1.

  Biological molecules (proteins) which catalyze a biochemical reaction and remain unchanged
after completion of reaction are called
A. Cofactor B. Coenzymes

C. Activator D. Enzymes

Which statement about enzyme is incorrect:

Some of them consist solely of protein with They catalyze a chemical reaction without
A. B.
no non protein part. being utilized.

They without their cofactor are called

C. All enzymes are fibrous Proteins. D.
apoenzyme.
In which of the following location enzymes controlling cellular respiration are present?
A. Nucleus B. Chlorophast

C. Milochondria D. Ribosome

An activated enzyme consisting of polypeptide chain and a cofactor is called:

A. Apoenzyme B. Holoenzyme

C. Activated enzyme D. Both b and c

Which one forms the raw material for coenzymes?
A. Vitamins B. Carbohydrates

C. Proteins D. Metals
A cofactor made of inorganic ion which is detachable is called
A. Prosthetic group B. Coenzyme

C. Activator D. Cofactor
Enzymes _________ the activation energy of a chemical reaction
A. Increases B. Decreases

Increases or decreases depending upon

C. Does not effect D.
individual enzyme
A three dimensional dcavity bearing a specific charge by which the enzyme reacts with its substrate
is called
A. Active site B. Binding site

C. Catalytic site D. Allosteric site

Which step causes activation of catalytic site of an enzyme?
A. Change in pH of the surroundings. B. Formation of Enzyme Susstrate complex.

C. Change in the charge of the active site. D. Change in temperature

Lock and Key model was proposed by

A. Emil Fischer B. Koshland
 C. Robin Williams D. Rudolph Virchow

Which statement is incorrect about Lock and Key Model?

Specific enzyme can transform only a Active site of an enzyme is a non flexible
A. B.
specific substrate structure.

Active site does not change before during It explains the mechanism of every
C. D.
or even after the reaction. chemical reaction.
  The rate of reaction is directly proportional to the concentration of an enzyme which statement
is incorrect in this respect:
Increase in enzyme molecule increases This relation is for unlimited time period
A. B.
the available active sites. with unlimited enzyme concentration

If the concentration is doubled the rate

C. D. None of these.
will become two fold.

If the concentration of enzyme is kept constant and amount of substrate is increased a point is
reached where increase in substrates concentration does not affect the reaction rate because of
Enzymes get denatured at higher substrate Rate of reaction is indirectly proportional to
A. B.
conc. substrate concentration at this point.

All the active sites on enzyme molecule are

C. D. None of these.
occupied.

If more substrate to already occurring enzymatic reaction is added more enzyme activity is seen
because:
There is probably more substrate present There is probably more enzayme available
A. B.
than there is enzyme. than there is substrate.

There is probably more product present The enzyme substrate complex is probably
C. D.
than there is either substrate or enzyme. failing to form during the reaction.

  If more substrate to already occurring enzymatic reaction is added and there is no effect on the
rate of the reaction what is the form given to this situation:
A. Saturation B. Denaturation

C. Composition D. Inhibition

The active site of an enzyme:

A. Never changes B. Forms no chemical bond with substrate

Determined by structure and the specificity

C. D. They are non specific in their action.
of the enzyme.

Excessive increase in temperature of medium causes the enzyme molecule to

A. Activate B. Unaffected
 C. Denatured D. None of these.
  Extreme change in pH results in:
Change in ionization of amino acids at the
A. B. Change in the ionization of the substrate.
active site of the enzyme.

C. Denaturation of the enzyme D. Increase in the reaction rate.

A chemical substance which can react (in place of substrate) with the enzyme but is not transformed
into product/s and thus blocks the active site temporarily or permanently is called
A. Co-enzyme B. Blocker

C. Inhibitor D. Cofactor
  Inhibitors which block the enzyme by forming weak bond are called
A. Competitive inhibitors. B. Non-competitive inhibitors

C. Irreversible inhibitors. D. Both a and b

A substance which binds at the active site of the enzyme but does not result in the formation of the
products is called:
A. Irreversible inhibitor B. Reversible inhibitor

C. Competitive inhibitor D. Non-competitive inhibitor

The structure of an enzyme is altered by:
A. Irreversible inhibitor B. Reversible inhibitor

C. Competitive inhibitor D. Non-competitive inhibitor

  Malonic acid is an example of:
A. Irreversible inhibitor B. Reversible inhibitor

C. Competitive inhibitor D. Non-competitive inhibitor

If enzyme concentration is low than substrate pH and temperature values are equal to requirement
then which of the following will increase rate of reaction.
A. increase in concentration of enzyme B. increase in concentration of substrate

C. increase in pH D. increase in temperature