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doi:10.1111/jpc.

14638

REVIEW ARTICLE

Feeding difficulties in children with autism spectrum disorder:


Aetiology, health impacts and psychotherapeutic interventions
Vincent Zhu1 and Jacqueline Dalby-Payne 1,2

1
Department of General Medicine, Children’s Hospital at Westmead and 2Discipline of Child and Adolescent Health, University of Sydney, Sydney, New
South Wales, Australia

Abstract: Feeding difficulties are common and significant issues for children with autism spectrum disorder and their families. Key features of
autism are intrinsically linked with factors contributing to these children’s feeding difficulties. Following a multidisciplinary assessment to exclude
non-behavioural reasons for the feeding difficulty, there are two mainstay modalities of treatment: operant conditioning and systematic
desensitisation. Currently, evidence points towards operant conditioning as the most efficacious psychotherapy. However, recent research into
cognitive behavioural therapy for older children with feeding difficulties has shown promising results and will be an area to monitor in the coming
years. This review outlines the causes and health impacts and evaluates current evidence supporting the available psychotherapeutic interven-
tions for children with autism spectrum disorder experiencing feeding difficulties.

Key words: autism spectrum disorder; feeding difficulties; selective eating.

Autism spectrum disorder (ASD) is a complex lifelong develop- based management recommendations. Behavioural interventions
mental disorder that involves clinically significant impairment of have been found to be beneficial for certain types of feeding difficul-
social ability in multiple contexts and restricted and repetitive ties;7 however, evidence of the effectiveness of many commonly
patterns of behaviour. The prevalence of autism ranges from 1 to recommended interventions is often lacking. Research comparing
1.5%.1–3 Within the families that have a child with ASD, studies behavioural interventions is limited, often small-scaled and highly
have shown that up to 67% of the parents believe their child to dependent on the treatment provider. This review aims to describe
have strong food preferences.4,5 As children with ASD are more the aetiology of the various types of feeding difficulties, explore the
likely to exhibit refusal behaviours,6 this results in feeding diffi- health and family impacts of restricted eating behaviours and exam-
culties that can impact both the child and the family. ine behavioural therapies available for the management of feeding
Feeding difficulties not only affect the child’s health but have difficulties in children with ASD.
profound effects on the family’s psychological well-being and
dynamics. These harmful effects necessitate the need for evidence- Aetiology of Feeding Difficulties in ASD
Abnormal feeding behaviours in children with ASD often arise
Key Points from the complex interplay of symptoms commonly associated
1 A range of factors may contribute to feeding difficulties, and with autism. The factors for behavioural feeding difficulties in
medical causes should be identified and managed before children with ASD identified by Cumine8 can be grouped into
embarking on a behavioural approach to therapy. three main issues: behavioural rigidity, social impairment and
2 Studies to date indicate that operant conditioning may be sensory processing difficulties. These three issues identified by
more effective than systematic desensitisation therapy, but fur- Cumine are also key symptoms of ASD as described in DSM-5.9
ther research is required. They are described in diagnostic criteria: B2 – Insistence on
3 Cognitive behavioural therapy for older children with feeding sameness, inflexible adherence to routines; A3 – Deficits in devel-
difficulties has shown promising results and will be an area to oping, maintaining and understanding relationships; and B4 –
monitor in the future. Hyper- or hyporeactivity to sensory input. Behavioural rigidity
involves desiring consistency in meal presentation, preparation
and taste. The social impairment mentioned involves anxiety, dis-
ruptive behaviour and deficits for social compliance. The third
Correspondence: Dr Jacqueline Dalby-Payne, Department General
issue is sensory-processing difficulties, which affects how the food
Medicine, The Children’s Hospital at Westmead, Locked Bag 4001, Westmead,
and the entire experience of eating are perceived. Appropriate
NSW 2145, Australia. Fax: +61 29845 0074; email: jacqueline.
dalbypayne@health.nsw.gov.au processing of sensory information allows the brain to be mindful of
useful information while preventing the brain from being inundated
Conflict of interest: None declared.
with useless information. An inability to process the myriad of sen-
Accepted for publication 28 August 2019. sory information received during a meal can impact the

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© 2019 Paediatrics and Child Health Division (The Royal Australasian College of Physicians)
Feeding and autism spectrum disorder V Zhu and J Dalby-Payne

eating experience of children with ASD.10 Twachtman-Reilly et al. and calcium deficiencies have been shown to be significantly
described how deficits in processing auditory, visual, gustatory, more common in children with ASD with feeding difficulties.6
olfactory, tactile, vestibular and proprioceptive sensory information Studies show that, overall, fruit and vegetables was the food
can lead to difficulties in feeding.11 Hyper-responsiveness in audi- group most often neglected, with simple carbohydrates pre-
tory, visual, gustatory, olfactory and tactile senses can lead to an ferred.17,18 This preference for simple carbohydrates is thought
overstimulating environment or meal, which may invoke a fight or to be the main contributor towards a greater tendency for chil-
flight response during mealtimes. Hyporesponsiveness to these five dren with ASD to be overweight.19 This is concerning as over-
senses could result in a disinterested child who would rather par- weight and obese children have been shown to be at increased
take in other activities or request more stimulating food. Hyper- risk of adulthood obesity20 and its associated risks, such as cor-
responsiveness and hyporesponsiveness in proprioceptive senses can onary heart disease.
cause poor body awareness and difficulties with self-feeding. Vestib- As the focus of care can often be on medical issues, it is not
ular hyper-responsiveness can lead to a child who is uncomfortable uncommon to overlook the impact these feeding difficulties
with head movements required to eat certain food, whereas vestib- have on the carers and the other diners in the family.
ular hyporesponsiveness can lead to a restless child. These three fac- Ausderau identified four issues experienced by families with
tors can occur in combination or independently to result in feeding children who have ASD.21 First, families were unable to eat
difficulties in children with ASD. An understanding of how these together at the same time due to attention and consideration
factors contribute to an individual child’s feeding behaviour can required to feed the affected child. Second, mealtime routines
assist with guiding management. were adapted to great lengths to engage the child to eat his or
Feeding difficulty is an umbrella term for feeding problems her food. Adaptations included distracting the child with tele-
that may present in several ways. Discerning the problems caus- vision or playing games. Third, many carers were preparing at
ing the feeding difficulty is the first step in formulating an initial least two meals in case the first was refused. The fourth theme
management plan. A study by Field et al. of 349 children with explored by Ausderau was the impact on siblings. Siblings were
feeding difficulties described five categories: selectivity by texture, required to be a role model and assist with encouraging posi-
selectivity by type (including food neophobia), food refusal, oral tive eating behaviours. It was also reported that siblings some-
motor delays and dysphagia.12 The study also demonstrated that times also imitated the negative behaviours, which gave the
the various feeding problems can coexist. Of the 349 children carer additional stress.21 Overall, it is evident that feeding diffi-
studied, 26 had a diagnosis of autism. By far the most common culties in children with ASD have various impacts on the child
form of feeding problem in children with ASD was selectivity by and the family unit. For these reasons, the establishment of a
type, found in 62%. In comparison, the prevalence of selectivity
by type was 11% in the Down syndrome and cerebral palsy arm.
Although it is not well established why children with ASD were
presenting with selectivity by type more than five times as often, Box 1 Aetiology
it was suggested by Field et al. that this may be due to the differ-
ence in sensory modulation among children with ASD. This the-
1 Behavioural rigidity
ory was demonstrated in further studies that showed poor
Desiring consistent presentation, preparation and taste
olfactory and taste accuracy were related to food selectivity.13,14
2 Social impairment
This underscores the importance of assessing for differences in
Anxiety, disruptive behaviour and deficits for social compliance
sensory processing during the assessment stage to help guide tai-
3 Sensory-processing difficulties
loring of the management plan.
Affects how food tastes, feel and smell
Food refusal was defined as the refusal to eat all or most
food to the point of not meeting energy demands, which is
vastly different from having a highly selective diet that may
lead to specific micronutrient deficiencies while sustaining
energy consumption. Of the three children with ASD who had
food refusal, all of them had gastro-oesophageal reflux, thus
highlighting the importance of excluding medical issues in chil- Box 2 Impacts
dren who are exhibiting feeding difficulties, particularly in
cases of food refusal (Box 1).
1 Nutritional deficiencies
Particularly vitamin A, vitamin D and calcium
Health and Psychosocial Impacts of 2 Weight gain
Feeding Difficulties in Children with ASD Likely due to tendency to prefer simple carbohydrates
3 Carer stress
Feeding difficulties in children with ASD can have a significant Preparation of multiple meal options
impact on the child’s health. As food selectivity is the most Un-co-operative child
common type of feeding difficulty in children with ASD, they 4 Relationship strain on family unit
are at risk of nutritional deficiencies, with resulting diverse Family members unable to eat together
health impacts. Studies have demonstrated that children with Negative influence on siblings
ASD had a greater number of nutritional deficiencies compared
to typically developing children.6,15,16 Vitamin A, vitamin D

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© 2019 Paediatrics and Child Health Division (The Royal Australasian College of Physicians)
V Zhu and J Dalby-Payne Feeding and autism spectrum disorder

strategy to deal with feeding difficulties in children with ASD is anxiety disorders with pharmacotherapy.23 However, a Cochrane
paramount (Box 2). review in 2013 investigated the use of selective serotonin reup-
take inhibitors (SSRIs) for the management of ASD symptoms in
children.24 The review included five RCTs on children with ASD.
Assessment
Overall, they showed no significant benefit for the management
To evaluate the cause of the feeding difficulty and to develop a of core ASD features (problems with behaviour, communication
treatment plan, a multidisciplinary team should ideally be and social interaction), as well as the non-core aspects, such as
involved. It is important to remember that it is not uncommon obsessive–compulsive behaviour and self-injurious behaviour.
for children to have multiple causes for their feeding difficulty,12 Unfortunately, not enough data were gathered to make a conclu-
hence the importance of engaging a multidisciplinary team for sion of whether or not SSRIs were useful for anxiety or feeding
assessment. This team should include a dietitian, medical officer, difficulties in children with ASD. As pharmacotherapy such as
speech pathologist, occupational therapist and psychologist or SSRIs has been found to be useful in managing anxiety in chil-
behavioural therapist. A dietitian’s role is to assess for atypical dren, and anxiety is known to contribute to feeding difficulties in
growth or nutritional deficiencies in the child’s diet and provide children with autism, SSRIs may be worth considering for the
dietary goals for management. A medical review is crucial to management of feeding difficulties in children with ASD. Never-
assess the medical causes of feeding difficulties and complications theless, the effectiveness of SSRIs in this particular population is
such as constipation and clinically evident nutritional deficien- not clear from current available evidence. As pharmacotherapy
cies.12,22 Medical causes such as gastro-oesophageal reflux dis- such as SSRIs have been found to be useful in managing anxiety
ease, dysphagia and eosinophilic oesophagitis should always be in children and anxiety is known to contribute to feeding difficul-
considered, particularly in cases where food refusal has been ties in children with autism, SSRIs could be considered though
identified as a factor of the feeding difficulty. A speech patholo- their effectiveness in this particular population is not clear from
gist can assess for oro-motor dysfunction. An occupational thera- current available evidence.
pist can examine sensory-processing and motor skills involved
with feeding. The nature and symptoms of the different compo-
nents of hyper-responsiveness and hyporesponsiveness have
Psychotherapies
been described,11 and an occupational therapist can assess for Literature review and data gathering
these by direct observation of the child, as well as by parent
report. A psychologist will be able to assess for the contribution For evidence regarding psychotherapies, multiple databases,
of behavioural components such as rigidity and anxiety to the including Cochrane, Medline, PubMed, Embase and PsycINFO,
child’s feeding difficulty. The frequency of multiple causative fac- were used with a combination of the following search terms:
tors contributing to a child’s feeding difficulties and the impor- autism, children, feeding, operant conditioning (OC), escape
tance of identifying these factors to formulate appropriate extinction (EE), positive reinforcement, applied behavioural anal-
management strategies makes a multidisciplinary approach ysis (ABA), systematic desensitisation, sequential oral sensory
essential. and cognitive behavioural therapy (CBT).
The search yielded no meta-analyses and very few high-
quality studies. Several RCTs cited involved a small participant
General Management population. Much of the evidence was case reports and case
Regardless of the cause of the feeding difficulties, it is important series. For the purpose of this literature review, single case
to first address the nutritional requirements of the child. Ade- reports were excluded, and RCTs and case series were included
quate nutrition is important for growth and development. A child with preferences given to higher-quality studies where available.
with an inadequate intake or restricted diet can be supplemented
with specialised child formulas or micronutrient supplements Operant conditioning
while the management plan is underway. Medical causes of feed-
ing difficulties should be identified and managed as behavioural OC is a process of influencing behaviours by reinforcing (reward-
interventions are unlikely to be successful unless they are ing) desired behaviours and punishing undesired behaviours.
addressed. Other medical issues such as neurological deficits or Positive reinforcement for good feeding behaviours generally
anatomical abnormalities, which may cause dysphagia, are involves provision of a toy, a desired food or praise given either
diverse and not the most common cause of feeding difficulties in continuously throughout the meal (non-contingent positive rein-
children with ASD. Their diagnosis and management will require forcement) at the same time as good behaviour (simultaneous
specialist medical assessment. Children with ASD found to have presentation) or after good behaviour is displayed (differential
dysphagia or oro-motor delay may benefit from therapy with a positive reinforcement).
speech pathologist. The speech pathologist may work to improve A vital aspect of OC is not to provide negative reinforcement –
the muscle co-ordination, recommend an altered diet or teach that is, rewarding behaviour that is undesired, such as allowing a
behavioural and postural strategies to optimise swallowing. child to not eat when they cry or engage in other disruptive
Where anxiety is seen to be a significant issue, a Cochrane review behaviours. The practice of avoiding this detrimental response to
in 2009 investigated the benefits of pharmacotherapy in children negative behaviour is known as EE. A well-known method of EE
with anxiety disorders. The systematic review included 22 short- for feeding difficulties would be non-removal of the spoon. This
term randomised controlled trials (RCTs) on children without involves holding the spoon in front of the child’s mouth unyield-
ASD and showed that there was a benefit in treating paediatric ingly until he or she eats the food. This removes the avenue of

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© 2019 Paediatrics and Child Health Division (The Royal Australasian College of Physicians)
Feeding and autism spectrum disorder V Zhu and J Dalby-Payne

escape for the child, thus ceasing reinforcement of the negative 7 and 12 years are able to participate in the basic cognitive tasks
behaviour. Numerous studies have shown its benefit in both chil- involved in CBT37 and that, with some modification to traditional
dren with and without ASD for feeding difficulties.25–29 CBT, it can an effective therapy for anxiety in children with ASD.38
ABA utilises OC to promote good feeding behaviour and dis- Despite this, research into the efficacy of CBT to manage feeding dif-
courage poor feeding behaviour. It is well established that ABA is ficulties in children with ASD is limited. A pilot trial was performed
beneficial for the management of behavioural issues in children in 2017 utilising CBT over 14 weeks for feeding difficulties in 11 chil-
with ASD.30 A technical review of 112 studies reports a beneficial dren with ASD aged between 8 and 12 with a verbal intelligence
outcome 70% of the time and that approximately two-thirds of quotient ≥80. CBT was provided on a weekly basis to the carers and
ABA interventions exhibited strong evidence for generalisation to the children, with sessions running for 90 min each. Results of the
other aspects of the participant’s life.29 Various ABA techniques study were measured qualitatively with satisfaction questionnaires.
have been shown to be beneficial for many types of feeding diffi- Although it was not clearly established what the needs of the family
culties in children with ASD.7,25,30–32 Thus, ABA has been one of were, half of the participants believed the program met all their
the most favoured psychotherapeutic treatments for feeding diffi- needs, 38% believed most of their needs were met, and 12%
culties in the past. believed only a few of their needs were met.39 With these promising
results, we can expect further research into the use of CBT in man-
aging feeding difficulties in older children with ASD in the future.
Systematic desensitisation
Systemic desensitisation (SD) is centred around the theory that Conclusion
children with ASD are more likely to have sensory modulation
deficits,33 which may negatively impact their eating experience.10 Feeding difficulties in children with ASD is an important issue
The Sequential Oral Sensory approach (SOS) is a widely pro- as it adversely impacts the child’s health and the family’s expe-
moted SD programme in Australia for children with ASD and rience at mealtimes. As there is a variety of causes for feeding
feeding difficulties. SOS attempts to gradually desensitise a child difficulties, a multidisciplinary approach to assessment and
to eat a greater range of food at reasonable quantities by logical management is essential to formulate an appropriate manage-
and stepwise introduction of food. This would suggest that SOS is ment strategy. Medical causes should be identified and man-
more effective in children who have been assessed to have aged before embarking on a behavioural approach to therapy.
hyper-responsive dysfunction; however, there are no published Studies examining the use of psychotherapies for managing
studies of SOS just targeting children with sensory modulation selective eating in ASD are limited. Therapy options include OC
deficits. This stepwise introduction of food is significantly differ- and systematic desensitisation for younger children and CBT for
ent from tactics used by OC as it allows the child to lead the pro- children over 8 year of age. ABA, a form of OC therapy, is a
gression of therapy. Children are exposed to their target foods well-established discipline with the most evidence for its use in
through sight, touch, play and taste before actual ingestion. feeding difficulties for children with ASD. Therapies utilising
Several studies have been conducted comparing OC and SD a systematic desensitisation approach have been gaining pop-
therapy for children with ASD. The largest study was a ularity in recent years. Although both ABA and systematic
randomised clinical trial that involved 68 participants with feed- desensitisation have been shown to be effective therapies for
ing difficulties, 33 of whom had ASD.34 This study showed that feeding difficulties in children with ASD, studies overall indicate
children in the OC group had a greater increase in total number that ABA may be more effective. Preliminary results show that
of unprocessed fruits and vegetables consumed than the SD the use of CBT in older children with ASD may be effective for
group. Although a control was not used for this study, it is impor- managing problematic feeding behaviours, and further research
tant to note that both arms of this study benefited from the inter- into this form of therapy is warranted. Given the limited evidence
vention. A randomised trial of six children with ASD in 2010 for the efficacy of the various psychotherapeutic treatment
showed that all three children undergoing ABA therapy demon- options for managing behavioural feeding difficulties in children
strated increased acceptance of food, while all three children receiv- with ASD, further research is required. It is hoped that the result
ing SD had acceptance rates at zero or near zero.35 A case series will be a better understanding of the use of these therapies and
involving two typically developing children identified as having improved nutritional and psychological outcomes for children
sensory-processing issues showed that sensory integration therapy with ASD and their families.
(involving sensory desensitisation with escape, similar to SOS) pro-
duced little to no benefit for the children, but then, EE with non- Acknowledgement
contingent reinforcement increased the acceptance rate to 96% in
one child and 100% in the other.36 The results of these studies sug- We thank Wendy Birks, Laura Swift and Jane Pettigrew, Multi-
gest that OC is more effective than SD therapy, but it is important disciplinary Feeding Team, The Children’s Hospital at Westmead,
to note that these are small studies and that further research is for review of manuscript.
required to fully evaluate their efficacy in children with ASD.

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V Zhu and J Dalby-Payne Feeding and autism spectrum disorder

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