Contact Lens & Anterior Eye 41S (2018) S38–S46
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Contact Lens & Anterior Eye
journal homepage: www.elsevier.com/locate/clae
2016 BCLA/NCC Papers and Poster Abstracts
Predicting success with multifocal contact
lenses
Ahmed Sivardeen, Deborah Laughton, James
Wolffsohn
Purpose: To determine the utility of a range of clinical and
non-clinical indicators to aid the initial selection of the optimum
presbyopic contact lens. In addition, to assess whether lens pref-
erence was influenced by the visual performance compared to the
other designs trialled (intra-subject) or compared to patients who
preferred other designs (inter-subject).
Methods: A double-masked randomised crossover trial of Air
Optix Aqua multifocal, PureVision 2 for Presbyopia, Acuvue OASYS
for Presbyopia, Biofinity multifocal and monovision was conducted
on 35 presbyopes (54.3 ± 6.2 years). Participant lifestyle, person-
ality (assessed subjectively the patient’s representation of his/her
view of his/her personality in a linear scale from 0-easy going to
10-a perfectionist) and aberrometry were assessed prior to lens
fitting. After 4 weeks of wear, high and low contrast visual acuity
(VA) under photopic and mesopic conditions, reading speed, Near
Activity Visual Questionnaire (NAVQ) rating, subjective quality-of-
vision scoring, defocus curves, stereopsis, halometry, aberrometry
and ocular physiology were quantified.
Results: After trialling all the lenses, preference was mixed
(n = 12 Biofinity, n = 10 monovision, n = 7 Purevision, n = 4 Air Optix
Aqua, n = 2 Oasys). Lens preference was not dependent on per-
sonality (F = 1.182, p = 0.323) or the hours spent working at near
(p = 0.535) or intermediate (p = 0.759) daily. No intersubject or
strong intrasubject relationships emerged between lens preference
and reading speed, NAVQ rating, halo size, aberrometry or ocular
physiology (p > 0.05).
Conclusions: Participant lifestyle and personality, ocular optics,
contact lens visual performance and ocular physiology provided
poor indicators of the preferred lens type after 4 weeks of wear. This
is confounded by the wide range of task visual demands of presby-
opes and the limited optical differences between current multifocal
contact lens designs. The influence of the near addition on the lens
preference would be an interesting area for further research.
https://doi.org/10.1016/j.clae.2018.04.053
1367-0484/
Clinical outcomes of a povidone-iodine based
contact lens cleaning solution for soft contact
lens wearers
Mark Willcox, Jacqueline Tan, Katherine Wong,
Kathlene Watt, Ajay Vijay, Fiona Stapleton
Purpose: To evaluate the safety and efficacy of a povidone-
iodine (PI) based contact lens (CL) cleaning and disinfecting solution
during daily wear of frequent replacement soft CL wearers.
Methods: A prospective, single centre, open label clinical trial.
At Baseline, assessments were conducted for participants’ habitual
lens care product. Participants were dispensed with the PI system
for use with a new pair of their habitual CLs upon daily removal.
Subjective responses and anterior ocular health assessments were
conducted at 1 month and 3 months. Results at 1 month and 3
months (with PI) were compared with baseline using one-way
ANOVA.
Results: Forty soft CL wearers (34 silicone hydrogel and 6 hydro-
gel) with average age 30 ± 13 years completed the study. Four used
peroxide and 36 used multi-purpose disinfecting solutions at base-
line. One case of asymptomatic corneal infiltrates (CIE) occurred at
3 months; this was the only lens-related adverse event. The overall
incidence rate of CIEs was 1 per 100 participant-months, and with
senofilcon A (most common SiHy lens; n = 18) was zero. Corneal
staining extent was lower at 3 months compared to baseline in each
eye (0.39 ± 0.47 vs. 0.96 ± 0.89, p = 0.002; 0.46 ± 0.51 vs. 1.10 ± 1.01,
p = 0.001 for right or left eyes respectively). No cases of solution-
induced corneal staining were observed. No significant differences
were found in subjective comfort or vision, or for objective assess-
ments of bulbar and limbal redness, and upper palpebral roughness
and redness (p > 0.05) between baseline and the follow-up visits.
Conclusions: PI reduced the level of corneal staining at 3
months, and only one CIE was observed over the course of the study.
This study demonstrated that PI was compatible with a variety of
commercially available frequent replacement soft CLs.
https://doi.org/10.1016/j.clae.2018.04.054