Drug Name Dosage Mechanism of Indication Contraindication Side/ Adverse Nursing Responsibilities

and Action Effect

Frequency
Generic Produce Inflammatory Contraindicated EENT:tinnitus.G ● Pain: Assess pain and
Name: analgesia and disorders in: I: limitation of movement;
reduce including: Hypersensitivity note type, location, and
aspirin inflammation Rheumatoid to aspirin or other GI: intensity before and at
and fever by arthritis, salicylates; Cross- bleeding,dyspep the peak
Brand Name: inhibiting the Osteoarthritis. sensitivity with sia, epigastric (seeTime/ActionProfile)
Acetylsalicylic production of Mild to other NSAIDs distress, after administration.
acid, Acuprin, prostaglandins moderate pain. may exist (less nausea,
ASA, Asaphen, . Decreases Fever. with non aspirin abdominal ● Fever :Assess fever
Aspergum, platelet Prophylaxis of salicylates); pain,anorexia,he and note associated
Aspir-Low, aggregation. transient Bleeding patotoxicity,vom signs(diaphoresis,
Aspirtab, Therapeutic ischemic attacks disorders iting. tachycardia, malaise,
Easprin, Effects: and MI. orthrombocytope chills).
Ecotrin, Analgesia. Unlabeled Use: nia; Pedi: May HEMA: anemia,
Empirin, Reduction of Adjunctive increase risk of hemolysis. ●Monitor serums
Entrophen, inflammation. treatment of Reye’s syndrome Derm: rash, alicylate levels
Halfprin, Reduction of Kawasaki in children or urticaria. periodically with
Healthprin, fever. disease. adolescents with prolonged high-dose
Lowprin, Decreased viral infections. MISC: allergic therapy to determine
Norwich incidence of reactions dose, safety, and
Aspirin, transient is including efficacy, especially in
Novasen chemic attacks anaphylaxis and children with Kawasaki
and MI. laryngeal disease.
Classification edema.
:
Therapeutic:an
tipyretics, non
opioid
analgesics
Pharmacologic:
salicylates
 Drug Name Dosage Mechanism of Indication Contraindication Side/ Adverse Nursing Responsibilities
and Action Effect
Frequency
Generic Blocks the Alone or with Contraindicated CNS: dizziness, ●Assess BP (lying,
Name: vaso other agents in in: fatigue, sitting, standing) and
constrictor and the Hypersensitivity; headache. pulse frequently during
candesartan aldosterone- management of Bilateral renal initial dose adjustment
secreting hypertension. artery stenosis; CV: and periodically during
Brand Name: effects of Treatment of Concurrent use hypotension, therapy. Notify
angiotensin II heart failure in with aliskiren in chest pain, healthcare professional
Atacand at various patients with left patients with edema. of significant changes.
receptor sites, ventricular diabetes or
Classification including systolic moderate-to- GI: abdominal ●Monitor frequency of
: vascular dysfunction severe renal pain, diarrhea, prescription refills to
Therapeutic: smooth muscle (ejection impairment. nausea. determine compliance.
Antihypertensiv and the fraction 40%) Severe hepatic
es adrenal (can be used impairment; OB: GU: impaired ●Assess patients for
Pharmacologic: glands. with an ACE Can cause injury renal function. signs of angioedema
Angiotensin II Therapeutic inhibitor and or death of fetus (dyspnea, facial
receptor Effects: beta-blocker). – if pregnancy MS: arthralgia, swelling). May rarely
antagonists Lowering of BP occurs, backpain. cause angioedema.
inpatients with discontinue
hypertension. immediately; MISC: ●HF: Monitor daily
Reduced Lactation: angioedema. weight and assess
cardiovascular Discontinue drug patient routinely for
death and or use formula. resolution of fluid
heart-failure- overload (peripheral
related edema, rales /crackles,
hospitalization dyspnea, weight gain,
s in patients jugular venous
with heart distention).
failure
 Drug Name Dosage Mechanism of Indication Contraindication Side/ Adverse Nursing Responsibilities
and Action Effect
Frequency
Generic Name: Binds to mu- used to treat Hypersensitivity; CNS: seizures, ●Assess BP and
opioid moderate to Cross-sensitivity dizziness, respiratory rate before
tramadol receptors. severe pain in with opioids may headache, and periodically during
Inhibits adults. occur; Patients somnolence, administration.
reuptake of who are acutely anxiety,stimulati Respiratory depression
Brand Name: serotonin and intoxicated with on,confusion, has not occurred with
norepinephrine alcohol,sedatives/ coordination recommended doses.
Conzip, in the CNS hypnotics,centrall disturbance,
Durela,Tridural y acting euphoria, ● Assess bowel function
, Ultram, analgesics,opioida malaise, routinely. Prevention of
Ultram ER nalgesics,orpsych nervousness, constipation should be
otropicagents;Pati sleep disorder, instituted with increased
Classification: entswhoarephysic weakness. intake of fluids and bulk
ally dependent on and with laxative to
Therapeutic: opioid analgesics EENT: visual minimize constipating
Analgesics (may precipitate disturbances. effects.
(Centrally withdrawal)
acting) CV:
vasodilation. ●Assess previous
Pregnancy analgesic
Category C GI: history.Tramadol is not
constipation, recommended for
nausea, patients dependent on
abdominal opioids or who have
pain,anorexia,di previously received
arrhea,drymout opioids for more than
h,dyspepsia,flat 1week; may cause
ulence,vomiting. Opioid Withdrawal
symptoms.
GU:
menopausal ●Monitor patient for
symptoms, seizures. May occur
urinary within recommended
retention/freque dose range.
ncy.

Derm: pruritus,
sweating.

Neuro:hyperton
ia.misc:serotoni
n
syndrome,physic
aldependence,p
sychological
dependence,tole
rance.
 Drug Name Dosage Mechanism of Indication Contraindication Side/ Adverse Nursing Responsibilities
and Action Effect
Frequency
Generic Inhibits the Treatment of: Contraindicated CNS: agitation, ●Assess overall health
Name: synthesis of Mild pain, Fever in: Previous anxiety, status and alcohol usage
prostaglandins hypersensitivity; headache before administering
acetaminophen that may serve IV Treatment Products fatigue, insomnia acetaminophen.Patientsw
as mediators of: Mild to containing hoare malnourished or
Brand Name: of pain and moderate pain, alcohol,as RESP:atelectasis chronically abuse alcohol
Abenol, fever, primarily Moderate to partame, ,dyspnea are at higher risk of
Acephen, Acet, in the CNS. severe pain saccharin, sugar, developing hepatotoxicity
APAP, Artritol, Has no with opioid or tartrazine (FDC CV:hypertension with chronic use of usual
AspirinFreeAna significant anti- analgesics, yellow dye #5) , hypotension, doses of this drug.
cin, Atasol, inflammatory Fever. should be avoided
Cetafen properties or in patients who GI:hepatotoxicit ●Assess amount,
GI toxicity have y frequency, and type of
hypersensitivity Constipation,qliv drugs taken in patients
Classification or intolerance to erenzymes,naus self-medicating,
: these ea, vomiting especially with OTC
Therapeutic:an compounds;Sever drugs. Prolonged use of
tipyretics, ehepatic GU: renal failure acetaminophen increases
Nonopioid impairment/active (high the risk of adverse renal
analgesics liver disease. doses/chronic effects. For short-term
use). use, combined doses of
acetaminophen and
HEMA: salicylates should not
neutropenia, exceed the
pancytopenia. recommended dose of
either drug given
MS: alone.Do not exceed
 musclespasms,tri maximum daily dose of
smus, acetaminophen when
considering all routes of
DERM: acute administration and all
generalized combination products
exanthematous containing
pustulosis,steven acetaminophen.
s-
johnsonsyndrom ● Pain: Assess type,
e,toxicepidermal location, and intensity
necrolysis,rash,u prior to and 30–60 min
rticaria. following administration.

●Fever: Assess fever;

note presence of
associated signs
(diaphoresis, tachycardia,
and malaise).
Source:Lippincott Williams and Wilkins. Nursing IV Drug Handbook 9th Edition, Philadelphia
 Drug Name Dosage and Mechanism of Indication Contraindication Side/ Adverse Nursing Responsibilities
Frequency Action Effect

Generic Binds to an Erosive Contraindicated CNS: headache ●Assess patient routinely

Name: enzyme in the easophagitis in: Previous for epigastric or
presence of associated with hypersensitivity; GI: abdominal pain and for
Pantoprazole acidic gastric GERD. OB; should be pseudomembran frank and occult blood in
pH,preventing Decreased used during ous colitis, stool, emesis ofr gastric
Brand Name: the final relapse rate of pregnancy only if abdominal pain, aspirate
Pantoloc, transport of daytime and clearly needed; diarrhea,eructati
protronix IV, hydrogen ions nightime lactation on,flatulence ●Monitor bowel function,
protronix into the heartburn discontinue diarrhea, abdominal
gastric lumen. symptoms in breastfeeding due ENDO: cramping,fever and it
Therapeutic patient with to potential for hyperglycemia should be reported
Classification effects: GERD. serious adverse MS: bone immediately to health
: diminished Pathologic reactions. fracture care professional
Therapeutic:an accumulation gastric promptly as a sign of
ti ulcer agent of acid in the hypersecretory F AND E: pseudomembranous
Pharmacologic: gastric lumen, condition. Hypomagnesemi colitis. May begin up to
proton-pump with lessened a several weeks following
inhibitor acid reflux. cessation therapy.
Healing of
duodenal ● Pain: Assess type,
ulcers and location, and intensity
easophagitis. prior to and 30–60 min
Decreased following administration.
acid secretion
in
hypersecretor
y conditions.
 Drug Name Dosage and Mechanism of Indication Contraindication Side/ Adverse Nursing
Frequency Action Effect Responsibilities

Generic Name: Block stimulation Hypertension Contraindicated CNS: ●Asses for

of (ischemic or in: history dizziness,fatigue, orthostatic
Carvedilol beta,(myocardial cardiomyopathic serious (steven weakness, hypotension
) and ) with digoxin, johnson anxiety,depressi when assisting
beta,(pulmonary diuretics and angioedema, on,drowsiness,in patient up from
Brand Name: ,vascular,and ACE inhibitors. anaphylaxis) somnia,memory supine
Coreg, coreg CR uterine) Left venticular pulmonary loss, mental position.Monitor
adrenergic dysfunction after edema, status changes, BP and pulse
receptor sites. myocardial cardiogenic nervousness, frequently
Classification Also has alpha, infarction. shock, nightmares. during dose
Therapeutic:anti blocking activity, bradycardia, adjustment
Hypertensives which may result heart block or EENT: blurred period and
Pharmacologic: in orthostatic sinus vission, dry periodically
beta-blockers hypotension. syndrome(unless eyes, during therapy.
Therapeutic if facemaker in intraoperative
effects; place) floppy iris ● Assess patient
decreased heart uncompensated syndrome, nasal routinely for fluid
rate and BP. HF requiring IV stuffiness. overload,
Improved inotropic agents. peripheral
cardiac output, RESP: edema, dyspnea,
slowing the bronchospasm, rales/crackles,
progression of wheezing fatigue weight
Hf and gain, jugular
decreased risk of GI: venous
death. diarrhea,constip distention.
ation,nausea
 Monitor
ENDO: intake and
hyperglycemia output ratios
,hypoglycemia and daily
MS: arthralgia, weight.
back pain,
muscle cramps
F AND E:
Hypomagnesemi
a
 Drug Name Dosage and Mechanism of Indication Contraindication Side/ Adverse Nursing
Frequency Action Effect Responsibilities

Generic Name: Both parent To decrease Hypersensitivit CV: ● Asses patient for
drug and its the y; Active bradycardia symptoms of stroke,
Ticagrelor active incidence of bleeding; Resp: peripheral vascular
metabolite thrombotic History of dyspneya disease, or MI
inhibit cardiovascul intracranial Endo: periodically during
Brand Name: platelet ar events bleeding; Sever gynecomastia therapy.
Brilinta aggregation associated e hepatic Hemat:
by with acute impairment BLEEDING ● Observe patient
reversibility coronary (increase risk Misc: for signs and
Classification interacting syndrome of bleeding); hypersensitivity symptoms of
Therapeutic:anti with platelet (ACS) Impending reactions hypersensitivity
platelet agent P2Y.ADP- coronary artery including reactions (rash,
Pharmacologic: receptors, bypass graft ANGIOEDEMA facial swelling,
platelet preventing pruritus, laryngeal
aggreagation signal edema, wheezing).
inhibitors transduction Discontinue drug
and platelet and notify health
activation. care professional
Therapeutic immediately if
Effects: symptoms occur.
Reduces Keep epinephrine, an
sequele of antihistamine, and
ACS including resuscitation
cardiovascula equipment close by
r death, MI in case of
and stroke anaphylactic
reaction.

● Instruct patient to
notify health care
professional o all Rx
or OTC medications,
vitamins, or herbal
products being taken
and consult health
care professional
before taking nay
new medications,
especially aspirin or
NSAIDs.
● Advise patient to
notify health care
professional if
pregnancy is
planned or
suspected or if
breast feeding.