Critical Values List Rev: 2014-06-03

Chemistry
Test Critical Values
Ammonia >110 umol/L
Carbon Dioxide <10 or >40 mmol/L
CO (Carbon Monoxide) >25 %
pH (Arterial) <7.30 or >7.65 [H+]
pH (Venous) <7.10 or >7.60 [H+]
pCO2 (Arterial) >50 mmHg
pO2 (Arterial) <50 mmHg
pO2 (Capillary) <40 mmHg
BUN: 0 – 2 yrs >65 mg/dL
BUN: >2 yrs >70 mg/dL
Calcium <7 or >12 mg/dL
CPK >1500 U/L
Creatinine: 0 - 2 yrs >4.2 mg/dL
Creatinine: 2 - 10 yrs >4.8 mg/dL
Creatinine: >10 yrs >5 mg/dL
Fe (IRON) >1800 µg/dL
Glucose: 0 - 14 yrs <40 or >300 mg/dL
Glucose: >14 yrs <46 or >500 mg/dL
Lactic Acid >5 mmol/L
LDH >3000 U/L
Magnesium <1 or >5 mg/dL
Total Bilirubin: 0 - 21 days >16 mg/dL
Phosphorus <1 mg/dL
Potassium <2.8 or >6.5 mmol/L
SGOT (AST) >1600 U/L
SGPT (ALT) >1600 U/L
Sodium <120 or >155 mmol/L

***Disclaimer*** Critical values defined in this document are based on a specific test methodology and/or specific reference
range study and are current as of the revision date. A critical value defined by a quantitative cut off range or a qualitative result
may change if a specific method or reference range is changed and this document may be out of date. Clients can check for
current testing reference ranges and methods on the Renown Test Directory website or call the laboratory directly. All critical
values are evaluated and reviewed by the laboratory section medical director. This document may become out of date.
Critical Values List Rev: 2014-06-03

Hematology / Coagulation
Test Critical Values
Hemoglobin: 0 – 14 days <10 or >20 g/dL
Hemoglobin: 14 days – 12 yrs <8 or >22 g/dL
Hemoglobin: >12 yrs <6 or >22.5 g/dL
Hematocrit: 0 – 14 days <30 or >60 %
Hematocrit: 14 days – 12 yrs <24 or >65 %
Hematocrit: >12 yrs <18 or >65 %
Platelets <50 or >1000 K/µL
WBC <2.5 or >30.0 K/µL
PT >55 sec
INR >6.5
PTT >100 sec

Toxicology
Test Critical Values
Acetominophen >50 µg/mL
Carbamazepime >14 µg/mL
Digoxin >2.5 µg/mL
Gentamicin >10 µg/mL
Phenobarbital >55 µg/mL
Phenytoin >30 µg/mL
Salicylates >300 µg/mL
Theophylline >25 µg/mL
Tobramycin >10 µg/mL
Valproic Acid >100 µg/mL
Vancomycin >50 µg/mL

***Disclaimer*** Critical values defined in this document are based on a specific test methodology and/or specific reference
range study and are current as of the revision date. A critical value defined by a quantitative cut off range or a qualitative result
may change if a specific method or reference range is changed and this document may be out of date. Clients can check for
current testing reference ranges and methods on the Renown Test Directory website or call the laboratory directly. All critical
values are evaluated and reviewed by the laboratory section medical director. This document may become out of date.
Critical Values List Rev: 2014-06-03

Microbiology / Infection Control

Test Critical Values
Acid Fast Bacillus (smear/culture) AFB seen/isolated
Antigen Tests:
RSV Positive
Rotavirus Positive
Rapid Influenzae Positive
Rapid Strep Positive
Giardia/Cryptosporidium Positive
Cryptococcal Ag Positive
HIV Screen (Exposure/Source) Positive
Blood Culture Growth
Bordetella pertussis (NP swabs/PCR) Positive
Clostridium perfringens from any culture Organism isolated
Clostridium botulinum (toxin) Positive
CSF Culture Growth
CSF Gram Stain Organism seen
CSF India Ink Yeast seen
HSV (Herpes) I/II by PCR (CSF only) HSV detected
Malaria Smear Plasmodium seen
Neisseria meningitidis from CSF or blood culture Organism isolated
Norovirus (Norwalk) Positive
Strep. pneumoniae from respiratory or blood source S.pneumo isolated
(Penicillin resistant ) (Penicillin resistant)
West Nile Virus (serum) Detected

***Disclaimer*** Critical values defined in this document are based on a specific test methodology and/or specific reference
range study and are current as of the revision date. A critical value defined by a quantitative cut off range or a qualitative result
may change if a specific method or reference range is changed and this document may be out of date. Clients can check for
current testing reference ranges and methods on the Renown Test Directory website or call the laboratory directly. All critical
values are evaluated and reviewed by the laboratory section medical director. This document may become out of date.
Critical Values List Rev: 2014-06-03

Microbiology / Infection Control

Test Critical Values
Cystic Fibrosis respiratory cultures:
Burkholderia cepacia Organism isolated
S. aureus Organism isolated
Haemphlilus influenza Organism isolated
Aspergillus sps Organism isolated
Pseudomonas aeruginosa Organism isolated
Fungal Infections:
Blastomyces dermatitidis Organism isolated
Coccidioides immitis Organism isolated
Cryptococcus neoformans Organism isolated
Histoplasma capsulatum Organism isolated
Paracoccidioides brasiliensis Organism isolated
Contact Isolation organisms:
Acinetobacter sp. Organism isolated
Clostridium difficile C.diff detected
MRSA (Meth. resist. S. aureus) MRSA isolated
VRE (Vanco resist Enterococcus sp) VRE isolated
ESBL (Extended spectrum β-lactamase producing organism) ESBL isolated

***Disclaimer*** Critical values defined in this document are based on a specific test methodology and/or specific reference
range study and are current as of the revision date. A critical value defined by a quantitative cut off range or a qualitative result
may change if a specific method or reference range is changed and this document may be out of date. Clients can check for
current testing reference ranges and methods on the Renown Test Directory website or call the laboratory directly. All critical
values are evaluated and reviewed by the laboratory section medical director. This document may become out of date.