DRUG STUDY for Postpartum Depression

Drug Name Mechanism of Action Adverse Reaction Nurse Intervention

Generic name: The mechanism of action of o Headache o Be alert for adverse reaction of drug
Sertraline sertraline is presumed to be linked o Nervousness interaction.
to its inhibition of CNS neuronal o Anxiety o Be alert in risk of the patient’s
Brand Name: uptake of serotonin (5HT). Studies o Thirst suicidal thoughts.
Zoloft at clinically relevant doses in man o Monitor patient’s feelings.
o Chest pain
have demonstrated that sertraline o Use lower dose in elderly patients
Dosage:
o Nausea
blocks the uptake of serotonin into
25 mg or 50 mg per day is the o Dizziness and with hepatic or renal impairment.
human platelets.
initial therapeutic dosage. o Drowsiness o For pregnant women monitor cervical
o Dry mouth effacement and dilatation.
Onset of Action: o Loss of appetite o Report rash, mania, seizures,
7 days o Increased sweating edema, difficulty breathing,
o Diarrhea increased depression, thoughts of
Classification : suicide.
Antidepressant o Upset stomach
o Trouble in sleeping