You are on page 1of 6
Pynoo J aeys ony Apos9A98 uewyney, ag 4s: “soos: UL yom MAIAIIU OIpEL B76] e 993 at BuLA!9994 54 au>pau 4 |N99) Oe] sea AUAIS s0K0 mtu Ho 328}. [woyauaq Su puE (oprureUroUIN) fq UIWEDIA Supresos ueuyneyy 2d J0 sSupua pur sotissoosip ayn sozzzeununs ioideys sy. ‘stusned 20H 07 Pouiddey sey aeyss woos sey oym sueraisayd Aq pu kpmas pajjon ouo £4 Pattayuo> uodq sey 3 YBnowp UaAD “Lou seat 3] “AjsnoL49s Kron ‘roncosip qevodur siys sey) yYurp pinom up, 34819 waAD 40 sno Oxu papialp ‘Kep sod (Bu) sures 000° aseaj ae pasn apy ‘Bure jo sofuey> ayp Jo Auvu pur aplureurseru jo sosop a8ze) sey po, ‘saffo apis assoape ou posnvo seq asn Jo Sepak wuoned pursnod v us (sunurta sous0 quer PeHiqIu02 40 auoyP) aprupiasrin soqa porou 1 4d “CW ‘ueuyney WIM $0 20M Bus9U0Lg ayy “OpHWEWIIEN YUM SHUWY Buissanay 2 YaLdVHD aay Ajpemoe sey) seamsopun jpe-s1y-s718-9u0 wfSnog nod ours asy] ays st uayAR éSP20U jeuoRIMU ous aya YoNUL A4x94d e24 [9a og Zam tumLULUTLY 103 320m aUOKI9K9 PINOYS “papaoaxa 94 tonou Kew aeys afeas wnumurus parepuew e sajquiasas 31 Mo} a “ae, ays Srensuowap syCTY se Pury “eA9AE jeanal0aYA F uo pasey wwatH Irontjod © stay soysey “uossad ayzoods Kuv 02 éjddv Ajjeas rou saop nA UDAid v (Var) aeuemoy Asex91q papuoun ‘adueyp spurwop USI |eIOYYO sy], “Io poruowojddnsun od B Woay poureago aq ue> poou Kou] Uo up ype awyp anuju0s 4 ‘Poured, Al0S 34 SLL :NIDVIN 08 Joey iq] suyesu09 ,e1eq JENN Jo sISSIeUY, BBeU-Zp UL =F MAdEIED rusSrurus 9409 20) nyc Jo Aseumuns Jorg w st ,guouBe3J], Jo wore “ayayane 20g Sdesoyp uuneyseou vu aeys ssorse} 19420 pur hed pus easy Syeoytoods on) apyuseuse sty udsoad uewyMey C1 ep sDiieYD ny} WeUynerywosypsunoLu0.0p-mMAy poskod ose axe soouasojer g}-7 $4009 341, Ul|Uo a{qupRAE MOU St HOM “sxogr pauotua Se pure ‘Mojaq suatuos 2xp yo AzetLUNS 1084 Yoo auenodia ,ueuyney 3 uouounjske vasof Jo Muto, woo’ aq], JO MO1A194G Jonge “édeaoya apr pen avenbape yo woreanp 24) wo 498s spuadp L1u9498 Jo axp ‘uaaf# Aue Jo wonsunysip auto! woxy AsaKoD03 yo 200Ix9 amp “eI je a3 Jo stypsvou Quou9xou au 0 sous ut swoussosdan a}qemeeous oun ut st a3 “sprueueU Jo suNOWE xenbopr pm tap 391] 30 poo 3 ousayddnsstossad yons “oe Suteasour ate 339895 poo lupe stosiad sie ey eps paseasvowp Hay sy _soveas ‘wouro4y, pu s>uaprouy sa wonounfiy mo Jo macy wonanery 241, 3004 REIN “Avp 20d sos0p uay o1u popralp ‘Sup sod Bu og" o feo ¥ 02 da popoot suaped sauyue pads si2495 -s9s0p ays avonbouy axow oyp “sou ayy sonos8 ou, ued pur ured yiog 219K cep Bunge axp snoysoo.yp Jo spx3] poo}g 242 224 05 *S9SOp oqp apuatp or K4vssaou st a] suugue ur syns 2]qusoaey Ajjeas Aue 298 pue asop A834] 3j8uys © an y0uue> 240 “sauypre yo s9019op Burks pia suoned Jo asuodsa1 92 ‘Huan Ajjemoe hg ajnpoyos (afesop fq wurenaeow) Sus ae poause fy “ue syns 219m sso! 1 :20}94 sem 94 asoya. PEG Sem ay yoDH © UI “(oga>e|A) BUIIPaUE aE Joo] © wy 2408 pue aro UY % 8 ty puog pyno> ay wows pur OP paplnyp ut 99m 30j apHUEHIDE La ae | ua 30 ‘uo se 9} “aznssoud pooyg sly ainseaw 0 Ylnous sinoqp> 4 pdg 200 Dr. William Kaufman's Notes ‘on Niacinamide Therapy for Arthritis! (Used wth the kind permlsion of Charlotte Kaufman) The more equent 250 mg dose ofriacnamide i 40 to 0 percent more ectven he 1955 papein the Jura of the American Gerais Soci, pated hat ia combined with other vitamins na thousand patient-years of se has tay nin ies tha aca pet Naina has ungated entrance tothe cental enous stem. thas astrongafn- iy forthe ental nervous systems benzodiazepine receptors and causes pleasant mative fet nation it improves central nenes stem function inthe hn of central neausyptom ipairments ted in my 183 book, tating on page. me!” She was so much better that! beg: surgery, some Fane Je had been admited that some 70,000 deaths, largely from ca vascular episodes, had heen associated with d se Such exe side effects had been known by the industry for several year. In Feb: Administration voted risk, so long as they aso carry a black-box warning. Given the evi dence thae arthritis ean often be succesflly treated with mi ‘othae nutrients, these decisions raise many interesting ethic oxx as it applies to TT Whatisier Viana Dry cures \e No ives pain? Yes Yes Negative side effects? ir, not Majo Positive side eects? Many None Toxie ‘ No ts ‘ouses deaths? No any cost heap pene Patented? No ts 66%) among, 1,075 placebo ps 18 minimized the appearance of any mo ot review and revealed that there was no data and ard forthe protocol 078 study. Theft ‘ease study suggest that additional protect NIACIN: The Real Story Ross et al. (2008) present'a case-study review of industry documents that demonstrates that clinical trial manuscripts related to rofecoxib were authored by sponsor employees, but they often attributed first author- ship to academically affiliated investigators who did not always disclose industry financial support. Review manuscripts were often prepared by unacknowledged authors and subsequently attributed authorship to aca- demically affiliated investigators, who often did not disclose industry financial support.? (For more on this topic, see Hill, et al., “The ADVAN- TAGE Seeding Trial” in the For Further Reading section of this book.) Based on these two reports, an article by DeAngelis and Fonanarosa concluded: “The profession of medicine, in every aspect—

You might also like