THEORETICAL MODEL OF METABOLIC PATHWAY

SIMULATION

NAME : N HARSHITHA

REG.NO:191EC158

DEPARTMENT: ECE

INTRODUCTION:

The linked series of chemical reactions within the cell refers to metabolic
pathway. In these reactions, the reactants, products and intermediates are called
metabolites catalyzed by enzymes. In most of the cases , product of one enzyme
acts as the substrate for the next one.

The metabolic network comprise of various metabolic pathways and the

chemical reactions of a cell and the interactions guiding the reactions. It is a
complete set of physiological and metabolic processes helping in the determination
of physiological and biochemical properties of a cell.

1.METABOLIC NETWORK OF LIVER:

The metabolic network of the liver comprises of a list of network pathways.

They are glycolysis, citric acid cycle(kreb’s cycle), oxidative phosphorylation of
pyruvic acid and pentose pahosphate pathway.
 Figure 1 : Metabolic networks in a liver

2.PENTOSE PHOSPHATE PATHWAY

The metabolites of this pentose phosphate pathway are glucose 6-

phosphate, NADP+, NADPH, GSH,GSSG, Fatty acids, 6-Phosphogluconate,
Ribose 5-phosphate, transketolase, transaldolase, Nuleotides, Coenzymes, DNA,
RNA.
 Figure 2: Pentose phosphate pathway

3. RESULT OF SIMULATION

Figure 3: Graph representation the concentration

4.CONCLUSION

Thus, the simulation of metabolic pathways gives us an in depth sight of

molecular mechanisms of a particular organism. It gives us a clarity of the working
of enzymes, their concentration, and an analysis of the entire network.