T H E R A P E U T I C I N D E X

Zedex®DS
Zinc Sulphate

Description
Zedex DS contains Zinc Sulphate which is a source of Zinc which is an
essential trace element and involved in a number of body enzyme
systems. Zinc salts are used as supplements to correct Zinc deficiencies.
The consequences of Zinc deficiency are malformations of the brain,
eyes, bones, heart and other organs. Zinc is essential for the formation
and function of the immune system. Systems influenced by Zinc include
the reproductive, neurologic, immune, dermatologic and gastrointestinal
systems.

Indications
♦ Zinc deficiency states
♦ Growth retardation, respiratory tract infection, alopecia, dermatitis,
diarrhoea, immunologic dysfunction, psychological disturbances,
gonadal atrophy, impaired spermatogenesis, congenital malformations,
acrodermatitis enteropathica.

Dosage and Administration

→ Children under 10 kg :22.5 mg (2¼ tea spoonful) daily in
divided doses.
→ Children within 10 to 30 kg : 22.5 mg (2¼ tea spoonful) 1 to 3
times daily after food.
→ Adults and children over 30 kg : 45 mg (4½ tea spoonful) 1 to 3
times daily after food or as directed
by the physician.

Contraindication
It is contraindicated in patients with hypersensitivity to Zinc.

Precautions
Accumulation of Zinc may occur in case of renal failure.

Drug Interactions
Zinc may inhibit the absorption of concurrently administered
Tetracyclines, therefore, an interval of at least 3 hours should be allowed
while taking these products.

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Side Effects
♦ Zinc salts may cause abdominal pain and dyspepsia.
♦ Prolonged use may lead to copper deficiency and anaemia.
♦ It can be converted to the corrosive Zinc Chloride, and it is this
corrosive action that accounts for the acute toxicity of the soluble Zinc
salts.

Commercial Pack
Zedex® DS Syrup : 100 ml syrup in amber glass bottle. Each 5 ml
contains Zinc Sulphate Monohydrate USP equivalent to 10 mg of
elemental Zinc.

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