NOxBOXi

The complete Inhaled Nitric Oxide Therapy

Monitor and Delivery System
NOxBOXi™ System History
 1976 Bedfont Scientific Ltd. (Bedfont)
established in the UK
 1997 Bedfont introduces first NO Monitoring
and delivery device
 2010 Bedfont initiates development work on
NOxBOXi system with Praxair’s inputs
 2012 Bedfont introduces the NOxBOXi NO
monitoring and delivery device
 2015 Bedfont forms subsidiary NOxBOX Ltd for
critical care equipment
 2016 Praxair, Inc. acquires NOxBOX Ltd
NOxBOXi™ System History

 Over 2000 Noxbox products installed in over 50

countries around the Globe. (over 500 NOXBOXis)
 Installations in reference hospitals such as:
 Oxford University Hospital
 Oslo University Hospital
 Royal Brompton
 Kantonsspital SZ
 Shaikh Khalifa Medical City (SKMC)
 Helsinki University Hospital
 Queen Mary Hospital Hong Kong
Inhaled Nitric Oxide Administration
Inhaled NO administration demands precise monitoring and management.

Function of NOxBOXi delivery and monitoring system:

 Delivers the proper gas dose
 Injects NO in inspiratory limb
 Monitors NO, NO2, and O2 levels
Closed loop intelligent delivery system:
 Use a flow sensor to synchronize delivery with the ventilator flow
 Delivery and monitoring functions are integrated
 Any discrepancy between the programmed dose of gas and actual
dose delivered to the patient is auto-corrected by the NOxBOXi
system.
NOxBOXi and NOxMixer™ System
Benefits of Intelligent Closed Loop Nitric Oxide Delivery System
 Increased accuracy and reliability compared to legacy nitric oxide delivery systems
 Monitoring and delivery of Nitric Oxide in one system
 Easy to use and intuitive
 Efficient delivery of Nitric Oxide Gas
 Compact and lightweight
 Quick and easy to purge
 Back-up mode
 Alarm history and downloadable log files
 Therapy history
NOxBOXi and NOxMixer™ System
 CE Mark and ISO 13485 Manufacturer
 Health Canada medical device license obtained by the manufacturer in November 2015
 Both intelligent and manual delivery on same unit
 User guided interface
 Touch screen operation
 Automatic cylinder switchover
 Real time NO, NO2 and O2 monitoring
 One or two cylinder configurations (uninterrupted treatment)
 Ease of use
 Approved for transport
 Graphic Friendly Accurate
Easy Complete

Appealing

 Clear lay out

 Ease of use
 Icons and alarms
 Innovative
 Color screen

Global design and functionality appeal