As , oe Seas re Bape Ewe Netter's Cardiology i # Marschall S. Runge E. Magnus Ohman cn Po iS Lea ees | Gre eee eeeae aL Netter's Cardiology [See Me eS re Ve cs ar aNd HRA John A. Craig Carlos A. G. Machado DPIC Ere comm STC MSCTECO) ASC (ero aT on Orne Cg aa Le ee 9 3 eer Mee sede TIE Je] Fie BSR EHR ESR E Eo eet Cae ee 9 8 pe Te SM a oh | cas ed i RR AAR Se SM SM Ld GAKLER BERNetter’s Cardiology Marschall S. Runge E, Magnus Obmen ISBN: 1-929007-05-1 Copyright © 2004 by Elsevier. Al rights reserved, Authorized Simplified Chinese translation from English language edition published by the Proprietor. ‘Copyright © 2007 by Elsevier (Singapore) Pte Lid. All rights reserved. Elsevier (Singapore) Pte Ltd. 3 Killiney Road {W08-01 Winsland House 1 Singapore 239519 Tek: (65) 6349-0200 Fax: (65) 6733-1817 First Published 2007 2007440 Printed in China by People’s Medical Publishing House under special arrangement with Elsevier (Singapore) Pie Ltd, This edition is authorized for sale in China only, excluding Hong Kong SAR and ‘Taiwan, Unauthorized export ofthis edition isa violation of the Copyright Act, Violation of this Law is ‘subject to Civil and Criminal Penalties. ARENDT Hi ARR TEAR ARRETElsevier (Singapore ) Pre Lid. E+E CRIMEA ETE ACMATAN AOA TOGMTRE LG) UM. RBZ, we WEAR, HAMAR. SEMA (CIP) Hae RAP OMERER OANA SEI. — ASB EAH GGL ,2007. 12 ISBN 978 ~7 ~ 117 ~08716 -2 1. eM a Mesa VAT He ASP CP C3 Be (2007) 98 068804 FR -01-2006.1708, OAS eS MA EWR ABST NRL RARER O10 ~67616688 ) ACRE ABT a 3 3 a 100078 itp: swe. pmph. com pp @ pmph. com 010 ~67605754 010 ~65264830 stoic ALE BABA 787 x1092 1/16 FO: 39.25 OT EF £2007 4 12 HUM LAE 2007 4 12 FET ARE cE + ISBN 978 ~7 117 08716 ~2/R + 8717 + 226,00 i RUILATAT, ALIN, FTA AEMARARABIS: 010 - 87613394 (SURLET'S LL A ALA) = s MARHWRMSTBREEH * He + Be SHSPHRSRER BETHeA HE MIELE Co PEI TO TANTEI BAG TG A A, CH LI BR Dore ARCH | AE ESE S20 HAAR ER PRIS IZ EIR. HAAS BEDS TRUE 9 A BB HEF TERI SRE AE A Aes LE Se AS FRA MAE EIFS SHIM YT FEE RE AE DENT SA APS HE EA TRA DIR Fi BB ABI AY PE IP SA A Ae HEATER PR TS EG A PPI SR ITE ESAS CS A DLE OB EFL, AAC RTE HT AG: RO BABA BF BR RENAE RTE RRR. TENG RB HE USER TT et Ei EME 96 A TER, AA BA BA 2003 4F ARDY HAL CARES BLED EMTS TBE DR PITT BS SL SE a LTT BH) AER ANT ie + Frank Netter 8:22:80 A5 th A) Be“F BL AZ — , HS SIR ASS 3S FRB AE Bc) eR TLE BE TOP BAIT ET ST IN DRE BEN DZS BR TER ES — BRAS OLED Co ECR, ELL AT Be AUST RA: BEE — ASSIA AS ARASH aie HG YL 9 I SSE PRENSA AE LEE PE Co A A A AC) TT EL PE AAT BE. RATT ARACEAE FY LL IAS BRE 5 ADR, PTA, ASP Pe BT PE ZOE NR, HERAT EB AVES AE Be BIR TEE ARR YY BE: aE Ae ID Se TTC AN AE BEA PES — SI A He BEA, EMAL SRL TR AVM Te AUR AS HAA Bi HH BOAR ET EME Be EA A, 5 BRAT TREN, EUR, MEA OM ACL 1 fos SET AA, F5Ae R EE T STE SAE EA DEAT EAI, en EI SRE ATT AIS FD HS SSE a HE TERR RUA — BE, SE ASAE DIEM, Netter AREA FEES. REHOBOTH BEA A OZ ASMA, Netter BBE ETE Esp RACE ASIA EY OTE Ae BLA, SAREE. A Netter SRS mL PB SURAT FE SEE, A, A SEALE. John A. Craig SHE, Crols A. G. 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BURT SUCHE: RIC, (LA EEE BELL BES ig EEN A) ES A, SAGEM, HFG HE Hr RGA HK FRC RM RE DBA PRE. Tae, DUBIIATT Le —s, ah, ET REHEBI ELIE Rte RR. LB 20 140 SO7E (UI, MARAT IE — — fi ot 25SEAR TA DEEL F12-6 LASS PF PRBS ARE SEF MSL STM AREAL Fai EXGADREPER PRE E LS BLE RE AMMAR WRELA. BLAS ssl 26 fi otFERRE 2 FLFR HDPE BB 1b Be EOE ee A. 1, RAP CET Hr AG T RUE, (LIE, WAT RAD AUR. BS, SSB AE ACER MLA RAE PANT FE WTA BA, TG EL Fh RE AL PAA A AEWA AL. deste bed C- BNE AREAL HR, 19s EE OR A HAR. BO, PERO Mh ER KS OAM HED sk RE. CT AI MRI Be ABC HPA BOATS. HRI, Eee ORL BREE CAPRA RITE AE — TA 2B, WRB Pi A he RT RE USE AT LAA ARENT IA. PST, SERMTFLUL, BMA ERA WE TORE Ae He EB, PEPE EY OTHE, FRET fe BUR 25 9 7 OG EE ANTE H « BAR Haber E Automatic detection and recording of cardiac arrhythmias. AMA 1959;170:1782~1785. Hollenberg M. Comparison of a quantitative treadmill exer- ‘ise score with standard electrocardiographic criteria in screening asymptomatic young men for coronary artery disease, N Engl j Med 1985;313:600-606. Lakatta EG. Ageassociated cardiovascular changes in health: Impact on cardiovascular disease in older persons. Heart Fail Rev 2002;7:29-49. Lefkowitz Rj, Willerson JT. Prospects for cardiovascular research. JAMA 2001;285:581-587. National Institutes of Health, National Heart, Lung, and Blood Institute Fact Book. 2000. Patterson C, MadamanchiN, Runge MS. The oxidative paradox: ‘Anather piece ofthe puzzle. Gc Res 200087:1074-1076, Ridker PM, Cushman M, Stampfer MI, Tracy RP, Hennekens CH. Inlammation,aspcin, and the isk of cardiovascular disease in ‘apparently healthy men. N Engl / Med 1997;336:973-979. Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 1993;362:801-809. 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BA ICAY NH, te Ay FAP OWL, BAMA: CEES BARU Hal YA 8 65 EAP, YY aA a oh Hak LAPD a WE FN YL EAR A A A ASME AUMIE RASA He BET MRT AAS WOAH AT AAU RE, BRT Hs ABU AR eR SAP ADAG Ib OT PA PAIS GAP NUR AEE CLE, BER Kim WY, Datias PG, Stuber M, et al, Coronary magnetic res ‘onance angiography forthe detection of coronary steno- sis. N Eng) Med 2001;345:1863~1869, Rumberger JA, Breen JF, Johnston DL. Magnetic resonance imaging and computed tomography of the heart and great vessels. In: Murphy IG, ed. Mayo Clinic Cardiology Review. New York: Lippincott, Williams & Wilkins 2000:743-769 Steiner RM. Radiology of the heart and great vessels, In: Braunwald , Zipes DP, Libby eds. Heart Disease: A Text book of Cardiovascular Disease. 6th ed. New York: Saur- ders; 2001:237-273. 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A report of the American Cok lege of Cardiology/American Heart Association Task 62 Force on practice guidelines (Committee on Coronary Angiography), Developed in collaboration with the Sock ety for Cardiac Angiography and Interventions. | Am Coll Cardio! 1999;33:1756-1824, Sheehan FH, Braunwald E, CannerP, et al: The effect of intra venous thrombolytic therapy on left ventricular function: A report on tissuetype plasminogen activator and strep- tokinase irom the Thrombolysis in Myocardial Infarction (TIMI Phase 1) tial. Circulation 1987;75:817-629, (Bae %)86 errant eH AL i — ARE Ws aE He OG BA MAT Le TA He FL ARR te US AE, BSA SEPRET RAS ERB REE eo CR AE BME A Hic PR NOE EBS DAS HAE AO tA A A Be MORAG BHEMAEZ FRE PRM RE ATING ALEL EA I PA AEA LAT PPP NE. EPR ABE AS LI EF FE FA, BE AG, BUR Le, VA Bert VOL. AE ULF FE OE BE J AT EM AE PF BHU A ET Or. PA Br Ae AEP BM FS LAS (A EPS SE ADL A PE BH HER, YY iA RDAE FLAS EEE EME IT tt EAD ReeE BORG. 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PAE ASA AY eT IRN Woke, Poi ee Be Ain PEA FE SETAE ABIL FEET TIERRA FEF ARS AA, EAR HE SR Ce kat aR I EE — AE ES 5 PES RFS HY GM SDA EAR IRE, PERERA BK SR A AD HEE A TSH EAR SHE PERI REE A ARNE (LIBS 2 RE) ML EE FN — MRE AT BA el ER FEY ESR Ay TG AS ee 8 EAR DRREISE HAO BEBE A Hit UR BRET AE AHL) (1 2 3S SS A WUE ITF ROR TP, HTT EL EE Sate LR Ja Ae EM PR AR IESE BELL TUE i 5 HAR, AAT AL BEE TAR PAE 3 A NE EAE RY AB A ARREARS AR AYR AAR SYA BEAD WB AE AE AD AULA a, 1 EAR a BER BB He EAE HG INE Ea EF A a) BA REET VE WA RATT a eT. HAS AE oC PBR AEA LL HL Al Hooter UTE BERATED, RY FARE AS 1 OTA T Et, SFA A a WEAN SS EAE RHE HERG AAT ER TERRA TE REY TERE (SLE IV BSP) FRIRT7 fal ASE REDHAT RPE A BE, SCAMS AE FAI Or LPR Li BEE RD CMU AIT AT AEE. FUNERALS WLS A EE SA SLL ES ALS LAT FEM R ETAT, UME IESE TE HI ARE DRAWS BAES ACE OEY AT HY WL WLAS FETE EE. Pe RAIL OE GE) BT OWENS. PET AT Pel LA Pa REAUARIN, FT (Ey ULE TE RY BS A, ARAM ET We HAT SBE LAAT, BURCH BL FF AMAT. 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WF H BSA Fees URE CIR A, BEST ATIF CABG ATLL. LAN 2G A De RTT Wh FE Be FE AT FEZ RD AL CABG (ED PUMA IAIT HFRS SEF A AP Sn IS a a A HE. LAD iE BR TEVL ePU TTR CEH LBL PEL IH ARE, TREAT 2 Be TEAR ADS AgBIE(PC) «YF FEL ERAGE AS FES AE BOTA HE ER PTA 8 aS UL PCH ARI ASP REIT | ARAL FPR CT. a EF A a 7 BT BK PA PSEA ALL ER BE HH IG RAE RENE NE RP ATT HB LET ARMM ARDS. FAY HMR SRRGE PERE DEAE MR i ORL LITA FERRE Ab. BREA vl PEE Oh SEE TAL TRS, FEME AeA bist AEP A BASE Py is ACHE EE ME CY UAB. SED REE, BOF ON TEE A BERR BAA REL EA Rep EZ OTR es Ze HO PIE ITT Ss 80 a obHERR SATAY REM ETL LATTA FAM = MLE A AF SAO RS SAAT HT AEE GNI BL ALR ATEETE AG. SLANT MAE ma. BAS Antithrombotic Tralsts Collaboration. Collaborative meta analysis of randomized trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BM) 2002;324:71-B6, Beta-Blocker Heart Attack Study Group. The beta-blocker heart attack tral. JAMA 1981;246:2073-2074, Flather MD, Yusuf S, Keber L, etal, Longsterm ACEnhibitor ‘therapy in patients with hear failure or left ventricular dys- function: A systematic overview of data from individual patients. Lancet 2000;355;1575-1581 ob HOPE investigators. Effects of an angiotensin-converting: enzyme inhibitor, ramipril on cardiovascular events in high-isk patients. N Eng] Med 2000;342:145-153. Meta-analysis of trials comparing betablockers, calcium antagonists, and nitrates for stable angina. JAMA 1999;281:1927-1936. Serruys PW, Unger F, Souza JE, et al. Comparison of coronary artery bypass surgery and stenting for the treatment of rmultivessel disease. N Eng! J Med 2001;344:1117-1124, ‘The SoS Investigators. Coronary artery bypass surgery ver- ‘us percutaneous coronary intervention with stent implantation in patients with multivessel coronary artery disease (the Stent or Surgery tral): A randomized con- trolled tal. Lancet 2002;360:965-970. ‘Yusuf $, Reddy S, Qunpuu §, Anand S. 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BRE HE AT See MOP I HE SHEE TES. Gh AMA At APR A REAR FATE, TAIT HE DE oe Me, HF Be HE — wb. BASIN Bertrand ME, Simoons MI Fox KAA, et al. Management of acute coronary syndromes: Acute coronary syndromes without persistent ST segment elevation. Recommenda- tions of the Task Force of the European Society of Cardi ‘ology. Eur Heart | 2000;21:1406-1432. Braunwald E, Antman E, Beasley J, et al. ACC/AHA guideline Update for the management of patients with unstable angi- ra and non-STsegment elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Com- rmittee on the Management of Patients with Unstable Angi a). 2002. Available at: http://mwwacc.org/ctinical/ guide: lines/unstable/unstable-pd Fuster V, Badimen L, Badimon |], Chesebro JH. The patho- ‘genesis of coronary artery disease and the acute coronary syndromes. N Eng! | Med 1992:326:242-250, 310-318. Libby P. Current concepts ofthe pathogenesis of acute coro- nary syndromes. Circulation 2001;104:365-372. Rauch U, Osende jl, Fuster V, Badimon |], Fayad 2, Chese- bro JH. Thrombus formation on atherosclerotic plaques: Pathogenesis and clinical consequences. Ann Int Med 2001;134:224-238, Yeghiazarians Y, Braunstein JB, Askari A, Stone PH. Unstable angina pectoris. N Engl Med 2000;342:101-114. (BR aR HE) 89SAE MAR IE( AMI) FRIES RRL fe ( HL) EA ANCHE AEE R GALA SL fodth HE, Lh, OMMARLAR MM DRSAR. RTH, HM CME eek Bs eRe SF 200059 A ART Bt MUIR IEA wR HO Hi F 3) HK HE Z —C AE 40 J Am Coll Cardio 2000;36 : 959-969 i AZ ) A EA Mic itt ak HEE Fee BREE IO LAE HET: 1) QDR FEI He pric IT A NUFF Be (on HLS BE), EEA FAN F6( 40 CK-MB), FE RELL F 8 > — 3a: Dib LSE 5 Co PA HE QE ATHESE, > Fes FRI 7T Hie a Ee ( ST BAHAR a FAIR), BATS RADI ATIF ANGER MK IEA ) 2) Sate LFEPA DR A — BY DA fs BA EL Ls LAE Bibi: 1) JPA be Ae AS HE PE QUE. 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SABER A IES OT BIE ZS a HEIBE SE YOURE, PY LAYOUT, ASR LAF A 28 So BE Se A AE DA AHR wyBRDRDIT AT a istry (ACCNCDR). | Am Coll Carol 2002;39:1096-1103, SERM Douglas JS, King SB Il. Percutaneous coronary intervention. In: Fuster V, Alexander RW, O'Rourke RA, eds. Hurst’s The ACC/AHA Guidelines for percutaneous coronary interven- ‘Heart. 10th ed. New York: McGraw-Hill; 2001:1437-1469. tion. | Arm Coll Cardio! 2001 37:2215-2239. Topol E Textbook of Interventional Cardiology. 31d ed. 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CUBIC AID SLO LI Rau TRE es oa HIST BARE Dunlap SH, Sueta CA, Tomasko L, Adams KF. Association of body mass, gender and race with hear failure primary due to hypertension. | Am Coll Cardio! 1999;34:16021608. Francis GS, Johnson TH, Ziesche S, Berg M, Boosals P, Cohn JIN. Marked spontaneous improvement in ojection frac. tion in patients with congestive heart failure, Am J Med 1990;89:303-307, (Goodwin JF Gordon H, Hollman A, etal Clinical aspects of cardiomyopathy. BM) 1961;1:69-73, Ikeda Y, Ross | Jz Models of diated cardiomyopathy in the ‘mouse and the hamster. Curr Opin Cardiol 2000;15:197-201. Pearson GD, Veille JC, Rahimtoola S, et al. Peripartum car- cdiomyopathy: National Heart, Lung, and Blood Institute and Office of Rare Diseases (National Institutes of Health) ‘workshop recommendations and review. JAMA 2000; 283:1183-1188. ‘Spector KS. Diabetic cardiomyopathy. Review. 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Revised eligibility recommendations ‘or competitive athletes with cardiovascular abnormali- ties. ACC 1994; 24:848-850. Stauffer JC, et al. Subzortic obstruction after sildenafil in a patient with HCM. N Engl | Med 1999: 341:700-701. Ten Berg, JM, Suttorp MJ, Knaepen Pj, et al. Hypertrophic obstructive cardiomyopathy: Inidal results and long term followup after morrow septal myectomy. Circulation 1994;90:1781 Zieman S}, Fortuin N}. Hypertrophic and restrictive cardiomy- ‘opathies in the elderly, Cardiol Clin 1999;17:159-172.. (#8 iF) wb A 129$1438 PR AEAEL eSDLIs SMILE DA ST RD ETE Bl fe PR, AR Is RATER HEA A ALTE) APIS He RS. MA Mls BL aE Bs RAT MNPHRAR, WDAAPRAMHAE LMPHRLLBMR, AARP ORGS RAE FAR BDA, AEB AR AEE ES RR i 20 vy UL Soe Hig TP ESF LA BR TOS, ROBE HE 1961 FE Fe BN SAEED UR, BT EIA, BI FRILL. ETO, ASK HED rei FA OTR, IRL EAE A LF, AUER KORE GR AT. +f, RAPA IY BR BL LA RAMA MLA ZERIT LF He PR al AL La AS PEM A 14-1). LEP HEME, PPR AE RS FLD WL, CABELAS, COLIC ASAT eI AMER. 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Se PS AM BR, EMT SR aI RIE oh, HOR SAUL ai WIEN, SAE MA SU TAT AR BO ARTESIA. SARE ay REE MP FHS TEA BOR ALA SH. ALON GLI a SHO BE TE a 1 A PFT PF hs a ab RPT HE toe MRI AERC HITS TB MBAR Rede, BT an TAT ADE. MRT AY DIS Hl) ALIA LSE BA, AT ECE HE A SRA BLA AR AP EE HE HH SEE Wisi. ERATE Hy RAMA, (EU AA ARCO Hl Ls I RFR HT BRIER I Wi, ADC HEIAYT LISTER ATIVE. kA EGG Ae AT ee Reo, MDE RD PE EEA WRITE uk. BAH ‘Asher CR, Klein AL, Diastolic heart failure: Restrictive car diomyopathy, constrictive pericarditis, and cardiac tam- ponade: Clinical and echocardiographic evaluation. Car- dio! Rev 2002;10:218-229, Frank H, Globits S. Magnetic resonance imaging evaluation ‘of myocardial and pericardial disease. J Magn Reson Imag- jing 1999;10:617-626. Klein AL, Scalia GM. Disease of the pericardium, restrictive cardiomyopathy and diastolic dysfunction. In: Topol E}, ed. Comprehensive Cardiovascular Medicine. Philadel phia: Lippincott Raven; 1998:669-716. Kushwaha $8, Fallon JT, Fuster V. Restrictive cardiomyopa- thy. N Engl | Med 1997;336:267-276. Nishimura RA. Constrictive pericarditis in the modern era: A diagnostic dilerima. Heart 2001;86:619-623. Palka P, Lange A, Donnelly JE, Nihoyannopouls P. Differen: tiation between restrictive cardiomyopathy and constric: tive pericarditis by early diastolic doppler myocardial velocity gradient at the posterior wall, Circulation 2000;102:655-662. Spodick DH. Combined restictive cardiomyopathy and constrictive pericarditis. Circulation 1996;93:616. Spodick DH. Restrictive cardiomyopathy. N Engl | Med 1997;336:1917-1918 (RES HB) 143815% Bere WLI RAT SMBH RL EBREPCMAY HRM AAO AAHRRBA. COAG CM AXHRRERLR, KMPARAM RARE AAA T BAF Hs NEM BI EAR DR Roe R BALA ie mh Hs MMA, PRD AR / RA TSE Ae PRG SEH ES CAPS AIM STR, AE ASE aA A, ZENSERW TOMAS RAFAH OMB, DWN TARA IES AL, DIVERS MENG A WIR SY Hd 51H I (DCM ) HEF). AVL HM) PR i 261-0 AL. BOVE RV) ARH ALD WL AE Wap ASC. LEC AILIAG) 45 — 5 UG AB ERE A YH TA AS, BA EB HA, A — a AE Waite. 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WI EIS BERL WA E— ABA WT TIS AE, DETER ETE Bae ih fle A TS FL AE TE I GilFS B SLARBEH AUNTIE. A, IE AE IF EA) RL, ats A CR AE EC SUPA Cs Jy EM EE ) TE Bk A wh AVE LAS FC IFES —_— 150 a ALTEED ALG SEM Arbustini E, Morbini P, Pilotto A. Familial dilated cardiomy: ‘opathy: From clinical presentation to molecular genetics. Eur Heart ) 2000; 21:1825-1832. rispell KA, Hanson EL, Coates K, etal. Periodic rescreening, isindicated for family members at risk of developing tamil ial dllated carchomyopathy. J Am Coll Cardiol 2002;39: 1503-1507, Davies, MJ. The cardiomyopathies: An overview. Heart 2000583:469-474. Franz WM, Maller O), Katus HA. Cardiomyopathies: From enctics to the prospect of treatment. Lancet 2001; 358:1627-1637. Kamisago M, Sharma SD, DePalma SR, et al. Mutations in sarcomere protein genes as a cause of dilated cardiomy- ‘pathy. N Eng! | Med 2000;343:1688-1696. Lowes BD, Gilbert EM, Abraham WT, et al. Myocardial gene expression in dilated cardiomyopathy treated with beta blocking agents. N Engl ! Med 2002;346:1357~1365. Maisch B, Ristic AD, Hufnagel G, et al, Dilated cardiomy- Opathies as a cause of congestive hear! failure. Herz 2002}27:113-134, Towbin, JA, Bowles NE. The failing heart. Nature 2002;415:227-233. (Fig) ay AL 8 1S10% WLR MMB WL ARE, HAT AR RM i fe KF RR, KRHA T HERR HA PH TEAM DURGA ARR, CMR A MRR HS MSH, KRDEAAMA—A BAR BRE CRGMELTUAARRAY BK ARAL, KGL ARELAS, RPA GT RRS BABE, WR, REEIODF EDO PEREEA LT RHI HEM FoF RBS MB HE ARRA RCARBMT, AFFRPCMAPRBELS ARREST GREAT ORS RTEA GBR, RAMA PEACZE AUCH, ALP ABB IY WS OA FEL FRE. 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GS AL WL TES WLI EAT EBS SE I Mit, PT AH AE A SPUD BEE BT HEAT a TL A Fy BESS SPE IW TAFT EAE EE, Wi EL PEN IF AY RENT Ls WLR HE HED TK RTA. TARE LL ARERR HE PE AAT A Me Ha BEA BEATE BE. IL PRE ZEN MSE E, — TA WAS ALN a Sa PE AF A oH RE AEA EERE IBM A fA BE BRT. MORE Fanta Be HIER HF ZEB HE ANF BOI AD REN, ANT AEA NL, (FEAT SE ATES Ae PWIA RET IATT, 45 IR HM AIM, IER ASEH OT EL yi RATA IT FB BARR fetiman AM, McNamara, Myocarditis N Eng | Med 3000383 1388-1398 Gullastad L, Halfdan A, Field J, et al. Immunomodulating therapy with intravenous immunoglobulin in patients with Gon hear ae, Creuton 2001;103200-225 Lage Sein iene or a ese N ng Med 1994380 1129-1195, Liv PP, Mason JW. Advances in the understanding of inyocar Cevaton 0011081076082. Mason I, © Conel 8, Herstowitz etal Acne wa of mmnosippressve therapy for myocar. N El Med 1995338269275 McNamara D, Holubkov R, Starling RC, et al. Controlled trial ieee pi ain esate carlomyopay. Cree 200103:254-2259. ©rGaneh 8, rho DG. 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ACC/AHA guidelines Prospective Trial of Intravenous Milrinone for Exacerba forthe evaluation and management of chronic heat fat tions of Chronic Heart Faliure (OPTIMECHF) Investig: ure inthe adult, Circulation 2001;104:2996~3007 tors, Shorter, intravenous milrinone for acute exacer-_www.americanheart.org bations of chronic hear failure: Arandomized controlled Sueta CA, Chowdhury M, Boccuzz SI, etal. Analysis ofthe tial JAMA 2002;207:1541-1547 ‘degree of undertreatment of hypestpidemia and conges- Heart Failure Society of America. HESA guidelines for man- tive hear allure secondary to coronary artery disease. aganart fet wher fare used by fis Am) Cal 99985 1209-1307. tricular systolic dysfunctionPharmacologic approaches. 1 Cardiac Failure 1999;5:357-382. wwwhisa.org, (FER RMR F) 166 ots BL i818m UES HEL SERABRMABRALS AMER RA THE, ROR RM AR. 19618, Shumway 4 Lower RAT AA FONE LM LE MAT ARMY LRG MLS RBM A AB HLS BOS 5 HER HAE T BA. 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OB BPR PETE BE 5, ARESE I ) ASE SE PR — FYB HEA, BORLA EEE FRA RPA INL CS EAA, (CEL — TESS BE AEA TTT GU TATT = FER FHS Hd OLA EAR ET HEIL AS A, FP PE SEAS TT RAAF ESHA FAL A WBE Whe PEER RAG Ir EAS, PI AULA SIM, BI AEE PE ARH AE TT ASHES, Be BS DEFRA AZ ERAS ADEE PEAY AEB, CAR FEMS RR PLB. FF AE EAE BY EAM ad PAHS I A BS IME I, EL a Se AP A BS AL HEME MEA, JRE AE DE Le SA AL EL SATE EMT RA Ta, Fe PRHE i> Saxe SPIRE. ARR CHER DL AE HS A HE SZ “AAC HOPE. MURAI SET Hk BEAM NATE, SOWA ESS UT He AEE SE AARC FT HED eI HET RSLS a A A ae, I Ps AR FAL 9 AE a LA AS VAD SEALER AT AER TEF BP BRAY AAT PRBS RRM HA TG MLR FR TREE ET AAC IM IN DG BE ls LA ALAS TA Ps OE PELE Be HRS FESARA ANE SAAR TE Fo A BEE. HP Re Ae LE, ER ESE AL Us LPG Ss ASEAN PTI, ASHES eH Mie. BAI Baumgartner WA, Reitz BA, Achuff SC, eds. Heart and Hear Lung Transplantation. Philadelphia: W.B. Saunders; 1990. Billingham ME, Cary NRB, Hammond ME, et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart Rejection Study Group. ) Heart Transplant 1990;9:587, Hertz, Ml, Taylor DO, Trulock EP, et al. The Registry of the Intemational Society for Heart and Lung Transplantation: Nineteenth Official Report 2002. | Heart Lung Transplant 2002;21:950-970. Hood KA, Zarembski OG. Mycophenolate mofett:A unique immunosuppressive agent. Am J Health Syst Pharm 1997;54:205. Kelly PA, Burckart Gl, Venkatarmanan R. Tacrolimuls: A new immunosuppressive agent. Am | Health Syst Pharm 1995;52:1521. Shumway SJ, Shumway NE, eds, Thoracic Transplantation, ‘Cambridge, Mass: Blackwell Science; 1995. Stuart FP, Abecassis MM, Kauiman DB. 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BH AN ET BF BBY 2 TE PEE SE HB eA (azimilide )J& FRB TORZG WD, HBT, FAMED Oke. ARS MATTE EMRE, fn SAS PRIN FD SSL ys ROL ( SE FAI HE FR ESE EL ASAE ) BT 1 Pa F Be ; Ey BE Sh ARTE HK A IRATE BEALL AT HEA, EARLE BITE LATO ARSE LEED abs, PAB LASSE LARA, ANAT EE THAR AES OTE, AEB Fey EE MUA. HP HMAC HE Me FAS I AE BEKK, SEITE SOSA DET ME ERA IRE — PAR AIS LA ADE FF EL, PAM RA RE BFP, (EL a i a HSS BERENS MRT SEER. BSI Arial Fibrilation investigators. Risk factors for stroke and ‘efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled tials, Arch Inter Med 1994;154:1449-1457. Fitzpatrick AP, Kourouyan HD, Siu A, etal. Quality of ife and outcomes after radiofrequency Hisbundle catheter abla- tion and permanent pacemaker implantation: Impact of treatment in paroxysmal and established alrial fibrillation. ‘Am Heart 1996;131:499-507, Fuster V, Ryden LE, Asinger RW, et al ACC/AHA/ESC guide- lines for the management of patients with atrial fibrilla- tion: Executive summary. 4 report of the American Cok lege of Cardiology/Ametican Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to develop guidelines for the management of pationts with atrial fibrillation). Developed in collaboration with the North American Society of Pacing and Electrophysiology. Eur Heart J 2001;22:1852-1923. Haissaguerre M, Jais P, Shah DC, et al. Spontaneous initia tion of atria ibrilation by ectopic beats originating in the pulmonary veins. N Engl Med 1998;339:659-666. Klein AL, Grimm RA, Murray RD, etal, for the Assessment of Cardioversion Using Transesophageal Echocardiography Investigators. Use of transesophageal echocardiography to guide cardioversion in patients with arial fibrillation. Nv Engl | Med 2001;344:1411-1420. Kober L, Bloch Thomsen PE, Moller M, et al. Effect of dofetilide in patients with recent myocardial infarction and leftventricular dysfunction: A randomised tial Lancet 2000;356:2052-2058. ‘Sheahan RG. Left atrial thrombus, transtent ischemic attack, ‘and atrial fibilation: Does left atrial thrombus predict? Does absence protect? Am Heart | 2003;145:582-585. ‘Wyse DG, Waldo AL, DiMarco JP, etal, forthe Atrial Fibri- lation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators. A comparison of rate control and rhythm control in patients with atal fibrillation. IV Eng! J Med 2002;347:1825-1833. 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(HL, A EAR PA AY PVC IN REDETT RIM, FA, 3X A — fea ARG BBG VTE — AE AR a. SEA TR (ERI AR IS RTT SEL LAE HBT wh A> ACG BAST RC. 09 RE EARL VT GSE ACA BEE 9 LE HE WU THELEN Rote. Tike thei aT fie Jk eee fr TM TL, AEB OT AS LEAN REPUTE. FARRER ANDERE BE VT ARORA Oh, PA “AY” Co ULAR IRTP AE BOL A AEA. Sil, Bit AEA AT DE BERG AAT BE AT EB BURR ATT PARENT BAM The Antiarrhythmics versus. Implantable Defibrillators (AVID) Investigators. A comparison of antiarthythmic ‘deug therapy with implantable defibrillators in patients resuscitated from nearfatal ventricular arrhythmias. N Engl | Med 1997;337:1576-1583. Bardy G. Sudden cardiac death in Heart Failure Tial (SCD- —— 194 BRBeeb eaie HeF?. Late Breaking Clinical Trials, American College of Cardiology 2004. Boutitie F Boissel }P, Connolly Sj et al, and the EMIAT and CAMIAT Investigators. Amiodarone Interaction with Be blockers: Analysis of the merged EMIAT (European ‘Myocardial Infarct Amiodarone Trial) and CAMIAT (Cana: dian Amiodarone Myocardial Infarction Trial) databases. Girculation 1999;99:2268-2275, Buxton AE, Lee KL, Fisher JD, et al. A randomized study of the prevention of sudden death in patients with coronary artery disease. Multicenter Unsustained Tachycardia Til Investizators. N Eng! / Med 1999;341:1882-1890, Maron BJ, Shen WE, Link MS, etal. Efieacy of implantable cardioverterlefibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy. N’ Engl | Med 2000;342:365-373, ‘Moss Al, Hall W), Cannom DS, et al, for the Multicenter ‘Automatic Defibrillator Implantation Trial Investigators. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia, N Eng! | Med 1996;335:1933-1940. ‘Moss A), Zareba W, Hall WI, ct al. 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BALEARES LNAI TS AC She TF BIRRIECEM AK AMAT HUTT RAE BEA VE D, CLARE Me 9 EFL Bk oe TT PREGA. BEARDS FHT BO2501, PUD ERE I SERRA, IR Fei 2 FEMALE ERAT NH APT AHS KA BM EAB, FT ik FE FEAR AAG UL. ae PELE 1 5-38 £8, AC ANCA sl AU AT WA Bede — 5 A, AE BL es AHA. RRA AUREAR ATL BB AIT — EE HOES Ae 8 La ER AE PE REAR AY BL. BAY Ash ARH, (SEN A A EA AREARAEAR 76 FA. Hh, ALE AE PE SUEAT OC BR 5 ET BE OHA, HEE ETO SRB SP Ta] A ES 26 EEN SN. le ADMIN AIRED) JS 2a IE A LTE EE RZ. BAIR Devinsky O. Bradyeardia and asystole indiced by partial seizures: A case report and literature review. Neurology 1997;48:1712-1714, Gregoratos G, Abrams J, Epstein AE, etal, ACC/AHA/NASPE 2002 guideline update for implantation of cardiac pace- ‘makers and antiarchythmia devices: Summary article. A. report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pace. —_—_ RR 203REM S ‘maker Guidelines). 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MRI AT Pi wR a PEE AL SA ( ILS 20H ) FEAR SY AKU IS. ADE, MRI FY FE CERES EL ALI 09 2 SE TEE. HARTI FE Se Sue A a), I A SORA ZIRE. PRR RTT OMEN, 1 ML 2 AE, PAL ACS FAS AE ME a SU te Ae. FB ALA SUR IE Te Ae MIE MTA, FY PER BIEBER. WME INTRER A, PDR IS TF 2 eC fl EAP EVRY A SCORER TRAE. EH AFR ioe AT Ee AG fi Tt Sa A PK MRT AOA INTE. LA SCORER 1c AB AES, 7H I SR Be MIB PEA RE RY HEE RPE Fi Brugada le HERI, MAT KE Brugada 2 Er TE BR A HO BR HEE 12K PA 10mee kg, OSD Sh kif se. mY ECG TEA A A —_—_—_— BR 207ORES RE H, VAM BR) V2 BICRR) Vs PER AE AE SEEN, LTH AORTA AT 2mm HF, AA BATES. TEAS AEE aT (AEH Ee He AAG (Ht QT TAL IOT RE), Fa 3 BU PRE FN HEB PSL RE YE TITAN. CHAK 22-2 HH T BBW, 22-1, PA 22-2 7G TSMR. RA SC AL ABE hi APE BETES) FE LE AE HERI. TH AY AE ASAE, Hy BT PE EAR i. AEE A PALA TT UI UA AE ASE IE, LF HUT NAL. WR SE Ae HM BR AE WE), MP LATE. R222 BRAVE ASS Se Ae Sea Mess it OI ask CAFE BS A + Sea REA: AT LCF A HLA ob LIE. 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MATERA A EBT OL, HT, 208 REERR 22-1 DEH: 4 A IT EI -[=} TERRE -{z} Ed ar RRS 209RES Fa] 22-2 EDR: A REMIT RA Pease eta ete ee ee Te ele hy py cp ef le gi FRERBENTOBRES. toes EBS ATRIA AEST PRA IEL PRS RL $0591. 238 Bite ae AVM BALEAAL SAR SENE GOES PRs, TREK Sere am e 180: 135 90 te eo 0 AUMA RRA. Ba ER RE 1802 AUMARRES ME. DRIER Holter #3 ESR UP Gy He RB TE 8 atte Es aS: MAT AT (RE: GATHMKA OSA, soe RM ew 210 ARRE BK REST —ARLATIMHT 8 Ao ART fA EAS WC AIR PS Af BEF, Ha FL SE PETRA J) «RP AE fie PE HD AGS WAFL. WIR AER. SRA THUAE SA RD HE, A EAT EB TE IT BAYA RR Rete. ABE DE SEA TEENY, FF BARE A IN HE We, BAP RSE ME, FE DE AEST. PERE SCAG. AE RSS a EP EE mY AE BRS SETS SR AYSA MAD IE AS INE TAFE TB R. BAH Sheahan RG, Syncope and arthythmias: Role ofthe electro- physiology study. Am / Med Sci 2001:322:37-43, Sotenades £5, Evans JC, Larson MG, et al Incidence and prognosis of syncope. N Engl Med 2002;347:878-885. Wilde AM, Antzelevitch C, Borggrefe M, et al. Proposed diagnostic criteria for the Brugada syndrome: Consensus Report. Circulation 2002:106:2514-2519 (BR ae HF) RRS 2118238 LRP <2 UBRUEL SCD JR SLA RAS A a LO RGR. RA SUE SCD 8] 494 30 77 ~45 7. SCD #594 B & Ab FH A231), BO% VAL BETES AER IE SRAM AI GR Bs MAR he HAG ALLA AR AR, JE RO JR 85 BY LAE 20S DAC AP HK ADS RS RAs a BRIE A SL) oS A EI RARECEM, & Hos MUIR IE MIDE 4] RATS EAR AH OL, 5 tp RATES, LSA EH OMA 404 RM ICS PE HEF). 23-1 RA + LV RE SE Brugada Siete HQT ERATE ETE DEE LEAS 3% (commotio cordis ) + LV Dif MIEN, EPEAT FEAR GES AO 2, SEAR ALIK EAE ERD IEE LV Sf SAME Late CURE FFAS FA PH a 8) BhelEL MI (HSE) FRA Je SURE RA HE FFE, Wolff-Parkinson-White {IE DALE HR Chagas CML BA FoR ME AL AEG 1H PUI E ah aE. Fh AKANE Bbstein RAE. 6 HEA TE AHR fi CNET, AMR tl SP SCSCD (1) FB HE As LAK PF SB 212 BS Fe HE NE RCV), SU eB (VF), SEC EF 23-1). 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BAH IR, Zee VEIVT RH, 147 SCD HNfEPR. AVALA ICD. B SZ AA BA Bie RF SC Ey 1 Dy Ra HE, AYP FE MM oss EN BI Fa TES RESE «ly F] BE MAE SEE HEA EE HOLT OIE DP, ERAN 40% (735 FY 28% ) AL FREE IB A B EPR TAIT, FESCD RAMAN. BRUM ‘CBU FAL B SECA BA PAPAL AS Zo LDL. — EAE TEP BBS, ALF EB PRR, FUL UREFE TAY 22: BD 139%, SAT BARAT, TRAIN. WML BEPC EDR AGT Fe AVI SAC ty Ee PRR AS ORE NTS SAT BAR, LUTE A FA B AEP BEL Mi Ta il Me ak AB A] fe SCD Be A WEAR 619%. ART A TOT FE Ey 1 PA SC 6, BoD, a A ws eA A ti de, SG TH Tie BER SCD BA A F109 HATH. MARR HLS SCD HK OTA, CHR 2b FFE BR AE HE SPA AL CE ryanodine ZENE, 47 ABHY 2, —2E AEE FRM RR HE Ue Sa FE MR OAR AS, Be ‘eat ASE oS FE ETA —_—_—_ RE 219REE ARTA V 99625 ), (25 4e4= SCD Hes faiTA KK. ATE NE C LAE AA JS (CET. BSR AK Bt Na,K-ATP 1 A PRU RA IB Le HR By ARF FG AT BAHAR IL WL RH AVE SCD fH FE We Sm, Td SS FS PR 5 ALS BOREAS. MART BSE MS FARR AaB tH — 3 OME, (RS OSE HUTIDEHEROESE. AUEBESD AEA: SCD MATE AR SHB IA EE SCD NTT IE BERL, HEAT BUSA — AD GE 5 OA IS AANA AR, BUBAIT iF ML AE PERI SAGE PT FRAC E> SCD £9 EAE 5 BAR ‘AbKhatib SM, Granger CB, Huang Y, et al. Sustained ventric: lar arthythmias among patients with acute coranary syr- dromes with no SFsegment elevation: Incidence, predic- tors, and outcomes. Circulation 2002;106:309-312, ‘Angelina P, Velasco JA, Flamm S. Coronary anomalies: Inck- 220 dence, pathophysiology, and clinical relevance. Crcula- tion 2002;105:2449-2454. Bardy G. Sudden Cardiac Death in the Heart Failure Trial (SCD-HeFT). Late Breaking Clinical Tals, American Col- lege of Cardiology 2004, BoulitieF,Boisset |P, Connolly}, et al. Amiodarone interac- tion with beta-blockers: Analysis of the merged EMIAT (European Myocardial Infarct Amiodarone Trial) and CAMIAT (Canacian Amiodarone Myocardial Infarction ‘ial databases. The EMIAT and CAMIAT Investigators Gireulation 1999;99:2268-2275, Drugs that cause torsades de pointes: htt//www. ‘atdrugs.org/medical-pros/drugliste/drugzlist htm, Huikuri HV, Castellanos A, Myerburg R]. Sudden cardiac death due to cardiac arthythmias. N Engl J Med 2001;345:1473-1482. Maron 8}, Gohman TE, Kyle $B, Estes NAM, Link MS, Clini ‘cal profile and spectrum of commotio cordis. JAMA, 2002;287:1142-1146. LUretsky BF, Sheahan RG. Primary prevention of sudden car- diac death in heart failure: will the solution be shocking? | ‘Am Coll Cardiol 1997;30:1589-1597, Vincent GM, Timothy K. Zhang L. Congenital long QT syn- drome. Chin Electrophysiol Rev 2002;6:57-60. Wilde AM, Antzelevitch C, Borggrefe M, et al. Proposed agnostic criteria for the Brugada syndrome. 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AS EAS ADSI UMAR TENA, HE BESE AP Bk BU SR PE, CARR FT LA CEFF ao SBT SHEAR A SS eA SL FE HERE. aethbohitt AFB ALC EE, BTA HAAS Be A, ZN AT VI Pe a See 2 ENT AYR. PAT IQRS eb Bat we, WIR RE AEE S SHE A WILE ML SE, BERS PARRA PRATT. AH ES PE, AAS ERATE SE ORS HeLa ae Ie SEW DES LEM RD MBE. FAA AA HORE QRS BEL BHTLIA, MALES FAA. MAB TAA, SE DNR AML, CREM. BR 5 TI Fe SIF FE QRS te aA, We EBA SEO) 5 REBATE AAT HC AREF, BED BAP AIR MLE. ELAR, Rae BF: FEN BES, MURR A SIA, AT AS PARA PRET. CE AMON Ae, ALE EH SL ML BAP ANG IE. 5 LED RI He. SPREE R A, TORR ZA TTA BRB LA ID AIT. 50% LE PAR HEL ARE RELA RB ME BAIA A THERE SEROMA OATT «EPRI AE SS 1S PE LA a AR He PB WARE BO UR. RH SB, HEPA HEE FETE, ALLA RE RHE ICD HLA. ICD A Sit SBS FR SAF HAS a A ‘@Al( #5 A 200mg). D> BURA LERLA ICD Ji 24 i, BD SETA AHL" RR” 5 SUE MTSE TA DAR Be Bas P(E A he BH AWA AE), TART AG YE 9 LP BE ke RR, AGH ML HAMA. Bw, ICD Sit ECHEC EL, PA BERR HK B SEBEL HOTA Feta CMe SH CH AH th, CURIRAI AL B SZABO. ARAB BEE SE PURITY, LAR HR TRE PGTT OLD Soa. ate SEVEN LIA ORAM FELTED AA HIRE, BSS MLHE TA AUG RFD AOR. DBA 227RELDBARHAwIE AP ABSP ARR MY AES AIT I BS ARSE FAP 28 1 8 EHEC A De HOR EH: Bt AB AUAE Hy Ly DEH Js D5 Eb BH 8) PREG By FE BPE T PARE. A TATA FEAF ERG OLRM BE, MET ARICA 2S MEAT ED TIT FA. Bll HPT AEA HY AN EI HET HE BRT DAK HAD. BAIR Gredner SC, Klingenheben T, Mauss O, et al. Electrical storm in patients with transvenous implantable cardioverter. defibrillators: Incidence, management and prognostic implications. j Am Coll Cardiol 1998;32:1909-1915, Epstein AE, Ellenbogen KA, Kirk KA, etal Clinical character istics and outcome of patients with high defbellation thresholds. Circulation 1992;86:1206-1216, Ganz U, Friedman PL, Supraveniricular tachycardia. Engl | Med 1995;332:162-173. Jackman WM, Beakman KJ, McClelland |H, et al. Treatment of supraventricular tachycardia due to atrioventricular nodal reentry by radiofrequency catheter ablation of slow pathway. N Engl | Med 1992:327:313-318. ‘Masood A. Clinical spectrum of ventricular tachycardia. Cir ‘ulation 1990;82:1561~1572, Members of the Sian Gambit, New approaches to antiar- rhythmic therapy: I. Emerging therapeutic applications of the cell biology of cardiac arrhythmias. Circulation 2001;104:2865-2873. Prystowsky EN. Diagnosis and management of the preexc tation syndromes. Curr Probl Cardiol 1988;13:225-310, ‘Saksena S, PoczobuttJohanos M, Castle LW, etal. Long-term multicenter experience with a second-generation implantable pacemaker-defibilator in patients with ‘malignant ventricular tachyarrhythmias. Am Coll Cardiol 1992;19:490-499, (Pk te HE) RAEBR #2 LPEATSE PED RTE SS ak BEE AIAN RECA Di Hh HL AE T AAG IF as had oR Oy me, 1986 RECA AMAR ERA CEST ARERBE LBC HP PRRS RS HMA VIBE. 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BCE TE AE LA A ME ET HEME, FETE IG AES BLM LS LAE PEE PEE AEP EA AE RF 1 (B 25-1). RRA EDR NS HERI HE NS FOE FRUEBAR TG Be. RM BOR ROR HEL, Ee PERNT ADELA BSP RET Hy i BSH AS HERE CLLR RCA Wy AR SES PH BURTT AT. AR TT HET VAISALA VT ST BRIT AR FT EAT Hs. BAX Jackman WM, Beckman kj, McClelland JH, et al Treatment ‘of supraventricular tachycardia due to atrioventricular ‘nodal reentry, by radiofrequency catheter ablation of slow pathway conduction, N Eng! / Med 1992;327313-318. Jackman WM, WangXZ, Friday Ki, et al Catheter ablation of accessory atrioventricular pathways (Wolft-Parkinson- White syndrome) by radiofrequency current. N Eng! J Med 1991;324:1605-1611, Jais P, Haisseguerre M, Shah DC, etal. A focal source of at al fbrilation treated by eiscrete radiofrequency ablation, (Girculation 199795:572-576. Klein LS, Shih HT, Hackett FK, Zipes DP, Wiles WM. Radiofrequency catheter ablation of ventricular tachycar dian patients without structural heart disease. Circulation 1992;85:1666-1674 Morady F; Harvey M, Kalbfleisch SJ, ebAtassi R, Calkins H, Langbers JJ. Radiofrequency catheter ablation of ventric 236 RR