DRUG STUDY

Drug Name Drug Action Indication and Side Effect Adverse Effect Nursing
Contraindication Consideration
Generic Name: Vitamin K helps blood Indication: Side effect:  Excessive doses of  Document the
Phytonadione (Vitamin to clot. It is essential to  For nutritional  Pain and edema Vitamin K during the giving of the
K) prevent serious supplementation to may occur at first few days of life medication to
bleeding. Babies do not prevent vitamin K injection site. may cause newborn to
Pharmacological get enough vitamin K hyperbilirubinemia; prevent an
deficiency and/or Allergic
this in turn may result
Class: Vitamins from their mothers hypoprothrombinemia. reaction such as accidental
in severe hemolytic
during pregnancy, or  Given to all newborn rash and anemia, hemoglobin, doubling of the
when they are breast infants as a single in urticaria, may leading to brain dose.
feeding. Without vastus lateralis also occur. damage or even  Observe for
vitamin K, they are at intramuscular dose of death. bleeding
risk of getting a rare 0.5 to 1 ml. (usually occurs
disorder called ‘vitamin  Prevents clotting to on second or
K deficiency bleeding’ main organs liver, third day).
(VKDB). kidney and intestine. Bleeding may
Contraindication: be seen as
 Hypersensitivity to generalized
Vitamin K ecchymoses or
bleeding from
umbilical cord,
nose or
gastrointestinal
tract.
 Observe for
jaundice,
especially in
preterm infants.
 Observe for
signs of local
inflammation.
 Apply pressure
to the injection
site to prevent
further bleeding
 Protect drug
from light.
 Drug Name Drug Action
Generic Name: This vaccine contains Indication:
Bacillus Calmette live bacteria that have
Guerin been weakened. It
works by causing the
Pharmacological body to produce its
Class: Vaccines own protection
(antibodies) against the
bacteria that causes
tuberculosis.
Contraindication:
Indication and Side Effect Adverse Effect Nursing
Contraindication Consideration
Side effect: Adverse effect:  Should only be
 swollen lymph administered
 Indicated for the nodes  Injection site intradermally;
prevention of  small red areas reactions. do not
tuberculosis since at the site of  Skin lesions distinct administer I.V.
newborn infants have a injection from the  Assess client
weak immune system  fever vaccination site. for allergic
 1st dose is given after a  blood in the reactions
few days after birth. urine.  Assess client
 2nd dose is given at the  frequent or for common
painful side effects
turn of 6 years old.
urination (e.g., redness at
 It is administered injection site or
intradermal in right  upset stomach.
fever)
deltoid for male, and in  vomiting
gluteal for female.
 Dose of 0.5 to 1ml
 BCG Vaccine should
not be administered to
HIV-infected or
immunocompromised
infants.
 BCG Vaccine is not a
vaccine for the
treatment of active
tuberculosis.
 BCG Vaccine should
not be used in infants
with severe immune
deficiency syndromes.
 Drug Name Drug Action Indication and Side Effect Adverse Effect Nursing
Contraindication Consideration
Generic Name: Active immunization Indication: Side effect: Adverse effect:  Additional
Hepatitis B Vaccine with hepatitis B  Indicated for prevention  Pain  Injection site doses may be
vaccine stimulates the of infection caused by  Soreness reactions. required for
Pharmacological immune system to all known subtypes of  Redness  Skin lesions distinct individuals with
Class: Vaccine produce anti-HBs hepatitis B virus.  Swelling at the from the a suppressed
without exposing the  1st dose shortly after injection site vaccination site. immune system.
patient to the risks of birth, 2nd dose will be at  Fever  Correct cold
active infection. 6 weeks, and 3rd dose at  Nausea chain vaccine
8 weeks storage should
 Diarrhea
 After 5 years, booster is be ensured.
given.  The injection
 Dose of 0.5 to 1ml in site batch
the vastus lateralis number and
intramuscular. expiry date
Contraindication: should be
 Hypersensitivity to recorded in the
yeast patient record.
 Severe allergic reaction  Monitor
after a previous dose or temperature.
to a vaccine component Some patients
develop a
temperature
elevation of
38.3° C (101°
F) following
vaccination that
may last 1 or 2
d.
 Drug Name Drug Action Indication and Side Effect Adverse Effect Nursing
Contraindication Consideration
Generic Name: used to treat certain eye Indication: Side effect: Adverse effect:  Cleanse the
Erythromycin infections (such as  To prevent neonatal  Redness  May cause baby’s eyes as
conjunctivitis). It is conjunctivitis and  Itching chemical needed before
Pharmacological also used to prevent ophthalmic neonatorum.  Stinging or conjunctivitis that application.
Class: macrolide certain eye infections  1-centimeter strip of burning of the last 24-48 hours:  Hold the tube in
antibiotics in newborns. It belongs ointment. eye Vision may be a horizontal
to a class of drugs Contraindication: blurred temporarily rather than a
known as macrolide  Contraindicated in vertical
antibiotics. patient with position.
Erythromycin works by hypersensitivity with  Do not touch
stopping the growth of this drug. the tip of the
bacteria.  Safety and effectiveness tube to any part
of topical drug in of the eye.
children haven’t been  Administer
established. from the inner
canthus to outer
canthus.
 Apply 0.5-1cm
ribbon in lower
conjunctival
sacs shortly
after birth.
 Observe for
irritation.