Tugas 1 Ade Rahmawati - 18334032 Farmakologi (K) PPT Umpan Balik Negatif Hormon

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736\slmult0 \par\pard\ql\li1518\sb0\sl-736\slmult0 \par\pard\ql\li1518\sb0\sl-
736\slmult0 \par\pard\ql\li1518\sb191\sl-736\slmult0 \up0 \expndtw0\charscalex97
\ul0\nosupersub\cf1\f2\fs64 Umpan Balik Negatif Pembentukan Hormon \par\pard\ql
\li5685\sb0\sl-598\slmult0 \par\pard\ql\li5685\sb0\sl-598\slmult0
\par\pard\ql\li5685\sb22\sl-598\slmult0 \up0 \expndtw0\charscalex97
\ul0\nosupersub\cf2\f3\fs52 Disusun Oleh : \par\pard\ql \li4427\sb22\sl-598\slmult0
\up0 \expndtw0\charscalex97 Ade Rahmawati 18334032 \par\pard\ql \li6407\sb22\sl-
598\slmult0 \up0 \expndtw0\charscalex97 \ul0\nosupersub\cf3\f4\fs52 Dosen :
\par\pard\ql \li4266\sb42\sl-598\slmult0 \up0 \expndtw0\charscalex96
\ul0\nosupersub\cf2\f3\fs52 Dr. Refdanita, S.Si, M.Si, Apt
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483\slmult0 \up0 \expndtw0\charscalex106 \ul0\nosupersub\cf9\f10\fs42 PENGATURAN
OLEH
HORMON\par\pard\sect\sectd\sbknone\cols2\colno1\colw10582\colsr160\colno2\colw3518\
colsr160\ql \li6278\sb0\sl-368\slmult0 \par\pard\ql \li6278\sb0\sl-368\slmult0
\ul0\nosupersub\cf10\f11\fs32 HIPOTALAMUS\par\pard
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\ul0\nosupersub\cf13\f14\fs28 LIBERIN (FAKTOR PEMBEBAS)\par\pard\column \ql
\li10742\sb0\sl-276\slmult0 \par\pard\ql \li10742\sb0\sl-276\slmult0
\par\pard\ql \li10742\sb0\sl-276\slmult0 \par\pard\ql \li20\sb27\sl-276\slmult0
\up0 \expndtw0\charscalex101 \ul0\nosupersub\cf12\f13\fs24 ORGAN PENGATUR PUSAT
\par\pard\sect\sectd\sbknone \ql \li7084\sb50\sl-884\slmult0 \up0
\expndtw0\charscalex40 \ul0\nosupersub\cf11\f12\fs104
1\par\pard\sect\sectd\sbknone\cols2\colno1\colw8119\colsr40\colno2\colw6101\colsr16
0\ql \li5433\sb285\sl-333\slmult0\tx6348 \up0 \expndtw0\charscalex97
\ul0\nosupersub\cf13\f14\fs28 \u8226? \tab \up0 \expndtw0\charscalex108
\ul0\nosupersub\cf10\f11\fs32 HIPOFISIS\par\pard\column
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\par\pard\sect\sectd\sbknone \ql \li5452\sb309\sl-322\slmult0 \up0 \expndtw-
1\charscalex100 \ul0\nosupersub\cf13\f14\fs28 HORMON GLANDO TROPIK \par\pard\ql
\li7084\sb0\sl-1037\slmult0 \up0 \expndtw0\charscalex40
\ul0\nosupersub\cf15\f16\fs122\ul 1 \par\pard\ql \li5620\sb0\sl-288\slmult0 \up0
\expndtw0\charscalex98 \ul0\nosupersub\cf10\f11\fs32 KELENJAR PERIFER
\ul0\nosupersub\cf16\f17\fs84 1 \par\pard\li5318\sb39\sl-322\slmult0\fi0\tx10444
\up0 \expndtw-1\charscalex100 \ul0\nosupersub\cf13\f14\fs28 HORMON EFEKTORIK\tab
\up0 \expndtw-1\charscalex100 PENYEBAB EFEK\par\pard\ql \li7084\sb169\sl-
787\slmult0 \up0 \expndtw0\charscalex40 \ul0\nosupersub\cf17\f18\fs80 1
\par\pard\qj\pvpg\phpg\posx6364\posy10720\absw1679
\expndtw0\charscalex290\ul0\nosupersub\cf18\f19\fs8 'I A
r1TRI,"'ARI\par\pard\sect\sectd\fs24\landscape\paperw14400\paperh10800\pard\sb0\sl-
240{\bkmkstart Pg3}{\bkmkend Pg3}\par\pard\ql \li6126\sb691\sl-736\slmult0 \up0
\expndtw0\charscalex97 \ul0\nosupersub\cf1\f2\fs64 Hormon \par\pard\ql
\li864\sb0\sl-613\slmult0 \par\pard\ql\li864\ri720\sb313\sl-613\slmult0 \up0
\expndtw0\charscalex97 . \ul0\nosupersub\cf5\f6\fs56 Hormon adalah zat kimia yang
disekresi dalam cairan \line \up0 \expndtw0\charscalex97 tubuh oleh suatu sel atau
kelompok sel dan \line \up0 \expndtw0\charscalex97 menimbulkan efek pengaturan
fisiologis pada sel - sel \line \up0 \expndtw0\charscalex98 lain \par\pard\ql
\ul0\nosupersub\cf6\f7\fs56 Pengaruh Hormon Bagi Tubuh \par\pard\ql
\li864\ri651\sb133\sl-600\slmult0 \up0 \expndtw0\charscalex97
\ul0\nosupersub\cf5\f6\fs56 Hormon dalam jumlah yang sangat kecil bisa memicu \line
\up0 \expndtw0\charscalex98 respon tubuh yang sangat luas, hormon terikat kepada
\ul0\nosupersub\cf6\f7\fs56 reseptor di permukaan sel atau di dalam sel. Ikatan
\par\pard\ql \li864\ri1924\sb22\sl-600\slmult0 \up0 \expndtw0\charscalex96
\ul0\nosupersub\cf5\f6\fs56 antara hormon dan reseptor akan mempercepat, \line \up0
\expndtw0\charscalex97 memperlambat atau merubah fungsi sel
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\pard\sb0\sl-240{\bkmkstart Pg4}{\bkmkend Pg4}\par\pard\ql \li3882\sb691\sl-
736\slmult0 \up0 \expndtw0\charscalex96 \ul0\nosupersub\cf1\f2\fs64 Pengaturan Oleh
Hormon \par\pard\ql \li994\sb0\sl-598\slmult0 \par\pard\ql\li994\sb240\sl-
598\slmult0 \up0 \expndtw0\charscalex97 \ul0\nosupersub\cf2\f3\fs52 . Hipotalamus
adalah organ pengatur pusat \par\pard\ql \li994\ri714\sb103\sl-500\slmult0\fi117
\up0 \expndtw0\charscalex97 . Akibat pembebasan liberin ( faktor pembebas )
sehingga \line \up0 \expndtw0\charscalex97 dalam hipofisis terjadi pembebasan/
pembentukan \line \up0 \expndtw0\charscalex98 hormon kedua yaitu hormon
glandotropik/hormon tropik \par\pard\ql \li994\sb40\sl-598\slmult0 \up0
\expndtw0\charscalex97 . Hormon glandotropik mempengaruhi kelenjar endokrin
\par\pard\ql \li994\ri436\sb0\sl-500\slmult0 \up0 \expndtw0\charscalex97 perifer
dan merangsang produksi dan pembebasan hormon \line \up0 \expndtw0\charscalex96
ketiga dari kelenjar perifer yang terdistribusi bersama \line \up0
\expndtw0\charscalex96 aliran darah ke seluruh organ dan menimbulkan reaksi yang
\line \up0 \expndtw0\charscalex97 sesungguhnya dalam sel yang memiliki reseptor
hormon \line \up0 \expndtw0\charscalex98 tersebut \par\pard\ql \li994\sb23\sl-
598\slmult0 \up0 \expndtw0\charscalex97 \ul0\nosupersub\cf3\f4\fs52 . Hormon ini
bekerja secara langsung pada organ yang \par\pard\ql \li994\sb1\sl-479\slmult0 \up0
\expndtw0\charscalex96 \ul0\nosupersub\cf2\f3\fs52 dituju, disebut hormon efektor
(penyebab efek)
\par\pard\sect\sectd\fs24\landscape\paperw14400\paperh10800\pard\sb0\sl-
\expndtw0\charscalex97 \ul0\nosupersub\cf1\f2\fs64 Umpan Balik Aktivitas Hormon
\par\pard\ql \li3952\sb0\sl-644\slmult0 \par\pard\ql\li3952\sb416\sl-644\slmult0
\up0 \expndtw0\charscalex97 \ul0\nosupersub\cf6\f7\fs56 Jumlah hormon dalam
darah \par\pard\ql \li3940\sb0\sl-644\slmult0 \par\pard\ql\li3940\sb332\sl-
644\slmult0 \up0 \expndtw0\charscalex96 \ul0\nosupersub\cf5\f6\fs56 Mekanisme
homeostatis \par\pard\li4872\sb0\sl-644\slmult0\par\pard\li4872\sb332\sl-
644\slmult0\fi0\tx8894 \up0 \expndtw0\charscalex96 Kelenjar\tab \up0
\expndtw0\charscalex96 Sel\par\pard\li4872\sb163\sl-644\slmult0\fi0\tx8789 \up0
\expndtw0\charscalex96 Hormon\tab \up0 \expndtw0\charscalex96
Target\par\pard\sect\sectd\fs24\landscape\paperw14400\paperh10800\pard\sb0\sl-
\expndtw0\charscalex97 \ul0\nosupersub\cf1\f2\fs64 Sistem Umpan Balik
\par\pard\ql \li864\sb0\sl-673\slmult0 \par\pard\ql\li864\ri510\sb204\sl-
673\slmult0 \up0 \expndtw0\charscalex97 \ul0\nosupersub\cf5\f6\fs56 . Dalam sistem
endokrin, umpan balik mengacu kepada \line \up0 \expndtw0\charscalex96 efek yang
ditimbulkan oleh pengaktifan target organ \line \up0 \expndtw0\charscalex97 oleh
hormon terhadap pelepasan hormon tersebut \line \up0 \expndtw0\charscalex98 lebih
lanjut \par\pard\ql \li864\sb151\sl-644\slmult0 \up0 \expndtw0\charscalex97
\ul0\nosupersub\cf6\f7\fs56 . Setiap hormon dirangsang pelepasannya oleh suatu
\ul0\nosupersub\cf5\f6\fs56 sinyal khusus. Setelah dilepaskan, hormon
\par\pard\ql \li864\sb36\sl-644\slmult0 \up0 \expndtw0\charscalex96 mempengaruhi
organ sasarannya dan menimbulkan \par\pard\ql \li864\sb16\sl-644\slmult0 \up0
\expndtw0\charscalex97 \ul0\nosupersub\cf6\f7\fs56 respons yang mengurangi atau
menambah pelepasan \par\pard\ql \li864\sb36\sl-644\slmult0 \up0
\expndtw0\charscalex97 \ul0\nosupersub\cf5\f6\fs56 hormon tersebut lebih lanjut
\par\pard\sect\sectd\fs24\landscape\paperw14400\paperh10800\pard\sb0\sl-
\expndtw0\charscalex97 \ul0\nosupersub\cf1\f2\fs64 Umpan Balik Negatif \par\pard\ql
\li864\sb0\sl-644\slmult0 \par\pard\ql\li864\sb196\sl-644\slmult0\tx1403 \up0
\expndtw0\charscalex97 \ul0\nosupersub\cf7\f8\fs56 \u8226? \tab \up0
\expndtw0\charscalex97 \ul0\nosupersub\cf5\f6\fs56 1. Setiap kelenjar endokrin
secara alamiah \par\pard\ql \li1403\sb1\sl-590\slmult0 \up0
\expndtw0\charscalex96 \ul0\nosupersub\cf6\f7\fs56 mempunyai tendensi untuk
oversekresi hormonnya \par\pard\ql \li864\ri557\sb142\sl-600\slmult0\tx1403 \up0
\expndtw0\charscalex97 \ul0\nosupersub\cf7\f8\fs56 \u8226? \tab \up0
\expndtw0\charscalex97 \ul0\nosupersub\cf5\f6\fs56 2. Karena tendensi ini, maka
hormon yang dihasilkan \line \up0 \expndtw0\charscalex98 akan sangat banyak
\par\pard\li864\sb121\sl-644\slmult0\fi0\tx1403 \up0 \expndtw0\charscalex96
\ul0\nosupersub\cf8\f9\fs56 \u8226?\tab \up0 \expndtw0\charscalex96
\ul0\nosupersub\cf6\f7\fs56 3. Organ target akan menjalankan fungsiya
akibat\par\pard\li864\sb1\sl-596\slmult0\fi539 \up0 \expndtw0\charscalex96
\ul0\nosupersub\cf5\f6\fs56 pengaruh hormon\par\pard\ql \li864\sb103\sl-
644\slmult0\tx1403 \up0 \expndtw0\charscalex97 \ul0\nosupersub\cf7\f8\fs56
\u8226? \tab \up0 \expndtw0\charscalex96 \ul0\nosupersub\cf5\f6\fs56 4. Ketika
fungsi pada organ target sudah terlalu \par\pard\ql \li1403\sb1\sl-590\slmult0 \up0
\expndtw0\charscalex96 \ul0\nosupersub\cf6\f7\fs56 banyak, maka ada faktor tertentu
yang memberikan \par\pard\ql \li1403\ri1608\sb2\sl-600\slmult0 \up0
\expndtw0\charscalex96 \ul0\nosupersub\cf5\f6\fs56 efek negatif ke kelenjar agar
mengurangi jumlah \line \up0 \expndtw0\charscalex97 hormon yang disekresi
\par\pard\sect\sectd\fs24\landscape\paperw14400\paperh10800{\bkmkstart Pg8}
{\bkmkend Pg8}\par\pard\ql \li6849\sb1601\sl-2346\slmult0 \up0
\expndtw0\charscalex80 \ul0\nosupersub\cf19\f20\fs204 ienio 6 \par\pard\ql
\ul0\nosupersub\cf20\f21\fs204 4,rwo'vl1 \par\pard\sect\sectd\fs24}

Tugas 1 Ade Rahmawati - 18334032 Farmakologi (K) PPT Umpan Balik Negatif Hormon

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