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Progeria Articles
Progeria Articles
Progeria is a rare genetic condition that causes a person to age prematurely. Children with
progeria appear healthy, but by the age of 2 years, they look as if they have become old too
fast. There are different types of progeria, but the classic type is known as Hutchinson-
Gilford progeria syndrome (HGPS).
It is caused by a mutation in the lamin A (LMNA) gene, and it involves severe hardening of
the arteries from a young age.
Children with this condition live on average for 14 years, because of the likelihood of
developing atherosclerosis.
Around the world, 134 children are thought to have progeria across 46 countries. It is
believed to affect 1 in every 4 million newborns of both sexes and all ethnicities.
Thirty years ago, little was known about the cause of progeria. In 2003, a progeria gene was
discovered. This has given hope that a cure might one day be found.
It is sometimes called "Benjamin Button disease," after Scott Fitzgerald's fictional character.
However, in the story, "The Curious Case of Benjamin Button," Fitzgerald's character ages
backward. People with progeria age forward but quickly.