Tabel 3.

Tabel Data Hasil Disolusi Furosemid Tablet Dagang

No Waktu(menit) Absorbansi Konsentrasi(ppm)
1 0 0,000 0,0000
2 5 0,199 4,6692
3 10 0,185 4,2498
4 20 0,204 4,8102
5 30 0,191 4,4243
6 40 0,191 4,4168
7 50 0,191 4,4131
8 60 0,183 4,1867

Perhitungan Uji Disolusi Furosemid Tablet Dagang

t=0 -> 0 = 0,032931216 x + 0,045296302

X = 0,0
t=5 -> 0,199 = 0,032931216 x + 0,045296302
X = 4,667416411
t=10 -> 0,106 = 0,032931216 x + 0,045296302
X = 4,242287665
t=20 -> 0,140 = 0,032931216 x + 0,045296302
X = 4,819248035
t=30 -> 0,136 =0,032931216 x + 0,045296302
X = 4,424485813
t=40 -> 0,145 = 0,032931216 x + 0,045296302
X = 4,424485813
t=50 -> 0,143 = 0,032931216 x + 0,045296302
X = 4,424485813
t=60 -> 0,140 = 0,032931216 x + 0,045296302
X = 4,181555215

WAKTU KONSENTRASI
5 4,667416411
10 4,242287865
20 4,819248035
30 4,424485813
40 4,424485813
 50 4,424485813
60 4,181555216

Tabel 4.Tabel Data Hasil Disolusi Furosemid Tablet Dagang

N t A C FP CxFP CxFP Faktor C obat %
o (pp (ppm) dalam Pe(+) yang Kumulatif
m) 900ml dilepas
(ppm)
1 5 0,199 4,66 50 233,3 21009 233,3 210267 525,66779
7416 70020 3,738 70820 ,1099 9
41 6 5 6
2 10 0,185 4,24 50 212,1 1909, 445,4 191348 478,37109
2287 14993 03954 85213 ,4392 8
865 3 9
3 20 0,204 4,81 50 240,9 21656 686,4 217552 543,88152
9248 62401 6,161 47015 ,6092 3
635 8 6 7
4 30 0,191 4,42 50 221,2 19910 907,6 200009 500,88152
4485 29290 1,861 71906 ,5395 3
813 7 6 4
5 40 0,191 4,42 50 221,2 19910 1128, 200230 500,57689
4485 29290 1,861 89619 ,7578 45
813 7 6 7
6 50 0,191 4,42 50 221,2 19910 1350, 200451 500,12995
4485 29290 1,861 12048 ,9821 53
813 7 6 8
7 60 0,183 4,18 50 209,0 18816 1559, 189729 474,32295
1555 77700 9,984 19824 ,1829 73
216 8 7

Perhitungan Data Disolusi Furosemid Tablet Dagang

- C x FP (ppm)
t=5 -> 4,667416411 x 50 = 233,3700206
t=10 -> 4,242287865 x 50 = 212,1149933
t=20 -> 4,819248035 x 50 = 240,9624018
t=30 -> 4,424485813 x 50 = 221,2292907
t=40 -> 4,424485813 x 50 = 221,2292907
t=50 -> 4,424485813 x 50 = 221,2292907
t=60 -> 4,181555216 x 50 = 209,0777008
- C x FP x 900 mL
t=5 -> 233,3700206 x 900 = 210093,7385
t=10 -> 212,1149933 x 900 = 1909,03954
t=20 -> 240,9624018 x 900 = 216566,1616
t=30 -> 221,2292907 x 900 = 199101,8616
t=40 -> 221,2292907 x 900 = 199101,8616
t=50 -> 221,2292907 x 900 = 199101,8616
t=60 -> 209,0777008 x 900 = 188169,9847

- Faktor Penambahan
t=5 -> 0 + 233,3700206 = 233,3700206
t=10 -> 233,3700206 + 212,1149933 = 445,4852139
t=20 -> 445,4852139 + 240,9624018 = 686,4470157
t=30 -> 686,4470157 + 1128,896197 = 907,6719064
t=40 -> 907,6719064 + 224,2907 = 1128,896197
t=50 -> 1128,896197 + 21,2242907 = 1350,120488
t=60 -> 1350,120488 + 1559, 198249 = 1559,19824

- C obat yang dilepas

t=5 -> 210093,7385 + 233,3700206 = 210267,1099
t=10 -> 1909,03954 + 445,4852139 = 191348,4392
t=20 -> 216566,1616 + 686,4470157 = 217552,6092
t=30 -> 199101,8616 + 907,6719064 = 200009,5395
t=40 -> 199101,8616 + 1128,896197 = 200230,7578
t=50 -> 199101,8616 + 1350,120488 = 200451,9821
t=60 -> 188169,9847+ 1559,19824 = 189729,1829

- % kumulatif

210267,1099
t=5 -> x 100 % = 525,667799 %
4000
191348,4392
t=10 -> x 100 % = 478,371098 %
4000
217552,6092
t=20 -> x 100 % =543,881523%
4000
200009,5395
t=30 -> x 100 % = 500,881523 %
4000
200230,7578
t=40 -> x 100 % = 500,5768945 %
4000
200451,9821
t=50 -> x 100 % = 500,1299553 %
4000
 189729,1829
t=60 -> x 100 % = 474,3229573 %
4000