Organization: Divisions & Centers

Medicinal
Chemistry Pharmacotherapy
Molecular
& & Exp.
Pharmaceutics
Natural Therapeutics
Products

Experiential Pharmaceutical
Education Outcomes
& Practice & Policy

The Center for The Center for Institute for

Integrative Chemical Nanotechnology in Pharmacogenomics
Biology and Drug Delivery and Individualized
Drug Discovery (CNDD) Therapy
(CICBDD) (IPIT)
 Academic Programs

PharmD PhD MS

Medicinal
Chemistry Pharmacotherapy Pharmaceutical
Molecular Outcomes
& & Exp.
Pharmaceutics & Policy
Natural Therapeutics
Products

Health System
Pharmacy
 Medicinal Chemistry Molecular Pharmacotherapy
and Natural Products Pharmaceutics and Experimental
Drug Delivery Therapeutics
Synthetic Chemistry
Formulation Drug Metabolism & transport
Chemical Biology
Gene Delivery Pharmacogenomics
Bio- and Chem-informatics Nanotechnology PK/PD Modeling & Simulation
Structural Biology Material Science Clinical Trial Design
Target Discovery & Validation Bioengineering Clinical Pharmacology
Pharmaceutical
Scientists
Disease Targets Formulation and Disposition, Safety & Novel Therapies
Leads Drug Delivery Efficacy in Clinic
Novel Technologies

Center for Integrative Institute for

Center for Nanotechnology
Chemical Biology and Pharmacogenomics and
in Drug Delivery
Drug Discovery Individualized Therapy
 UNC Research Triangle Park (RTP)
Chemistry Dept.
School of Medicine
School of Public Health
Carolina Center for Genome Sciences
Lineberger Comprehensive Cancer Center
NC Translational Clinical Sciences Institute
Sheps Center Pharma/Biotech companies
Institute for Advanced Materials,
Nanoscience & Technology
UNC Hospitals

Relationships
Area Universities Pharmacy Spinoffs

Oriel Therapeutics
 Translational Biomedical Research at UNC

Partial List of Key Partners:

Depts. Chemistry, Physics, Mathematics,

& Computer Science Chemistry & Biology
- High-throughout synthesis & screening

Center for Exploratory Cheminformatics Research

Biomanufacturing Research Institute and
Technology Enterprise (BRITE) - Bioassay development
- Cheminformatics
School of Medicine
Lineberger Comprehensive
Cancer Center (LCCC)
Validated targets
Confirmed leads
CICBDD
UNC Neuroscience Center
Carolina Cardiovascular Biology Center Nanotechnology & Engineering
- Materials discovery; Nanoengineering
North Carolina Center for
Nanoscale Materials (NCCNM) - Pharmaceutics; formulations
- Biological stability; Nanotoxicology
Institute for Advanced Materials,
Nanoscience and Technology (IAM) Stable, lead formulations
UNC Institute for Nanomedicine
Carolina Center of Cancer In-Vivo Screening
Nanotechnology Excellence (CCCNE) - Biological transport; delivery
- Pharmacokinetics; ADME
Biomedical Research Imaging Center (BRIC)
Efficacious pre-clinical lead formulations
Bryson Center for Human Genetics

North Carolina Translational and Clinical

Sciences (TraCS) Institute (via NIH CTSA) Genomics & Biology
- Gene expression
Industry - Pharmacogenomics IPIT
Industry
Research Triangle
Park Link molecular genetics to efficacy