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Insulin – lowers glucose levels by inhibiting glycogenolysis and gluconeogenesis in liver and by stimulating glucose uptake into

muscle and adipose tissue


 Glucagon –stimulates hepatic glycogenolysis and gluconeogenesis
5 Epinephrine - directly antagonize glucose uptake by muscle or fat (not Glucagon)

Long arm of Chromosome 17- synthesis of GH

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In GH deficiency, IGF-1 levels are low but not IGF-2
In excess GH, IGF-1 levels are high but not IGF-2

LEPRECHAUNISM – result of a defect in Insulin receptor


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Overproduction = increased RMR and NEAT
Deficiency = decreased RMR and NEAT

All of Db (def. Leptin) mouse partner will decrease in weight.


20 More leptin= less appetite

11B-HSD2 - renal IRREVERSIBLE


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Androstenedione  17B-hydroxysteroid dehydrogenase =Testosterone

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