Mechanism Indication Contraindication Adverse Nursing Responsibilities

of Action Reactions
Generic Dosage: • Decreased • Relief of Celecoxib is Constipation; • Assess patient’s range of motion,
Name: 200mg pain and signs and contraindicated in diarrhea; degree of swelling, and pain in affected
Frequenc inflammation symptoms patients with known dizziness; joints before and periodically
celecoxib y:bid ; prn caused by of hypersensitivity to gas; throughout therapy.
arthiritis osteoarthriti celecoxib. headache;
Brand s. heartburn; • Assess patient for allergy to
name: Pharmacologi Celecoxib should not nausea; sore sulfonamides, aspirin, or NSAIDS.
c Mechanism • Relief of be given to patients throat; Patients with these allergies should not
Celebrex signs and who have stomach receive celecoxib.
• Prevention symptoms demonstrated allergic- upset; stuffy
Classificati of M  Inhibits of type reactions to nose. • May be administered without regard to
on: the enzyme rheumatoid sulfonamides. meals.
Celecoxib COX-2. This arthritis in
is a enzyme is adults. Celecoxib should not • Instruct patient to take celecoxib
nonsteroidal required for be given to patients exactly as directed. Do not take more
antiinflamm the synthesis who have experienced than prescribed dose. Increasing doses
atory drug of asthma, urticaria, or does not appear to increase
(NSAID) prostaglandins allergic-type reactions effectiveness.
that is used . after taking aspirin or
to treat other NSAIDs. • Advise patient to notify health care
arthritis, • Has Severe, rarely fatal, professional promptly if signs or
pain, analgesic, anaphylactic-like symptoms of GI toxicity (abdominal
menstrual anti- reactions to NSAIDs pain, black stools), skin rash,
cramps, and inflammatory, have been reported in unexplained weight gain, edema occurs.
colonic and such patients .
polyps. antipyretic •Patient should discontinue celecoxib
properties. Celecoxib is and notify health care professional if
contraindicated for the signs and symptoms of hepatotoxicity
treatment of peri- (nausea, fatigue, lethargy, pruritus,
operative pain in the jaundice, upper right quadrant
setting of coronary tenderness, flu-like symptoms) occur.
artery bypass graft
(CABG) surgery