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INT J LANG COMMUN DISORD, MAY–JUNE 2018,

VOL. 53, NO. 3, 446–467

Review
A systematic review and classification of interventions for speech-sound
disorder in preschool children
Yvonne Wren†‡, Sam Harding†, Juliet Goldbart§ and Sue Roulstone†¶
†Bristol Speech and Language Therapy Research Unit, North Bristol NHS Trust, Bristol, UK
‡Faculty of Health Sciences, University of Bristol, UK
§Faculty of Health, Psychology and Social Care, Manchester Metropolitan University, UK
¶Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK
(Received May 2017; accepted December 2017)

Abstract
Background: Multiple interventions have been developed to address speech sound disorder (SSD) in children.
Many of these have been evaluated but the evidence for these has not been considered within a model which
categorizes types of intervention. The opportunity to carry out a systematic review of interventions for SSD arose
as part of a larger scale study of interventions for primary speech and language impairment in preschool children.
Aims: To review systematically the evidence for interventions for SSD in preschool children and to categorize them
within a classification of interventions for SSD.
Methods & Procedures: Relevant search terms were used to identify intervention studies published up to 2012, with
the following inclusion criteria: participants were aged between 2 years and 5 years, 11 months; they exhibited
speech, language and communication needs; and a primary outcome measure of speech was used. Studies that
met inclusion criteria were quality appraised using the single case experimental design (SCED) or PEDro-P,
depending on their methodology. Those judged to be high quality were classified according to the primary focus
of intervention.
Outcomes & Results: The final review included 26 studies. Case series was the most common research design.
Categorization to the classification system for interventions showed that cognitive–linguistic and production
approaches to intervention were the most frequently reported. The highest graded evidence was for three studies
within the auditory–perceptual and integrated categories.
Conclusions & Implications: The evidence for intervention for preschool children with SSD is focused on seven out
of 11 subcategories of interventions. Although all the studies included in the review were good quality as defined
by quality appraisal checklists, they mostly represented lower-graded evidence. Higher-graded studies are needed
to understand clearly the strength of evidence for different interventions.

Keywords: speech-sound disorder, systematic review, Child Talk, intervention.

What this paper adds


What is already known on the subject
A wide range of interventions are available for speech and language therapists to use when working with children
with SSD. While some intervention approaches have robust evidence to support them, others do not have evidence
or have more limited evidence.

What this paper adds to existing knowledge


This study systematically reviewed the evidence for those interventions that have been tested with children under
6 years of age. A model for classification of intervention studies in SSD is proposed and the evidence to support
interventions within the model provided.

Address correspondence to: Yvonne Wren, Bristol Speech and Language Therapy Research Unit, Pines and Steps, Southmead Hospital,
Westbury-on-Trym, Bristol BS10 5NB, UK; e-mail: Yvonne.wren@bristol.ac.uk
International Journal of Language & Communication Disorders
ISSN 1368-2822 print/ISSN 1460-6984 online  C 2018 Royal College of Speech and Language Therapists

DOI: 10.1111/1460-6984.12371
Systematic review of speech interventions 447

What are the potential or actual clinical implications of this work?


Speech and language therapists will be able to identify at a glance which interventions that have been tested
with children under age 6 have evidence to support them. Evidence is varied in strength and intervention
studies using more robust research designs are needed to test fully the interventions described in the current
literature.

Introduction these interventions had been subject to meta-analysis or


included in a randomized controlled trial, the major-
Speech-sound disorder (SSD) is a high-prevalence con-
ity had been subject to less rigorous investigations such
dition in preschool children (Broomfield and Dodd
as quasi-experimental or non-experimental case studies.
2004, Eadie et al. 2015, McLeod and Harrison 2009,
Baker and McLeod concluded that more rigorous exper-
Shriberg et al. 1999). In response to this, a number of in-
imental design is required to enable the relative benefits
terventions have been developed that vary in the method
of any intervention or approach to be determined.
used to achieve change in a child’s speech (Baker and
The interpretation of Baker and McLeod’s review
McLeod 2011).
in a clinical context is challenging. Authors of differing
To date, a number of systematic literature reviews
theories and approaches often provide clear guidance
have examined the effectiveness of these interventions
regarding the most appropriate intervention to use with
for children with SSD across the age range. Some of
children with differing presentations (e.g., Dodd and
the reviews were part of a larger and more comprehen-
Bradford 2000). However, without comparisons of the
sive review of speech and language therapy interventions
efficacy or effectiveness of one approach over another
for children with speech and language delay or disorder
for the full range of approaches available, clinicians are
(Law et al. 2003, 2012, 2015), while others have fo-
left without clear evidence of the best approach to use.
cused specifically on speech (Baker and McLeod 2011,
This challenge is well illustrated in the 2006 special issue
Murray et al. 2014) or on a specific type of interven-
of Advances in Speech–Language Pathology on ‘Jarrod’, a
tion (Lee et al. 2009, Lee and Gibbon 2015, McCauley
7-year-old boy with SSD (McLeod, 2006). This sympo-
et al. 2009, Morgan and Vogel 2008). While those fo-
sium published papers by different authors, who were
cusing on specific interventions revealed a paucity of
invited to advocate and describe their own approach to
studies with sufficient strength to provide categorical
intervention for this child. The different interventions
support for the approaches (specifically, electropalatog-
were all well argued and justified at a theoretical level but
raphy, non-speech oral motor exercises and interven-
not compared with each other, and there was no con-
tions for childhood apraxia of speech), the results of
clusion regarding which approach might be the most
the more extensive reviews were encouraging. Law et al.
effective or efficient.
(2003) included only randomized controlled trials in
The recognition that different approaches to inter-
their review and found convincing support for inter-
vention may be needed for children with different pre-
ventions where the outcome was the child’s ‘expressive
sentations of SSD has led to a widespread call in the
phonology’. Similarly, the review by Law et al. (2012)
literature for more detailed assessment and analysis of
found that of 57 interventions included in the review,
SSD (McLeod and Baker 2004, Skahan et al. 2007,
approximately one-third (38%) targeted speech. Evi-
Stackhouse and Wells 1997). In the absence of this, clin-
dence for most of these interventions was at a moderate
icians tend to favour the use of just two or three named
level (68%), i.e., tested in either a randomized controlled
approaches, often combined into one eclectic package,
trial or several quasi-experimental studies, whilst for oth-
presumably with the expectation that one of the ele-
ers the evidence was at an indicative level, i.e., they have
ments within the package will target the child’s specific
good face validity and are widely used by clinicians, but
needs (Joffe and Pring 2008, McLeod and Baker 2004,
have limited research evidence that can be generalized
Roulstone et al. 2012). The approaches named by speech
to the population concerned.
and language therapists as most frequently used often
Baker and McLeod (2011) included a wider range of
lack detail and are ambiguous in terms of how exactly
study designs in their narrative review of evidence-based
they are delivered or interpreted. Terms such as ‘auditory
practice for children with SSD. Samples in these stud-
discrimination’, ‘meaningful minimal contrast’, ‘phono-
ies included participants with concomitant difficulties
logical awareness’ (Joffe and Pring 2008), ‘traditional
such as hearing loss, cleft lip and/or palate, or stut-
articulation therapy’ and ‘minimal pairs’ (McLeod and
tering and spanned an age range of 1;11–10;5. They
Baker 2004) and ‘minimal pairs’, ‘auditory discrimina-
identified a total of 154 studies which described seven
tion’ and ‘sequencing sounds’ (Roulstone et al. 2015)
different methods for target selection and 46 different
are cited as commonly used interventions. Therefore,
approaches to intervention. While a small number of
448 Yvonne Wren et al.
it is not clear how far the approaches used frequently in this model but the area where change is expected to
by clinicians map onto the approaches described in the occur and which indeed is being targeted in the inter-
intervention literature. vention has been identified and categorized accordingly
There is a need to appraise systematically the evi- (figure 1).
dence for intervention in SSD and then map that onto The model labels five categories of intervention: en-
the approaches described by clinicians. In this way, vironmental, auditory–perceptual, cognitive–linguistic,
speech and language therapists with a busy and var- production and integrated. The environmental
ied caseload would be more easily able to identify the approach is distinct from the others in that it en-
strength of evidence for interventions that fit with the compasses intervention approaches that make use of
approach they determine is needed for an individual everyday interactions, rather than specific directed ac-
child. tivities, to promote change in a child’s speech-sound
system. This would include procedures sometimes de-
A model for the classification of interventions scribed as ‘naturalistic intervention’ as well as the mod-
elling and recasting of a child’s spontaneous productions
for SSD
(Camarata 2010). Auditory perceptual interventions
Existing classifications of SSD have focused on the target the child’s perceptual skills as a means to induce
child’s aetiology (Shriberg et al. 2010), their surface- change in speech output and include activities that aim
level speech presentation (Dodd 2005) or their speech- to increase exposure to the sounds being targeted, as in
processing skills (Stackhouse and Wells 1997). A useful focused auditory stimulation, and discrimination tasks
summary of these approaches is provided by Waring and designed to increase phoneme perception skills (Hodson
Knight (2011). While the Dodd classification provides and Paden 1991, Rvachew and Brosseau-Lapré 2010).
guidance regarding which interventions map onto each Cognitive–linguistic interventions engage the child in
identified subtype, this only covers a small number of the higher-level processing in which the child’s awareness of
range of interventions available, as identified by Baker their speech is consciously addressed and used to pro-
and McLeod (2011). An alternative approach is to clas- mote change, through either confronting a child with
sify interventions and attempt to map this onto the kinds their reduced set of contrasts or increasing awareness of
of difficulties that children with SSD might experience. sounds in speech generally. Interventions focusing on
This approach has been adopted in descriptions of inter- production aim to effect change through performance
vention approaches by Bernthal et al. (2012), Rvachew of oro-motor tasks, guidance on phonetic placement or
and Brosseau-Lapré (2012) and Stackhouse and Wells manner, imitation and drills. Integrated interventions
(1997). Typically, interventions have been grouped as are simply those that combine two or more of the other
regards the level of processing they are primarily target- four through profiling of the child’s specific needs as
ing: ‘input’, where the child is required to respond to in the psycholinguistic approach (Stackhouse and Wells
some auditory stimuli to effect change in their speech; 1997) or combining procedures into a programme of
‘storage’, where the child is asked to reflect on their multiple interventions consistent with a ‘Cycles’ ap-
stored representations of words as a means to challenge proach to intervention, for example (Hodson and Paden
existing inaccurate representations; or ‘output’, which 1991).
require the child to produce speech in response to imi- The model does not reflect decisions around
tation or some other stimuli. phoneme target selection, though undoubtedly the de-
An extension of this approach was expanded in work cisions regarding procedure and target are related for
carried out by Wren (2005) and was used as the basis for many interventions. Nor does it attempt to link to aeti-
the work carried out in the systematic review reported ology. However, the model makes explicit where change
in this paper. Using a bottom-up approach from the in- is expected to occur as a consequence of intervention.
tervention procedures available and identified as in use It is anticipated that this would provide a summary of
by clinicians (Roulstone and Wren 2001), the model is the current evidence which is more easily accessible to
organized by the area where change is expected to occur clinicians, and therefore addresses some of the concerns
in order to facilitate change in speech output. It is hy- raised by Lancaster et al. (2010) regarding the incom-
pothetical and proposes one way of organizing types of patibility of research and clinical work.
intervention procedures and has changed since the orig-
inal version described by Wren (2005). As such, it has
Aims
the capacity to change further and evolve as new inter-
vention procedures and new evidence become available. The aim of this study was to review systematically and
Nonetheless, it provides an initial framework that is in- critically appraise the strength of the evidence for inter-
clusive of the diverse range of intervention procedures ventions for SSD in preschool children and then cate-
available to clinicians. Specific approaches are not named gorize those interventions which fulfilled the selection
Systematic review of speech interventions 449

Figure 1. Model of intervention procedures for targeting speech-sound disorder (SSD). [Colour figure can be viewed at wileyonlinelibrary.com]

criteria within the model of classifications of interven- to the study methodologies, and built on the review un-
tions for SSD described above. Studies of interest would dertaken by Pickstone et al. (2009). The search strategy
include children with SSD aged between 2 and 6 years; described below outlines the larger review carried out for
use a range of study designs; and measure outcomes the Child Talk research programme and describes how
in speech. The intention was that this would provide the studies relevant to SSD were identified within this.
an overview of current evidence for intervention for The systematic review was registered with PROSPERO
SSD with preschool children in an easily accessible for- (registration number CRD42013006369), an interna-
mat which could be quickly be mapped onto individual tional register of prospective systematic reviews.
children’s needs.
This study was part of a larger review of interven-
tions for children with speech and language impairment Search strategy
in preschool children with no concomitant difficulties The search strategy employed three key elements:
(Roulstone et al. 2015) within the ‘Child Talk’ research (1) the development of a comprehensive and relevant
programme, a series of research studies investigating the list of search terms to ensure that all potentially valid
evidence base for speech and language therapy interven- studies in relation to interventions for speech and lan-
tion for preschool children. guage impairment without concomitant difficulties were
returned; (2) the exploration of a suitably broad range
of databases to capture as many potentially valid stud-
Method
ies as possible, including published, unpublished and
The systematic review was guided by the principles conference proceedings; and (3) the identification of
outlined in the Cochrane Collaboration methodology clear inclusion criteria against which to filter potentially
(Higgins and Green 2011), as far as they could be applied valid studies and provide the dataset for analysis. The
450 Yvonne Wren et al.
authors and co-applicants of the Child Talk programme Search procedure
of research (Roulstone et al. 2015) identified a set of
A combination of ‘free text’ terms with Boolean opera-
search terms based on their previous work in the field
tors and truncations was used. Eighteen separate searches
(Blackwell et al. 2014, Hambly et al. 2013, Marshall
were conducted in electronic databases (see appendix B)
et al. 2011, Pickstone et al. 2009, Wren et al. 2013).
to identify appropriate studies in papers published from
Further potential search terms were identified from
the earliest entries of any of the databases until January
key papers. This expertise was augmented by consul-
2012. Papers were initially reviewed by title and then by
tation with information specialists. Through an itera-
abstract.
tive process of identification and discussion, a list of 90
search terms was determined to provide the most ap-
propriate set to capture potentially valid studies (see Reliability
appendix A). The same process was used to select
appropriate databases to ensure maximum inclusion Two of the authors independently reviewed the titles of
of published data, unpublished data and conference 10% of the papers identified from the initial search of
proceedings. the databases to screen for relevance, removing any stud-
In line with Booth and Fry-Smith (2003), the ies that did not fit the exclusion and inclusion criteria.
PICO model (population, intervention, comparison, There was 100% consensus and the remaining 33,000
outcome) guided the development of the inclusion crite- references were shared between these two authors and
ria. All research design methodologies were considered papers were excluded at the title level. This process lead
and therefore the ‘comparison’ element of the PICO to the retention of 4574 papers. The abstract review
model was not used to determine eligibility, but recorded was undertaken by four members of the research team,
during data extraction. For inclusion in the larger with two people for each manuscript (one speech and
Child Talk review, studies had to meet the following language therapist and one psychologist). Where dis-
requirements: agreements occurred, discussion took place within the
team until consensus was reached. Those papers retained
r Population: at least 80% of the sample was re- at this stage were then reviewed in their entirety in light
quired to be within the age range 2;00–5;11 at the of the inclusion and exclusion criteria.
start of the intervention or at recruitment; chil- The retained papers were further reduced to those
dren would be diagnosed or considered ‘at risk’ that had interventions which related to SSD. Studies
of speech and language impairment without con- were included at this stage if the intervention described
comitant difficulties. in the research was consistent with the definition: ‘Work
r Intervention: an empirical evaluation of an in- that increases the accuracy of speech production or ar-
tervention, including randomized controlled tri- ticulation, often focusing on specific sound(s).’ Those
als, experimental and quasi-experimental stud- studies that focused on phonological awareness skills
ies and case studies, which included multiple only and did not relate to speech output were excluded.
baseline or other systematic manipulation of the The remaining papers were then subjected to a quality
intervention. appraisal.
r Outcomes: at least one of the primary out-
come measures of included studies would address Quality appraisal
speech, language, communication or interaction;
at a later stage, those studies that included primary The quality appraisal tools used in this review were se-
outcome measures of speech were included in this lected to be relevant to the research designs used in the
topic specific review (see below). included studies. Two tools were used for this purpose:
(1) the Physiotherapy Evidence Database quality assess-
Studies were excluded if: ment tool (PEDro-P; Perdices and Tate 2009) had a
score range of 0–9 and was used to appraise the method-
ological quality of randomized and non-randomized
r they related to children whose speech or language controlled trials; and (2) single-case experimental de-
appeared to be developing typically with no evi- sign (SCED) had a score range of 0–10 and was used for
dence to suggest that their language was ‘at risk’; single case studies (Tate et al. 2008). All appraisers un-
r they related to children whose speech or language dertook and passed training on PEDro-P and SCED.1
delays were associated with other developmental Each paper was reviewed by at least two researchers, and
or pervasive conditions such as learning difficul- if disagreement had occurred, it was planned to discuss
ties, autism, cleft palate and cerebral palsy; and/or and reach consensus. This process was not required as
r the only outcomes were social or behavioural. agreement on the quality assessment was 100%. For
Systematic review of speech interventions 451
Table 1. Process of categorization of procedures in intervention for speech-sound disorder (SSD)

Auditory Cognitive
Environmental perceptual linguistic Production Combined

Description Procedures Procedures that target Procedures that require the Procedures that aim to Procedures that
incorporated listening and perceptual child to reflect on their effect change through combine two or more
into everyday skills speech and/or increase instruction on of the other four
interactions their awareness of speech production and categories into a
generally production practice tested intervention
Examples Modelling, Auditory discrimination, Contrast therapy, Drills, guidance on Cycles approach,
recasting focused auditory metalinguistic tasks phonetic placement or psycholinguistic
stimulation, phoneme manner, traditional approach
perception tasks articulation

both tools, a higher score was associated with a greater Subsequently, effect sizes for speech outcomes were
quality of the methodology applied and reported within calculated where data were available and appropriate.
the study. In line with previous reviews (Camarinos and This was undertaken using the Campbell Collabora-
Marinko 2009, Maher et al. 2003), a score of 6 or over tion effect size calculator.2 Studies using a within-subject
was used to identify studies of acceptable quality which pre-post-methodology providing sufficient information
would be retained in the review. These studies were then were assessed using a second online calculation tool3 and
mapped onto the classification of intervention proce- single-subject experimental designs were assessed using
dures model described above. improvement rate difference (IRD; Parker et al. 2011).

Data extraction and synthesis Results


The process of synthesis consisted of two stages. The first Figure 2 shows the Preferred Reporting Items for
stage extracted the characteristics of the studies relating Systematic Reviews and Meta-Analyses (PRISMA)4
to country, culture and language(s) of the researchers flowchart and summary of papers retrieved at each stage
and participants and to study designs categorized us- of the review. Of the 147 studies matching the inclusion
ing the National Health and Medical Research Coun- criteria for the Child Talk project as a whole, 55 could be
cil (NHMRC) levels of evidence guidelines (NHMRC mapped onto the speech theme. Twenty-five of these pa-
2007). A wide range of study designs was included in pers, reporting on 26 studies, demonstrated a sufficient
the review. This was to acknowledge that those with a level of quality (i.e., obtained of 6 or more) when as-
lower level of evidence could be developed into trials sessed using the PEDro-P or SCED scale. Of the 30 that
using higher-graded designs in future. did not attain a score of 6 or more on these measures,
The second stage extracted information on location 11 were reviewed using PEDro-P and 19 with SCED.
and agent of intervention, assessment and outcome mea- The mean average scores on these excluded studies were
sures used, number of treatment sessions, and a descrip- 4 and 3 respectively (medians of 4 and 3 respectively).
tion of the intervention provided. The description of the The most frequent deficits in the randomized and non-
intervention was used to map the study onto the model randomized controlled studies were lack of concealment
of intervention procedures. Specifically, the information during group allocation and lack of blinding of the as-
provided in the paper that described the procedures (as sessor who measured at least one key outcome. In the
opposed to targets or the underlying theory) carried out single-case experimental studies, the top three deficits in
to effect change in the child’s speech sounds was consid- reporting were: lack of raw data being reported; assessors
ered to identify the best fit with the categories within the not being independent of treatment/intervention; and
model described in the introduction. Where more than lack of replication either across subjects, therapists or
one type of procedure was included in the intervention setting.
protocol but only one category was under investigation,
the study would be classified under the category that was
Categorization of studies and reported outcomes
the best fit for the element of the intervention being in-
vestigated. Where a combination of types of procedure Of the 26 studies retained for inclusion, 18 were un-
had been implemented, these were noted and the study dertaken in the United States, four in Canada, three in
assigned to the ‘integrated’ category. Table 1 provides a Australia and one in the UK. Fifteen of the studies used
summary of the criteria used to categorize intervention a case series design and three were case studies. A further
procedures described in each paper. three studies used a randomized controlled trial design
452 Yvonne Wren et al.

Figure 2. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow chart. [Colour figure can be viewed at
wileyonlinelibrary.com]

and a further four used a between-groups design. The each of the studies in the review and provides summary
26 studies were categorized according to the procedure information on each obtained from the data extraction.
used in the intervention using the model in figure 3. Environmental approaches are represented by one
It was possible to calculate effect sizes in 10 of the stud- study. Yoder et al. (2005) was categorized here due to
ies and to provide a range of the improvement rate the intervention using recasting and modelling within
difference in single cases for three more. Table 2 details clinic contexts. This study found no main effect of the
Systematic review of speech interventions 453

Approaches to the procedures involved in intervenon for speech sound

1
Environmental Auditory Perceptual Cognive-Linguisc Producon Integrated Approaches

2
Combined
Phoneme Focused Oro-motor Guidance on Imitaon & Drill approaches Unspecified
Meaningful Complexity Meta-
Percepon Auditory Speech Phonec
Minimal approaches linguisc
Smulaon exercise Placement/
Contrast Includes
Manner
(phonological
awareness) Glogowska et al.2000
Yoder et al. 2005 Baker and McLeod 2004 Forrest and Elbert 2001
Rvachew 1994 Dodd and Iacono 1989 Forrest et al. 2000 Almost and Rosenbaum 1998
Rvachew et al. 2004 Robb et al. 1999 Gierut 1989 Gierut 1996 Hart and Gonzalez 2010
Wolfe et al. 2003 Gierut 1990 Gierut and Champion 2000 McIntosh and Dodd 2008
Gierut and Champion 1999 Gierut and Champion 2001 Saben and Ingham 1991
Gierut et al. 1996 (both studies) Gierut and Morrisee 1996
Rvachew and Nowak 2001 Winner and Elbert 1988

1 = Includes modelling and recasng and other approaches which are embedded in everyday interacons
2 = Imitaon /spontaneous producon of sounds in a progressively more complex context - syllables, words or non-words

Figure 3. Evidence for intervention procedures for preschool children with speech-sound disorder (SSD). [Colour figure can be viewed at
wileyonlinelibrary.com]

broad target recast intervention but did report a posi- No studies were included in the review under the cate-
tive long-term impact on intelligibility for children with gory of metalinguistic approaches.
low pretreatment speech accuracy in comparison with Studies within the review that came under the cat-
standard care. egory of production were identified within the subcate-
Within the category of auditory perceptual ap- gories of ‘oro-motor speech exercises’, ‘guidance on pho-
proaches, the subcategory of phoneme perception ap- netic placement/manner’ and ‘imitations and drill’. No
proaches was used in three studies (Rvachew 1994, studies were categorized under ‘oro-motor speech ex-
Rvachew et al. 2004, Wolfe et al. 2003). The children ercises’ or ‘guidance on phonetic placement/manner’.
in Rvachew (1994) were randomly allocated to three The seven studies within the ‘imitations and drill’ sub-
groups and these children were given listening tasks fo- category all worked on increasing the complexity of ar-
cused on treatment of misarticulated versions of target ticulation in graded steps such as breaking words into
words. Rvachew et al. (2004) used training in phone- constituent sounds and subsequently recombining to
mic perception, letter recognition, letter–sound associ- form the word (Forrest and Elbert 2001, Forrest et al.
ation and onset-rime matching. Both studies found a 2000, Gierut 1996, Gierut and Champion 1999, 2001,
positive effect of the intervention. In contrast, Wolfe Gierut and Morrisette 1996, Winner and Elbert 1988).
et al. (2003) compared sound identification training Five of these studies showed an improvement in the in-
plus production training with production-only train- tervention group (Forrest and Elbert 2001, Forrest et al.
ing and found no difference between the two groups 2000, Gierut and Champion 2000, 2001, Gierut and
except for sounds which were poorly identified prior Morrisette 1996), while in two studies there was no sta-
to intervention. None of the studies in the review tistical impact of the intervention on the child’s speech
was classified under the focused auditory stimulation output (Gierut 1996, Winner and Elbert 1988). It is
subcategory. important to note, however, that the purpose of the in-
Cognitive–linguistic approaches were the most com- tervention Winner and Elbert (1988) was to investigate
monly reported interventions within the studies in the the impact of administering repeated probes during in-
review. These studies focused on three subcategories of tervention with the intention that a desired outcome
intervention: ‘meaningful minimal contrast’ approaches, would be no change in performance on the probe mea-
‘complexity’ approaches and ‘metalinguistic approaches’. sure, indicating that this approach can continue to be
Three studies focused on meaningful minimal contrast used in future trials of intervention for SSD.
(Baker and McLeod 2004, Dodd and Iacono 1989, ‘Integrated’ approaches to intervention were repre-
Robb et al. 1999) and a further six studies (from five sented by studies within the subcategories of ‘combined’
papers) form the evidence base for (Gierut 1989, 1990, approaches and ‘unspecified’. Combined approaches
Gierut and Champion 1999, Gierut et al. 1996) and were adopted in four studies included in the review
against (Rvachew and Nowak 2001) complexity ap- (Almost and Rosenbaum 1998, Hart and Gonzalez
proaches. These studies have small samples but suggest 2010, McIntosh and Dodd 2008, Saben and Ingham
a positive impact of the interventions on the children, 1991). They used a combination of activities and strate-
with one exception where change to the target of inter- gies as interventions, described as being targeted at the
vention was not observed (Gierut and Champion 1999). individual child’s needs or as routine one-to-one therapy.
454
Table 2. Summary of studies from the systematic review

Number of child
participants (number No. of therapy Effect size Cohen d
Reference and of children in each Age range Study design (type of sessions/agent of Length of each Frequency of Duration of type of speech Analysis used to PEDro-P/SCED unless otherwise
country of origin group, if applicable) (months) evidencea ) delivery session (min) sessions intervention sampled measure change score specified

Environmental
Yoder et al. 52 (26, 26) Group 1: Randomized (type II) Group 1: control 0; 30 min Three times per 6 months Spontaneous Percentage intelligible PEDro-P 7 49 (taken directly
(2005), USA average 44.3 Group 2 week speech utterance from the paper)
Group 2: (treatment PVCb
average 43.2 group) 72/SLP PCCb

Auditory perceptual: phoneme perception


Rvachew (1994), 27 (10, 9, 8) Group 1: Randomized (type II) 6/SLP 45 min Weekly 6–11 weeks Word Percentage correct PEDro-P 6 0.0092
Canada average 53.4 identification word identification
Group 2: Single word Number of single
average 53.6 naming words produced
Group 3: correctly
average 51.5

Rvachew et al. 34 (17, 17) Group 1: Randomized (type II) 16 (in addition to 15 min Weekly 4.73 months Conversation PCCb PEDro-P 6 0.8316
(2004), average 52.88 their regular
Canada Group 2: therapy)/SLP
average 50.29
Wolfe et al. 9 (4, 5) Group 1: Comparative Average 30 min Twice weekly One academic Probe list Accuracy of PEDro-P 6 –0.3634
(2003), USA 47–55 studies— 11/SLP quarter production
Group 2: randomized Sound identification
41–50 therapy approach
(type II)
Cognitive–linguistic: meaningful minimal contrast
Baker and 2 Subject 1: 57 Single-subject 1–12 45 min Twice weekly 1–6 weeks Probe Percentage correct SCED 7 0.001c
McLeod Subject 2: 52 studies—case 2–32/SLP 2–16 weeks conversation production of
(2004), report, A–B, trained cluster
Australia multiple baseline
design (type IV)
Dodd and Iacono 7 36–57 Case series pre-post- 3–40/SLP n.a. Weekly Average 23.6 Spontaneous PCCb SCED 6 –1.362c
(1989), intervention weeks speech (during Phoneme inventory
Australia design (type IV) play) Process analysis
RIUb

Robb et al. 1 48 Case study: single 20/SLP 45 min Twice weekly 10 weeks Speech sample Percentage accuracy SCED 6 Insufficient data
(1999), USA subject pre-post- Probe list Vowel inventory
intervention PVCb
design (type IV) Acoustic analyses of
vowels (duration,
fundamental
frequency)

Continued
Yvonne Wren et al.
Table 2. Continued

Number of child
participants (number No. of therapy Effect size Cohen d
Reference and of children in each Age range Study design (type of sessions/agent of Length of each Frequency of Duration of type of speech Analysis used to PEDro-P/SCED unless otherwise
country of origin group, if applicable) (months) evidencea ) delivery session (min) sessions intervention sampled measure change score specified

Cognitive–linguistic: complexity approaches


Gierut (1989), 1 55 Case study, pre-post- 23/SLP 30 min Twice weekly 11.5 weeks Probe lists Percentage accurate SCED 8 Insufficient data
USA intervention production of target
design (type IV) phonemes
Gierut (1990), 3 49–58 Alternating n.a./SLP 60 min Three times a n.a. Probe list Percentage accuracy SCED 9 Figures are of
USA treatment week correct on probe list insufficient
design—multiple resolution to
baseline design extract data
(type III-3)
Gierut and 2 48–56 Single-subject 12/SLP 60 min Three times per About 7 weeks Probe Percentage accuracy SCED 6 Figures are of
Systematic review of speech interventions

Champion studies—multiple week correct on probe list insufficient


(1999), USA baseline design resolution to
(type III-3) extract data
Gierut et al. 3 43–66 Single-subject Up to 19/SLP 60 min Three times per n.a. Probe list Percentage accuracy SCED 7 Figures are of
(1996), study studies— week correct on probe list insufficient
1, USA alternating resolution to
treatment design extract data
(type III-2)
Gierut et al. 6 41–66 Single-subject n.a./SLP n.a. n.a. n.a. Probe list Percentage accuracy SCED 7 Figures are of
(1996), study studies—multiple correct on probe list insufficient
2, USA baseline design resolution to
(type III-2) extract data
Rvachew and 48 (24, 24) Group 1: Randomized (type II) 12/SLP n.a. Weekly 12 weeks in PPKPb PPKPb PEDro-P 6 –0.1194
Nowak (2001), average 51.46 two blocks Conversation PCCb
Canada Group 2: of six
average 49.63

Production: imitation and drills


Forrest and Elbert 4 59–63 Single-subject n.a./SLP 45 min Twice weekly n.a. Probe list PCCb for target SCED 6 Insufficient data
(2001), USA studies—multiple phonemes
baseline design
(type III-2)
Forrest et al. 10 (5, 5) 40–54 Comparative n.a./SLP n.a. Fortnightly n.a. Probe Percentage accuracy SCED 8 Insufficient data
(2000), USA studies—therapy correct of probe
approach (type
III-3)
Gierut (1996), 7 40–68 Single-subject n.a./SLP 60 min Three times per Average 18 Probe Change in phonemic SCED 6 Insufficient data
USA studies—multiple week weeks inventory
baseline design
(type III-2)
Gierut and 1 53 Single-subject 19/SLP 60 min Three times per 19 Probe list Percentage accuracy SCED 6 Insufficient data
Champion studies—multiple week correct on probe list
(2000), USA baseline design
(type III-2)

Continued
455
456

Table 2. Continued

Number of child
participants (number No. of therapy Effect size Cohen d
Reference and of children in each Age range Study design (type of sessions/agent of Length of each Frequency of Duration of type of speech Analysis used to PEDro-P/SCED unless otherwise
country of origin group, if applicable) (months) evidencea ) delivery session (min) sessions intervention sampled measure change score specified

Gierut and 8 40–75 Single-subject n.a./SLP 60 min Three times per n.a. Probe list Percentage accuracy SCED 9 IRDd —between
Champion studies—multiple week correct on probe list 84% and 100%
(2001), USA baseline design
(type III-2)
Gierut and 2 47–62 Single-subject n.a./SLP 60 min Three times per Average of 16 Probes Phoneme inventory SCED 6 Insufficient data
Morrisette studies—multiple week weeks
(1996), USA baseline design
(type III-2)
Winner and 4 46–68 Single-subject 25/SLP 30 min Three times per 8 weeks Speech sample Percentage correct SCED 7 IRDd —between
Elbert (1988), studies—multiple week Probe list scores of target 50% and 100%
USA baseline design Spontaneous sounds
(type III-2) speech (picture
description)
Integrated approaches: combined
Almost and 26 (13, 13) 33–61 Group studies— 14–29/SLP 30 min Twice weekly 7–15 weeks GFTAb Single words PEDro-P 9 0.0004
Rosenbaum randomized (type APP-Rb Number of errors
(1998), II) Standardized test PCCb
Canada of single words
Conversational
speech

Hart and 3 43–59 Single-subject 12/SLP 30 min Twice a week 6 weeks HAPP-R 3b Process analysis SCED 8 IRDd —between
Gonzalez studies—multiple Spontaneous Percentage sample 0% and 100%
(2010), USA baseline design speech sample correct
(type III-2)
McIntosh and 3 36–45 Single-subject pre- Between 12 and 30–40 min Twice weekly Between 6 and Single word PVCb SCED 6 –42.187c
Dodd (2008), post-intervention 38/SLP 19 weeks naming test PCCb
Australia design (type IV) (average (DEAPb PPCb
12.8 weeks) phonology Percentage
subtest) inconsistency
Connected
speech task
(DEAPb )
Repeated
production of
words
(DEAPb —
inconsistency
subtest)

Continued
Yvonne Wren et al.
Systematic review of speech interventions 457
The studies provide mixed evidence for this approach:

APP-R = Assessment of Phonological Processes—Revised (Hodson 1986); DEAP = Diagnostic Evaluation of Articulation and Phonology (Dodd et al. 2002); GFTA = Goldman–Fristoe Test of Articulation (Goldman and Fristoe 1969, 2000);
HAPP-R = Assessment of Phonological Processes—Revised (Hodson 2004); PCC = per cent consonants correct; PPC = per cent phonemes correct; PVC = percentage vowels correct (Shriberg and Kwiatkowski 1982); PPKP = productive
Effect size Cohen d
unless otherwise

Insufficient data
Almost and Rosenbaum (1998) showed a positive ef-

specified
fect of active therapy in a group study while the re-

0.0477
maining three studies reported case studies with varying
patterns of response from individuals. Unspecified ap-
PEDro-P/SCED

proaches were used in Glogowska et al. (2000) where no


differences overall were found on the phonology score
score

PEDro-P 8
SCED 8

between control children and those receiving standard


treatment. However, on a secondary outcome, a signifi-
cantly greater proportion of children receiving treatment
phonemic processes
individual targeted

compared with the watchful waiting group improved


Analysis used to
measure change

Percentage use of

their phonology such that they no longer satisfied the


original phonology eligibility criteria for the trial.
Error rate

phonological knowledge profile (Gierut et al. 1987); Psycholinguistic Framework (Stackhouse and Wells 1997); RIU = relative influence on unintelligibility (Dodd and Iacono 1989).
Delivery of intervention
type of speech

(spontaneous

Notes: a National Health and Medical Research Council (NHMRC) (2007) evidence hierarchy: designations of ‘levels of evidence’ according to the type of research question.

All studies included in the review used interventions that


sampled

naming)
picture
Probe list

were delivered by speech and language therapists. Several


Unclear

studies did not provide information on the number and


length of intervention sessions; however, where they did,
2–4.5 months

8.4 months
intervention
Duration of

the range was from three to 67 sessions lasting between


1–9 months

Effect size was calculated using a within-subject design and online calculator from http://www.cognitiveflexibility.org/effectsize/effectsizecalculator.php/.
Average of

30 and 60 min.

Assessment measures used


Frequency of

Once a month

IRD = improvement rate difference, a method of calculating the effect size for single-subject experimental designs (Parker et al. 2011).
sessions
Table 2. Continued

Speech measurement in the reviewed studies was carried


out for one or more of three purposes: to confirm eligi-
n.a.

bility for participation in the study; to identify targets


Length of each
session (min)

for intervention; or to measure change in response to in-


Average of
47 min

tervention (outcome measure). Three studies, all within


the subcategory of phoneme perception approaches, also
n.a.

measured change in speech perception (Wolfe et al.


sessions/agent of
No. of therapy

2003, Rvachew et al. 2004, Rvachew 1994). Speech out-


delivery

6.2 h/SLP

put was collected using published assessments (Hart and


2–32/SLP

Average

Gonzalez 2010, McIntosh and Dodd 2008, Rvachew


1–67

and Nowak 2001), confrontation picture-naming tasks


Study design (type of

devised for the study (Saben and Ingham 1991, Winner


studies—multiple

therapy approach
baseline design

and Elbert 1988), and spontaneous continuous speech


evidencea )

randomized
(type III-2)
Single-subject

Comparative

samples (Dodd and Iacono 1989, Hart and Gonzalez


studies—

(type II)

2010, Saben and Ingham 1991, Rvachew 1994,


Rvachew et al. 2004, Winner and Elbert 1988, Yoder et
al. 2005). In all studies, reliability of the transcriptions
Subject 1: 52
Subject 2: 45
Age range
(months)

was reported using point-to-point agreement for two


Group 1:

Group 2:
18–42

24–42

transcribers, from between 20% and 100% of data col-


lected. Some studies used a combination of two or three
approaches to collecting speech samples. Several studies
participants (number

group, if applicable)
of children in each
Number of child

also used picture naming as part of a probe testing proto-


159 (71, 84)

col (Baker and McLeod 2004, Forrest et al. 2000, Forrest


Integrated approaches: unspecified
2

and Elbert 2001, Gierut 1989, 1990, 1996, Gierut et al.


1996, Gierut and Champion 1999, 2000, Robb et al.
1999, Saben and Ingham 1991, Wolfe et al. 2003).
country of origin

Glogowska et al.

In terms of analysis of the speech samples col-


(1991), USA

(2000), UK
Reference and

lected, those studies that included published assessments


Ingham
Saben and

within their assessment protocol typically used the anal-


ysis procedures which accompanied those tools. These
d
b

c
458 Yvonne Wren et al.
included process analysis (Assessment of Phonologi- evidence forward. As a counter to the inclusion of studies
cal Processes—Revised; Hodson 1986, 2004), phone- with lower-graded evidence, the quality appraisal tools
mic or phonetic inventories (Productive Phonological were used to identify studies with the most robust oper-
Knowledge Profile; Gierut et al. 1987), percentage ationalizations of these designs and reporting processes.
phonemes/consonants/vowels correct (Diagnostic Eval- It should be noted, however, that where higher-
uation of Articulation and Phonology; Dodd et al. graded study designs were used, results could shed a fur-
2002, Shriberg and Kwiatkowski 1982), and accuracy ther light on lower-graded designs. For example, whereas
of production (Goldman–Fristoe Test of Articulation; the studies by Gierut (1989, 1990, 1996) showed a pos-
Goldman and Fristoe 2000). Where spontaneous speech itive outcome for the complexity approach in single case
samples, confrontation picture naming or probe lists designs, Rvachew and Nowak (2001) found that greater
were used, a number of analyses were carried out, as change was observed in children who received input
detailed in table 2. following a developmental rather than a complexity ap-
proach to intervention in a higher-graded group study.
Similarly, the group study carried out by Almost and
Discussion
Rosenbaum (1998) provides more convincing evidence
This systematic review of the literature has considered for their combined approach to intervention in compar-
the evidence for a range of interventions for preschool ison with the case studies reported by others within this
children with SSD within a model in which interven- category of interventions.
tions were classified based on the nature of the proce- The data-extraction process revealed that many stud-
dures used to effect change. In total, 55 papers were ies did not report complete data regarding dosage, but
identified based on clearly defined search criteria. Fol- where these were reported, there was a wide range in the
lowing quality appraisal, 25 papers reporting 26 studies number of sessions provided (3–67). However, there
were appraised as robust enough to be included in the were no clear patterns to the dosage provided within the
final review. These 26 studies were then mapped onto categories and subcategories of interventions. Rather,
the model of interventions according to the description where it was reported, a wide range of number, frequency
of the procedures within each paper. and duration of intervention sessions were offered. Lack
of consistency in the provision of intervention makes it
harder to compare across interventions and to determine
Description of the review
the relative benefit of each.
While some previous reviews have limited their enquiry With regards to measuring outcomes, a range of tools
to children with phonological problems only (Baker and were used to assess speech output including published
McLeod 2011), this review included any study that tar- assessments, picture-naming tasks and spontaneous con-
geted increased accuracy of speech production or ar- tinuous speech samples. As with dosage, there were no
ticulation, encompassing both phonological and speech clear patterns within the categories and subcategories
motor interventions. This was important given the aim with regard to outcome data collection and analysis.
of synthesizing the evidence for clinicians who will be Thus, a narrative synthesis has been used rather than
faced with a broad spectrum of children with SSD in an attempt made at a meta-analysis where the measures
practice (Broomfield and Dodd 2004, Shriberg et al. differed widely. The exception to this was the subcate-
2005). gories of imitation and drill and complexity approaches
The review included a range of research designs which both relied heavily on probe word lists to test
and did not limit itself to randomized control trials, outcomes. However, these studies were predominantly
though most were at level III of the NHMRC Evidence carried out by two groups of researchers, which may ex-
Hierarchy (NHMRC 2007) and, therefore, were ei- plain the tendency towards the same measurement tools
ther pseudo-randomized controlled trials or compara- rather than indicating consensus across research groups
tive studies with or without concurrent controls. Pre- in favour of any particular measure.
vious reviews (Law et al. 2003, Lee and Gibbon 2015,
Morgan and Vogel 2008) have followed more restrictive The model for classifications of interventions
criteria with regards to study design. However, in order
for SSD
to reflect the growing evidence base and the potential for
lower-graded studies to develop into larger studies with The classification model used to classify those inter-
more robust research designs, the decision was made to ventions included in the review was developed us-
include studies with a lower level of evidence, as defined ing a bottom-up approach based on interventions de-
by the NHMRC (2007). This allowed an investigation scribed by clinicians in practice (Roulstone and Wren
of the current level of evidence for interventions and 2001). The model proposes five main categories (en-
a clear picture regarding what is required to take the vironmental, auditory–perceptual, cognitive–linguistic,
Systematic review of speech interventions 459
production and integrated) that distinguish interven- supported by a number of good-quality studies, but
tions according to where change, which will lead to im- the level of evidence represented in each of these studies
proved speech output, is expected to occur. The subcat- is low based on the NHMRC (2007) classification of
egories attempt to capture more precisely what is being levels of evidence. Across these three subcategories of
asked of the child in order to effect change. An exhaus- intervention procedure, the highest graded study was at
tive list of possibilities is not presented, however, and level III-2: a comparative study with concurrent con-
the model will undoubtedly evolve as new intervention trols. This is comparable with a classification of indica-
procedures emerge and the evidence base grows. tive evidence based on the ‘What Works’ database of
interventions (Law et al. 2015). The fact that there are
studies with higher-grade evidence adds credence to the
Mapping the evidence to the model
findings for the category or subcategory as a whole, but
Categorization of studies to the model was complex. there is still a need for more studies using a higher level
Many of the studies included could have been cate- of evidence methodologies to strengthen the evidence
gorized under the subcategory of ‘combined’, e.g., all base for these types of intervention. This fits with the
three of the studies listed under auditory perceptual findings of Baker and McLeod (2011) who commented
included production activities. However, studies were on the need for higher levels of scientific rigour and
categorized according to the specific element of the in- the importance of replication research to build on the
tervention being investigated. Some studies added com- findings of lower-graded studies.
ponents to their interventions during the course of their Higher-grade evidence was identified in the re-
study making it difficult to assess the particular contribu- view for three studies: one using phoneme percep-
tion to outcome relative to the original aim of the study tion (Rvachew et al. 2004), one that used a com-
(McIntosh and Dodd 2008, Saben and Ingham 1991). bined approach (Almost and Rosenbaum 1998); and a
Further difficulties arose concerning the amount of in- third where the intervention procedure was unspecified
formation regarding intervention procedures provided (Glogowska et al. 2000). All three studies were random-
in the paper. With more information, it is possible that ized controlled trials with large sample sizes relative to
some of the studies reported would be re-categorized most of the other studies (34, 26 and 26 respectively).
into a different group. Given that a range of interventions was used within these
The majority of studies in the review focused on studies, this suggests there is agreement that a variety of
just three of the 11 subcategories of the model: imi- approaches to intervention can be effective for children
tations and drill (seven studies), meaningful minimal with SSD (Lancaster et al. 2010).
contrasts (three studies) and complexity (six studies).
The remaining studies covered a further four cate-
Clinical implications
gories/subcategories. Thus, no studies were identified
for four of the subcategories of the model. It is possible The review and categorization of the studies onto the
that no evidence is available for each of these subcate- model of interventions, as illustrated in figure 3, pro-
gories or that the evidence that is available was not robust vides an easy reference for clinicians regarding which
enough to be included in the review, despite the broader interventions have evidence to support them. The cate-
inclusion criteria of this review compared with others. gories of intervention can also be mapped onto the needs
Rather than suggesting that those subcategories with no of individual children. For example, where assessment
studies in the review are ineffective, the more accurate has shown that a child’s presenting SSD is associated
conclusion would be that currently there is no strong with problems in auditory processing, the interventions
evidence to support these intervention procedures with described by Wolfe et al. (2003) and Rvachew (1994)
preschool-aged children. and Rvachew et al. (2004) could be useful. The de-
Some degree of supporting evidence was identified scriptions in the individual papers regarding both the
for seven of the intervention categories and subcate- activities carried out and the manner of delivery, in
gories in the model. These covered all the five main terms of number and frequency of sessions, can assist
categories and a range of subcategories: environmen- in providing information for an evidence-based service.
tal approaches; phoneme perception; guidance on pho- Similarly, if assessment reveals that a child’s needs appear
netic placement/manner; imitations and drill; contrasts; to be in the areas of cognitive–linguistic processing or
complexity; combined and unspecified approaches. The production skill, the relevant studies in each category
number of quality studies varied across these subcat- can be used to guide the plan for intervention. Though
egories, from just one each for ‘environmental’ and more comparative studies need to be completed to deter-
‘guidance on phonetic placement/manner’ to seven for mine the degree to which some approaches are more ef-
imitation and drill. Three subcategories in the model, fective or efficient than others within categories, the abil-
imitations and drill, contrasts and complexity, were ity to identify specific approaches mapped to children
460 Yvonne Wren et al.
with specific needs is invaluable in the clinical context higher-graded methodological studies which will pro-
when time for considering the literature to cover a broad vide more robust information on which approaches or
range of presentations for SSD is limited. combination of approaches are most suitable to use with
this client group.
Strengths and limitations of the study
Acknowledgements
The systematic review had a specific remit to look at
the evidence base related to intervention for SSD with ‘Child Talk’—What Works presents independent research commis-
sioned by the National Institute for Health Research (NIHR) under
preschool children (2;00–5;11). Studies with 20% or its Programme Grants for Applied Research funding scheme (grant
more of children outside the specified age range were number RP-PG-0109-10073). The views expressed here are those of
not included. The criteria for inclusion meant that some the authors and not necessarily those of the National Health Service
frequently cited papers were not included in the review. (NHS), the NIHR or the Department of Health. Child Talk was
The reasons for non-inclusion were most often related a large programme and we are indebted to our co-applicants and
members of the team for their wisdom, support and input to the
to the age range of the children in the sample or a low programme as a whole, and to their influence on all outputs from
score on the quality appraisal tools used. Some stud- the programme: Lydia Morgan, Naomi Parker, Rebecca Coad, Julie
ies were also excluded because the sample used in the Marshall, Linda Lascelles, Jane Coad, Norma Daykin, Alan Emond,
study included children with known concomitant dif- Jenny Moultrie, Tim Peters, Jon Pollock, Jane Powell, Cres Fernandes
ficulties such as cleft palate or hearing loss or because and William Hollingworth. Declaration of interest: The authors re-
port no conflicts of interest. The authors alone are responsible for
outcomes were not reported for speech (see appendices C the content and writing of the paper.
and D for excluded studies). Moreover, as the outcome
measure needed to include speech output, the review
did not include interventions that focused on prosodic Notes
skills or speech perception or other underlying speech 1. See http://speechbite.com/rating-research-quality/outline-rating-
processing skills unless these were included alongside a training-program/.
measurement of speech output. 2. See https://www.campbellcollaboration.org/escalc/html/Effect
SizeCalculator-SMD-main.php/.
3. See http://www.cognitiveflexibility.org/effectsize/.
Conclusions 4. See http://www.prisma-statement.org (accessed on 3 March
2016).
To summarize, there is evidence to support certain types
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Systematic review of speech interventions 463
WREN, Y., 2005, An evaluation of the use of computers in phonology 36. Language Development/
therapy. Unpublished PhD thesis. 37. exp Nonverbal Communication/
WREN, Y., HAMBLY, H. and ROULSTONE, S., 2013, A review of 38. Communication Disorders/
the impact of bilingualism on the development of phonemic
awareness skills in children with typical speech development. 39. maternal responsiveness.tw.
Child Language Teaching and Therapy, 29, 11–25. 40. directiveness.tw.
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45. or/13-44
Appendix A: Search terms used in a systematic 46. exp Mental Retardation/
47. exp child development disorders, pervasive/or as-
review of interventions for speech-sound
perger syndrome/
disorder (SSD) in preschool children 48. Cleft Palate/or Cleft Lip/
1. exp Pediatrics/ 49. Otitis Media with Effusion/
2. exp CHILD/ 50. exp Hearing Loss/
3. exp INFANT/ 51. exp Blindness/
4. child$.mp. [mp = title, original title, abstract, name 52. Stuttering/
of substance word, subject heading word] 53. Aphonia/
5. infant$.mp. [mp = title, original title, abstract, 54. exp Pain/
name of substance word, subject heading word] 55. Crying/
6. (paediatric$ or pediatric$).mp. [mp = title, origi- 56. exp Analgesia/
nal title, abstract, name of substance word, subject 57. Reading/
heading word] 58. exp Dyslexia/
7. toddler$.mp. [mp = title, original title, abstract, 59. Cerebral Palsy/
name of substance word, subject heading word] 60. (alternative and augmentative communication).mp.
8. boy$.ti,ab. [mp = title, original title, abstract, name of sub-
9. girl$.ti,ab. stance word, subject heading word]
10. (school child$ or schoolchildren$).ti,ab. 61. ‘alternative and augmentative communication’.mp.
11. (pre school$ or preschool$).ti,ab. [mp = title, original title, abstract, name of sub-
12. or/1-11 stance word, subject heading word]
13. speech disorder$.ti,ab. 62. exp aged/
14. speech intelligibility$.ti,ab. 63. geriatrics/
15. speech therap$.ti,ab. 64. or/46-63
16. language therap$.ti,ab. 65. (12 and 45) not 64
17. speech development.ti,ab. 66. randomized controlled trial.pt.
18. speech delay.ti,ab. 67. controlled clinical trial.pt.
19. language disorder$.ti,ab. 68. randomized controlled trials/
20. language development disorder$.ti,ab. 69. random allocation/
21. sign language$.ti,ab. 70. double blind method/
22. child$ language.ti,ab. 71. single blind method/
23. language therap$.ti,ab. 72. clinical trial.pt.
24. language development.ti,ab. 73. exp clinical trials/
25. language delay.ti,ab. 74. (clin$ adj25 trial$).tw.
26. nonverbal communication.ti,ab. 75. ((singl$ or doubl$ or trebl$ or tripl$) adj25 (blind$
27. non verbal communication.ti,ab. or mask$)).tw.
28. communication development.ti,ab. 76. placebos/
29. exp Speech Disorders/ 77. placebo$.tw.
30. speech Intelligibility/ 78. random$.tw.
31. ‘rehabilitation of speech and language disorders’/or 79. research design/
language therapy/or speech therapy/ 80. ‘comparative study’/
32. Language Development Disorders/ 81. exp evaluation studies/
33. Language Disorders/ 82. follow-up studies/
34. Sign Language/ 83. prospective studies/
35. Child Language/ 84. (control$ or prospectiv$ or volunteer$).tw.
464 Yvonne Wren et al.
85. (control$ or prospectiv$ or volunteer$).tw. 88. ‘human’/
86. or/66-85 89. 87 not 88
87. ‘animal’/ 90. 86 not 89

Appendix B: Databases searched, number of results and search date

Databasea Search interface Search results Search date

MEDLINE Ovid 8374 6 December 2011


EMBASE Ovid 9663 6 December 2011
Cumulative Index to Nursing and Allied Health Literature (CINAHL) EBSCOhost 8976 2 December 2011
PsycINFO EBSCOhost 9107 11 January 2011
Cochrane Database of Systematic Reviews (CDSR) The Cochrane Library 255 13 January 2012
Database of Abstracts of Reviews of Effects (DARE) The Cochrane Library 0 13 January 2012
NHS Health Technology Assessment database The Cochrane Library 0 13 January 2012
Cochrane Central Register of Controlled Trials (CENTRAL) The Cochrane Library 0 13 January 2012
Science Citation Index Web of Knowledge 5787 13 January 2012
Social Science Citation Index Web of Knowledge 0 13 January 2012
International Bibliography for the Social Sciences ProQuest 0 25 November 2011
Applied Social Sciences Index and Abstracts (ASSIA) ProQuest 1799 25 November 2011
Sociological Abstracts ProQuest 3800 25 November 2011 ProQuest 3800 25 November 2011
Social Services Abstracts ProQuest 0 25 November 2011 ProQuest 0 25 November 2011
Educational Resource Information Center (ERIC) ProQuest 4000 26 January 2012
Linguistics and Language Behavior Abstracts ProQuest 3006 20 January 2012
British Education Index ProQuest 464 20 January 2012
The Campbell Collaboration www.campbellcollaboration.org/ 40 13 January 2012

Note: a Databases were searched from the date of inception to the search date.

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Appendix C: Studies excluded at the quality Bryan, A. and Howard, D., 1992, Frozen phonology
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disorder of real word phonology. European Journal of
Adams, C., Nightingale, C., Hesketh, A. and Hall, Disorders of Communication, 27, 343–365.
R., 2000, Targeting metaphonological ability in inter- Dodd, B. and Barker, R., 1990, The efficacy
vention for children with developmental phonological of utilizing parents and teachers as agents of ther-
disorders. Child Language Teaching and Therapy, 16, apy for children with phonological disorders. Aus-
285–299. tralian Journal of Human Communication Disorders, 18,
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