Shaping Waddington’s Landscape: EVENT DETAILS

Signalling and Lineage Transitions

DATE:
in Embryonic Stem Cells Tuesday 11th February 2020

Assistant Professor William Hamilton

TIME:
Center for Stem Cell Biology, University of Copenhagen 3:00pm – 4:00pm

Bio VENUE:
How are distinct cellular identities established in development? How are time G19, Ground floor
and space measured? These are some of the most fundamental questions in 15 Innovation Walk
developmental biology. Monash University
Clayton Campus
My work aims to understand how external signals are interpreted by cells and
how they convert these signals into precisely timed responses. I use a variety HOST:
of biochemical and molecular biology approaches to manipulate and define
dynamic states of lineage potency in the hope of understanding how cells Prof Peter Currie
commit to differentiate in early development.

I obtained my PhD from The University of Edinburgh in the labs of Tilo Kunath
and Mike Tyers, where I worked on defining factors that regulate MAPK
signalling in mouse embryonic stem cells. I then joined the Brickman lab at
DanStem in Copenhagen where I expanded upon this to uncover how MAPK
signalling regulates transcription and plasticity during early stem cell
differentiation.