Studies have found that Tibetan populations living at high altitudes, such as the Mosuo people, have a lower risk of hypertension and diabetes-related anemia compared to low-altitude populations. Researchers believe this is due to genetic adaptations that help high-altitude populations cope with low oxygen levels, such as increased blood flow and altered red blood cell production. A recent study comparing the Mosuo and Han Chinese populations supported the hypothesis that high-altitude adaptations can reduce the risk of certain chronic diseases.
Studies have found that Tibetan populations living at high altitudes, such as the Mosuo people, have a lower risk of hypertension and diabetes-related anemia compared to low-altitude populations. Researchers believe this is due to genetic adaptations that help high-altitude populations cope with low oxygen levels, such as increased blood flow and altered red blood cell production. A recent study comparing the Mosuo and Han Chinese populations supported the hypothesis that high-altitude adaptations can reduce the risk of certain chronic diseases.
Studies have found that Tibetan populations living at high altitudes, such as the Mosuo people, have a lower risk of hypertension and diabetes-related anemia compared to low-altitude populations. Researchers believe this is due to genetic adaptations that help high-altitude populations cope with low oxygen levels, such as increased blood flow and altered red blood cell production. A recent study comparing the Mosuo and Han Chinese populations supported the hypothesis that high-altitude adaptations can reduce the risk of certain chronic diseases.
Have you ever that the mountains could lower your risk for certain long term ailments?
Studies have found that a Tibetian descended population,
the Mosuo, possess lower risk for hypertension and diabetes associated anemia than low altitude Han population.
“During the last decade, the knowledge regarding high
altitude adaptations in humans has increased tremendously and this flood of knowledge led us to question how chronic disease incidence is influenced by these adaptations. Our research indicates that Himalayan adaptations to high altitudes have additional effects beyond helping people cope with low availability of oxygen; they also tend to reduce the risk of hypertension and anemia among diabetics” said a researcher from Binghamton University.
The hypothesis that was formulated stated that these
adaptations could also affect the chronic disease pathways for conditions like hypertension and diabetes. Human populations that are adapted to Himalyan high altitudes have higher blood flow due to dilatation of blood vessels which may increase oxygen supply even in poor blood oxygen concentrations and these dilatation could be the reason for lowered risk of hypertension.
Besides this, these Himalayan populations have also lost
the mechanism that usually increases the output of red blood cells in response to low blood oxygen which protects them against high viscosity blood and this probably could be the other mechanism reducing risk of diabetes associated anemia.
The study comparing Mosuo and Han population
supported these hypotheses. Mosuo risk for hypertension was much lower than Han population.
“While globalization continues to influence the
populations of the planet, the epidemiologic and nutritional conditions of people are shifting. In most instances it leads to an increased risk of diabetes and hypertension” says one of the researchers from the University of New Mexico. “some of this is happening in Mosuo case- high incidence of diabetes but study showed unique adaptations leading to different health states.”
The research suggests that as these chronic diseases are
becoming a major health concern, it is important to investigate how risk is related to genetic adaptations in local environment.
“As diseases like obesity are increasing day by day on a
global level, it becomes a prime concern to understand how the human populations are interacting with the physilogy of these problems” quoted one of the researchers.
The collection of data for the above mentioned study
involved visits to household, questioning people about their lifestyle and obtaining health information from blood samples.