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Clinical Research

Cost-effectiveness of Different Post-retained


Restorations
Falk Schwendicke, PhD,* and Michael Stolpe, Dr†

Abstract
Objectives: Dentists can choose between metal and
fiber post systems to provide post-retained restorations.
The risk of tooth loss and other complications differs be-
T o restore endodonti-
cally treated teeth with
limited coronal tooth hard
Significance
We found preformed metal post-retained restora-
tions to be least costly, whereas glass fiber post-
tween different post systems, as do the initial treatment tissue, post-retained resto-
retained restorations were moderately more
costs. We aimed to assess the cost-effectiveness of (1) rations (crowns) are often
expensive but also more effective. Clinical
cast metal (MC), (2) preformed metal (MP), (3) glass fiber required. For such post-
decision-making should consider both the initial
(GF), and (4) carbon fiber (CF) post-retained restorations. retained restorations, cli-
treatment costs and also costs associated with
Methods: A mixed public-private payer’s perspective nicians can use metal posts
possible long-term complications.
within German healthcare was taken. Risks of complica- or non-metal fiber posts.
tions were extracted from systematic reviews. Costs were Metal posts can either be
estimated by using fee items and 2016 material costs. cast, often as post-core casts, or preformed, with the core being directly placed after
A Markov model was constructed to follow up an cementation of the post. Fiber posts are usually preformed and contain carbon, quartz,
endodontically treated molar receiving a post-retained or glass fibers, which are embedded in an epoxy or methacrylate matrix. These are
crown in an initially 50-year-old patient during his life- usually adhesively luted, with the core being directly placed. In contrast to metal posts,
time. Monte Carlo microsimulations were performed to the elastic modulus of fiber posts is similar to dentin (1, 2), which should assist to
assess lifetime costs and tooth retention time. Results: distribute the stress under load, reducing the risk for vertical root fracture (3–6).
MPs were least costly (692V), retaining teeth for In contrast to the results from in vitro studies, clinical studies found the risk of such
26.7 years. GFs were more costly (745V), retaining teeth fatal complications to be similar in teeth with metal versus fiber post-retained restorations;
for 27.6 years. MCs were minimally more effective but however, risks seem to differ in different types of metal and fiber posts (7). Moreover, the
also more costly than GFs (774V). CFs were less effective risk of non-fatal complications might be different between different post types too (7).
and most expensive (825V, 26.7 years). For payers At present, there is ambiguity with regard to the suitability of different post systems, with
willing to invest more than 60V per tooth retention no clear guidance being available for clinicians as to which system is most appropriate (8).
year, GF was cost-effective. Payers willing to invest an One aspect that has so far not been assessed when comparing different post-retained
additional 670V found MC to be cost-effective. These restorations is cost-effectiveness: The placement of different posts involves different
findings were found robust in sensitivity analyses. Con- efforts; for laboratorial manufacturing or adhesive luting, these differences will lead to
clusions: For payers not willing to invest additional different initial treatment costs. Moreover, different risks will generate different long-
money for longer tooth retention, MP seemed most suit- term costs for mending complications such as recementation, re-restoration, or replace-
able to retain restorations. For payers with additional will- ment. Assessing such long-term consequences of treatments and retreatments is complex.
ingness to pay, GF seemed suitable, retaining teeth for The present study aimed to assess the cost-effectiveness of different post-retained
longer. MC was only cost-effective under very high will- crowns. To reflect the discussed long-term aspects, a model-based approach was
ingness to pay. CF is not recommendable on the basis chosen. The findings of this study are relevant for payers, clinicians, patients, and
of their cost-effectiveness. (J Endod 2017;43:709–714) healthcare researchers alike because they might assist to guide clinical and non-
clinical (health services) decision-making as well as the conduct of future studies.
Key Words
Computer modelling, dental care, fiber posts, health Methods
economics, Markov model, prosthetics Setting, Perspective, Population, Horizon
This study adopted a mixed public-private payer perspective in the context of
German healthcare. We modeled a population of initially 50-year-old men with a molar
tooth that had completed endodontic treatment of a vital, painless pulp with 3 root
canals. Molars were assumed to require a post-retained crown and were followed

From the *Department of Operative and Preventive Dentistry, Charite – Universit€atsmedizin Berlin, Berlin, Germany; and †Kiel Institute for the World Economy, Kiel,
Germany.
Address requests for reprints to Dr Falk Schwendicke, Department of Operative and Preventive Dentistry, Charite – Universit€atsmedizin Berlin, Campus Benjamin
Franklin, Aßmannshauser Str. 4-6, 14197 Berlin, Germany. E-mail address: falk.schwendicke@gmail.com
0099-2399/$ - see front matter
Copyright ª 2017 American Association of Endodontists.
http://dx.doi.org/10.1016/j.joen.2017.01.002

JOE — Volume 43, Number 5, May 2017 Cost-effectiveness of Different Endodontic Posts 709
Clinical Research
during the patient’s lifetime (TreeAge Pro 2013; TreeAge Software, risks of endodontic complications were derived from existing studies
Williamstown, MA), which was determined by age and gender. in the field and systematic reviews (Table 1). Teeth that had experienced
All cost-effectiveness evaluations were performed per 1 molar to orthograde retreatment were treated surgically in case of further end-
avoid clustering and the associated issues of correlation and to increase odontic complications; those that had received surgical retreatment
the ease of interpretation of our findings. Note that for this study, we did were extracted in case of further endodontic complications. We varied
not specify any further factors that influence the survival of post-retained the proportion of endodontic complications being mended surgically or
teeth such as root canal and post shape, post preparation type, or non-surgically between 0% and 100%. In an additional analysis, we
specific cementation or adhesive luting materials, etc. assumed teeth with adhesively placed posts to not receive orthograde
but only surgical retreatment, whereas those with metal posts were
Comparators all first non-surgically retreated in case of complications.
We compared 4 strategies: Restorative complications (Table 1) were mended by recementation
of the crown or renewal of the crown (involving the renewal of the post and
1. A cast metal post-retained crown (MC) core too). We assumed 60% of such complications to be decementations,
2. A preformed (passive) metal post-retained crown (MP) ie, requiring recementation, and 40% to require renewal of the crown.
3. A glass fiber post-retained crown (GF) In case of teeth that needed removal, their replacement by using
4. A carbon fiber post-retained crown (CF) implant-supported single crowns was modeled. We assumed 50% of
Metal posts were assumed to be cemented conventionally, whereas teeth to be replaced in the base-case scenario; this was varied to account
fiber posts were assumed to be luted adhesively. The placed crown was for heterogeneity (of patients, etc.). Implant-supported crowns were
assumed to be a full non-precious metal crown, as is standard under the assumed to be prone for complications from the implant (peri-implan-
assumptions of the statutory insurance in Germany for molars. titis, implant fracture), which we assumed to lead to implant removal
and in 50% of the cases renewal of the implant, and complications of
Model and Assumptions the crown (decementation, fracture, etc), which we assumed to lead
to crown replacement or recementation. Risks of complications of
Molars were assumed to experience fatal and non-fatal complica-
implant-supported crowns were derived from a systematic review (13).
tions, the risks of which were extracted from a recent systematic review
The constructed model is shown in Figure 1. Model validation was
for the different comparators (7). Fatal complications were those leading
performed internally by varying key parameters to check their impact
to the tooth being extracted (mainly root fractures). Non-fatal complica-
on the results, by evaluating different model structures, and by perform-
tions were those needing retreatments, including endodontic complica-
ing sensitivity analyses.
tions, decementation or crown dislodgments, fractures, secondary
caries, etc. The risk of complications and the probabilities of allocation
to different treatments mending these complications are given in Table 1. Health Outcomes and Measurement of Effectiveness
Endodontic complications were assumed to be mended by The health outcome was tooth retention years, ie, the mean time a
nonsurgical (orthograde) or surgical retreatment (apisectomy). The tooth was retained in a patient’s mouth. Transition probabilities to allow

TABLE 1. Parameters Used for Effectiveness Estimation


Transition
probability Triangular Allocation
Health state Reference per year distribution* Allocation to probability
Fatal failures
MC Figueiredo et al, 2015 (7) 0.0034 0.1, 1.0, 2.2 Removal 0.50
MP 0.0055 0.8, 1.0, 1.2 Removal and replacement 0.50†
GF 0.0036 0.2, 1.0, 1.8
CF 0.0057 0.6, 1.0, 1.4
Non-fatal restorative
failures‡
MC Figueiredo et al, 2015 (7) 0.022 0.3, 1.0, 1.7 Renewal post-crown 0.40
MP 0.013 0.7, 1.0, 1.3 Recementation post-crown 0.60
GF 0.014 0.1, 1.0, 2.3
CF 0.023 0.7, 1.0, 1.3
Non-fatal endodontic
complications
RCT Ricucci et al, 2011 (9); 0.0232a0.823 — Non-surgical re-RCT 0.50
Schwendicke et al, 2014 (10) Surgical re-RCT 0.50†
Non-surgical re-RCT Ng et al, 2008 (11) 0.059 0.3, 1.0, 2.0 Surgical re-RCT Extraction 0.80†
0.20
Surgical re-RCT Torabinejad et al, 2009 (12) 0.080 0.5, 1.0, 2.0 Extraction 1.00
Implant complications Jung et al, 2012 (13) 0.032 0.5, 1.0, 1.7 Renew Remove 0.5
0.5
Implant crown Jung et al, 2012 (13) 0.047 0.6, 1.0, 1.8 Renewal Recementation 0.4
complications 0.6
RCT, root canal therapy.
*Distributions were used to express uncertainty, with triangular distributions being used for random sampling during probabilistic sensitivity analyses.

Were varied in sensitivity analyses.

Note that we modeled endodontic complications separately from the remaining complications outlined as ‘‘non-fatal’’ in the systematic review informing this study (7) to allow modeling of follow-up endodontic
complications. Note that this will have increased the overall risk of non-fatal complications, without any difference between groups.

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Clinical Research

Figure 1. Transition diagram. Fatal or non-fatal complications could occur (see Table 1 for details). Fatal complications led to removal, whereas non-fatal compli-
cations could be endodontic or restorative ones, which could be mended via a range of options but did not lead to tooth loss. However, it should be noted that in the
follow-up states to these non-fatal complications, tooth loss was possible (ie, after non-surgical re-root canal treatment). For implants, implant and crown complications
were modeled. For the purpose of illustrating the application of the transition probabilities shown in Table 1, we also depict these probabilities for MC (p).

teeth to move from one health state to another (ie, risks of complica- covered at all. Costs for treatments partially or not at all covered by
tions and associated retreatments) were estimated as described above the public insurance are estimated by using fee items from the private
and are summarized in Table 1. catalogue GOZ. Publicly insured patients pay the additional costs out of
their own pocket (in case they have private additional insurance, these
costs might be reimbursed). For GOZ, factoring of item points is com-
Resources and Costs mon to determine prices, which allows individualizing of fees. The pre-
This study modeled a publicly insured patient by using a mixed sent analysis used the standard multiplication factor (2.3).
public-private payer perspective, as is most common in Germany. Calculating costs by using average national multiplication factors
Cost calculations were based on the German public and private dental (17) has not been found to greatly impact on cost-effectiveness (18).
fee catalogues, BEMA (Bewertungsmaßstab) and GOZ (Geb€uhrenord- A small proportion of German patients are not members of the
nung f€ur Zahn€arzte) (14, 15). German dentists estimate their costs public insurance; for them, all costs are estimated by using fees from
by using fee items; this estimation is the basis for claims for the private item catalogue. Our calculations do not fully apply to these
reimbursement from the patient himself or his insurer. Most patients patients; however, analyses using cost estimations for these patients
are publicly insured (16), ie, fee items are drawn from the public cata- have been found to yield only limitedly different results compared
logue BEMA for the majority of treatments (like most conservative or with those yielded for publicly insured patients (18, 19). Because of
surgical treatments). Prosthetic treatments are only partially covered; the lack of primary data, opportunity costs of patients’ time in
non-surgical re-root canal treatment and implants are not usually treatment were not accounted for.

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TABLE 2. Cost Estimation per Treatment Complex were ranked according to their costs, and incremental cost-effectiveness
ratios (ICERs) were exemplarily used to express cost differences per
Course of treatment Costs (V)
gained or lost effectiveness. Positive ICERs indicate additional costs
MC 488.25 per additional effectiveness, whereas negative ICERs indicate additional
MP 434.49
Core crown with GF 491.21
costs per effectiveness loss. Strategies that were more costly and less
Core crown with CF 489.22 effective were dominated; those that were more costly but also more
Recementation of a crown 54.29 effective were undominated.
Orthograde re-RCT 526.78 To introduce parameter uncertainty, we randomly sampled transi-
Apical surgery 154.63 tion probabilities from a triangular distribution of parameters (23). By us-
Tooth/implant removal 67.41
Implant insertion 958.40 ing estimates for costs (c, in euros) and effectiveness (e, in years), the net
Implant crown 345.23 benefit of each strategy combination was calculated by using the formula:
Costs were calculated by quantification of item fees from public or private item catalogues. For net benefit ¼ l  De  Dc;
further details see Appendix, Schwendicke and Stolpe (10), and Schwendicke et al (15).
with l denoting the ceiling threshold of willingness to pay, ie, the addi-
Additional fee items, laboratory, and material costs were included tional costs a decision maker is willing to bear for gaining an additional
in our cost estimations. Laboratory costs were estimated by using fee unit of effectiveness (24). If l > Dc/De, an alternative intervention is
items as well, as outlined elsewhere (20). For materials, 2016 market considered more cost-effective than the comparator despite possibly
prices for exemplary materials were used (Appendix is available online being more costly (23). We used the net-benefit approach to calculate
at www.jendodon.com). the probability of a strategy being cost-effective for payers with different
willingness-to-pay ceiling thresholds. In addition, a number of univar-
iate sensitivity analyses were performed to explore the impact of uncer-
Discounting, Currency, and Price Data tainty and heterogeneity.
All costs were calculated in 2016 euros, and future costs and effec-
tiveness were discounted at 3% per annum (21), discounting accounts for
opportunities forgone if spending money now instead of later or gaining Results
health benefits later instead of now. Discounting rates were varied Study Parameters
between 0% and 5% to explore the impact of higher or lower discounting. Effectiveness parameters can be found in Table 1. Cost estimates
for different procedures can be found in Table 2, with details on unit
Analytical Methods costs and quantities laid out in Appendix (available online at www.
Monte Carlo microsimulations were performed for analysis, with jendodon.com).
1000 independent individual molars being followed during the average
expected lifetime of patients (which was 29 years) (22) in annual Base-case Scenario
cycles. Different lifetimes were modeled (ie, different initial start ages Figure 2A shows the cost-effectiveness plane. MPs were least costly
chosen) within a sensitivity analysis. Convergence was checked by (692V), retaining teeth for 26.7 years. GFs were ranked next according
inspecting sampling distributions. to their costs (745V), retaining teeth for 27.6 years. MCs were mini-
Costs and effectiveness for different strategies were assessed, and mally more effective (27.6 years after rounding) but also more costly
cost-effectiveness planes were used to depict cost-effectiveness. Strategies than GFs (774V). CFs were less effective and more expensive than

Figure 2. Cost-effectiveness plane and cost-effectiveness acceptability. (A) Costs and effectiveness of different treatments were plotted. MPs were least costly.
GFs were more costly but also more effective, with ICER of 70V/year per tooth retention year. MCs were more effective but also more costly, with ICER of
670V. CFs were most costly and less effective than alternatives. (B) Cost-effectiveness acceptability curve indicates how with increasing willingness to pay, the
probability of cost-effectiveness for different treatments changes. GF is most likely to be cost-effective for payers willing to invest between 60V and 740V per
year; for those with higher willingness to pay, MC had the highest probability.

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TABLE 3. Strategy Ranking and ICERs, Compared with the Next Higher- one has to weigh the initial treatment costs against the risk of fatal and
Ranked Strategy non-fatal complications, which both affect the effectiveness and also the
Strategy Rank Costs (V) Effectiveness (y) ICER costs emanating from any treatments for mending complications. The
chosen model-based approach was suitable for evaluating the cost-
MP 1 692 26.7 — effectiveness of different post-retained crown restorations.
GF 2 745 27.6 60
MC 3 774 27.6 670 We found that long term, MC and GF show very similar effectiveness,
CF 4 825 26.7 –57 which is in line with clinical trial data (7). However, GF was less costly.
That was despite GF generating similar costs for the initial placement, with
Rankings were performed according to costs. A positive ICER indicates additional costs per gained
costs for the post material and the adhesive luting and core buildup
effectiveness; negative ICER indicates lost effectiveness per additional costs.
compensating any cost savings from avoiding laboratorial manufacturing.
alternatives (825V, 26.7 years); these were dominated. Rankings and Instead, the observed cost savings of GF compared with MC were mainly
ICERs are shown in Table 3. due to fewer non-fatal complications occurring, which reduced the costs
For payers unwilling to pay additional money for gained effective- of retreatments (such as recementation or renewal of the post-retained
ness, MP had >90% probability of being cost-effective (Fig. 2B). This crown). Moreover, we found that one driver of costs is endodontic
probability decreased markedly with increasing willingness to pay. retreatments (especially non-surgical retreatment) because the benefit
For payers willing to invest more than 60V per tooth retention year, in effectiveness is limited, whereas costs are substantial. That could be
GF had a probability of >40% of being cost-effective, exceeding 50% seen when assuming fiber posts to not receive such treatment because
for payers willing to invest 180V to 730V per tooth retention year. of difficulties in providing orthograde retreatment. In this case, GF was
Above this threshold, MC (which was most effective but also more costly nearly as effective but substantially less costly than MC. However, one
than GF) had a probability of >50% of being cost-effective. should note that the cost difference between non-surgical and surgical
retreatment might not apply to all settings and might well depend on
how exactly both treatments are performed. On the basis of our findings,
Sensitivity Analyses
decision makers willing to invest additional money can choose both GF
Sensitivity analyses were performed to explore parameter uncer- and MC. Because of the high additional long-term costs of MC and the
tainty and heterogeneity (Table 4). In younger patients, the ranking minimal gain in effectiveness as well as the poor esthetics of MC (which
remained stable, whereas overall, costs increased because of longer might be relevant in anterior teeth, not–as modeled–molars), decisions
time periods available for retreatments. In older patients, the ranking toward GF might well be justifiable.
was again stable, with reduced total costs. Assuming that non-surgical MP was the least costly option in all scenarios and might be consid-
(orthograde) endodontic retreatments would never be performed ered in case of strict cost containment, ie, in payers with no willingness
decreased the costs but also the effectiveness of all strategies, with to pay for gained effectiveness. It should be noted that these cost advan-
the ranking being unchanged compared with the base-case. Assuming tages were only minimal in case all teeth were replaced, because the
the opposite (all endodontic complications being first mended non- relatively higher risk of fatal complications and the subsequent costs
surgically) increased the costs and minimally also the effectiveness; for replacement nearly compensated initial savings. In such cases, GF
the ranking was unchanged. Assuming that adhesively placed fiber might be a highly acceptable option (because the additional costs are
post-retained restorations would not receive non-surgical retreatment minimal, whereas the gained effectiveness was substantial).
whereas conventionally cemented metal posts would altered the We found CF to not have acceptable cost-effectiveness because it
ranking, with GF now being the least costly option and MC being only was less effective than MC or GF and generally more expensive. More
minimally more effective. Assuming removed molars to not be replaced specifically, CF had the highest risk of non-fatal complications and
by using implants decreased the costs significantly (effectiveness was also high risks of fatal complications, coupled with higher costs than
not affected), with the ranking remaining unchanged. Setting the GF and MC except for one scenario shown in Table 4, namely ‘‘Revision
discounting rate to 0% or 5% decreased or increased the costs and only in metal post-retained crowns’’ where CF incurred lower costs than
effectiveness, respectively, but did not alter the ranking. MC but still higher costs than GF. On the basis of cost-effectiveness
considerations, CF cannot be recommended.
Discussion This study has a number of limitations. First, the applied model
Assessing long-term cost-effectiveness is complex, especially when greatly simplifies the clinical long-term flow of events, yet it allowed a
dealing with the consequences of an initial treatment decision, because range of relevant scenario analyses that confirmed the robustness of

TABLE 4. Cost-effectiveness of Different Strategies in the Base-case and Sensitivity Analyses


MC MP GF CF
Scenario c (V) e (y) c (V) e (y) c (V) e (y) c (V) e (y)
Base-case 774 27.6 692 26.7 745 27.6 825 26.7
Patient aged 40 y 856 36.0 769 34.7 809 36.0 909 34.7
Patient aged 60 y 689 18.8 609 18.4 661 18.8 711 18.4
No revision 722 27.3 645 26.6 693 27.3 768 26.6
All revision 817 27.6 730 26.8 778 27.6 868 26.8
Revision only in MPs 817 27.6 730 26.9 693 27.3 768 26.6
0% replaced 688 27.6 569 26.8 651 27.6 692 26.8
100% replaced 856 27.6 815 26.8 820 27.6 940 26.8
0% discounting 788 28.4 702 27.7 754 28.4 846 27.5
5% discounting 763 27.0 683 26.3 729 27.0 799 26.2
Costs (c) and effectiveness (e) are displayed. The least costly strategy is indicated in bold, and the most effective strategy is underlined. Sensitivity analyses evaluated how different patient ages, treatment decisions
for or against revision in case of endodontic failure, different replacement ratios for missing teeth, and different discounting rates affected the cost-effectiveness.

JOE — Volume 43, Number 5, May 2017 Cost-effectiveness of Different Endodontic Posts 713
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