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USOO5585646A
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United States Patent [191 [11] Patent Number: 5,585,646
Kossovsky et a1. [45] Date of Patent: *Dec. 17, 1996
[54] BIO-ELECTRONIC DEVICES ’ [58] Field of Search ................................ .. 257/40, 52, 53,
257/442, 72, 642, 643
[75] Inventors: Nir Kossovsky; Andrew Gelman; H.
James Hnatyszyn; Samir Rajguru, all [56] References Cited
of Los Angeles, Calif.
US. PATENT DOCUMENTS
[73] Assignee: The Regents "f the University of 5,506,420 4/1996 Kossovsky et al. .................... .. 257/40
California, Oakland, Calif.
Primary Examiner—Minhloan Tran
[*] Notice: The term of this patent shall not extend Attorney, Agent, or pirm_poms, Smith, Lande & Rose
beyond the expiration date of Pat. No.
5,506,420. [57] ABSTRACT
Improved bio-electronic devices in which a layer of a
[21] APPL N04 447,560 polyhydroxy oligomer is provided between the surface of a
[22] Filed; May 23, 1995 semiconductor material and an electronically active bio
chemical molecule which is designed to be bound to the
Related US, Application Data _ semiconductor surface to provide an electronic device. The
layer of polyhydroxy oligomer functions as a biochemical
[62] Division of Ser. No. 306,004, Sep. 14, 1994, Pat. No. stabilization layer to prevent denaturization of the electroni
5,506,420- cally active biochemical molecule.
[51] Int. Cl.6 ................................................... .. H01L 35/24
[52] US. Cl. ............................................. .. 257/40; 257/642 10 Claims, 1 Drawing Sheet
20\
/76 V / 70
\\ ' 11/14