Name: Pajaron, Edwin D

Group: 301N-2 Clinical Instructor:

DRUG STUDY
Name of Dose, Classification Mechanism of Indication Contraindication Side effect Nursing
Drugs Route, Action Responsibilities
Frequency
Antipsychotics, The activity of Contraindicated in Dizziness/low Encourage patient
Olanzapine 10mg / 2nd olanzapine is Olanzapine was patients with a blood pressure to void before
Oral / OD Generation; achieved by the initially used known upon standing taking the drug to
HS Antimanic antagonism of orally and hypersensitivity to Weight gain, help decrease
Agents multiple intramuscularly the product. May dose dependent anticholinergic
neuronal for the chronic exacerbate, High levels of effects of urinary
receptors treatment of possibly triglycerides in retention. Monitor
including the schizophrenia precipitate, the blood for elevations of
dopamine in patients over diabetes mellitus, High cholesterol temperature and
receptor D1, D2, 13 years old low white blood cell Drowsiness, differentiate
D3 and D4 in the and other count or liver dose dependent between infection
brain, the psychiatric dysfunction. Extrapyramidal and neuroleptic
serotonin disorders such Caution in symptoms (EPS), malignant
receptors as bipolar I galactosemia and dose dependent syndrome. Monitor
5HT2A, 5HT2C, disorder phenylketonuria (muscle spasms, for orthostatic
5HT3 and 5HT6, including due to excipients. jerky hypotension and
the alpha-1 mixed or manic movements, slow provide appropriate
adrenergic episodes. movements) safety measures as
receptor, the Olanzapine is Dry mouth needed.
histamine also indicated, Weakness
receptor H1 and in combination Dizziness
multiple with lithium or Accidental injury
muscarinic valproate for Insomnia
receptors. the short-term Elevated alanine
On the other treatment of aminotransferase
hand, olanzapine acute manic or (ALT) level
acts in the mixed episodes Constipation
serotonin 5HT2A associated with Indigestion
receptors in the bipolar I Elevated levels
frontal cortex in disorder in of prolactin in
a similar manner adults. the blood
than the As well, High blood sugar
reported on olanzapine is Low blood
dopamine D2 indicated, in pressure
receptors. This combination Tremor
determined with fluoxetine Weakness
effect allows for for the Restlessness
a decrease in treatment of Parkinsonism
adverse effects. episodes of reactions
depression
associated with
bipolar
disorder type 1
and treatment-
resistant
depression in
patients over
10 years old