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INTRODUCTION
INTRODUCTION
( https://shodhganga.inflibnet.ac.in/bitstream/10603/70686/17/chapter%202.pdf)
A part of our body is completed mostly of collagen, it delivers a soft framework in a form
of protein and give calcium phosphate in which a mineral that enhances strength and strengthens
the framework. This part of the body is the bone in which it is identify as living and growing
tissue. The mixture of collagen and calcium makes bone both flexible and strong, which in turn
helps bone to withstand stress. More than 99 percent of the body’s calcium is contained in the
bones and teeth. The remaining 1 percent is found in the blood. Throughout one’s lifetime, old
bone is removed, and new bone is added to the skeleton. During childhood and teenage years,
new bone is added faster than old bone is removed. As a result, bones become larger, heavier,
and denser. Bone formation outpaces resorption until peak bone mass is reached, typically by the
late 20s. After that time, bone resorption slowly begins to exceed bone formation. For women,
bone loss is fastest in the first few years after menopause, and it continues into the
postmenopausal years. Osteoporosis – which primarily influences ladies but may moreover
influence men – will create when bone misfortune happens as well rapidly or when bone
arrangement happens as well gradually. Osteoporosis is more to be expected to grow if you did
not range optimal peak bone mass during your bone-building
years.(https://www.bones.nih.gov/health-info/bone/osteoporosis/overview)
As stated by Basaran et al. (2017) It was evaluated that the number of patients around
the world with osteoporotic hip breaks is more than 200 million. It was detailed that in both
Europe and the Joined together States, 30% ladies are osteoporotic, and it was assessed that
40% post-menopausal ladies and 30% men will encounter an osteoporotic break within the rest
of their lives. Osteoporosis is additionally an imperative wellbeing issue in Turkey, since the
number of more seasoned individuals is expanding. The rate for hip break increments
exponentially with age in all countries as well as in Turkey, which is obvious within the FRACTURK
consider. It was assessed that around the age of 50 a long time, the likelihood of having a hip
break within the remaining lifetime was 3.5% in men and 14.6% in ladies.
Majority of osteoporotic fractures are cause by falls; therefore, it is a need for the
structured for the efficient treatment of osteoporosis in order to prevent falls like program. Older
and frail persons especially who those who are experiencing stroke and taking medications that
lessen mental alertness are particularly predisposed near falls. On the other hand, several
interventions reduce the risk of falling but unfortunately none of them reduce the risk of fractures.
Hip protectors are a must nowadays for people who are experiencing osteoporosis because reduce
the risk of fracture, but it does not reduce the risk of falling. Patients at an older age with sever
kyphosis, back discomfort and gait instability could benefit from weight-bearing exercises, back
strengthening, and balance training therapies.
Bone quality can be characterized utilizing BMD (70%) and bone quality (20%). It is simple
to measure Bone Mineral Density (BMD), but, in clinical settings, bone quality isn't quantifiable
however. The determination of osteoporosis is set up by the estimation of BMD or by the event
of a fragility break of the hip or vertebra or within the nonappearance of major injury (e.g., engine
vehicle mishap or drop from numerous stories). Research facility testing uncovered no auxiliary
causes of osteoporosis. Bone mineral thickness can be effectively measured to identify bone
thickness, but the degree of disintegration of the bone tissue cannot be measured in clinical
settings, except for the biochemical markers of bone tissue.
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335887/)
According to Lorentzon and Cummings (2015). In 1822 land surgeon and anatomist Sir
Astley Paston Cooper wrote on an observed association with distorted bones and fractures. Jean
Lobstein, a French pathologist and surgeon, was the primary to use the word ' osteoporosis' in
1835, although he identified a disease of blue-gray sclera, which was possibly an incomplete sort
of osteogenesis.In 1941, after the loss of ovarian function Fuller Albright reported cases of ladies
with vertebral fractures. Oestrogen therapy restored those women's calcium balance and reversed
their height loss 7. Such results were the premise for identifying postmenopausal osteoporosis,
and therefore the connection between osteoporosis and vertebral fractures was identified.Several
subsequent studies have shown that vertebral fractures indicate reduced bone strength and
structural bone deterioration. Vertebral fractures represent the extent of osteoporosis and are
effective predictors of potential fractures, making them a trademark of disease 8, 9.