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SOFA Score
SOFA Score
SOFA Score
SOFA score
Medical diagnostics
Contents
1Medical use
2Scoring
o 2.1Respiratory system
o 2.2Nervous system
o 2.3Cardiovascular system
o 2.4Liver
o 2.5Coagulation
o 2.6Kidneys
3Quick SOFA score
4References
5External links
Medical use[edit]
The SOFA scoring system is useful in predicting the clinical outcomes of critically ill
patients.[8] According to an observational study at an Intensive Care Unit (ICU) in
Belgium, the mortality rate is at least 50% when the score is increased, regardless of
initial score, in the first 96 hours of admission, 27% to 35% if the score remains
unchanged, and less than 27% if the score is reduced. [9]
qSOFA has also been found to be poorly sensitive though decently specific for the
risk of death with SIRS possibly better for screening. [10]
Scoring[edit]
Respiratory system[edit]
≥ 400 (53.3) 0
< 400 (53.3) +1
< 300 (40) +2
< 200 (26.7) and mechanically
+3
ventilated
< 100 (13.3) and mechanically
+4
ventilated
Nervous system[edit]
Glasgow coma
SOFA score
scale
15 0
13–14 +1
10–12 +2
6–9 +3
< 6 +4
Cardiovascular system[edit]
SOFA
Mean arterial pressure OR administration of vasopressors required
score
MAP ≥ 70 mmHg 0
MAP < 70 mmHg +1
dopamine > 5 μg/kg/min OR epinephrine ≤ 0.1 μg/kg/min
+3
OR norepinephrine ≤ 0.1 μg/kg/min
dopamine > 15 μg/kg/min OR epinephrine > 0.1 μg/kg/min OR
+4
norepinephrine > 0.1 μg/kg/min
Liver[edit]
Bilirubin (mg/dl)
SOFA score
[μmol/L]
< 1.2 [< 20] 0
1.2–1.9 [20-32] +1
2.0–5.9 [33-101] +2
6.0–11.9 [102-204] +3
Coagulation[edit]
< 150 +1
< 100 +2
< 50 +3
< 20 +4
Kidneys[edit]
< 1.2 [< 110] 0
1.2–1.9 [110-170] +1
2.0–3.4 [171-299] +2
The score ranges from 0 to 3 points. The presence of 2 or more qSOFA points near
the onset of infection was associated with a greater risk of death or prolonged
intensive care unit stay. These are outcomes that are more common in infected
patients who may be septic than those with uncomplicated infection. Based upon
these findings, the Third International Consensus Definitions for Sepsis recommends
qSOFA as a simple prompt to identify infected patients outside the ICU who are likely
to be septic.[12]
References[edit]
1. ^ Singer, Mervyn; et al. (23 February 2016). "The Third International
Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)". JAMA.
p. 801. doi:10.1001/jama.2016.0287. Retrieved 24 November2018.
2. ^ Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H,
Reinhart CK, Suter PM, Thijs LG. The SOFA (Sepsis-related Organ Failure
Assessment) score to describe organ dysfunction/failure. On behalf of the Working
Group on Sepsis-Related Problems of the European Society of Intensive Care
Medicine. Intensive Care Med 1996 Jul;22(7):707-10. PMID 8844239.
3. ^ Vincent JL, de Mendonça A, Cantraine F, Moreno R, Takala J, Suter PM,
Sprung CL, Colardyn F, Blecher S. Use of the SOFA score to assess the incidence
of organ dysfunction/failure in intensive care units: results of a multicenter,
prospective study. Working group on "sepsis-related problems" of the European
Society of Intensive Care Medicine. Crit Care Med 1998 Nov;26(11):1793-
800. PMID 9824069.
4. ^ Moreno R, Vincent JL, Matos R, Mendonça A, Cantraine F, Thijs L, Takala
J, Sprung C, Antonelli M, Bruining H, Willatts S. The use of maximum SOFA score to
quantify organ dysfunction/failure in intensive care. Results of a prospective,
multicentre study. Working Group on Sepsis related Problems of the ESICM.
Intensive Care Med 1999 Jul;25(7):686-96. PMID 10470572.
5. ^ de Mendonça A, Vincent JL, Suter PM, Moreno R, Dearden NM, Antonelli
M, Takala J, Sprung C, Cantraine F. Acute renal failure in the ICU: risk factors and
outcome evaluated by the SOFA score. Intensive Care Med 2000 Jul;26(7):915-
21. PMID 10990106.
6. ^ Ferreira FL, Bota DP, Bross A, Mélot C, Vincent JL. Serial evaluation of the
SOFA score to predict outcome in critically ill patients. JAMA 2001 Oct
10;286(14):1754-8. PMID 11594901.
7. ^ "National Inpatient Hospital Costs: The Most Expensive Conditions by
Payer, 2013". www.hcup-us.ahrq.gov. Rockville, MD: Agency for Healthcare
Research and Quality. Retrieved 2017-01-07.
8. ^ Vincent, JL; de Mendonca, A; Cantraine, F; Monero, R; Takala, J; Suter,
PM; Sprung, CL (November 1998). "Use of the SOFA score to assess the incidence
of organ dysfunction/failure in intensive care units: results of a multicenter,
prospective study. Working group on "sepsis-related problems" of the European
Society of Intensive Care Medicine". Critical Care Medicine. 26 (11): 1793–
800. doi:10.1097/00003246-199811000-00016. PMID 9824069.
9. ^ Ferreira, FL; Bota, DP; Bross, A; Melot, C; Vincent, JL (10 October 2001).
"Serial evaluation of the SOFA score to predict outcome in critically ill
patients". Journal of the American Medical Association. 286 (14): 1754–
1758. doi:10.1001/jama.286.14.1754. PMID 11594901.
10. ^ Fernando, Shannon M.; Tran, Alexandre; Taljaard, Monica; Cheng, Wei;
Rochwerg, Bram; Seely, Andrew J.E.; Perry, Jeffrey J. (6 February 2018).
"Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for
Mortality in Patients With Suspected Infection". Annals of Internal Medicine. 168 (4):
266. doi:10.7326/M17-2820.
11. ^ Angus, Derek C.; Seymour, Christopher W.; Coopersmith, Craig M.;
Deutschman, Clifford S.; Klompas, Michael; Levy, Mitchell M.; Martin, Gregory S.;
Osborn, Tiffany M.; Rhee, Chanu. "A Framework for the Development and
Interpretation of Different Sepsis Definitions and Clinical Criteria". Critical Care
Medicine. 44 (3): e113–e121. doi:10.1097/ccm.0000000000001730. PMC 4765912.
12. ^ "qSOFA :: What is qSOFA?". www.qsofa.org. Retrieved 2016-05-29.
External links[edit]
Janssens U, et al. Value of SOFA (Sequential Organ Failure Assessment)
score and total maximum SOFA score in 812 patients with acute cardiovascular
disorders [abstract]. Crit Care 2001;5(Suppl 1):P225.
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