General

Pharmaceutical Statistics is an industry-led initiative, tackling real problems in statistical

applications. The Journal publishes papers that share experiences in the practical application of
statistics within the pharmaceutical industry. It covers all aspects of pharmaceutical statistical
applications from discovery, through pre-clinical development, clinical development, post-
marketing surveillance, consumer health, production, epidemiology, and health economics.

The journal is both international and multidisciplinary. It includes high quality practical papers,
case studies and review papers.

The journal accepts high quality papers in the following formats:

● Main paper (Original article)

● Special issue paper
● Viewpoint
Viewpoint articles are short pieces that express the opinions of the authors. The ideal length
of a viewpoint is 1,000-1,500 words. Viewpoint articles should focus on a particular subject and
should not contain great technical detail. Papers that rely on technical arguments to support the
authors’ positions or opinions should be submitted as main papers
● Letter to the editor
● Teacher’s corner
● Book review
● Literature review
● Commentary
● Consultan’s forum
The aims of the Journal are to:
1. Disseminate information and practical examples of the full range of statistical methods
and statistical thinking in all stages of drug development, from discovery to production.
2. Debate the current practice and application of statistics within the pharmaceutical
industry and how this can best be developed.
3. Discuss and bring awareness to regulatory guidance documents.
 4. Provide a vehicle for communication between practitioners, researchers, educators and
policy makers concerned with the application of statistics within drug development and
5. Provide guidance and tutorials to statisticians working within the pharmaceutical area.

Note to NIH Grantees. Pursuant to NIH mandate, Wiley-Blackwell will post the accepted
version of contributions authored by NIH grant-holders to PubMedCentral upon acceptance.
This accepted version will be made publicly available 12 months after publication. For further
information, see NIH Mandate.

Manuscript Submission

All papers must be submitted via the online system. Pharmaceutical Statistics operates an
online submission and peer review system that allows authors to submit articles online and
track their progress via a web interface. Please read the remainder of these instructions to
authors and then click http://mc.manuscriptcentral.com/pst-wiley to navigate to the
Pharmaceutical Statistics online submission site. Full instructions and support are available on
the site and a user ID and password can be obtained on the first visit. If you require assistance
then click the Get Help Now link which appears at the top right of every ScholarOne
Manuscripts page.

IMPORTANT: Please check whether you already have an account in the system before trying to
create a new one. If you have reviewed or authored for the journal in the past year it is likely
that you will have had an account created.

Preprint Policy

Pharmaceutical Statistics will consider for review articles previously available as preprints.

Authors may also post the submitted version of a manuscript to a preprint server at any time.
Authors are requested to update any pre-publication versions with a link to the final published
article.

Please find the Wiley preprint policy here.

File types. Preferred formats for the text and tables of your manuscript are .doc, .rtf, .ppt, .xls.
LaTeX files may be submitted provided that a .pdf file is uploaded in addition to the source
files. Figures may be provided in .tiff or .eps format. Pharmaceutical Statistics will not accept
.pdfs as source files. Main document and Image files must be supplied in one of the preferred
document formats.

Data Protection

By submitting a manuscript to or reviewing for this publication, your name, email address, and
affiliation, and other contact details the publication might require, will be used for the regular
operations of the publication, including, when necessary, sharing with the publisher (Wiley) and
partners for production and publication. The publication and the publisher recognize the
importance of protecting the personal information collected from users in the operation of
these services, and have practices in place to ensure that steps are taken to maintain the
security, integrity, and privacy of the personal data collected and processed. You can learn
more at https://authorservices.wiley.com/statements/data-protection-policy.html.

Initial Submission

NON-LATEX USERS: Upload your manuscript files. At this stage, further source files do not need
to be uploaded.

LATEX USERS: For reviewing purposes you should upload a single .pdf that you have generated
from your source files. You must use the File Designation "Main Document" from the dropdown
box.

Revised Submission

NON-LATEX USERS: Editable source files must be uploaded at this stage. Tables must be on
separate pages after the reference list, and not be incorporated into the main text. Figures
should be uploaded as separate figure files.
LATEX USERS: When submitting your revision you must still upload a single .pdf that you have
generated from your now revised source files. You must use the File Designation "Main
Document" from the dropdown box. In addition you must upload your TeX source files. For all
your source files you must use the File Designation "Supplemental Material not for review".
Previous versions of uploaded documents must be deleted. If your manuscript is accepted for
publication we will use the files you upload to typeset your article within a totally digital
workflow.

Online Open

OnlineOpen is available to authors of primary research articles who wish to make their article
available to non-subscribers on publication, or whose funding agency requires grantees to
archive the final version of their article. With OnlineOpen, the author, the author's funding
agency, or the author's institution pays a fee to ensure that the article is made available to non-
subscribers upon publication via Wiley Online Library, as well as deposited in the funding
agency's preferred archive. For the full list of terms and conditions, see
http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms.

Any authors wishing to send their paper OnlineOpen will be required to complete the payment
form available from our website at

https://authorservices.wiley.com/bauthor/onlineopen_order.asp.

Prior to acceptance there is no requirement to inform an Editorial Office that you intend to
publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the
same way as any other article. They go through the journal's standard peer-review process and
will be accepted or rejected based on their own merit.

Copyright and Permissions

To enable the publisher to disseminate the author's work to the fullest extent, the author must
sign a license agreement transferring copyright in the article from the author to the publisher,
and complete the agreement with the article presented for publication. Submission of a
manuscript will be held to imply that it contains original unpublished work and is not being
submitted for publication elsewhere at the same time. Submitted material will not be returned
to the author, unless specifically requested.

If your paper is accepted, the author identified as the formal corresponding author for the
paper will receive an email prompting them to login into Author Services; where via the Wiley
Author Licensing Service (WALS) they will be able to complete the license agreement on behalf
of all authors on the paper.

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Article Preparation Support

Papers must be in English. Oxford English Dictionary or American spelling is acceptable,

provided usage is consistent within the manuscript.

Manuscripts that are written in English that is ambiguous or incomprehensible, in the opinion
of the Editor, will be returned to the authors with a request to resubmit once the language
issues have been improved. This policy does not imply that all papers must be written in
"perfect" English, whatever that may mean. Rather, the criterion will require that the intended
meaning of the authors must be clearly understandable, i.e., not obscured by language
problems, by referees who have agreed to review the paper.

Wiley Editing Services offers expert help with English Language Editing, as well as translation,
manuscript formatting, figure illustration, figure formatting, and graphical abstract design – so
you can submit your manuscript with confidence. Also, check out our resources for Preparing
Your Article for general guidance about writing and preparing your manuscript.  

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Presentation of papers
Manuscript style

Use a standard font of the 12-point type: Times, Helvetica, or Courier is preferred. It is not
necessary to double-line space your manuscript.

Tables must be on separate pages after the reference list, and not be incorporated into the
main text. Figures should be uploaded as separate figure files.

● During the submission process you must enter.

1. the full title
2. the short title of up to 70 characters
3. names and affiliations of all authors and
4. the full address, including email, telephone and fax of the author who is to check the
proofs.
● Include the name(s) of any sponsor(s) of the research contained in the paper, along with
grant number(s).
● Enter an abstract of no more than 250 words for all articles. Please see the guidance
below on acceptable abstract writing for PST.
● Keywords. Authors should prepare no more than 5 keywords for their manuscript.
● Appendices. Any additional material which is not essential to the article, data and tables
should be submitted as an online-only Appendix. Please upload the Appendix as
“Supplementary material not for review” on the online system.

Search Engine Optimization for Your Paper

Consult our SEO Tips for Authors page in order to maximize online discoverability for your
published research. Included are tips for making your title and abstract SEO-friendly, choosing
appropriate keywords, and promoting your research through social media.

Article Promotion Support

Wiley Editing Services offers professional video, design, and writing services to create shareable
video abstracts, infographics, conference posters, lay summaries, and research news stories for
your research – so you can help your research get the attention it deserves.

Writing Abstracts

An abstract is a concise summary of the whole paper, not just the conclusions. The abstract
should be no more than 250 words and convey the following:

1. An introduction to the work. This should be accessible by scientists in any field and
express the necessity of the experiments executed
2. Some scientific detail regarding the background to the problem
3. A summary of the main result
4. The implications of the result
5. A broader perspective of the results, once again understandable across scientific disciplines

It is crucial that the abstract conveys the importance and novelty of the work and be
understandable without reference to the rest of the manuscript to a multidisciplinary audience.
Abstracts should not contain any citation to other published works.

Mentoring for First Time Authors

Authors who have not submitted a paper to a journal before are encouraged to contact the
Editors who can arrange for a mentor to support a first submission to Pharmaceutical Statistics.
Mentors will not be able to provide the detailed scientific scrutiny of peer review but can
answer questions about the submission process and review. They can also answer questions
about what makes an article interesting and clear to a scientific reader.

Reference Style
AMA Reference style

References: All references should be numbered consecutively in order of appearance and

should be as complete as possible. In text citations should cite references in consecutive order
using Arabic superscript numerals. Sample references follow:

Journal article:

1. King VM, Armstrong DM, Apps R, Trott JR. Numerical aspects of pontine, lateral reticular, and
inferior olivary projections to two paravermal cortical zones of the cat cerebellum. J Comp
Neurol 1998;390:537-551.

Book:

2. Voet D, Voet JG. Biochemistry. New York: John Wiley & Sons; 1990. 1223 p.

Please note that journal title abbreviations should conform to the practices of Chemical
Abstracts. For more information about AMA reference style - AMA Manual of Style

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Citing Early View Articles

To include the DOI* in a citation to an article, simply append it to the reference as in the
following example:

Weaver PJ, Laures AM-F, Wolff J-C. Investigation of the advanced functionalities of a hybrid
quadrupole orthogonal acceleration time-of-flight mass spectrometer. Rapid Commun Mass
Spectrom 2007: DOI: 10.1002/RCM.21464.

To link to an article from the author’s homepage, take the DOI (digital object identifier) and
append it to "http://dx.doi.org/" as per following example:
DOI:10.1002/pst.20941, becomes http://dx.doi.org/10.1002/pst.20941.

*The Digital Object Identifier (DOI) is an identification system for intellectual property in the
digital environment. Developed by the International DOI Foundation on behalf of the publishing
industry, its goals are to provide a framework for managing intellectual content, link customers
with publishers, facilitate electronic commerce, and enable automated copyright management.

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Illustrations

Upload each figure as a separate file in either .tiff or .eps format, with the figure number and
the top of the figure indicated. Compound figures e.g. 1a, b, c should be uploaded as one figure.
Tints are not acceptable. Lettering must be of a reasonable size that would still be clearly legible
upon reduction, and consistent within each figure and set of figures. Where a key to symbols is
required, please include this in the artwork itself, not in the figure legend. All illustrations must
be supplied at the correct resolution:

● Black and white and colour photos - 300 dpi

● Graphs, drawings, etc - 800 dpi preferred; 600 dpi minimum
● Combinations of photos and drawings (black and white and colour) - 500 dpi

Tables should be part of the the main document and should be placed after the references. If
the table is created in excel the file should be uploaded separately.

Colour policy

Illustrations will be reproduced in colour online free of charge.

Guidelines for Cover Submissions

If you would like to send suggestions for artwork related to your manuscript to be considered to
appear on the cover of the journal, please follow these general guidelines.
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Supporting Information

Supporting Information can be a useful way for an author to include important but ancillary
information with the online version of an article. Examples of Supporting Information include
additional tables, data sets, figures, movie files, audio clips, 3D structures, and other related
nonessential multimedia files. Supporting Information should be cited within the article text,
and a descriptive legend should be included. It is published as supplied by the author, and a
proof is not made available prior to publication; for these reasons, authors should provide any
Supporting Information in the desired final format.

For further information on recommended file types and requirements for submission, please
visit: http://authorservices.wiley.com/bauthor/suppinfo.asp

Data Policy

PST expects that data supporting the results in the paper will be archived in an appropriate
public repository. Whenever possible the scripts and other artefacts used to generate the
analyses presented in the paper should also be publically archived. Exceptions may be granted
at the discretion of the editor for sensitive information such as human subject data or the
location of endangered species. Authors are expected to provide a data accessibility statement,
including a link to the repository they have used, to accompany their paper.

Visit re3data.org or fairsharing.org to help identify registered and certified data repositories

relevant to your subject area.

Wiley journals require data to be cited in the same way as article, book, and web citations and
authors are required to include data citations as part of their reference list.

More information about the Data Sharing Policy can be found here.

Article Formats Published in PST

PST publishes research papers, book reviews, literature reviews, software reviews, viewpoint
articles, consultants’ forum articles, new starters and teachers’ corner articles.

Viewpoint articles are short pieces that express the opinions of the authors. The ideal length of
a viewpoint is 1,000-1,500 words. Viewpoint articles should focus on a particular subject and
should not contain great technical detail. Papers that rely on technical arguments to support
the authors’ positions or opinions should be submitted as main papers. 

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Publication Ethics

Wiley's Best Practice Guidleines on Publishing Ethics are now available. The aim for these
guidelines remains to support all those involved in scholarly publishing with a summary of best
practice guidance from leading organizations around the world. Our guidelines are written for
societies, editors, authors, librarians, students, funders, corporations, and journalists.

Further Information

For accepted manuscripts the publisher will supply proofs to the submitting author prior to
publication. This stage is to be used only to correct errors that may have been introduced
during the production process. Prompt return of the corrected proofs, preferably within two
days of receipt, will minimise the risk of the paper being held over to a later issue.

Free access to the final PDF offprint or your article will be available via Author Services only.
Please therefore sign up for Author Services if you would like to access your article PDF offprint
and enjoy the many other benefits the service offers. There is no page charge to authors.

To purchase reprints in smaller quantities, please visit

http://olabout.wiley.com/WileyCDA/Section/id-404512.html. Restrictions apply to the use of

reprints – if you have a specific query, please contact permissionsuk@wiley.com.
Corresponding authors are invited to inform their co-authors of the reprint options available
Manuscript accepted for publication? If so, check out our suite of tools and services for authors
and sign up for:

• Article Tracking

• E-mail Publication Alerts

• Personalization Tools

Potential threat to security

Where a reviewer is concerned that an article might include information that could be a threat
to security then the Editor will treat the article as possible DURC (dual use research of concern)
and may consult a specialist reviewer.  Their advice will be taken into account by the Editor in
making any final decision on publication.