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VERY RELIABLE ANTIBODIES
Evidenced by advancing science.
Validated by enhanced validation.
Supported by 1000`s of publications.
Created by The Human Protein Atlas.
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Synaptic signaling is
SY
cell-cell communication that
occurs at the synaptic level.
When the sending neuron
fires, an electrical impulse
travels along the axon.
As soon as the impulse
reaches the synapse, it
triggers the release of
neurotransmitters.
Anti-NEFL monoclonal antibody
(AMAb91314) shows strong
immunoreactivity in neuronal
cell bodies and processes in the
rat cerebral cortex.
PrecisA Monoclonals are mouse
monoclonal primary antibodies
developed against a number of
carefully selected targets.
Clones are selected to recognize
only unique non-overlapping
epitopes and isotypes.
Triple A Polyclonals are rabbit
polyclonal primary antibodies
developed within the Human
Protein Atlas project.
IHC characterization data from
44 normal tissues and 20 cancers
is available on the Human Protein
Atlas portal.
Brain Posters.indd 3
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AtlasPoster Ad 194x260 Final verison.indd 1
+41-43-243-1358
rgoncalves@science-int.co.uk Editor: Sean Sanders, Ph.D.
Europe, Middle East, and India Illustration/Design: Mattias Karlén
Custom Publishing Bioinformatics: Per Oksvold, Linn Fagerberg, Ph.D., Wen Zhong, Ph.D., and Kalle von Feilitzen
Roger Goncalves, Sales Manager Authors: Evelina Sjöstedt, Ph.D., Jan Mulder, Ph.D., Tomas Hökfelt, Ph.D., and Mathias Uhlén, Ph.D.
Senior Editor, Custom Publishing, Science/AAAS
Sean Sanders, Ph.D.
pathology of neurodegenerative and other brain diseases. across the brain in amazing three-dimensional detail.
give researchers a means to investigate the etiology and is providing unprecedented detail about neural connections
more complete understanding of normal brain function and cures for neurodegenerative diseases. Electron microscopy
these insights will provide a foundation upon which to build a subcellular processes and potentially uncover causes and
interactions between different brain cells. It is hoped that microscopy is taking us beyond the cellular level to reveal
inner workings of individual cells, in addition to data on painful memory or playing a sport. Superresolution
With this information, scientists can gain insights into the different tasks or thought processes, like when recalling a
understand which parts of the brain are activated during
protein targets in human and mouse brains. magnetic resonance imaging (fMRI) is helping us
as well as protein-localization data collected for selected Increasingly, high-resolution imaging such as functional
protein-coding genes found in human, pig, and mouse brains
Brain Atlas contains genome-wide RNA profiles of all from multiple angles.
level. A subsection of the Human Protein Atlas, the Human scientists from trying, and they’re attacking the problem
across all regions of the brain and, incredibly, at a single-cell complex to comprehend! Fortunately, this has not stopped
knowledge about where RNAs and proteins are expressed complex enough to comprehend itself, it would be too
described on the front of this poster, is adding a wealth of The paradox has been put forward that if the brain was
And now, the Human Brain Atlas (www.proteinatlas.org/brain), The brain is arguably the most complex organ in our body.
Produced by the Science/AAAS Custom Publishing Office Sponsored by
ANTIBODIES FOR NEUROSCIENCE VERY RELIABLE ANTIBODIES
Building on our heritage with the Human Protein Atlas project,
Antibodies are valuable tools in the ongoing scientific effort to we provide highly validated reagents that enable leading
gain more knowledge about the human brain, to understand research in biology, diagnostics, and medicine for the purpose of
understanding and improving human health. We are the original
the fundamental and emergent properties of neurons and
manufacturer of over 21,000 primary antibodies targeting the
neural circuits and to identify diseases such as neurological majority of human proteins. Our Triple A Polyclonals and PrecisA
brain disorders. Our neuroscience catalog features a wide Monoclonals antibodies are available worldwide.
range of antibodies validated in cell lines, in rodent and in
human tissues.
PTI
C SIGN CREATED BY THE HUMAN PROTEIN ATLAS
Triple A Polyclonals are developed within the prestigious Human
AL
I AND Protein Atlas project. Our antibodies are validated in all major
IN G ME
NG
M human tissues and organs and in 20 cancer tissues. Each antibody
RN is supported by over 500 staining images.
Learning and memory
OR
are complex cognitive
LEA
Y
functions, and include the
acquisition, retaining, and VALIDATED BY ENHANCED VALIDATION
retrieving of information
in the central nervous We take great care to validate our antibodies in IHC, WB, and
systems. The hippocampus ICC-IF. As an additional layer of security, we perform Enhanced
and parahippocampal Validation. By using 5 different methods, we gain the power to
region convert short-lived validate each combination of protein, sample, and application.
perceptions into
long-term memories.
EVIDENCED BY ADVANCING SCIENCE
Our antibodies are used all over the world and referenced in
1000s of scientific peer-reviewed papers.
Discover more at atlasantibodies.com
Anti-MBP monoclonal antibody Anti-NECAB1 polyclonal antibody
(AMAb91064) shows strong (HPA023629) shows strong
immunoreactivity in myelinated immunoreactivity of N-terminal
neural fibers in the rat cerebral EF-hand calcium-binding protein
cortex. Anti-GAD1 monoclonal antibody within the mouse hippocampus.
(AMAb91079) shows strong
glutamate decarboxylase-1
immunoreactivity in GABAergic
fibers in CA1 region of the rat
hippocampus.
EGENERA
OD T VELOP MENT
UR Neurodegenerative
I DE
diseases, such as
ON
NE
Amyotrophic Lateral The development of the
Sclerosis, Parkinson’s, peripheral and central
Alzheimer’s, and nervous systems begins early
Huntington’s diseases, in embryogenesis and can
occur as a result of be traced through the use of AN TIS
SU
the progressive loss of lineage antibodies specific
to each stage of neuronal
ES
HU M
structure and function
in neurons, includind the development.
death of neurons.
TT
EN IS
SU
R OD
ES
L LIN
Anti-GFAP monoclonal antibody EL
C
ES
(AMAb91033) shows strong
Anti-CHAT monoclonal antibody immunoreactivity in astrocytes
(AMAb91130) shows strong Anti-VGLUT1 monoclonal antibody
in the rat cerebellum.
immunoreactivity in the (AMAb91041) shows strong
Anti-VGAT monoclonal antibody immunoreactivity in glutamatergic
acetylcholine neurons in the (AMAb91043) shows strong
rat diagonal band of Broca. processes of the molecular and
immunoreactivity in GABAergic granular cell layers of the rat
fibers in the rat globus pallidus. cerebellum.
8/23/19 8:51 AM
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