Male Reproductive System

Actual Slides
 Tunica Albuginea
TESTIS
• Tunica Albuginea
- Dense Regular CT

Seminiferous Tubules
TESTIS
• Tunica Albuginea (HPO)
- Dense Regular CT Mesothelium
- Lined w/ mesothelium (simple
squamous)
SEMINIFEROUS
TUBULES
• LPO
SEMINIFEROUS
TUBULES
• Leydig cells
Seminiferous
-are large, polygonal, eosinophilic cells that
typically contain lipid droplets Tubules
- secrete testosterone

Leydig cells
SEMINIFEROUS
TUBULES
Cell Population Spermatids
1. Sertoli
• Pale-sataining
2. Spermatogenic cells
a. Spermatogonia - most numerous cell
type, adjacent to the basement
membrane
b. Spermatocytes - twice the size of the
spermatogonia, in two rows above Spermatocytes
spermatogonia
c. Spermatid - small cells adjoining the
lumen, can be early or late Spermatogonia
EPIDIDYMIS
LPO
EPIDIDYMIS
• Epididymal epithelium -
pseudostratified columnar with
stereocilia
• Smooth muscle surrounds it.
Smooth
Muscle

Epididymal epithelium
VAS DEFERENS/
DUCTUS DEFERENS
• Narrow star-shaped lumen
• w/ thick muscular layer
VAS DEFERENS/
DUCTUS DEFERENS
• Lamina propia
- Loose CT

- Muscular Layer –Smooth muscle

- Inner longitudinal
Lumen
- Middle circular
- Outer longitudinal Lamina Propia

Muscular layer
SEMINAL VESICLE
• Secrete whitish yellow viscous
material that contains fructose,
other simple sugars, amino acids,
ascorbic acid, and prostaglandins
SEMINAL VESICLE
• Lining epithelium – pseudostratified
columnar epithelium
• Lamina propia – Loose CT

Lining epithelium
Lamina propia
SEMINAL VESICLE
• Muscularis
• Inner circular
• Outer longitudinal Muscularis
 Capsule

PROSTATE GLAND Prostatic Concretions

• largest accessory sex gland Prostatic Glands

• Capsule – fibroelastic w/ smooth

muscle
• Prostatic glands - contribute to
semen; acid phosphatase, citric acid
(a nutrient for sperm), and
fibrinolysin (which keeps the semen
liquified)
• Prostatic Concretions - characteristic
feature that aids in recognition of
the prostate
PROSTATE GLAND
• Glandular epithelium –
pseudostratified columnar

• Stroma - smooth muscles

Stroma
Glandular epithelium
Female Reproductive
Actual Slides
OVARY
Cortex

Medulla
OVARY
• Germinal Epithelium – cuboidal cells
• Tunica albuginea – Dense CT
Germinal
Epithelium

Tunica
Albuginea
OVARY
1. Primordial follicles
• earliest stage of follicular development
• Squamous follicular cells
Primordial
2. Growing follicles Follicles
a. Primary – cuboidal FC
• Zona pellucida – extracellular coat of oocyte
• Stratum Granulosum – stratified epithelium
• Theca folliculi – CT cells (Interna & externa)
b. Secondary – granulosum (6-12 layers)
• Antrum – fluid Primary
3. Mature/ Graafian follicles Growing Follicle
• Contains mature secondary oocyte
 Antrum
Stratum
Ovary Granulosum
Growing follicles
a. Primary – cuboidal FC
• Zona pellucida – extracellular coat of
oocyte Theca foliculi
• Stratum Granulosum – stratified Zona Pellucida
epithelium
• Theca folliculi – CT cells (Interna &
externa)
Oocyte
b. Secondary – granulosum (6-12
layers)
• Antrum – fluid

Secondary
Growing Follicle
 Antrum
Membrana
granulosa

Ovary Theca foliculi

Mature Follicle

Corona radiata
Zona Pellucida
Oocyte

Cumulus oophorus
OVARY Corpus
• Corpus luteum
luteum
• formed after ovulation
• Luteal cells filled w/ lipid droplets
Granulosa lutein cells -progesterone
Theca lutein cells - estrogen Theca
lutein cells

Granulosa
lutein cells
UTERINE TUBE
1. Mucosa
2. Muscularis
1. Inner – circular
2. Outer - longitudinal
3. Serosa/ Adventitia
 Lining
Epithelium

UTERINE TUBE
Mucosa
• Lining epithelium
• Ciliated columnar
• Nonciliated columnar / Peg cells
• Lamina propia - CT
Lamina
propia
UTERINE TUBE
• Muscularis – smooth muscle
• Adventitia -CT

Muscularis

Adventitia
UTERUS
1. Endometrium – Mucosa
• Lining – columnar epithelium
• Functionale/Basale
2. Myometrium - muscularis
3. Perimetrium – serosa/ adventitia Endometrium

Lining Epithelium
UTERUS
Perimetrium

Myometrium
CERVIX
CERVIX
• Cervical canal – simple columnar
epithelium
Lining epithelium
CERVIX
• Ectocervix (vaginal portion) -
nonkeratinized stratified squamous
epithelium Lining
epithelium
VAGINA
1. Mucosa
• Lining – Nonkeratinized stratified
squamous epithelium Mucosa
2. Muscularis
3. Adventitia

Muscularis