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09.venous Dis PDF
09.venous Dis PDF
Chronic Venous
Insufficiency in
General Practice
Varicose Veins and associated symptoms
How to proceed
classification? 8/9
instrumental diagnosis
cw Doppler 16
Duplex ultrasound 17
Venous Pump Function Test 18
Venography 19
TREATMENT?
Conservative 20
Sclerotherapy 21
Phlebectomy 22
Stripping 23
selected bibliography 26
1
Is the diagnosis «Varicose Veins» enough? 14, 15, 18, 23
Large Varicose Veins (CEAP-Classification C2)
Great saphenous vein with Circumflex vein: lateral branch Small saphenous vein –
pronounced chronic venous of the greater saphenous vein varicosis
insufficiency in medial ankle area
Do complications occur? 23
?
Valvular insufficiency of deep-, superficial-,
Check presence of
and perforating veins results in:
CVI in ankle area?
venous hypertension with
signs of chronic venous
insufficiency
mild or medium reticular veins, Combination of pronounced Skin changes resulting from
spider veins, mild superficial trun- reticular varicosis and spider venous insufficiency (with or
cular varices veins, pronounced truncular without varices, often seen
varicosis and insufficient perfo- with corona phlebectatica)
rating veins
Superficial Thrombophlebitis
Varicosity
combined
with:
Embolus
Varicose Veins occur frequently 23
+ ++ +++
44 % 9% 3%
Varicosis + ++ ++
Complications Ø + ++
depends on
symptoms or
complaints
More than 50% of the adult working population suffer from varicose veins
or from signs of chronic venous insufficiency. The frequency rises with
increasing age (23).
Varicosity – Progression to be observed 23, 25
+ ++ +++
Skin changes 21 34 56
Oedema 8 19 30
Ulceration 1 1 20
Phlebitis 8 17 37
Classification? CEAP 18
C
Clinical Classification
C Clinical picture
C0 no clinical signs
C1 small varicose veins
C2 large varicose veins
Inspection, Palpation
C3 edema
(Doppler)
C4 skin changes
C5 healed ulcer
C6 active ulcer
E
Etiology
E Etiology
EC Congential
EP Primary Medical history
ES Secondary
A
Anatomy
A Anatomy
AS Superficial
Inspection
AD Deep
Additional examination
AP Perforating veins
P
Pathophysiology
P Pathophysiology
PR Reflux Additional examination
PO Obstruction (Basis = Duplex)
An anatomical score, a clinical score and a score for the evaluation of the
patient’s disability serve further differentiation:
Clinical Classification (C) with examples
C 1 E PA S P R C 2 E PA S,p P R
C 3 edema+Corona C 4 lipodermato
sclerosis and eczema
C 3 E s A d P o,R C 4 E PA S,P P R
C 5 E s A S,d,P P o, r C 6 E s A d, p P R
Medical history – specific questions? 2, 9, 23
Patient complaints?
Exacerbated:
• when sitting, standing, travelling
• in warm environment
• in the evening
• premenstrual syndrome (PMS)
10
Differential Diagnosis: Further Investigations
rheumatological
▼▼▼▼▼
LEG ACHE neurological
but not specifically orthopedic caUses
lymphatic
vein achE
arterial
Foot arches
Joints
Spine / nerves
11
Venous examination: points to be considered 15, 18, 23
1 degree of varicosity
Pronounced
2
12
…patient in supine position
4 comparative palpation
with muscles relaxed.
5
6
CIRCUMFERENCE:
indicate exact height and time
of day
13
When are additional tests necessary? 8, 14
14
Etiology of Varicose Veins 23, 24
Pathogenesis
Primary varicosities Secondary varicosities
Venous wall weakness, Blockage or insuffici-
valvular insufficiency ency in deep veins
in superficial and deep
vein
in the superficial venous system The pathological in the deep venous system
process begins
Hypothetical Established
Heredity and environmental Thrombosis, valvular
factors, e.g. age, Etiology dysplasia, obstruction,
occupation, pregnancy, tumor, arterio-venous
overweight shunt
95% Frequency 5%
15
Instrumental Diagnosis CW Doppler 8, 14
Ein Ein
0 0
Doppler Doppler
distal distal
Valsalva Valsalva
Aus Aus
proximal proximal
Doppler Doppler
0 0
distal distal
16
Duplex ultrasound 4, 8, 14
principle
B-Imaging: Imaging of vessels and surrounding tissues
Doppler: • Quantification and direction of blood flow
• Hemodynamic information displayed in color and superimposed on morphological
image
Sapheno-femoral junction
performance
Advantage: High information content, non-invasive
Disadvantage: User dependent picture, does not give overview picture
Distal thigh
Great saphenous vein (longitudinal section)
17
Venous Pump Function 14, 19, 21
Principle
Recording of volume or pressure changes at the distal lower extremity leg
during ankle-movement (tip-toes, knee bending, walking)
Methods
Photoplethysmography, strain gauge-plethysmography, foot volumetry,
air plethysmography (APG), measurement of pressure in a dorsal foot vein.
Pump
Normal: competent incompetent Pathological:
Movement ac- No reduction of
tivates the venous blood volume
blood pump. Re- (pressure) as a
duction of local result of valvular
blood volume insufficiency.
and venous pres- Blood flows back
sure in the foot and forth.
and distal lower
leg
Normal venous pump Venous (pump) insufficiency
Normaliza- No normali-
tion of pumping zation of pum-
by elimination of ping: incompe-
superficial reflux: tent deep veins
normal valvular
function of deep
veins
18
Venography 10, 11, 12, 14
Varicosity at ankle
Cockett
Ankle perforating vein
Stem varicosity greater
saphenous vein
(white arrows)
19
Treatment Conservative? 1, 17
Purpose
to alleviate discomfort, to prevent progression and complications
1 Prophylaxis
• Regular exercises («muscle pump»)
• Elevation of legs
• Advice for patients confined to bed, travelling
Sklero- Phleb-
sierung ektomie Operation
2 compression treatment
• Compression bandage: fresh swelling,
ulceration, lymphatic oedema, angiodyspla-
sia, venous swelling.
• Medical compression stocking for
leg complaints, pregnancy, pronounced
varicosis, CVI
Beratung
Kompressionsbehandlung 3 active treatment
Medikamente • Sclerotherapy
• Phlebectomy
• Surgery
4 medication (does not substitute points 1–3)
Patient information
Implications, possible complications
Any active treatment:
• removes only existing varices
• disposition to varicosis remains
20
Sclerotherapy 7, 16, 20, 22, 24
indications/
principle contraIndications Technique
• Sclerosing agent destroys Indication Different methods were descri-
endothelium. Spider veins, side branch varico- bed, e.g. by Sigg, Tournay,
sis, residual and recurring posto- Fegan. New procedures include
• Plasma leaks into the vein
wall, fibrin formation. Che- perative varicose veins. ultrasound assisted injection
motactic signals activate the which is also suitable for sclero-
connective tissue cells which Contraindication therapy of the sapheno-femoral
obliterate the vein lumen. Confinement to bed, allergy, junction (20), and foam-sclero
pronounced oedema, peripheral therapy (7).
arterial occlusive disease (systolic
ankle-pressure below 80 mm Hg),
1. trimenon of pregnancy,
recent thrombosis.
Side effects
Inflammation, pigmentation,
matting, ulceration (CAVEAT: in-
traarterial injection!)
New techniques
Echo-Sclerotherapy Foam-Sclerotherapy
(Injection controlled by Duplex)
21
Phlebectomy 13, 16, 19, 22
indication/
principle contraindication technique
Removal of individual varices Indication Anesthesia of skin directly above
and smaller perforating veins by Varices of any size, except varicose vein. Incisions 1–3 mm
incisions under local anestesia. hyphen webs. For main stem long at intervals of 3–10 cm.
(«Outpatient phlebectomy» by varicosities, branch ligation Varices are extracted from the
Muller13). or stripping are required in elevated leg using a special
addition. hook. Careful compression ban-
daging, no ligature of vessels
Contraindication and no suture of vein
cf. sclerotherapy and stripping. required.
22
Stripping 3, 5, 6
Indication /
principle contraindication Technique
Comprehensive correction Indication Minor operations are possible
under one-time anesthe- Superficial main stem varicosi- on outpatient, basis major sur-
sia: ties, especially for larger gery better in hospital.
Ligation of side branches, vein varices
stem is ligated at junction (Fig. Spinal or general
1). Vein is stripped and removed Contraindications anesthesia
with flexible wire (Fig. 2). • Thrombosis in recent months New techniques:
Perforating veins are ligated, • Lymphatic oedema Subfascial endoscopic perfora-
e.g., with endoscopy (Fig. 3). (debatable) tor sugery (SEPS), Cryoprobe,
Phlebectomy using clamp (Fig. 4) obliteration with heat source
Side effects (electromagnetic waves, laser).
POSTOPERATIVE Sensory disturbance of femoral TIPP (transilluminated powered
Compression for 3 weeks and calf nerves, occasionally phlebectomy=removal of side
hematomas and symptoms due branches by suction). Paratibial
to scarring. Scarring is rare. fasciotomy in CVI.
23
Medical
Compression Stockings 17
Contraindications Cautions
Contraindications:
• Seriously
Arterial insufficiency, intermittent impaired
claudication, ischemiaarterial blood flow,
• oozing
Signs ofdermatoses,
infection infections, decompensated
• Uncontrolled congestive heart failure • Extensive venous ulceration
c• ardiac failure, diabetic neuropathy and
Acute dermatitis, weeping dermatosis, cutaneous sepsis
microangiopathy. Unless
•
prescribed otherwise
Skin sensitivities or allergies
by physician compression
stockings
• class 30 mmHg or greater are not
No liability accepted for non-observance of contraindicationsworn during bedrest/confinement
• Neuropathy to bed. No liabiliy accepted for
non-observance of contraindications. • History of diabetes
• Confinement to bed or non-ambulatory use unless
otherwise prescribed by the physician
• No liability accepted for non-observance of cautions
24
Compression Stockings – how to prescribe?
1. Number of Stockings
3. Compression level
4. «Made-to-measure»-stockings, if necessary
5. Special fixation/grip-tops
7. Open/closed foot
25
Selected Bibliography
1 ABENHAIM L., CLEMENT D., NORGREN L. et al.: The management of chronic venous disorders of
the leg: an evidence-based report on an international task force. Phlebology 14, Suppl. 1, 1999
2 BLÄTTLER W.: Über einen eventuellen Zusammenhang zwischen Venenbeschwerden und
psychischem Befinden. VASA 1991 Suppl. 32:599
3 BRUNNER U.: Die Chirurgie des oberflächlichen Venensystems. In: Breitner: Chirurgische
Operationslehre, 2.Aufl./1993, Band Xll Teil 1: Gefäßchirurgie
4 EICHLISBERGER R., FRAUCHIGER B., JÄGER K.: Abklärungen der Beinvenen mit Duplexultraschall.
Therap. Umschau 48, 697, 1991
5 FISCHER R.: Die chirurgische Behandlung der Varizen. Aktuelle Probleme in der Angiologie:
29. H. Huber, Bern, Stuttgart, Wien, 1976
6 FISCHER R.: Eine neue Generation der Varizenchirurgie? Vasa 20, 311 (1991)
7 HENRIET P.: Foam-Sclerotherapy. In press.
8 JÄGER K., BOLLINGER A.: Duplex-Sonographie der Becken- und Extremitätenvenen. Praxis der
Doppler-Sonographie (Hrsg.: Kriessmann A., Bollinger A., Keller H. M.), Thieme, Stuttgart, 118,
1990
9 LEU A. und LEU H. J.: Pein im Bein – Differentialdiagnose von Ödem/Schmerzen der unteren
Extremitäten. VASA 18, 246, 1989
10 LEU H. J.: Pathomorphology of Vascular malformations. Intern. Angiology 9,147, 1990
11 MAY R., KRIESSMANN A.: Periphere Venendruckmessung. Thieme, Stuttgart 1978
12 MAY R., WEBER J. (eds.): Pelvic and Abdominal Veins. Progress in Diagnostics and Therapy.
Excerpta Medica, Amsterdam, Oxford, Princeton, 1981
13 MULLER R.: La phlébectomie ambulatoire. Phlébologie 31, 273 (1978)
14 NICOLAIDES AN., Investigation of Chronic Venous Insufficiency – A Consensus Statement.
Circulation 102,e126 (2000)
15 OESCH A.: Formen und moderne Therapie der Varikosis. Schweiz. med. Wschr. 1242 (1988)
16 OESCH A.: Indikationen und Ergebnisse der ambulanten Varizentherapie. Therap. Umschau 48,
692 (1991)
17 PARTSCH H., RABE R., STEMMER R.: Kompressionstherapie der Extremitäten. Editions Phlebologi-
ques Françaises , Paris, 1998
18 PORTER JM., MONETA GL., International Consensus Committee on Chronic Venous Disease:
Reporting Standards in Venous Disease: An Update. J Vasc Surg 21, 635, 1995
19 RAMELET AA., MONTI M., Phlebology. The Guide. Elsevier Amsterdam 1999
20 Schadeck M., Duplex Phlebology. Gnocchi, Napoli 1994
21 Weber J., May R.: Funktionelle Phlebologie, Phlebographie, Funktionstests, interventionelle
Radiologie. G. Thieme, Sturttgart-New York, 1990
22 Weiss RA., Feied CF., Weiss M.: Vein diagnosis and treatment. McGraw-Hill, New York 2001
23 Widmer LK., Stähelin HB., Nissen C., da Silva A.: Venen-, Arterien-Krankheiten, koronare
Herzkrankheit bei Berufstätigen. Hans Huber, Bern, Stuttgart, Wien 1981
24 WUPPERMANN Th.: Varizen, Ulcus cruris und Thrombose, Springer-Verlag, Heidelberg 1986
25 Zbinden O.: Progredienz der Varikosis. Veränderung des Varizenbefundes in 11 Jahren. Thesis,
Universität Basel 1994
26
This leaflet can be
ordered separately!
27
Advices
Unlike in other diseases, the patient can take preventive measures against the development of venous diseases and can
support the physician with treatment of the disease.
No. 1
This means: more movement, walking, walking the stairs, gymnastics, cycling, swimming and all other sports which
activate the muscles of the leg.
NO. 2
When sitting or standing cannot be avoided:
activate muscle pump!
This means: when sitting or standing, feet should be frequently moved up and down
(«pumping»).
At work, or during long tavel hours in car, train or plane: get up/out more often and move a
few steps.
NO. 3
wrong During the day:
foots higher on a chair
on the windowsill
than on the desk
the heart
At night:
15 cm right elevate foot of the bed,
ideally the frame is adjustable,
or put a pillow under the
matress
This means: relieving the veins by repeated 15 cm
leg elevation.
NO. 4
Avoid excessive heat
28
NO. 5
Avoid overweight
NO. 6
Consequent, daily wearing of medical compres-
sion stockings. In general, «support stockings»
prove not to be sufficient
Special cases
• Confinement to bed
Lying in bed for a longer period of time in the hospital or at home, can lead to thrombosis (formation of blood clots in the
veins). This can affect in particular patients suffering from venous disease, but also healthy people.
i m p r o v i n g q u a l i t y o f l i f e
11.06/19429/LIT-VVCV
ISO9001/EN46001