DRUG STUDY
DRUG ORDER
(Generic name, Brand name,
classification, dosage, route,
frequency)
Generic Name: Amlodopine
Brand Name: Norvasc
Classifications:  cardiovascular
agent; calcium channel blocker
Pregnancy Category:C
NURSING
MECHANISM OF ADVERSE EFFECTS OF THE
INDICATIONS CONTRAINDICATIONS RESPONSIBILITIES/
ACTION DRUG
PRECAUTIONS
Amlodipine is a Treatment of mild to moderate Hypersensitivity to CV:Palpitations, flushing  Monitor BP for
calcium channel hypertension and angina. amlodipine. tachycardia, peripheral or facial
blocking agent that edema, bradycardia, chest pain, therapeutic effectiveness.
selectively blocks syncope, postural hypotension. BP reduction is greatest
calcium ion reflux CNS:Light-headedness, fatigue, after peak levels of
across cell headache.
amlodipine are achieved 6–
membranes of GI:Abdominal pain, nausea,
cardiac and anorexia, constipation, dyspepsia, 9 h following oral
vascular smooth dysphagia, diarrhea, flatulence, doses.Monitor for S&S of
muscle without vomiting. dose-related peripheral or
changing serum Urogenital:Sexual dysfunction,
calcium frequency, nocturia. facial edema that may not
concentrations. It Respiratory:Dyspnea. be accompanied by weight
predominantly acts Skin:Flushing, rash. gain; rarely, severe edema
on the peripheral other:Arthralgia, cramps, myalgia.
circulation, may cause discontinuation
decreasing of drug.
peripheral vascular  Monitor BP with postural
resistance, and
changes. Report postural
increases cardiac
output. hypotension. Monitor more
frequently when additional
antihypertensives or
diuretics are added.
 Monitor heart rate; dose-
related palpitations (more
common in women) may
occur.