Additives for

PERSONAL CARE &

HOME CARE

Working for a sustainable life

 introduction of Chemipol

Chemipol is a chemical company established in 1979, manufacturer and supplier of a wide range of biocides,
additives and process chemicals.
We provide innovative technologies, highly effective products and expert support services through specialized technical sales
groups with outstanding expertise in customer point of view.

Head office, production and laboratories: Spain (near Barcelona)

Commercial offices:
Egypt (El Cairo) – Middle East
China (Shanghai) – China
Mexico (Queretaro) – Mexico

Distribution network with distributors in more than

70 countries.
 introduction of Chemipol

Chemipol supplies preservatives, formulation additives and process additives to the following sectors:

Agrochemicals Emulsions and adhesives

Oil and fuel Detergency

Metalworking Coatings

Paper Cosmetics and Personal Care

Desalinization Treatment of cooling towers

Wastewater treatment Potabilization

 preservative testing
EFECTIVENESS:
Minimal Inhibitori Concentration

CHALLENGE TEST

Inoculum:
UNE 11930 STANDARD (1 Million of microorganism for each sample tested)
gram +(S. aureus), gram – (E. coli and P. aeuroginosa), fungi (A.niger) and yeast (C. albicans).
CCT (COSMETIC CHALENGE TEST) (Between 10-20 Million of microorganism on each sample tested)
A mixture culture of gram + (S. aureus), gram – (E. coli and P. aeuroginosa), fungi (A.niger) and
yeasts (C. albicans).
Incubation:
UNE 11930 STANDARD
Individual incubation and counting.
CCT
Mixture incubation and counting (more actual)
Count:
UNE 11930 Readings after 7, 14 and 28 days, independent count
CCT Strike after 7 days for each 4 inoculation, pool count
 Preservative testing

CHALLENGE TEST
Result assessment CCT

Result assessment based on UNE 11930 criteria of acceptance.

Microbial reduction relative to the accumulated inoculum (log N0 – log Nx).
The antimicrobial efficacy is considered successful when the results show the following criteria:
- Bacteria require a 3 log reduction at the end of 4 cycle of inoculation.
- Mould & Yeast 1 log reduction at the end of 4 cycle of inoculation.
- Accepted deviation of 0,5 log. Possible increasing between cycles caused by the new inoculation

Bacteria
-- Heavy growth (x > 106) No Log red
- Moderate growth (106 > x > 104) < 2,5 Log red
+ Well preserved (UNE&Pharma method)(104 > x > 103) > 2,5 Log red
++ Optimum value (CCT chemipol test) (x < 103) > 3 Log red

Fungi & Yeast

-- Heavy growth (x >105) No Log red
- Moderate growth (>105 > x > 5x104) < 0,5 Log red
+ Well preserved (UNE&Pharma method) (5x104 > x > 1x104) > 0,5 Log red
++ Optimum value (CCT chemipol test) (x < 104) > 1 Log red
 Household active ingredients preservation

Properties of the heterocyclic compounds

ACTIVES CMIT/MIT BIT BIT/MIT
247-500-7 220-120-9
CE Number 220-120-9
220-239-6 220-239-6
2634-33-5
CAS Number 55965-84-9 2634-33-55
2682-20-4
Efficacy High Low Medium
Activity - Spectra Very wide Pseudomonas Very wide
pH stability 3.0 – 9.0 3.0 – 13.0 3.0 – 10.0
Thermal stability 55 – 60 °C 80 °C 80 °C
Reactions Reducing agents Oxidizing agents Stable
Use General Softeners pH 10 / softeners
Preservation cost x1 x8 x4
Labelling EUH208/H 317 1,5 / 15 ppm 50 / 500 ppm 100 / 1000 ppm
 active ingredients

Minimal inhibitory concentration ( ppm ) Preservative CMIT/MIT MIT/BIT BIT observation

CMIT/MIT MIT/BIT
Microorganisms Type BIT 0,1% BIOPOL WJ 15 OK
3:1 1:1
Pseudomonas aeruginosa gram - 5 20 250 0,2% BIOPOL XM 100 OK

Pseudomonas fluorescens gram - 2 15 100 0,1% BIOPOL VR 20 200 not enough

Escherichia coli gram - 8 10 100

Microbiolgical activity of heterocyclic compounds

Proteus vulgaris gram - 4 10 100
250
240

Staphilococcus aureus gram + 5 30 100 230

220
CMIT/MIT

210 MIT/BIT
200
BIT
190
180
Bacillus subtilus gram + 2 40 20 170
160

c.m.i (ppm)
150
140
130

Aspergillus niger Hongo 5 50 200 120

110
100
90
80
70
Penicillium funiculosum Hongo 1 50 100 60
50
40
30
20
10
0
Pseudomonas aeruginosa Pseudomonas fluorescens Escherichia colI Porteus vulgaris Staphylococcus aureus Bacillus subtilus Aspergillus niger Penicillium funiculosum

Organismes
¿ Why use CMIT/MIT?
SOLUBILITY
His very low log pow guarantee the perfect
homogenization in water based products ,
improving the contact with the microorganism,
minimizing the contact time with the bacteria
and improving the cellular death .
CMIT
MIT
TOXICITY & BIODEGRADABILITY
Sensitizing product at 15 ppm of active
ingredient (2-3 times the m.i.c. worst case).
Free CMR preservative solution.
Environment reduced impact
WIDE ACTIVITY SPECTRA
Multidiane ingredient , active against
bacteries , moulds, yeast and algae by it´s
method of action that affect the krebs cycle
that all of microorganism have some part in
his metabolism functions.
COMPATIBILITY
Excellent compatibility with detergents and
cosmetics raw materials .Possible to use
combined with other actives
CMIT/MIT ® Unique mechanism of action

CMIT/MIT is an active with a unique method of action based in a enzymatic disruption attack
that improve inhibition of respiration ,ATP generation and the assimilation growing.
The disruption of the cellular metabolism and the accumulation of damage beyond the capacity
of the cell to repair results in cell death , this disruption action combined with electrophilic direct
attack , secondary electrophile generation and an intracellular generation of free radicals
stresses the cell´s natural radical defense mechanism .

KREBS CYCLE NUTRITIONAL ATP

*Alpha- METABOLISM GENERATION
Ketoglutarate * Lactate * NADH
* Pyruvate Dehydrogenase Dehydrogenase
* Succinate
Dehydrogenase
 active ingredients
Advantages of the blends of actives ingredients

Better response to massive contaminations that can happen with reused water.

Effectivity enhancement: they combine short term disinfection with long term preservation.

Improve and complement the activity spectra, capacity for vapour phase protection.

Improve the stability of the heterocyclic compounds, reducing labelling requirements and costs.
Products offered by CHEMIPOL
Free formaldehyde actives Formaldehyde releasers / donors
PRODUCTS Heterocyclic compounds O-formal N-formal C-methylol
CMIT/MIT BIT MIT/BIT EGHF TMAD BNPD
BIOPOL WJ X
BIOPOL JM X X
BIOPOL MSO X X
BIOPOL IB X X
BIOPOL VR X
BIOPOL XM X
BIOPOL XMT X X
BIOPOL XMB X X
SANIPOL 103 Disinfectant of specific action based on DBNPA
 preservation in cosmetics

Products we supply to the cosmetic industry:

Chemipol supplies preservative agents for leave-on and rinse-off products of Personal Care and cosmetic
formulations. Our portfolio of preservatives covers a wide range of antibacterial active substances for classical and
more innovative formulations for the control of bacterial, molds and yeasts development in cosmetic products.

Preservatives

Organized in two wide range of products and solutions for the protection for leave-on and rinse-off cosmetic
products as innovative and classic formulations.

SENSICARE® C BIOPOL®
Low toxicity preservatives, innovative Preservatives based on classic active
solutions, based on the innovative substances.
use of existing active substances for
preservation of cosmetic products.
Chemipol’s classic preservation systems

CATEGORY
Product Face Shaving Body Sun Hair Decorative Wet
Face care Body care Hair care Hair styling
cleansing products cleansing protection cleansing cosmetics wipes

BIOPOL C 20




BIOPOL C 30




BIOPOL MI 10




BIOPOL DHN 










BIOPOL DHI



BIOPOL DHK  
 






BIOPOL DHP






BIOPOL PB 6







BIOPOL PB 17








especially recommended  recommended
possible
Plant hygiene

Hygiene plant products

Chemipol have under the brand SANIPOL® a family of a full range of products or the plant hygiene
including cleansing products for the production facilities and sanitizing solutions for the cleaning of
cosmetic facilities. BIOCHECK® is an analysis kit for the microbiological checking of products and raw
materials.

SANIPOL® BIOCHEK®
Formulations based on different biocidal active Dip slides for microbiological control, quick and simple. It is
substances, surfactants and dispersing agents. recommended for the verification of the correct state of the
raw materials, end product and facilities.

Benefits Benefits

Cleansing Easy to use

Disinfection Minimize the necessities of a microbiological laboratory
Elimination of solids and fatty residues. Control of bacteria and fungi with the same test
 innovative preservation systems

SENSICARE ® is an innovative range of preservatives for protection of all type of leave-on and rinse-off
products.

The range includes liquid and powder formulations combining the following active substances among
others.

Phenoxyethanol Glyceril Laurate

Benzyl Alcohol Ethylhexylglycerin
Dehydroacetic Acid Gluconolactone
Sorbic Acid / Potassium Sorbate Caprylyl Glycol
Benzoic Acid / Sodium Benzoate
Piroctone Olamine
 innovative preservation systems

SENSICARE® is a new range of preservatives based on active substances with improved eco-
toxicity.

Inspired in the microbial control technology from the food industry, Chemipol started a modern research
program to develop innovative preservatives for the personal care industry.

The objective was to decrease the amount of biocidal actives in contact with the skin while, at the same
time, ensuring optimum protection.

The successful result of this on-going research program is the preservatives range SENSICARE® based
on the concept of self-preservation and hurdle technology for the microbial control.
 organic acids

ORGANIC ACIDS AND ITS SALTS are considered together with

benzyl alcohol as a unique category respect human health because
Bacteria Organic acid
Lipid membrane
they are quickly metabolized (24 hours) and excreted of our body
through the common pathways.
The method of action of all organic acids are based in the protonated
acid form that enter in the cell crossing the membrane, only the
protonated can do this process the neutralized form it´s rejected by
the membrane.Inside of the cell the acid will be dissociated and
change the internal pH of microorganism. The bacteria need to pump
outside the protons and need to chapt the most quantity of Na to
neutralize this acid pH , this energy consumer process and the
internal pH cause a stress situation that becomes in the death of the
External aqueous phase

microorganism.
Bacteria can inactivate this method of action neutralizing inside the
cell the protonated acid with sodium and extract the neutralized form
out of the cell being rejected by the membrane again.
 boosting technology

Glyceryl Laurate method of action

For its acceptable toxicity and stability over a wide range of formulations,
phenoxyethanol has become an active present in a large number of preservation
Glyceryl monoester
systems.
Bacteria
Lipid membrane

Glyceril laurate is a mild natural based surfactant derived from glycerin and lauric
acid that boosts the antimicrobial efficacy of phenoxyethanol, acids and benzyl
alcohol by acting on the surface tension of the microorganisms’ cell membrane.

Glyceryl laurate also shows hair conditioning properties and it is a strategic

ingredient for non-grease skincare formulations.
Acts as a co-emulsifier with other surfactants.
Enhances the aesthetics of formulations with excellent rub-out
Creates superior stability in all types of emulsions.
External aqueous
phase
By its mechanism of action, it allows the development of cosmetic formulations
with lower concentration of preservative substances while providing optimal
preservation.
 SENSICARE® C 1000

SENSICARE ® C 1000 is a liquid preservative for personal care formulations based on phenoxyethanol and
glyceril laurate.

It combines the well-known preservation properties of the phenoxytanol, with its acceptable toxicity
profile and excellent stability in personal care formulations, with the boosting capacities of the glyceryl
laurate altogether with its properties as co-emulsifier, improves rub-out and enhanced stability.

Contact time (hours)

PRODUCT ppm product
10 23 35 47 58 71 96 144
SENSICARE C 1000 2000 - - - - - - -

SENSICARE C 1000 4000 - - - - - - - -
Phenoxyetanol 6000 - - - - - -


Phenoxyetanol 8000 - - - - - - - -
SENSICARE C 1090 4000 - - - - -



SENSICARE C 1090 6000 - - - - - - - -
SENSICARE® C 1000 microbiological profile

The balanced formulation of SENSICARE® C 1000 MIC SENSICARE C 1000

as preservative reduces the surface tension of the
microorganism’s cell membrane, disrupts it and 0,50%
inhibits the metabolic function, impairs the
0,45%
enzymatic activity and occurs microbe inactivation.
0,40%
SENSICARE® C 1000 is effective against gram-
0,35% 0,33%
positive bacteria, gram-negative bacteria, molds
and yeasts. It requires short contact time to control 0,30%
microbial growth and provides strong self- 0,25%
preservation properties. By its action, when used in 0,21%
a heavily contaminated system may occur loss of 0,20% 0,18%
active ingredients. 0,15%
0,10% 0,09%
0,10%

0,05%

0,00%
S. Aureus E. Coli P. Aeuroginosa C. Tropic A. Niger
SENSICARE® C 1000 usage

Dose of use
The typical use concentration of SENSICARE® C 1000 in rinse-off and leave-on products is from 0,8%
to 1,1%. The recommended dosage is below the maximum concentration authorized according to
the Cosmetics Directive 76/768/CEE.
It is especially active against gram-positive bacteria causing body odor, being recommended to
protect deodorant formulations.

Stability
SENSICARE® C 1000 is stable over a wide range of pH (up to pH 12), temperature (up to 80 ºC) and
hydrolysis. It is stable protecting inverse emulsions, direct emulsions and water soluble products.

Compatibility
SENSICARE® C 1000 is compatible with the most common raw materials used in personal care
formulations, anionic, no ionic and cationic surfactants, salts and pigments. used in water based no
surfactant cosmetics (serums or micellar water) it disperses in water giving a milky appearance,
when used in formulations that must be clear it is recommended the use of solubilizers, such as
ethoxylathed castor oil, anionic surfactants, polysorbate , emollients in general about 0.2 %.
Solubility
SENSICARE® C 1000 is partially soluble in water, totally soluble in polar solvents (propylene glycol,
propanol and acetone), totally soluble in polyalcohols (sorbitol), and is moderately soluble in aliphatic
solvents.
SENSICARE® C 1060 usage

Dose of use & applications

The typical use concentration of SENSICARE® C 1060 in rinse-off products and leave-on products is from 0,4 % to
0,8 %. The recommended dosage is below the maximum concentration authorized according to the Cosmetics
Directive 76/768/CEE 1,2%.
It is especially active against gram-positive bacteria causing body odor, being recommended to protect deodorant
formulations , include an specific fungicide.
Free Paraben / Booster Technology / Better efficiency against classic Phenoxyethanol

Stability
SENSICARE® C 1060 is stable over a wide range of pH (up to pH 8), temperature (up to 80 ºC) and hydrolysis. It is
stable protecting inverse emulsions, direct emulsions and water soluble products.

Compatibility
SENSICARE® C 1060 is compatible with the most common raw materials used in personal care formulations,
anionic, no ionic and cationic surfactants, salts and pigments. used in water based no surfactant cosmetics
(serums or micellar water) it disperses in water giving a milky appearance, when used in formulations that must be
clear it is recommended the use of solubilizers, such as ethoxylathed castor oil, anionic surfactants, polysorbate ,
emollients in general about 0.2 %.
Solubility
SENSICARE® C 1060 is partially soluble in water, totally soluble in polar solvents (propylene glycol, propanol and
acetone), totally soluble in polyalcohols (sorbitol), and is moderately soluble in aliphatic solvents.
SENSICARE® C 1090 usage

Dose of use & applications

The typical use concentration of SENSICARE® C 1090 in rinse-off products 1060 in rinse-off products
and leave-on products is from 0,9% to 1,1%. The recommended dosage is below the maximum
concentration authorized according to the Cosmetics Directive 76/768/CEE.
It is especially active against gram-positive bacteria causing body odor, being recommended to
protect deodorant formulations.
Free Paraben / Booster Technology / Better efficiency against classic Phenoxyethanol

Stability
SENSICARE® C 1090 is stable over a wide range of pH (up to pH 12), temperature (up to 80 ºC) and
hydrolysis. It is stable protecting inverse emulsions, direct emulsions and water soluble products.

Compatibility
SENSICARE® C 1090 High concentrations of surfactants can decrease its effectiveness. is
compatible with the most common raw materials used in personal care formulations, anionic, no
ionic and cationic surfactants, salts and pigments.
Solubility
SENSICARE® C 1090 is soluble in water, totally soluble in polar solvents (propylene glycol, propanol
and acetone), totally soluble in polyalcohols (sorbitol), and is moderately soluble in aliphatic solvents.
SENSICARE® C 3300 usage

Dose of use & applications

The typical use concentration of SENSICARE® C 3300 in rinse-off and leave-on products is from 0,8%
to 1,1%. The recommended dosage is below the maximum concentration authorized according to
the Cosmetics Directive 76/768/CEE.
It is especially active against gram-positive bacteria causing body odor, being recommended to
protect deodorant formulations.
Free Paraben / Free Phenoxyethanol / Booster Technology /Better efficiency against classic Benzyl
Alcohol / Green cosmetics / Ecolabel compliment
Stability
SENSICARE® C 3300 is stable over a wide range of pH (up to pH 12), temperature (up to 80 ºC) and
hydrolysis. It is stable protecting inverse emulsions, direct emulsions and water soluble products.
Compatibility
SENSICARE® C 3300 is compatible with the most common raw materials used in personal care
formulations, anionic, no ionic and cationic surfactants, salts and pigments. used in water based no
surfactant cosmetics (serums or micelar water) it disperses in water giving a milky appearance,
when used in formulations that must be clear it is recommended the use of solubilisers, such as
ethoxylathed castor oil, anionic surfactants, polysorbate , emollients in general about 0.2 %.
Solubility
SENSICARE® C 3300 is partially soluble in water, totally soluble in polar solvents (propylene glycol,
propanol and acetone), totally soluble in polyalcohols (sorbitol), and is moderately soluble in aliphatic
solvents.
SENSICARE® M 4200 usage

Dose of use & applications

The typical use concentration of SENSICARE® M 4200 in rinse-off products and in leave-on products is from 1% to
2%. The recommended dosage is below the maximum concentration authorized according to the Cosmetics
Directive 76/768/CEE.
It is especially active against gram-positive bacteria causing body odor, being recommended to protect deodorant
formulations.
Free Paraben / Free Phenoxyethanol / Booster Technology / Better efficiency against classic Sodium Benzoate /
Preservative for all different types of face products / Ecocert Preservative

Stability
SENSICARE® M 4200 is stable over a wide range of pH (up to pH 7) but the safety area it´s near 5,5, resistant to
temperature (up to 80 ºC). It is stable protecting inverse emulsions, direct emulsions and water soluble products.

Compatibility
SENSICARE® M 4200 is compatible with the most common raw materials used in personal care formulations,
anionic, no ionic and cationic surfactants, salts and pigments.
Don´t blend with ascorbic acid , pH stability need to be checked if the pH drop buffer the system ,the buffer can be
sodium lactate/lactic acid , sodium citrate / citric acid ( proportion 1 m4200/ 2 buffer)

Solubility
SENSICARE® M 4200 is soluble in water, totally soluble in polar solvents (propylene glycol, propanol and acetone),
totally soluble in polyalcohols (sorbitol), and aliphatic solvents.
 risk evaluation

Spoilage risks
0% of probability of spoilage

1. Water Adequate growing medium

2. Ingredients Nutritive elements (organic matter and microelements)

3. Conditions pH, T, growing conditions, oxygen content

4. Lack of hygiene Storage, Production, Filling, Usage

5. Lack of protection Under dosage or inadequate preservative

100% of probability of spoilage

It is vital important for the right prevention policy the identification, elimination and control of
al the possible contamination focuses in the production site and chain of use.
 barrier technology

Preservative
SENSICARE C
Membrane-actives • Phenoxyethanol
• Benzyl alcohol
• Glyceryl Laurate
• Organic acids & salts
• EthylHexylGlycerin
Antioxidants • Piroctone Olamine
• Caprylyl Glycol
SENSICARE FP
Quelating Agents • Hydroxyacetophenone
• Tocopherol
• EDTA
• BHT
• Glutamic derivate
Available water
chapters
• Glycols
pH buffers • Glycerin
SENSICARE M • Polyalcohol
4200
• Gluconolactone M4200
• Lactic acid
• Citric acid
AW AVAILABLE WATER

Water Activity Types of proliferable Microorganisms TYPE OF COSMETIC Common Aw

0.96 to 0.99 Gram-positive and Gram-negative bacteria
Foundation 0.68
(e.g. Ps. species), mold and yeasts Hand Cream 0.96
0.90 to 0.95 Several Gram-negative and most Gram- Loose Body Powder 0.76
positive bacteria (e.g. Enterobacter aerogenes, Lipstick 0.68
Escherichia coli, Bacillus species), mold and
Mascara 0.96
yeasts
Gram-positive bacteria (e.g. S. aureus), mold Powdered Eyeshadow 0.76
0.80 to 0.89
and yeasts Shampoo 0.99
0.70 to 0.79 Halophilic bacteria, mold and yeasts Shampoo Conditioner 0.97
0.65 to 0.69 Osmotolerant yeasts Toothpaste 0.86
Below 0.6 None Wet/Dry Eyeshadow 0.57
Water Activity Level Antimicrobial Spectrum of a Preservative for Inclusion
Below 0.6 Inclusion of a preservative system may not be necessary.
0.70 – 0.79 Preservative system needs to be active against yeast and mold.
0.80 - 0.89 Preservative system needs to be active against Gram-positive bacteria, yeast and
mold.
Preservative system needs to have a broad spectrum of antimicrobial activity (e.g.
0.90 – 0.99
Gram-negative and Gram-positive bacteria, yeast and mold)
Self protecting formulations / Low sensitization preservative system

• PRESERVATIVE (PHENOXYETHANOL , BENZYL ALCOHOL , ORGANIC ACIDS/SALTS, PIROCTONE OLAMINA)

• BOOSTER (Glyceryl Laurate , Ethylhexylglycerine , Gluconolactone , Caprilyl glycol)
0,5 - 2%

• Aw CHAPTERS Glycols , Glycerin , Alcohols , Polialcohols

2 - 5%

• CHELATINGS L-glutamic acid N,N-diacetic acid, EDTA , Policarboxylates

• ANTIOXIDANTS Hidroxyacetophenone , BHT , THBQ , Tocopherol
0,1 - 0,2%
Benefits of SENSICARE® innovative preservation systems

CATEGORY
Product Face Face Shaving Body Sun Hair Decorative Wet
Body care Hair care Hair styling
cleansing care products cleansing protection cleansing cosmetics wipes

SENSICARE C 1000











SENSICARE C 1040          

SENSICARE C 1045          

SENSICARE C 1055          

SENSICARE C 1060











SENSICARE C 2010 


 


SENSICARE C 3000








SENSICARE C 3300











SENSICARE M 4200 


 



highly recommended  recommended
possible

 SENSICARE® preservative free

• LESS ODOUR • TESTED ANTIMICROBIAL EFFICACY ON

• LESS COLOUR • WATER BASE
• NO SIDE EFFECTS • OW EMULSION
• NO SENSITIZATION • WO EMULSION
• SERUM
• ANIONIC SURFACTANTS
• CATIONIC SURFACTANTS
AOX /
BIOFLAVONOIDS
QUELATING
/ POLYPHENOLS
AGENTS

GLYCERYL GLYCOLS /
ESTERS / ACIDS GLYCERYN
• STABILITY TESTED ON PERSONAL
CARE FORMULATIONS
• MICELLAR WATER
HANDCREAM
• BETTER PERFORMANCE • BODY CREAM
• BETTER COMPATIBILITY • PROTEIN SERUM
• WIDE PH RANGE • HAIR CONDITIONER
• HIGH TEMPERATURE RESISTANCE • SHAMPOO
 preservative free testing

SENSICARE ® FP preservative free preservation solutions for personal care have been tested on several
frame formulations in order to verify the following parameters.

Compatibility: There is no affectation in the appearance and properties of the personal care product.

Stability: There is no affectation of the SENSICARE® preservation solution at dose level in the personal
care product.

Efficacy: The personal care product is rightly protected

 frame formulations

Micellar water (MW) Natural face cream (NFC)

Aqua/Water, Aqua/Water
Rosa Damascena Flower Water, Butyrospermum Parkii Butter / Butyrospermum Parkii (Shea) Butter
Citrus Aurantium Dulcis Fruit Water / Citrus Aurantium Dulcis Caprylic / Capric Triglyceride
(Orange) Fruit Water Prunus Amygdalus Dulcis Oil / Prunus Amygdalus Dulcis (Sweet Almond) Oil
Poloxamer 184 Glycerin
Glycerin Cetyl Alcohol
Coco-Glucoside Cetearyl Alcohol
Propylene Glycol Glyceryl Stearate
Calendula Officinalis Flower Extract Aloe Barbadensis Leaf Juice
Calcium Gluconate Olus Oil/Vegetable Oil
Citronellol Potassium Palmitoyl Hydrolyzed Wheat Protein
Citral Argania Spinosa Kernel Oil
Citrus Aurantium Dulcis Peel Oil/Citrus Aurantium Dulcis (Orange) Peel Oil
Hydrolyzed Caesalpinia Spinosa Gum / Caesalpinia Spinosa Gum
Glycine Soja Oil / Glycine Soja (Soybean) Oil
Tocopherol
Xanthan Gum
Sodium Phytate
Beta Sitosterol
Squalene
Alcohol
Limonene
Linalool
Citral
Citronellol
 frame formulations

Anti-aging serum (AAS)

Aqua/Water Retinyl Palmitate
Glycerin Hydroxypropyl Cyclodextrin
Paraffinum Liquidum / Mineral Oil Ascorbyl Palmitate
Persea Gratissima Oil / Persea Gratissima (Avocado) Oil Palmitoyl Tripeptide – 38
Octyldodecanol Xanthan Gum
Prunus Amygdalus Dulcis Oil / Prunus Amygdalus Dulcis (Sweet Almond) Oil Parfum / Fragrance
Caprylic/Capric Triglyceride BHT
Simmondsia Chinensis Oil / Simmond sia Chinensis (Jojoba) Seed Oil Disodium EDTA
Butyrospermum Parkii Butter / Butyrospermum Parkii Butter (Shea) Butter Sodium Hydroxide
Dimethicone Linalool
Lecithin Butylphenyl Methylpropional
Bisabolol Hydroxycitronellal
Sodium Hyaluronate Limonene
Hydrolyzed Collagen
Tocopheryl Acetate
Allantoin
Acrylates / C10 – 30 Alkyl Acrylate Crosspolymer
Panthenol
 frame formulations

Moisturizing facial cream (MFC)

Aqua/Water Dimethicone / Vinyl Dimethicone Crosspolymer
Butyrospermum Parkii Butter / Butyrospermum Parkii Butter (Shea) Butter Alcohol
Cyclopentasiloxane Acrylates / C10 – 30 Alkyl Acrylate Crosspolymer
Isohexadecane Cetyl Alcohol
Prunus Amygdalus Dulcis Oil / Prunus Amygdalus Dulcis (Sweet Almond) Oil Xanthan Gum
Steareth – 2 BHT
Cetearyl Isononanoate Disodium EDTA,
Simmondsia Chinensis Seed Oil / Simmondsia Chinensis (jojoba) Seed Oil Sodium Hydroxide
Steareth – 21 Potassium Phosphate
Glycerin Hexyl Cinnamal
Zea Mays Oil / Zea Mays (Corn) Oil Linalool
Parfum/Fragrance Limonene
Lecithin Hydroxyisohexyl 3 – Cyclohexene Carboxaldehyde
Tocopheryl Acetate Alpha – Isomethyl Ionone
Allantoin Benzyl Salicylate
Rosa Moschata Seed Oil Coumarin
Centella Asiatica Extract
Helianthus Annuus Seed Oil / Helianthus Annuus (Sunflower) Seed Oil
Sodium Hyaluronate,
Rosmarinus Officinalis Leaf Extract / Rosmarinus Officinalis (Rosemary) Leaf
Extract
Dimethicone
 frame formulations

External oleo phase moisturizing cream (EOPMC)

Aqua / Water Helianthus Annuus Seed Oil / Helianthus Annuus (flower) Seed Oil
Isohexadecane Rosmarinus Officinalis Leaf Extract / Rosmarinus Officinalis (Rosemary) Leaf
Isopropyl Palmitate Extract
Prunus Amygdalus Dulcis Oil / Prunus Amygdalus Dulcis (Sweet Almond) Oil BHT
Glycerin Hexyl Cinnamal
Rosa Moschata Seed Oil Limonene
Caprylic / Capric Triglyceride Linalool
Cyclopentasiloxane Alpha – Isomethyl Ionone
PEG – 30 Dipolyhydroxystearate Butylphenyl Methylpropional
Magnesium Sulfate Hydroxyisohexyl 3 – Cyclohexene Carboxaldehyde
Zea Mays Oil / Zea Mays (Corn) Oil Citronellol
Hyaluronic Acid Hydroxycitronellal
Tocopheryl Acetate Citral
Retinyl Palmitate
Centella Asiatica Extract
Parfum / Fragrance
Hydrogenated Castor Oil
 frame formulations

Bath gel (BG) Natural moisturizing cream (NMC)

Aqua / Water Aqua/Water
Sodium Laureth Sulfate Coco-Caprylate / Caprate
Cocamidopropyl Betaine Isostearyl Isostearate
PEG – 7 Polyglyceryl – 3 Polyricinoleate
Glyceryl Cocoate Caprylic / Capric Triglyceride
Parfum / Fragrance Oryza Sativa Bran Oil / Oryza Sativa (Rice) Oil
Decyl Glucoside Glycerin
Glycerin Aloe Barbadensis Leaf Juice
Aloe Barbadensis Leaf Juice Prunus Armeniaca Kernel Oil / Prunus Armeniaca (Apricot) Kernel Oil
Styrene / Acrylates Copolymer Sodium Chloride
Glycol Distearate Hydrogenated Apricot Kernel Oil
PEG / PPG – 18 / 18 Dimethicone Parfum / Fragrance
PEG – 4 Rapeseedamide Hyaluronic Acid
Hydroxypropyl Guar Hydroxypropyltrimonium Chloride Glycine Soja Oil / Glycine Soja (Soybean) Oil
Cocamide MEA Tocopherol
Laureth – 10 Beta – Sitosterol
Avena Sativa Kernel Extract / Avena Sativa (Oat) Kernel Extract Squalene
Panax Ginseng Root Extract Tocopherol
Sodium Chloride Linalool
Tetrasodium EDTA
Sodium Hydroxide
Citric Acid
Linalool
 tests results

The different frame formulations have been treated with different dosages of the SENSICARE range for preservative free preservation
solution.
Five synthetic frame formulations with 1.5 and 2.0 %
SENSICARE® FP 1
Two natural frame formulations with 1.0 and 1.5 %
SENSICARE ® NAT

MW NFC AAS MFC EOMPC BG NMC

NAT 1.0 % No Tested A No Tested No Tested No Tested No Tested A
1.5 % No Tested A No Tested No Tested No Tested No Tested A
FP 1 1.5 % A No Tested B B B A No Tested
2.0 % No Tested No Tested A A A No Tested No Tested

The test has been carried out according to

Test for efficacy of antimicrobial preservation (European Pharmacopeia 8th edition)

The results have been given according to the Criteria A and B defined by the method.
 SENSICARE® FP 1

INCI
Hydroxyacetophenone – antioxidant, anti-irritant*, emulsion stabilizer, antimicrobial
Glyceryl Laurate – emollient, emulsifier
Propylene glycol – humectant, skin conditioning
DOSE
1 – 2%
pH
2 – 10

TARGETED FOR
Baby care, facial care, eye contour, oral care, wet wipes, make up, clear cosmetics

* COX-Z assay, enzyme activity

 SENSICARE® FP 1
Dose of use & applications
The typical use concentration of SENSICARE® FP 1 in rinse-off products and in leave-on products is from 1% to 2%. The recommended
dosage is according to the Cosmetics Directive 76/768/CEE.
Free Paraben / Free Phenoxyethanol / Free benzyl alcohol
Booster Technology for free preservative formulations
Multifunctional activity due to its components potentiating the anti-oxidizing, skin conditioning and wetting characteristics of the personal
care products

Stability
SENSICARE® FP 1 is stable over a wide range of pH (up to pH 10), temperature (up to 80 ºC) and hydrolysis. It is stable protecting
inverse emulsions, direct emulsions and water soluble products. Recommended storage temperature up to 20ºC

Compatibility
SENSICARE® FP 1 is compatible with the most common raw materials used in personal care formulations, anionic, no ionic and cationic
surfactants, salts and pigments.
SENSICARE® FP 1 used in water based no surfactant cosmetics (serums or micellar water) it disperses in water giving a milky
appearance, when used in formulations that must be clear it is recommended the use of solubilizers, such as ethoxylathed castor oil,
anionic surfactants, polysorbate , emollients in general about 0.2 %.

Solubility
SENSICARE® FP 1 is soluble in water, totally soluble in polar solvents (propylene glycol, propanol and acetone), totally soluble in
polyalcohols (sorbitol), and aliphatic solvents.
 SENSICARE® NAT

INCI
Citrus paradisi (grapefruit) Fruit Extract
Citrus paradisi (grapefruit) Seed Extract
Citrus aurantium extract humectant, skin conditioning, parfum, antioxidant
Citrus sinensis extract
Citrus reticulate (Tangerine) Peel extract
Vegetal glycerine – humectant, moisturizer
Ascorbic acid – antioxidant
Lactic acid – acid
Citric acid – acid
DOSE
1.0 – 2.0 %
pH
2 – 10
TARGETED FOR
Baby care, facial care, wet wipes, make up, green cosmetics, Cosmos, Ecocert, Natrue
 SENSICARE® NAT
Dose of use & applications
The typical use concentration of SENSICARE® NAT in rinse-off products and in leave-on products is from 1% to 1,5%. The
recommended dosage is according to the Cosmetics Directive 76/768/CEE.
Natural origin preservation for free preservative formulations
Multifunctional activity due to its components potentiating the skin and hair conditioning, anti-oxidizing and wetting characteristics of the
personal care products and a fresh orange fragance.
Free Paraben / Free Phenoxyethanol / Booster Technology / Better efficiency against classic Sodium Benzoate / Preservative for all
different types of green Ecocert / cosmos / Natrue cosmetic

Stability
SENSICARE® NAT is stable over a wide range of pH (up to 10), temperature (up to 80 ºC) and hydrolysis. It is stable protecting inverse
emulsions, direct emulsions and water soluble products.

Compatibility
SENSICARE® NAT is compatible with the most common raw materials used in personal care formulations, anionic, no ionic and cationic
surfactants, salts and pigments. Incidence in the colour need to be check cause acid pH obtain light yellow coloration and higher pH
increase make it intense

Solubility
SENSICARE® NAT is soluble in water, totally soluble in polar solvents (propylene glycol, propanol and acetone), totally soluble in
polyalcohols (sorbitol).
 SENSICARE® NAT
MIC and MBC
Minimum Inhibitory Concentration (MIC) is understood as the lowest concentration of the preservative solution that inhibits the growth
of a determined microorganism.
Minimum Bactericidal Concentration (MBC) is understood as the lowest concentration of the preservation solution that kills 99.9 % of a
determined bacteria.
The assays performed on SENSICARE® NAT have shown that the its effectiveness in terms of MIC and MBC is nearly the same, showing
therefore an antibacterial activity at dose level.

Mechanism
The complex formulation of SENSICARE® NAT facilitate a multiple path for the interaction of the different active ingredients present in the
system with the microorganisms which will lead to them to a failure and death.
This multiple mechanism of activity increases the antibacterial properties.

Multifunctionality
The different components of SENSICARE® NAT are not strictly antibacterial agents, and provide to the formulation where used other
properties.
The natural origin of these components of SENSICARE® NAT is responsible for these properties such as antioxidant, humectant,
conditioning etc.
 SENSICARE® NAT

Natural extracts
The use of natural sources provides a rich blend of active ingredients that provide a great variety of chemistry.
Many of the components of these extracts have antibacterial properties.
The multiplicity of active ingredients with antibacterial activity ensures a broader activity spectra.
Moreover, other properties are associated to them providing further benefits to their used in personal care formulations.
Phenolic compounds are within these components present in different forms of the family of flavonoids (catechins, epicatechin,
procyanidin, etc.).
Other elements of much interest are ascorbic acid, tocopherols, citric acid, limonoids, sterols, etc.

Flavonoids
Flavonoids are a family of hydroxylated phenolic compounds naturally found in plants and fruits.
They are found in our daily diet.
They provide many benefits to our health.
They have antibacterial properties.
SENSICARE® BIOPOL ® Rinse off Selection guide

RINSE OFF

• 0,2% BIOPOL C 30 (CMIT/MIT+ BENZYL ALCOHOL)

IF CMIT/MIT IT´S ACCEPTED • 0,1% BIOPOL IBC (CMIT/MIT + BRONOPOL)

• 0,1% BIOPOL C 20 (CMIT/MIT)

• 0,6-0,8% BIOPOL DHN (DMDMHYDANTOINE)

IF CMIT/MIT ARE BANNED
• 0,4-0,8% BIOPOL DHK (DMDMHYDANTOINE + POTASSIUM SORBATE)
BUT IT´S ACCEPTED
FORMALDEHYDE RELEASERS & • 0,8-1,5% SENSICARE C 2010 (SODIUM BENZOATE / POTASIUM SORBATE)
SODIUM BENZOATE
• 1-2% SENSICARE M 4200 (SODIUM BENZOATE + GLUCONOLACTONE )
/POTASSIUM SORBATE

IF CMIT/MIT , MIT , FR , • 0,8 - 1 % SENSICARE C 1000 (PHENOXYETHANOL + GLICERYL LAURATE)

ARE BANNED BUT IT´S ACCEPTED • 0,4-0,8 % SENSICARE C 1060 (PHENOXYETHANOL + GLICERYL LAURATE + PIROCTONE OLAMINE)
PHENOXYETHANOL
• 0,9-1,1 % SENSICARE C 1090 (PHENOXYETHANOL + ETHYLHEXYLGLYCERINE)
SENSICARE® BIOPOL ® LEAVE ON Selection Guide

IF PARABENS ARE ACCEPTED • 0,6 - 0,8 % BIOPOL PB 6 (METHYL + ETHYL + PROPYL PARABEN + PHENOXYETHANOL )

• 0,8 - 1 % SENSICARE C 1000 (PHENOXYETHANOL + GLICERYL LAURATE)

IF IT´S ACCEPTED • 0,5 - 0,6 % SENSICARE C 1060 (PHENOXYETHANOL + PIROCTONE OLAMINE+ GLICERYL LAURATE)
PHENOXYETHANOL
• 0,9 - 1 % SENSICARE C 1090 (PHENOXYETHANOL + ETHYLHEXYLGLICERINE)

IF IT´S ACCEPTED • 0,8 - 1 % SENSICARE C 3300 (BENZYLALCOHOL + GLICERYL LAURATE)

BENZYLALCOHOL SODIUM
BENZOATE /POTASSIUM SORBATE • 0,8 - 1 % SENSICARE C 3000 (BENZYLALCOHOL + DEHIDROACETIC ACID)

& ECOLABEL / • 0,8 - 1,5 % SENSICARE M 4200 (SODIUM BENZOATE + GLUCONOLACTONE)

ECOCERT/COSMOS

• 1 - 2 % SENSICARE FP 1
IF IT´S NOT ACCEPTED
PHENOXYETHANOL
BENZYLALCOHOL SB/PS • 1 - 2% SENSICARE NAT
Mercados
ACRIPOL T

ACRIPOL T is a complete range of thickeners for detergents.

This product range are developed based in acrylic polymers and copolymers. Performance of this
kind of thickeners is to modify the viscosity of the treated products stabilizing emulsions or
generating a gel consistence in transparent products.
Easy handling and direct use without neutralization are the characteristics of this thickeners range.

PRODUCT APPLICATION POLIMER IONICITY % ACTIVE PRESENTATION pH APPLICATION VISCOSITY TRANSPARECY RECOMENDATION

T 111 DETERGENCY ACRILIC CATIONIC 56 OIL 2-5 20.000 NO Softener

EMULSION Acid detergents
T 112 DETERGENCY ACRILAMIDE ANIONIC 56 WATER 2-5 20.000 YES Acid detergents
EMULSION
T 132 DETERGENCY COPOLIMER ANIONIC 50 WATER 6 - 14 20.000 YES Degreasers
EMULSION Alcaline detergents
Mercados
ACRIPOL T

ACRIPOL T is a complete range of thickeners for cosmetics and personal care.

This product range are developed based in acrylic polymers and copolymers. Performance of this
kind of thickeners is to modify the viscosity of the treated products stabilizing emulsions or
generating a gel consistence in transparent products. Easy handling and in some cases direct use
without neutralization are the characteristics of this thickeners range.
PRODUCT APPLICATION POLIMER IONICITY % ACTIVE PRESENTATION pH APPLICATION VISCOSITY TRANSPARECY RECOMENDATION

T 210 COSMETIC COPOLIMER ANIONIC 50 WATER 2 - 11 1% / 20.000 NO Skin care emulsions

DISPERSION
T 220 COSMETIC POLIACRILAMIDE ANIONIC 57 WATER 2 - 11 2% / 32.000 NO Skin care emulsions
DISPERSION

T 230 COSMETIC POLYQUAT CATIONIC 53 WATER 2 - 11 2% / 45.000 NO Hair conditioners

DISPERSION
T 250 COSMETIC COPOLIMER ANIONIC 30 WATER 2-9 1% / 7.000 YES Surfactant base
EMULSION
T 260 COSMETIC COPOLIMER ANIONIC 20 WATER 2 - 10 10% / 100,000 YES Gels , extracts
EMULSION
T 280 COSMETIC CARBOMER ANIONIC 100 SOLID 3 - 12 0,2% / 30.000 YES General Applications
GRANULAR
ACRIPOL OP

ACRIPOL OP is a range of opacifiers for detergents , cosmetics and personal care. This line of
products are based in a styrene/acrylate dispersion in water.
Easy handling and use is the characteristic of this opacifiers. It is recommended a pre-dilution in
water at 10-20%.

ACRIPOL OP 313 is a water based styrene / acrylate copolymer developed to be used in

cosmetics and detergents with hydroalcoholic blends. It is stabilized in acidic pH

INCI Styrene / acrylates copolymer

DENSIPOL

Defoamers are products designed to avoid the problems caused by the presence of undesirable foams in the
production sequence, filling actions and application action. Even though are products to preserve the foam
formation and also to eliminate formed foams.

• Industrial grade
• DENSIPOL SI / DENSIPOL RMB / DENSIPOL SI 30
SILICONES • Food & Cosmetic grade
• DENSIPOL SI 99 / SENSICARE A 1000

• OE/OP Copolymers OE/OP and ethoxylathed fatty

alcohols
OE/OP
• DENSIPOL DF 152 / DENSIPOL DF 800
COPOLYMER • Remain transparency and high performance in high
temperature Automatic/CIP cleanings
 Chemipol S.A.
Joan Monpeó 149 · 08224 Terrassa (Barcelona) · Spain
Tel.: +34 937 831 044 · Fax: +34 937 837 580

www.chemipol.com

© 2018 Chemipol S.A.