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Senescence induction, a new treatment for

aggressive breast cancer


A new study led by the researchers Orzáez and Máñez
found a therapeutic approach to treat aggressive breast
cancer. In this model, senescence (cell aging) is induced in
the cells through a senescence inducer and cells are
selectively removed through a senolytic nanoparticle
treatment. Thus, a combined therapy of senescence
inducer and senolytic nanoparticle not only removes
senescent cells but also delays the tumor growth and
decrease metastasis. Metastasis involves many cells of the

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