Abstracts - Aspire: ART Paving the way for new frontiers
AC-019 Result: This study has been conducted to 65 women, with
mean age for day-2 transfer of 35.24 years (SD = 5.48) and Correlation between endometrial thickness, triple line for day-3 transfer 34.42 years (SD = 3.11). Mean infertility pattern and blood flow, and combinations of these period for day-2 transfer was 6.72 years (SD = 3.26) and for parameters, with successful pregnancy outcome in an IVF day-3 transfer 6.16 years (SD = 3.17). The study found an programme higher rate of pregnancy outcome for day-3 transfer (63.2%) Djuwantono T, Permadi W, Chandra R, Rifayani S, Harlianto H compared with day-2 transfer (30.4%). Factors that have an Aster Fertility Clinic, Hasan Sadikin Hospital, Indonesia effect on successful pregnancy rate were number of oocytes djuwantono@yahoo.com (P = 0.003), embryo quality score (P = 0.001), while factors Introduction: The successful rate of IVF programme is still which did not were difficult transfer techniques (P = 1.00), and pretty much unfavourable as it depends on the endometrial blood/mucus contamination on catheter (P = 1.00). According receptivity and until this present moment there are still no to double logistic regression analysis, total embryo score was known gold standard evaluation criteria. the most reliable predictor to successful post-ovum retrieval Materials/Methods: an analytic correlation prospective pregnancy rate (OR = 2.104, CI = 0.592–64.380). cohort study was conducted on women who participated in IVF Conclusions: The day-3 embryo transfer showed an increase in programme at Aster Fertility Clinic, Dr Hasan Sadikin General pregnancy outcome rate. Factors such as increasing number of Hospital, Bandung. oocytes, embryo quality total score have effect on the increase Results: This study has been conducted on 73 women, and of pregnancy outcome rate, while difficult transfer techniques the confirmed clinical pregnancy rate was 38.4%, with mean and blood/mucus contamination on catheter do not. The most age of 35 years (4.76) and infertility history time frame was dominant factor is embryo quality score. 6.4 years (3.37). The cut-off point of endometrial thickness AC-021 was 9.2 mm. Cases with endometrial thickness of ≥9.2 mm found in 83.6% of cases with 45% successful pregnancy rate Effect of two different courses of ultralong down- and a possibility of 37%, while for those of ≤9.2 mm, they regulation with gonadotrophin-releasing hormone agonist were 16.4%, 7.7%, and 37%, respectively. The triple line as depot on outcome of IVF in stage III/IV endometriosis well as blood flow patterns were detected in 76.7% and 50.7% Halim B, Lutan D, Tanjung MT of cases with mean pregnancy outcome of 48.2% and 64.9%, Halim Fertility Center, Dept O and G, USU, Indonesia while the chances were 37% and 33% respectively. The most binarwan2002@yahoo.com influential factors on a successful pregnancy outcome were, in Introduction: To compare the effect of 3-month and 6-month order, endometrial blood flow pattern (OR = 9.31, P = 0.001), courses of gonadotrophin-releasing hormone (GnRH) agonist endometrial thickness (OR = 7.89) and triple line pattern of the depot for ultralong down-regulation on outcome of IVF. endometrium (OR = 5.16). The chance of clinical pregnancy Materials/Methods: Twenty-nine patients with stage III/IV with all these three parameters in combination were 71.5%. endometriosis after surgery in Halim Fertility Centre, Dept Conclusions: There was a significant correlation between O and G, H. Adam Malik Hospital, Medan, Indonesia were the endometrial thickness, triple line pattern and endometrial randomized into two groups of 15 patients for 3-month and blood flow with outcome of successful pregnancy rate. The 14 patients for 6-month course of GnRHa depot for ultralong combination of these three parameters could predict the down-regulation before undergoing standard protocol of outcome of clinical pregnancy rate even better. ovarian stimulation in IVF cycles. Length and dosage of gonadotrophin use, number of oocyte retrieved, number of AC-020 embryo transferred and clinical pregnancy rate were recorded Differences between day-2 and day-3 embryo transfer in both groups and compared. following ovum retrieval procedure and factors Results: There were no differences in length and dosage use influencing successful outcomes in an IVF programme of gonadotrophin in both groups, the number of oocyte and Harlianto H, Djuwantono T, Permadi W, Konstantine V, number of embryo transferred. Clinical pregnancy rate in both Nataprawira D groups were comparable (40% versus 35.7%) P < 0.05. Aster Fertility Clinic–Hasan Sadikin Hospital, Indonesia Conclusion: Outcome of IVF in ultralong down-regulation harrisharlianto@yahoo.com with GnRHa depot in stage III/IV endometriosis with a 3- month course and with a 6-month course of GnRHa depot in Introduction: Embryo day transfer still based on the number IVF were similar. of fertilization. But the influence of embryo transfer on day 2 or day 3, or the effect of factors contributing to the pregnancy AC-022 rate, such as number of oocytes, total embryo quality score, difficult transfer techniques, and blood/mucus contamination on Low-dose urine HMG stimulation improves clinical catheter, on the successful pregnancy outcome rate are not well outcomes of women with poor-responder indication in known. Even the most influential factor is not being explored IVF/ICSI treatment when compared with natural cycle yet. The aim of the study was to know the difference of day-2 Gong F, Lu GX, Li J, Zhang SP, Lin G and day-3 embryo transfer in accordance to pregnancy rate, to Reproductive and Genetic Hospital Of CITIC-XIANGYA, know the effect of factors and decide the dominant factor. China Materials/Methods: This study was an experimental linggf36@yahoo.com.cn laboratory research with prospective approach conducted to Introduction: Poor responders were not sensitive to high-dose women that enrolled to an IVF programme in Aster Fertility gonadotrophin stimulation and usually resulted in low success Clinic, Hasan Sadikin Hospital Bandung from October 2006 rate in IVF treatment. Natural cycle is commonly used but high to October 2007. cancellation rate were observed due to unsuccessful oocyte S-25 Reproductive BioMedicine Online, Vol. 16, Suppl. 2, April 2008