Bioreactor - Probes

Probe Belt
Probes on head plate

Probes
 Bioreactor – Cooling Jacket

• Cells give off heat when growing and dividing.

• To maintain a constant temperature in the reactor, the vessel
is covered by a cooling jacket.
• Coolant (cold water or glycol) flows through the cooling jacket
to regulate the temperature.
• The temperature is controlled by the flow rate of the coolant.
 Bioreactor – Cooling Jacket

Stainless Steel Cooling Jacket

surrounds the vessel.
 Bioreactor - Ports

• Bioreactors require addition ports, where material is either

introduced or removed from the vessel.
• Ports are needed to add the media (media port), cells
(inoculation port), and nutrients (feed ports).
• Ports are also used for the addition of acid and base for pH
control.
• A sample port is also located on each vessel to remove
culture for off-line investigation.