Immobilized Biomolecules in Analysis: A Practical

Approach / A. E. G. Cass, Tony Cass / 1998

Oxford University Press, 1998 / 216 pages / 0199636362,

9780199636365 / A. E. G. Cass, Tony Cass / 1998 / Immobilized
Biomolecules in Analysis: A Practical Approach / Biomolecules and cells
are critical components of biosensors and biomaterials, but in order to
function in an artificial environment, they must be immobilized in a
manner that does not affect their interaction with target analytes.
Biosensors demonstrate that we can harness the incredible functions of
living molecules and cells for our own purposes and are therefore at the
forefront of technology. Moreover the applications of immobilized
biomolecules and cells are expected to expand far beyond biosensor
applications and indeed are already used for pharmaceutical production
and testing. Biomaterials will become increasing common as they are
being developed into toxic filters, artificial organs, and even silicon
chips. This book provides a selection of methods for the immobilization
of biomolecules and cells on a variety of surface with different
geometries and chemistries so that they retain their function and
guidelines on which method to use. Also included are the
analyticaltechniques to measure the functionality of immobilized
biomolecules. All the protocols have been tried and validated by the
authors. Immobilized Biomolecules in Analysis: A Practical Approach is
an invaluable guide to all researchers in the fields of biosensors and
biomaterials. Research in biosensors is carried out in a wide variety of
fields including biochemistry, chemistry, engineering, laboratory
medicine, environmental and defence research. The protocols are written
so that an extensive prior knowledge of biochemistry is not required to
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Expert laboratorians update the classic bioconjugation methods and
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