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SPINE Volume 33, Number 16, pp 1800 –1805

©2008, Lippincott Williams & Wilkins

Physical Therapy for Acute Low Back Pain


Associations With Subsequent Healthcare Costs

Julie M. Fritz, PhD, PT, ATC,*† Joshua A. Cleland, PhD, DPT, FAAOMPT,‡
Matthew Speckman,§ Gerard P. Brennan, PhD, PT,* and Stephen J. Hunter, MS, PT, OCS*

The prevalence of low back pain (LBP) is at epidemic


Study Design. Case-control. proportions in the United States and elsewhere, affecting
Objective. To examine the association between adher- 60% to 80% of individuals during their lifetime.1 A sur-
ence to the evidence-based recommendation for active
physical therapy care and clinical outcomes along with
vey of residents of the United States found 26% of adults
subsequent healthcare utilization and charges for 1 year reported LBP lasting at least 1 day in the past 3 months.2
after completion of physical therapy. Considering the prevalence of LBP, it is not surprising
Summary of Background Data. Low back pain (LBP) is the condition imposes a significant economic burden on
a common condition associated with high costs. Many affected individuals, the healthcare delivery system, and
patients with acute LBP receive physical therapy. The type
of physical therapy care provided may impact subsequent society. Total annual direct healthcare costs in the
healthcare costs. United States incurred by patients with LBP were esti-
Methods. A retrospective review was undertaken of mated at 90 billion dollars in 1998, 60% higher than in
patients age 18 – 60 with acute (⬍90 days) LBP receiving individuals without LBP.3 Although costs for surgical
physical therapy covered by 1 insurance provider. Ad-
procedures are high, rates of surgery for patients with
herence to the recommendation for active care was
determined from billing records. Disability (Oswestry) LBP are low, and the majority of direct healthcare costs
and pain (numerical pain rating) were assessed at the are related to outpatient office-based services and pre-
beginning and completion of physical therapy. Subse- scription medication.3 Recent reports suggest that the
quent healthcare utilization for LBP and charges were use of physical therapy for patients with LBP is increas-
recorded from insurer’s databases.
ing.4,5 Although the proportion of direct healthcare costs
Results. Four hundred and seventy-one patients were
included (mean age 41.2 years [SD ⫽ 11.0], 54% female), for LBP attributable to physical therapy care has not
28.0% received adherent care. Patients receiving adherent been described in detail, the addition of physical therapy
care had fewer physical therapy visits (mean difference to primary care management can contribute substan-
1.3 visits, P ⬍ 0.05) with lower charges (nontrans- tially to direct healthcare costs for LBP.6
formed mean difference $167, P ⬍ 0.05), greater im-
Clinical practice guidelines are proposed to be an im-
provement in pain (mean difference 12.3%, 95% confi-
dence interval [CI]: 3.2–21.3) and disability (mean portant tool for maximizing clinical outcomes and con-
difference 17.6%, 95% CI: 11.1–24.1). During the year trolling healthcare costs for common conditions such as
after discharge, receiving adherent care was associated LBP.7 A few clinical practice guidelines have been devel-
with a lower likelihood of receiving prescription medi- oped explicitly for use by physical therapists for the man-
cation (46.2% vs. 57.2%, P ⬍ 0.05), magnetic resonance
agement of patients with LBP.8,9 These guidelines, as
imaging (MRI) (8.3% vs. 15.9%, P ⬍ 0.05), or epidural
injections (5.3% vs. 12.1%, P ⬍ 0.05). well as systematic reviews and practice guidelines devel-
Conclusion. Adherence to the recommendation for oped for primary care providers, are consistent in recom-
active care was associated with better clinical out- mending an active approach to care with emphasis on
comes and decreased subsequent use of prescription maintaining and promoting activity, while avoiding pas-
medication, MRI, and injections. Improving adherence
sive interventions such as bed rest or physical methods
to this recommendation may present an opportunity to
improve the cost-effectiveness of care for acute LBP. (heat/cold, ultrasound, etc.).10 –12 We previously exam-
Key words: low back pain, economic analysis, physical ined patients with acute LBP receiving physical therapy
therapy. Spine 2008;33:1800 –1805 and found that adherence to this recommendation for an
active approach was associated with better clinical out-
comes of physical therapy, with fewer visits and lower
charges for care.13 Although most individuals with an
From the *Rehabilitation Agency, Intermountain Healthcare, and acute episode of LBP experience rapid and pronounced
†Department of Physical Therapy, University of Utah, Salt Lake City, improvement, it is now understood that the natural his-
Utah; ‡Department of Physical Therapy, Franklin Pierce College, Con- tory of LBP includes subsequent periods of exacerbation
cord, New Hampshire; and §MS SelectHealth, Salt Lake City, Utah.
Acknowledgment date: November 13, 2007. Revision date: January and recurrence for most individuals.14 The healthcare
14, 2008. Acceptance date: February 25, 2008. resources consumed in attempts to manage the fluctuat-
The manuscript submitted does not contain information about medical ing and recurrent nature of LBP make it one of the most
device(s)/drug(s).
No funds were received in support of this work. No benefits in any expensive medical conditions in the United States.15–17
form have been or will be received from a commercial party related Examining the effectiveness of interventions occurring in
directly or indirectly to the subject of this manuscript. a period of acute symptom aggravation should therefore
Address correspondence and reprint requests to: Julie M. Fritz, PhD, PT,
ATC, 520 Wakara Way, Salt Lake City, UT 84108; E-mail: julie.fritz@ include both clinical improvement in the short term, and
hsc.utah.edu reductions in recurrences and associated costs in the long

1800
Physical Therapy for Acute LBP • Fritz et al 1801

term. The purpose of this study was to examine a cohort with other practice guidelines, this guideline advocated an ac-
of individuals with acute LBP receiving physical therapy. tive approach to management. The guideline was disseminated
We examined the association between adherence to the to physical therapists working at IHC, but no explicit training
evidence-based recommendation for an active approach was received, and therapists were not trained in the criteria for
adherence used in this analysis.
to physical therapy and short-term clinical outcomes and
subsequent healthcare utilization and charges accumu-
Short-term Clinical Outcomes of Physical Therapy
lated over a 1-year period after the completion of phys- During the episode of physical therapy care, clinical outcomes
ical therapy. were assessed using the OSW and pain rating. The OSW mea-
Materials and Methods sures disability related to LBP and has high levels of test-retest
reliability and responsiveness to change in patients with LBP.19
Subjects The numerical pain rating asks patients to rate their pain from
Data were collected from the clinical outcomes and financial 0 (no pain) to 10 (worst imaginable pain).20 Pain rating scales
databases maintained by the Rehabilitation Agency of Inter- have been shown to have concurrent and predictive validity as
mountain Healthcare (IHC), a private, nonprofit, integrated measures of pain intensity and responsiveness to change for
health care delivery system, and SelectHealth, a nonprofit patients with LBP.18 Pain rating and OSW scores were ex-
health insurance company that is an integrated subsidiary of tracted from the database for the initial and final physical ther-
IHC. The study was approved by the Institutional Review apy visit for each patient. Change scores were calculated by
Board of IHC. subtracting the final score from the initial score. Percentage
The study sample was identified from the clinical outcomes change was calculated as ((initial score-final score)/final score *
database maintained by the IHC Rehabilitation Agency. Pa- 100%).
tients receiving physical therapy in Rehabilitation Agency clin-
ics complete a condition-specific disability score and 0 –10 nu- Subsequent Health Care Utilization and Charges
merical pain18 rating at each visit, and the scores are entered Records from the clinical outcomes database of included pa-
into the clinical outcomes database. The database also includes tients were linked to financial databases using the enterprise
the patient’s age, duration of current symptoms, and dates of master patient index number. Charges for the episode of phys-
service. For patients with a chief complaint of LBP, the condi- ical therapy care were recorded. Additional charges billed to
tion-specific disability scale is the Modified Oswestry Disability the patient’s insurance related to the management of LBP were
Questionnaire (OSW).19 collected for a 1-year period from the conclusion of the episode
Patients included in this analysis were those entered into the of physical therapy care. We identified charges related to LBP
clinical outcomes database that had an episode of care for LBP as those that were associated with 1 of the following Interna-
at 1 of 10 outpatient physical therapy clinics between January tional Classification of Diseases codes: 719.45, 719.55, 721.3,
1, 2003, and December 31, 2005. Patients receiving treatment 722.1, 722.2, 722.52–722.93, 724.0, 724.02, 724.2, 724.3–
for LBP were identified as those for whom the OSW was en- 724.9, 737.3, 739.4, 756.11, 756.12, 846.0 – 846.3, 846.8,
tered as the disability scale. An episode of care was defined as 846.9, 847.2, 847.3. Charges represented standard billed
time from the date of the initial evaluation to the last visit. If no charges and were collected for prescription medication, office
visits occurred for more than 45 days, the episode of care was or emergency room visits, inpatient/surgical services, and diag-
considered complete. Patients were included if the insurance nostic procedures. Charges from 2003–2005 were adjusted by
provider for the episode of care was SelectHealth. Further in- 4% annually to reflect inflation of medical costs.
clusion criteria for the analysis were; age 18 – 60 years, dura-
tion of symptoms ⬍90 days, at least 3 physical therapy visits, Data Analysis
duration of physical therapy at least 10 days, initial OSW score Baseline characteristics at the beginning of the physical therapy
⬎10%, and no surgery date recorded. episode of care were compared between patients receiving
Adherence of Physical Therapy Care guideline-adherent versus nonadherent care using indepen-
We determined adherence to the recommendation for an active dent-group t tests or appropriate nonparametric alternatives.
approach during physical therapy using methods described in We also compared the number of visits and duration of the
detail elsewhere.13 Briefly, we divided the episode of care was physical therapy episode of care using nonparametric Mann-
divided into phase I (first 2 weeks), and phase II (2 weeks and Whitney U tests because of the skewed distribution of these
beyond). Adherence was determined by examining the current variables. An ␣-level of P ⬍ 0.05 was used for all comparisons.
procedural terminology codes billed for visits within each We used linear mixed model analyses to examine the rela-
phase. Codes were categorized as active (exercise and therapeu- tionship between guideline adherence and clinical outcomes of
tic activities consistent with guideline recommendation), pas- the physical therapy episode of care controlling for symptom
sive (heat/cold methods, electrical stimulation, ultrasound, etc. duration, age, sex, year of admission, and baseline pain and
that are inconsistent with recommendations), or allowed (eval- disability. The mixed model was used to account for the poten-
uation, equipment, etc. unrelated to recommendations). The tial correlation among patients nested within physical therapy
ratio of active:passive codes had to be at least 3:1 for each clinics. Separate analyses were performed using percentage
phase, and every visit had to have at least 1 active code for the change in pain and disability as dependent variables. We also
patient’s care to be considered adherent to guideline recom- compared the proportion of patients achieving a successful outcome
mendations. in each group using a Pearson ␹2 test. Consistent with previous
studies,21,22 a successful outcome was defined as achieving at
Physical Therapist Training least 50% improvement on the OSW-disability score. Charges
A clinical practice guideline for primary care management of for the physical therapy episode of care between groups were
patients with LBP was developed at IHC in 2004. Consistent compared using linear mixed model with the covariates de-
1802 Spine • Volume 33 • Number 16 • 2008

Table 1. Descriptive Characteristics of Study Subjects


All Subjects (n ⫽ 471) Adherent (n ⫽ 132) Nonadherent (n ⫽ 339)

Age 41.2 (11.0) 40.3 (11.0) 41.5 (11.0)


Sex (% female) 53.9 53.0 54.3
Symptom duration (d) 31.0 (25.0) median ⫽ 24 33.9 (24.4)*† median ⫽ 30 30.0 (25.2)*† median ⫽ 21
Initial Oswestry score 39.4 (14.6) 36.1 (13.3)† 40.7 (15.0)†
Initial pain rating 5.5 (2.3) 4.7 (2.3)† 5.8 (2.2)†
*Mann-Whitney U test.
†P ⬍ 0.05 for comparison of adherent and nonadherent groups.

scribed above. Charge data underwent square root transforma- herent care. Patients receiving adherent care experienced
tion before analysis to reduce positive skewness. greater improvement in disability (mean difference in
Evaluation of the association between receiving adherent percentage change on the Oswestry score ⫽ 16.2%, 95%
care in physical therapy and subsequent healthcare utilization
CI: 9.5–22.9), and pain intensity (mean difference in per-
began with ␹2 comparisons of utilization rates. We compared
the proportion of patients in each group who received prescrip-
centage change on the pain rating ⫽ 11.3%, 95% CI:
tion medication (nonsteroidal anti-inflammatories, opioid an- 1.6 –20.9), and were more likely to experience a success-
algesics, skeletal muscle relaxants, or corticosteroids), addi- ful physical therapy outcome (59.1% vs. 37.8%, P ⬍
tional physician visits (e.g., family practice physical medicine, 0.05) than patients receiving nonadherent care (Table 2).
orthopedic surgery, etc.), visits to an emergency room or urgent Patients receiving adherent care also attended fewer
care facility, diagnostic imaging procedures (e.g., radiographs, physical therapy visits, had a shorter length of stay, and
magnetic resonance imaging [MRI], etc.), additional rehabili- lower charges for physical therapy care (Table 2).
tation visits (physical therapy or chiropractic), injection, or Overall, 296 patients (62.8%) had billed charges for
surgical procedures for the management of LBP in the 1-year
additional healthcare related to the management of LBP
period after completion of the physical therapy episode of care.
When significant univariate associations were identified, we
in the 1-year period after completion of the physical ther-
also constructed multivariate logistic regression models to apy episode of care. Among patients receiving adherent
examine the association between adherent physical therapy care in physical therapy, the rate of additional healthcare
care and subsequent healthcare utilization adjusting for age, utilization was 55.3% compared with 65.8% among pa-
sex, and duration of symptoms. Adjusted odds ratios (OR) tients receiving nonadherent physical therapy (P ⬍ 0.05).
with 95% confidence intervals (CI) were computed. We com- Associations between adherent care in physical therapy
pared mean charges for subsequent healthcare utilization be- and subsequent utilization of specific types of care are
tween groups using linear mixed model procedures with the provided in Table 3. Receiving adherent care was asso-
data transformation and covariates described previously. We
ciated with a decreased use of prescription medication
examined the association between incurring high charges and
adherent physical therapy care. Patients with high charges were (adjusted OR ⫽ 0.64, 95% CI: 0.43– 0.97, P ⬍ 0.05).
defined as those in the 75th percentile of the distribution of Among the most common prescription medications, re-
adjusted subsequent healthcare charges. Adjusted OR values ceiving adherent care was particularly associated with a
were calculated as previously described. decreased use of muscle relaxants (adjusted OR ⫽ 0.59,
95% CI: 0.35– 0.99, P ⬍ 0.05). Adherent care was also
Results
associated with a decreased likelihood of receiving diag-
During the time period of the study, 471 patients with nostic imaging procedures (adjusted OR ⫽ 0.53, 95%
LBP met the criteria for inclusion. Descriptive data for CI: 0.31– 0.92, P ⬍ 0.05). In particular, adherent care
these patients is contained in Table 1. Using the defini- was associated with decreased use of MRI (adjusted
tion for adherence to the recommendation for an active OR ⫽ 0.47, 95% CI: 0.24 – 0.94, P ⬍ 0.05). The use of
approach described previously, 132 patients (28.0%) re- injection procedures was also less likely among patients
ceived adherent care and 339 (72.0%) received nonad- receiving adherent care (adjusted OR ⫽ 0.40, 95% CI:

Table 2. Clinical and Financial Outcomes From the Episode of Care in Physical Therapy
All Subjects (n ⫽ 471) Adherent (n ⫽ 132) Nonadherent (n ⫽ 339)

No. physical therapy visits 5.5 (2.5) 4.6 (2.0)*† 5.9 (2.2)*†
Duration of physical therapy care (d) 28.5 (19.5) median ⫽ 22 25.4 (16.2)*† median ⫽ 19 29.7 (20.6)*† median ⫽ 22
Physical therapy charges $683 (334) $562 (269)† $729 (345)†
Percent change in Oswestry 42.0% (34.0) 53.7% (33.1)† 37.5% (33.3)†
Percent change in pain rating 41.9% (46.7) 49.1% (45.9)† 39.2% (46.8)†
Successful outcome of physical therapy (n %) 43.7% 59.1%† 37.8%†
Numbers represent mean (standard deviation) unless otherwise indicated.
*Mann-Whitney U test.
†P ⬍ 0.05 for comparison of adherent and nonadherent groups.
Physical Therapy for Acute LBP • Fritz et al 1803

Table 3. Utilization of Additional Healthcare Services in the Year After the Episode of Physical Therapy Care
All Subjects (n ⫽ 471) Adherent (n ⫽ 132) Nonadherent (n ⫽ 339) Adjusted OR (95% CI)

Prescription medication 54.1 46.2* 57.2* 0.64 (0.43, 0.97)


Opioid analgesics 35.9 30.3 38.1
Nonsteroidal anti-inflammatories 35.5 32.6 36.6
Skeletal muscle relaxants 22.9 16.7* 25.4* 0.59 (0.35, 0.99)
Systemic corticosteroids 11.0 9.1 11.8
Physician office visits 24.0 19.5 25.7
Physical medicine 19.1 15.9 20.4
Family practice 12.7 9.1 14.2
Orthopedic surgery 7.4 6.8 7.7
Internal medicine 4.0 3.8 4.1
Neurosurgery 3.0 1.5 3.5
Emergency/urgent care visits 2.8 1.5 3.2
Diagnostic procedures 21.0 14.4* 23.6* 0.53 (0.31, 0.92)
MRI 13.8 8.3* 15.9* 0.47 (0.24, 0.94)
Spine radiographs 9.8 6.8 10.9
Nerve conduction/EMG 1.7 2.5 1.3
Computed tomography scan 1.4 0 2.1
Surgical procedures 3.2 3.8 3.0
Surgical procedure without fusion 2.3 2.3 2.4
(discectomy, etc.)
Surgical procedure with fusion 0.8 1.5 0.6
Injection procedures 13.2 9.1* 15.9* 0.40 (0.18, 0.85)
Epidural injection with fluoroscopy 10.2 5.3* 12.1* 0.40 (0.18, 0.94)
Injection without fluoroscopy 4.2 3.0 4.7
(intramuscular, trigger point, etc.)
Rehabilitation visits 9.3 9.1 9.4
Additional physical therapy 8.3 9.1 8.0
Chiropractic 1.1 0 1.5
All values are indicated in percentages, unless otherwise indicated.
OR adjusted for age, sex, and duration of symptoms are provided for services differing significantly between groups.
*P ⬍ 0.05 for comparison of adherent and nonadherent groups.

0.18 – 0.85, P ⬍ 0.05), in particular the use of fluoro- apy,4,5 Similar to other healthcare providers, it appears
scopically-guided procedures (adjusted OR ⫽ 0.40, 95% that physical therapy care for patients with LBP is char-
CI: 0.18 – 0.94, P ⬍ 0.05). acterized by widespread and unwarranted variations in
Differences in mean charges for subsequent healthcare practice.29 –31 Practice variation is believed to contribute
costs between patients receiving adherent or nonadher- to increased costs and suboptimal clinical outcomes.
ent care in physical therapy did not reach statistical sig- Consistent adherence to evidence-based guidelines is ad-
nificance. Mean charges were $1692 (SD ⫽ $7683) for vocated as an important and necessary step for improv-
patients receiving adherent care, and $2829 (SD ⫽ ing the cost-effectiveness of care for individuals with
$21,728) for patients receiving nonadherent care (P ⬎ LBP.32,33 Our previous work found an association be-
0.05). Receiving adherent physical therapy care was as- tween improved short-term clinical outcomes and phys-
sociated with a reduced likelihood of incurring high ical therapy care that was adherent to the recommenda-
charges for subsequent healthcare (adjusted OR ⫽ 0.51, tion for an active approach.13 This study extends the
95% CI: 0.31– 0.87). Mean overall charges for care previous findings by examining the association of adher-
(charges for physical therapy ⫹ charges for subsequent ence to this evidence-based recommendation with
healthcare) were $2255 (SD ⫽ $7665) for patients re- healthcare utilization in the longer term.
ceiving adherent care and $3559 (SD ⫽ $21,720) for This study used a retrospective case-control design to
patients receiving nonadherent care (P ⬎ 0.05). Receiv- examine the association between the management pro-
ing adherent physical therapy care was associated with a vided in physical therapy and short-term clinical im-
reduced likelihood of incurring high overall charges (ad- provement and longer term reductions in the utilization
justed OR ⫽ 0.44, 95% CI: 0.26 – 0.75). of, and charges for additional healthcare services. Al-
though this design is unable to provide causal evidence,
Discussion
the results found significant associations between the
Recognition of the substantial economic burden of LBP physical therapy care received during the acute phase
has increased scrutiny on how healthcare resources are and greater short-term clinical improvements and reduc-
used for the condition. Wide variations in clinical care tions in subsequent use of various healthcare resources.
have been documented in rates of surgery, prescribing of Patients whose physical therapy care was adherent to the
medications, use of imaging, and specialist referrals for evidence-based recommendation to focus on active inter-
patients with LBP.23–28 Many patients experiencing an ventions instead of passive methods were less likely to
acute exacerbation of LBP are referred to physical ther- receive prescription medication, diagnostic, or injection
1804 Spine • Volume 33 • Number 16 • 2008

procedures in the 1-year period after the physical therapy lated to out-of-pocket expenses and missed time at
episode of care than those patients whose care was non- work.42 We were unable to account for these costs in our
adherent to this recommendation. Although alternative analysis.
explanations should be considered, these results suggest
an opportunity for more cost-effective care if an active
Conclusion
approach in physical therapy was used on a more con-
sistent basis. This study found that adherence to the evidence-based
The recommendation for an active approach to care recommendation for an active approach to physical ther-
for patients with acute LBP has been supported by sev- apy care for patients with acute LBP was associated with
eral randomized clinical trials and is included in almost better clinical outcomes for the episode of physical ther-
all clinical practice guidelines for physicians or physical apy and decreased use of prescription medication, MRI,
therapists.9,10,34,35 Given these consistent recommenda- and epidural steroid injections in the year after dis-
tions, it may be surprising that adherence to an active charge. Improving adherence to this recommendation in
approach has been reported to be low in studies of both physical therapy may have important implications for
primary care physicians and physical therapists.13,32,36 improving outcomes and reducing subsequent health-
Lack of adherence to evidence-based recommendations, care costs for individuals with LBP. Further research is
however, has proven a challenge for clinicians and needed to explore the impact of initial management
healthcare systems in nearly every clinical condition that strategies on subsequent healthcare costs for patients
has been studied.37 Research on methods to improve with acute LBP.
adherence has yet to identify consistently effective strat-
egies for changing the behavior of clinicians.37 Given the
cost implications, many health plans are moving towards Key Points
greater alignment of reimbursement with provision of ● Physical therapy care provided to patients with
care that adheres to evidence-based guidelines.38 Evi- acute low back pain was not consistently adherent
dence on the impact of pay-for-performance programs to the evidence-based guideline recommendation
on clinician behavior and clinical outcomes is beginning to provide active, as opposed to passive care.
to emerge, but the effectiveness of these programs is cur- ● The provision of physical therapy that was ad-
rently uncertain.39,40 herent to the guideline recommendation for active
The ability to effectively alter the natural history of care was associated with better clinical outcomes
LBP during the acute phase has not be effectively dem- for the physical therapy episode of care.
onstrated, and therefore most primary care practice ● The provision of physical therapy that was ad-
guidelines and expert recommendations suggest a period herent to the guideline recommendation for active
of “watchful waiting” without referral during the initial care was associated with lower utilization of pre-
weeks of an acute episode of LBP.41 We were not able to scription medication, imaging, and injection proce-
examine a group of patients with acute LBP who did not dures.
receive any physical therapy. Therefore, we cannot ad- ● For patients with acute low back pain, the type of
dress the cost-effectiveness of a watchful waiting ap- care provided during the initial management may
proach instead of referral to physical therapy during the have implications for subsequent health care utili-
initial weeks of symptoms. The results of this study, zation and costs.
however, suggest the potential financial impact of the
management strategies used during the acute phase of an
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