Drug Name Dosage & Route Action Indication Adverse Effects Contraindication Nursing Responsibility

FOLIC ACID Therapeutic Vitamin B complex Folate deficiency, Reportedly nontoxic. Folic acidalone for Assessment & Drug Effects
(VITAMIN B9, Adult: essential for macrocytic anemia, and Slight flushing and pernicious anemia or
PTEROYLGLUTAMI PO/IM/SC/IV 1 nucleoprotein synthesis megaloblastic anemias feeling of warmth other vitamin B12  Obtain a careful
C ACID) mg/d and maintenance of associated with following IV deficiency states; history of dietary
(fol'ic) Child: normal erythropoiesis. malabsorption administration. normocytic, refractory, intake and drug and
PO/IM/SC/IV 1 Acts against folic acid syndromes, alcoholism, aplastic, or undiagnosed alcohol usage prior to
mg/d deficiency that impairs primary liver disease, anemia.
Classifications start of therapy. Drugs
thymidylate synthesis inadequate dietary
Vitamin B9 reported to cause
Maintenance and results in intake, pregnancy,
folate deficiency
Adult: production of defective infancy, and childhood.
include oral
PO/IM/SC/IV DNA that leads to
contraceptives,
0.4 mg/d megaloblast formation
alcohol, barbiturates,
Child: and arrest of bone
methotrexate,
PO/IM/SC/IV <4 marrow maturation.
phenytoin, primidone,
y, 0.3 mg/d; >4
and trimethoprim.
y, 0.4 mg/d
Folate deficiency may
Infant:
also result from renal
PO/IM/SC/IV
dialysis.
0.1 mg/d
 Keep physician
informed of patient's
response to therapy.
 Monitor patients on
phenytoin for
subtherapeutic plasma
levels.