich té bao “G: Cé thy thé voi Fe (FcR) trén ba mat D. C6 phan tir HLA [6p | trén ba mat E. Min nhi&m véi Epstein- Barr virus 58. Tuong bao c6 cdc aac diém sau, NGOAI TRU: ‘A. Sdn xudt khang thé B. Duge biét hod tir té bao lymphé B C. Khéng c6 Ig b& mat D. Cé vai trd quan trong trong min dich dich thé “E. Cé tri nh min dich 56.Cor quan lymph tung rong a: OQ Hath bach hyét C. "Mang Peyer 2. Tuy arong E. T8 chic lymphé & nim mac bs10 ? 57. Yéu t6 quyét dinh manh peptid KN s& duoc tinh dign hoc trén phan ti HLA Wp Iho’, ‘rén phn tte HLA lop Ila _ ‘A. B6 dai clia manh peptid KN B. Thanh phan cdu tao cia manh peptid KN ~G~ Coh dung xir ly manh peptid KN trong té bao trinh dign KN. D. Ailye gitra manh peptid khang nguyén véi phan tir HLA E. Chite nang cia manh peptid KN 58. Chirc nding cila phan tir nhém phis hep m6 l6p Il la ‘A. Trinh dign manh peptid khang nguyén (KN) cho té bao T CD8 B. Trinh dign ménh peptid khang nguyén (KN) cho té bao B ©. Trinh dign manh peptid khéng nguyén (KN) ¢6 nguén géc néi'sinh “B: Trinh dign manh peptid khang nguyén (KN) cho t8 bao T CD4 E. Trinh dign manh peptid khdng nguyén (KN) cho té bao don nhan thyc bao 59, Cc dc trung sau day la cia gen HLA, NGOAI TRU A. Cé bidu hign ddng tri B. Cé tinh da hinh (polymorphism) G. Cé nhidu gen ma héa cho phan tty nhém phi hop md ~B. Nam trén nhiém sécthé 15 E. Cé nhidu allele ‘60, Phan ng thai loai manh ghép la do bat turong hop ve ‘A. Nhém méu . B. Gi6i tinh cia ngurdi cho va nguéi nhan C. Tinh trang tin gia ngudi cho va ngudi nhan D. Tudi tdc ctla ngudi cho va ngudi nhan XE Nhém HLA 61. Cac bénh ly-sau day 14 bénh ly qué mén type IV, NGOAI TRU A _Uhat “B. Viém da 8p" ~ (GO) Tan huiy&t do bat trong hep vé nhém mau & Phan ting tuberculin E, Cham do tiép xtc 62, Phan tng Arthus la phan tng qué man A Typel B. Typell © Type tt © Type lv E, TypeV 63, Bénh huyét thanh la do. A. Phéin tng qué man tire khéc “B- Phan eng déc té bao phy thudc khang thé . @ Phan tng qué man do phirc hgp min dich luu hanh ‘D. Phan eng qué man qua trung gian té bao £, Phan tng qué man mugn_ b.ste set it 64. Khang thé tham gia vao phan ng qua mn. type | a A IgA “& IgM — G IgG D. IgD EWE or the By mae TITUS mat A tiit B. 687 mi Be 333 ml D. Om E, 83,25 mi 66.Néng 46 Kali huyét khéng nh@ng phy thug vao téc dé dura Kali vao co thé va téc 46 thai trir ‘ma con phy thudc vao 1 yéu t6 quan trong [a A. Can bang xudt nhap nude (gitra co thé va méi trréng). 8. Sy phan bé dich gitra khu vye ndi mach va gian bao. “G- Sy chuyén dich Kali gifra ngi bao va ngoal bao, D. Sy chuyén dich Kali gitra ngi mach va gian bao. E. Su chuyén dich nuéc gifra ndi bao va ngoal bao 67. Nguy hiém cia gidm Natri huyét fa c6 thé dn aén A. Mat nude nhidu hon mat Natri B. Thodi héa myélin cau nao “G: Phi nao gay tang dp iirc ngi so D. Phi chi duéi E. Mat Natri nhidu hon mat nude 68. Trong didu kién binh thuréng, lugng dich mat chi yéu qua A Nuc tba B. Song tieu héa (phan) ©. Bay hoi qua da (md hoi) D. Buéng hd hdp E, Burdng chuyén hoa 69, Céc nguyén nhan sau day c6 thé gay ra nhi&m toan chuyén héa, NGOAI TRU. A Suy than. : B, Tiguduong. ©. Tiéuchay. “B- Non 6i kéo dai. E, Nhiém acid lactic 70. pH/méu binh thueng dao d6ng trong mét gidi han rét hep tir A 7,85-7,65 - B. 7,45-7,55. “G_7,35-7,45. D. 7,25-7,35. E, 7,18 -7,25peace | { a e s 12 71. Yéu t6 gitp phan logi nguyén nhan cia nblim-toan-chuyén-héa la A. Nbpg a6 dudng huyét +06 thdm thdu huyét trong C. Nong dO Jon F/ mau ©. Khoaing tring anion E. Ndng 86 bicarhondt 72. Cc co ché sau day sé din.dén nhiém toan chuyén héa NGOAI TRU ‘A. Mat dy trér kidm (tidu chy...) B. Tang sn xuAt acid khong bay hoi (nhi8m toan thé ketone...) 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