A new study found that inducing senescence (cell aging) in aggressive breast cancer cells through a senescence inducer, and then selectively removing the senescent cells with a senolytic nanoparticle treatment, can both remove senescent cells and delay tumor growth as well as decrease metastasis. The combined therapy of first inducing senescence and then removing those cells with nanoparticles shows promise as a new therapeutic approach for treating aggressive breast cancer.
A new study found that inducing senescence (cell aging) in aggressive breast cancer cells through a senescence inducer, and then selectively removing the senescent cells with a senolytic nanoparticle treatment, can both remove senescent cells and delay tumor growth as well as decrease metastasis. The combined therapy of first inducing senescence and then removing those cells with nanoparticles shows promise as a new therapeutic approach for treating aggressive breast cancer.
A new study found that inducing senescence (cell aging) in aggressive breast cancer cells through a senescence inducer, and then selectively removing the senescent cells with a senolytic nanoparticle treatment, can both remove senescent cells and delay tumor growth as well as decrease metastasis. The combined therapy of first inducing senescence and then removing those cells with nanoparticles shows promise as a new therapeutic approach for treating aggressive breast cancer.
A new study led by the researchers Orzáez and Máñez found a therapeutic approach to treat aggressive breast cancer. In this model, senescence (cell aging) is induced in the cells through a senescence inducer and cells are selectively removed through a senolytic nanoparticle treatment. Thus, a combined therapy of senescence inducer and senolytic nanoparticle not only removes senescent cells but also delays the tumor growth and decrease metastasis. Metastasis involves many cells of the