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Definition:
It is the placement of a tube into the trachea (windpipe) in order to maintain an open airway in
patients who are unconscious or unable to breathe on their own. Oxygen, anesthetics, or other
gaseous medications can be delivered through the tube.
Neurologic:
Inadequate chest wall function (eg, in patient with Guilain Barre syndrome)
Absence of protective airway reflexes ( eg,cough, gag).
Glassgow coma score≤ 8.
Others:
During anaesthesia.
Poisoning
Anaphylactic reaction
Endotracheal Intubation
Orotracheal intubation :
In endotracheal intubation an endotracheal tube is passed through the mouth, larynx, and
vocal cords, into the trachea
Nasotracheal intubation:
In this type of intubation a tube is passed through the nose, larynx, vocal cords, and trachea
Indications:
Anticipated difficult intubation (upper airway abnormality)
Endotracheal intubation when neck extension is not desirable (cervical spine injury,
rheumatoid arthritis
Contraindications:
Inability to oxygenate
Major bleeding
Advantages
Excellent airway visualization
Minimal hemodynamic stress
Disadvantages
Costs associated with the need for special equipment and skill
A study was conducted by Zhang Guo-hua et all to assess the effect of fiberoptic
bronchoscope compared with direct laryngoscope on hemodynamic responses to orotracheal
intubation in beijing china. The intubation time was significantly longer in the FOB group
((34.9±8.5) seconds) than in the DLS group ((27.8±10.7) seconds) (P<0.05). No significant
differences were seen in the demographic data and in the baseline values of BPs and HRs No
significant differences were in BPs at any time point in the maximal values of BPs during the
observation between the two groups. HRs at intubation and 1 minute after intubation were
significantly higher in the FOB group than in the DLS group.
3. Blind nasotracheal intubation:
it is the passage of tube through the nose into the trachea without using a laryngoscope.
The blind nasotracheal technic is especially valuable for intubating spontaneously breathing
patients with or without sedation, or under general anesthesia.
It may be used in elective as well as selected emergent situations.
4. Retrograde Intubation:
A J-tip guide wire is introduced percutaneously through the cricothyroid membrane, and
advanced into the retropharynx
The tip is retrieved from the oral cavity, and the wire is used to guide an oral endotracheal tube
into the trachea
The procedure is relatively safe and simple alternative if other techniques fail or not possible
Premedication:
1. Lidocaine
Description: Lidocaine is a local anesthetic of the amide class. It’s mechanism of action is by stabilizing
the membranes of neuronal tissue through the inhibition of sodium passage which is needed to conduct
impulses.
Precautions: Patients with heart block, severe hypovolemia, congestive heart failure.
Dosage: 1-2 mg/kg 3-5 minutes prior to intubation.
Route: Intravenous
2. Atropine
Description: it is rapid onset acetylcholine receptor antagonist . The vagolytic effect also blocks the
bradycardia caused by airway manipulation. It also reduces salivary and airway secretions.
3. Fentanyl
Description: Fentanyl is a highly potent opioid analgesic compound in the same family as morphine. It is
100 times more potent than morphine. Fentanyl has a rapid onset and short duration of action. It is
cardiovascularly stable and tends to support blood pressure. Respiratory depression is common and dose
dependent. It too, is accentuated by the presence of other depressants. Fentanyl possess some sedating
properties. It’s effects can be reversed with naloxone.
Precautions: Elderly, hypovolemic, or patients with other sedatives should have reduced dosages.
Route: Intravenous
Induction Agents
1. Sodium Thiopental
Description: Sodium thiopental (STP) is in the barbiturate class of agents. It is ultrashort - acting, has a
rapid onset with the induction of hypnosis and amnesia. Cardiac depression and vasodilatation with
hypotension can be severe. It is a potent respiratory depressant. STP is primarily used for the induction
of anesthesia.
Precautions: STP will cause hypotension from cardiac depression and therefore should be used with
caution or in reduced doses in patients who are or are at risk of hypovolemia and/or hypotensive,
hypertensive, cardiac history, elderly patients.
Dosage: 3-5mg/kg
Route: Intravenously
2. Etomidate
Description: Etomidate is a nonbarbiturate induction agent that lacks analgesic properties as well. It has
minimal cardiovascular effects and maintains blood pressure. It too, is a potent respiratory depressant.
Etomidate has been reported to decrease adrenal steroid response. Myoclonus (jerky, muscular
contractions) may be seen after administration. It has a rapid onset with a short duration of action.
Indications: As induction agent, particularly useful in patient at risk of hypovolemia, with history of
cardiac disease, or hypertension.
Precautions: Patients with hypertension, hypovolemia, or elderly may need decreased dosages.
Route: Intravenous
3. Ketamine
Precautions: Hypotension may be seen in patients who are relying on their sympathetic drive; use
caution in patients with hypertension or cardiac disease; hallucinations and emergence reactions are
common.
Dosage: 1 - 2 mg/kg
Route: Intravenous
4. Propofol
Description: Propofol is a white, milky, alcohol emulsion that produces a rapid onset of anesthesia with
no analgesic effects. It is rapidly metabolized and redistributed to give a short duration of action. It is a
potent vasodilator and cardiac depressant with hypotension seen after administration. It is a potent
respiratory depressant.
Precautions: Elderly patients, hypovolemic patients, hypertensive patients, reduced dosages are needed;
may cause vascular irritation if given in small vein; emulsion supports growth of bacteria and is intended
for single use.
Dosage: 2 mg/kg
Route: Intravenous
5. Midazolam
Description: Midazolam is a benzodiaezepine in the same family as diazepam. It is short acting and has
a fairly rapid onset. It is possesses antianxiety, amnesic, anticonvulsant, and sedating properties for
which it is commonly used for. It has no analgesic properties. It has the potential to decrease blood
pressure, and is a respiratory depressant as well, which is increased if another depressant is already
present (alcohol, narcotics). May be reversed by antagonist flumazenil.
Indications: Sedation
Precautions: Respiratory depression may worsen intracranial pressure. Use reduced dosages in elderly,
hypovolemic, or patients with other depressants present.
Route: Intravenous
Neuromuscular Blockers
1. Succinylcholine
Precautions: Use with caution, if at all, in any patients suspected of having a difficult airwayDosage: 1-2
mg/kg
Route: Intravenous
2.Rocuronium
Route: Intravenous.
Procedure OF RSI
All equipment is available and functional (laryngoscopes, ETT, suction, # 11 scalpel, pulse
oximeter/end tidal CO2 monitor, ECG and BP monitor).
IV access is established.
Preoxygenation with non -rebreather mask or AMBU bag - valve assisted ventilations with the
application of cricoid pressure.
.Endotracheal tube placement is confirmed (listening for bilateral equal breath sounds, absence
of breath sounds over the stomach, esophageal detector, presence of end tidal CO2, observing
symmetrical chest expansion).
Tube is secured.
Complications of RSI
Cardiac collapse
Exacerbation of an elevated ICP may occur if an inappropriate RSI is used.
3months- 1.0(straight)
3years
3yr-12yr 2.0(straight or curved)
Types of cuffs:
High pressure low volume cuff: high pressure, low volume cuff operates by distending a rubber
balloon around the tip of the tube, thus sealing the trachea. This carries the risk that the pressure within
the cuff can cause trauma to or necrosis of the tracheal wall.
Low pressure, high volume cuff: it has a much greater volume than the traditional cuff, and so
requires a lower inflation pressure to produce a seal. There is, therefore, less risk of trauma to the
trachea. However, there is a danger that, if the cuff is over-inflated, rupture of the trachea can occur. It is
important that only very low pressures should be used to inflate these cuffs.
PROCEDURE OF INTUBATION:
Preparation of Patient:
Obtain consent
Assessment of airway: assess for
1.Condition that associated with difficult intubation
Maxillofacial ,cervical or laryngeal trauma
Infection in airway: Retropharyngeal abscess, Epiglottitis
Tumor in oral cavity or larynx
Enlarge thyroid gland
Burn scar at face and neck
2.Interincisor gap : it is the distance between the upper and lower incisors. normal -> more than 3
cms. It is assessed to see to opening of mouth for inserting the laryngoscope.
3. Mallampati classification: This system is a method for quantifying the degree of difficulty of
endotracheal intubation based on amount of posterior pharynx that can be visualized.this
method gives an indirect means of evaluating the relative proportionality of the base of the
tongue and oropharynx. If the base of the tongue is proportional to the oropharynx then the
exposure of glottic inlet is will not be difficult. On the other hand , a disproportionately large
base of the tongue overshadows the larynx and perhaps makes the angle between the two more
acute preventing easy exposure of the larynx
Class 1- soft palate, fauces, entire uvula, tonsillor pillars are visible
Class 2- soft palate, fauces, part of uvula
Class 3- soft palate, base of uvula
Class4 – soft palate not visible at all
4.Laryngoscopic view:
Grade 1- most of the glottis visible
Grade 2- Only the posterior of the glottis visible
Grade 3- No parts of the glottis visible
Grade 4- not even glottis is visible
In grade 3 and 4 there is risk for difficult intubation.
5. Thyromental distance : Measure from upper edge of thyroid cartilage to chin with the head fully
extended. A short thyromental distance equates with an anterior larynx that is at a more acute angle and
also results in less space for the tongue to be compressed into by the laryngoscope blade.Thyromental
distance less than 6 cm may predict a difficult intubation
6. Flexion and extension of neck: it assess the feasibility to make sniffing position for intubation i.e
alignment of oral, pharyngeal and laryngeal axis into an arbitary straight line.
Positioning of the patient:Sniffing position is given. This position is given by flexion at lower
cervical spine and extension at atlanto occipital joint
Positionning In children: A sniffing position without hyperextension of
the neck is usually appropriate for infants and children .It is helpful to
place the towel under the child’s shoulder.
Prior to intubation:
Check the intubation equipment before beginning.
Attach the blade to the handle and be sure that the bulb illuminates
Attach suction to suction machine and be sure that suction is turned on.
If using a stylet, insert it into endotracheal tube
The tip of the stylet should be 1-2 cm proximal to distal end of endotracheal tube ,ensuring that
the stylet does not go through murphy eye
Prepare to monitor the patient’s heart rate, oxygen saturation levels and blood pressure
Steps of procedure:
Hand washing
Preoxygenate with 100% oxygen
Administer 0.01 – 0.02 mg/kg IV of atropine
Wear gloves
Laryngoscope handle is held with the left hand
Insert the laryngoscope blade in the patients right side of the mouth and sweep to the center of
the mouth
When a curved blade/ straight blade is used, the tip of the blade is advanced into the vallecula.
When a straight blade is used, the tip of the blade is inserted under the epiglottis
Apply sellick’s maneuver
Lift the laryngoscope blade in an upward motion
The handle must not be used with a prying motion, and the upper teeth must not be used as a
fulcrum
Visualize the vocal cords
Using the right hand, insert the endotracheal tube until you see the cuff pass through the vocal
cords. Advance the tube an additional ½ to 1 inch for proper placement.
Remove the laryngoscope carefully from the patients mouth
Remove the stylet from the endotracheal tube
Ventilate the patient
Check for proper placement
Observational methods to confirm correct tube placement:
- Direct visualization of the tube passing through the vocal
cords
- Clear and equal bilateral breath sounds on auscultation of the
chest
- Absent sounds on auscultation of the epigastrium
- Inflate the endotracheal tube’s cuff with 10 cc’s of air
- Equal bilateral chest rise with ventilation
- Fogging of the tube
- An absence of stomach contents in the tube
COMPLICATIONS:
At the time of intubation:
Failed intubation
Laryngospasm
Oesophageal intubation
Bronchial intubation
Airway perforation
Nasal , pharyngeal, laryngeal, uvular ,tracheal trauma
During extubation:
Difficult extubation
Aspiration of oral or gastric contents
After extubation:
Sore throat
Laryngeal oedema
Hoarseness
Superficial laryngeal ulcers
Laryngeal granuloma
Vocal cord paralysis
Tracheal stenosis
Assessment:
The nurse has a vital role in assessing the patient’s status
Physical assessment includes systematic assessment of all body systems, with and indepth focus
on respiratory system
Respiratory assessment includes respiratory rate and pattern, breath sounds, potential evidence
for hypoxia
Auscultate breath sounds of anterior and lateral chest bilaterally
Monitor for sign and symptoms of aspiration.
1. Nursing diagnosis
Risk for ineffective airway clearance related to increased secretions secondary to endototracheal
intubation or displacement of endotracheal tube
Goal:
Maintainance of patent airway
Nursing interventions:
Assess for the presence of secretions by lung auscultation at least every 2-4 hours
Clear the airway by suctioning. Frequency of suctioning should be determined by patient’s
assessment
Chest physiotherapy should be done
Position should be changed frequently
Nurse must monitor for the proper placement of ET Tube at least every 2 – 4 hours
2.Nursing diagnosis:
Risk for trauma and infection related to endotracheal intubation
Goal:
Prevention of trauma and infection
Nursing interventions:
The nurse must ensure that there is minimal pulling or distortion of tube in the trachea ; this
reduces the risk of trauma to the trachea.
Cuff pressure is monitored every 8 hourly to maintain the pressure at less than 25 cm of water
The nurse evaluates the for the presence of cuff leak
The nurse administer 0ral care frequently
The endotracheal tube should be retaped or secured every 24 hours and as needed
If the patient is nasally intubated, the nurse should remove the old tape or ties and clean the skin
around the ET tube with saline soaked gauze or cotton swab
If the patient is orally intubated, the nurse should remove the bite block ( if present) and the old
tape and ties and replace with the other one.
3. Nursing diagnosis:
Impaired verbal communication related to inability to produce speech secondary to endotracheal
intubation
Goal:
Fostering adjustment to nonverbal methods of communication
Nursing interventions :
The nurse assesses the patient’s communication abilities to evaluate for limitations
The nurse offers several appropriate communication approaches like writing pad and pencil or
magic slate, gesturing etc.
The nurse should make sure that the patient’s eyeglasses, hearing aids are available to enhance
the patient’s ability to communicate
The patient should be assisted to find the most suitable communication methods.
4. Nursing diagnosis:
Impaired mobility related to ventilator dependency
Goal:
Attainment of optimal mobility
Nursing interventions:
As muscle activity and mobility are beneficial as they stimulate respirations and improve morale
The nurse provide active and passive range of motion exercises every 6-8 hrly
The nurse assist the patient whose condition has become stable to get out of bed and to a chair
as soon as possible.
Conclusion
Endotracheal intubation is a boon for maintenance of patent airway in order to save the life
of a patient and it possess many advantages over other methods of airway management . This
statement is supported by an epidemeological study which was conducted by Kapadia, Farhad N,
Bajan to assess the rate of occurrence and nature of airway accidents in intubated patients Hinduja
National Hospital and Medical Research Center, Mumbai .Prospective recording of all airway
accidents in a 16-bed multidisciplinary intensive care unit was done. A total of 5,046 ventilated
patients intubated for 9,289 days during 4 yrs .Results of the study showed the total accident rate
was 36 of 5,046 patients during 9,289 intubated patient days; Researchers draw Conclusion that
Airway accidents occurred at low levels with even lower rates of resultant morbidity and mortality.
Tracheostomy accidents are more common than those with an endotracheal tube.
SUMMARY
BOOKS
1. Yadav Ajay. Short textbook of Anaesthesia. 2nd ed. Delhi: Academa publishers;2004.p.1-6.
2. Divekar M Vasumathi. Anaesthesia and Resuscitation. 2nd ed.New Delhi: Jaypee medical
publishers;2004.p. 74- 81.
3. Pinnock Colin. Fundamentals of anaesthesia. 1st ed.London: Greenwich Medical
publishers.2000.p.48-53
4. Henretig M Fred. Textbook of pediatric emergency procedures.1st ed. Pennysylvania: Williams
and Wilkins publishers. 2005.p. 178-233
5. Long C Barbara, Wilma J Phipps. Medical surgical Nursing. 3rd ed. Missouri: Mosby
publishers.1993.p.617-620.
JOURNALS
1. Bangari A, Puri G D. Murphy’s eye : go for the eye : learning fibreoptic Intubation. Anaesthesia
and intensive care 2009 jan; 37(1):176
2. Kapadia, Farhad N, Bajan. An epidemiological study was conductedTo assess the rate of
occurrence and nature of airway accidents in intubated patients. Critical care medicine 2000
mar;28(3): 659-664
INTERNET SOURCES
2. Depoix AP et all. A study to assess time for intubation, incidence of mechanical complications,
occurrence of bacteraemia caused by intubation. British Journal of
Anaesthesia[Seriaonline]2009 [cited2009 nov 30];103(6):867-73. Available from: URL:
http//www.bja.oxford journals.org
4. Neligan Pat. Intubation and Rapid Sequence Induction[ online]1999 [cited 2009 dec 1];
Available from: URL:http//www.ncbi.nlm.nih.gov.