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AMIKACIN Vial: PMA ≤29 wks. DILUENT: Intravenous: Hearing Use diluted
500mg/2ml Water for IV infusion via loss amikacin
250mg/ml 0 -7 days= injection syringe pump Reduced within 24
18mg/kg Q48hrs NSS 0.9% over 30 to 60 renal hours
Saline minutes. function Store in
8-28 days= D5W Renal fridge
15/mg/kg Q36hrs Intramuscular Failure Flush the
Draw up 0.4ml cannula
≥29= (100mg) from vial before and
15mg/kg Q24hrs after infusion
Add 19.6ml of with 0.5ml to
diluent to make a 1ml NSS
total of 20ml
Total amount =
100mg in 20ml
Final Concentration
= 5mg/ml
Aminophylline Vial: 250mg Loading dose: Diluent: Intravenous Tachyca Use
in 10ml = 8 mg/kg IV infusion over • Water for rdia Aminophylline
25mg/ml 30 minutes. injection Feeding within 24 hours
• 0.9% Sodium intolera of diluting
Maintenance dose: Chloride (NS) nce Flush the cannula
1.5 to 3 mg/kg/dose • 5% Dextrose (D5) Jittery before and after
orally, or IV slow push Seizures with 0.5ml -1ml of
every 8 to 12 hours (start Draw up 2ml NS
maintenance dose 8 to 12 Aminophylline
hours after the loading (50mg)
dose). Add 8ml to make a
total of 10ml
Maintenance dose:
5 to 10 mg/kg per dose of
caffeine citrate IV slow
push or orally every 24
hours. (Equivalent to 2.5
to 5 mg/kg caffeine base).
For intermittent or
continuous infusion,
further dilute
reconstituted drug
to a concentration
of 5 to 20 mg/mL in
compatible solution