The process in which a comminuted drug or sample plant is extracted to its soluble constituents

by the slow passage of suitable solvent through a column of drug after Imbibition, drug is evenly packed
into the percolator. By the comminution the size reduction of drug usually from coarse powder to fine
powder to increase surface area, to ensure complete removal of drug, to slow down the movement of
menstruum and lastly, for uniform packing. Imbibition in which swelling of drug by absorbing
menstruum. It is allowed to stand for 4 hours in a closed container. It is done to avoid choking (difficulty
in movement), to remove air, to avoid washing out of fine particles. For packing after imbibition, drug is
evenly packed into the percolator. The cotton covered by a gauze is placed on the bottom to support the
column of drug. Then the moistened drug is placed on the filter paper. Over the moistened drug is a
filter paper place having a sand to weight on it. Then menstruum is added. Close the if menstruum is
volatile. For the maceration, after packing sufficient menstruum is added and covered with lid. When
liquid begins to drop the lower orifice is closed. Then percolator is set aside 24 hours. After 24 hours’
lower orifice is opened and menstruum is collected with a controlled speed until ¾ of menstruum is
called. Then marc is pressed to get extract which is combined with previous liquid. Then it is allowed to
stand and then it filtered. As the result, the group actually get 55 ml as the product.