The Essentials

by Beauty Creations

Cosmetic actives for skin & hair care

Although all statements and information in this publication are believed to be accurate and reliable, they are presented gratis and for guidance only,
and risks and liability for results obtained by use of the products or application of the suggestions described are assumed by the user. THERE ARE NO
WARRANTIES OF ANY KIND. ALL EXPRESS AND IMPLIED WARRANTIES ARE DISCLAIMED. Statements or suggestions concerning possible use of the
products are made without representation or warranty that any such use is free of patent infringement and are not recommendations to infringe any patent.
The user should not assume that toxicity data and safety measures are indicated or that other measures may not be required. The claims and supporting
data provided in this publication have not been evaluated for compliance with any jurisdiction’s regulatory requirements and the results reported may
not be generally true under other conditions or in other matrices. Users must evaluate what claims and information are appropriate and comply with a
jurisdiction’s regulatory requirements. Recipient of this publication agrees to (i) indemnify and hold harmless each entity of the BASF organization for
any and all regulatory action arising from recipient’s use of any claims or information in this publication, including, but not limited to, use in advertising
and finished product label claims, and (ii) not present this publication as evidence of finished product claim substantiation to any regulatory authority.

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Beauty Creations
The Passion f or Beauty

Beauty Creations is the cosmetic active ingredient

business of BASF, resulting from the alliance of former entities
Beauty Care Solutions and Laboratoires Sérobiologiques.

Focusing on the skin and hair care market, Beauty Creations

develops and manufactures cosmetic active ingredients as well as
smart delivery system technologies especially designed to address
key correctives actions in skin and hair care categories.

In depth research in skin pigmentation, skin aging, protection against

environmental stress, modulation of hair growth, skin architecture as
well as unique R&D capabilities makes us today the partner of choice
for actively inspiring Beauty.

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Actives view

At the cornerstone of science

and people’s self-confidence,
beauty is the result of physical
change and emotion, tradition
and cultural perception. Through
the course of life, skin needs
specific care, which will protect
and maintain it at its best,
while at the same time keeping
the promise to enhance it and
hopefully fulfill our consumer’s
dreams.

For more than 60 years,

Beauty Creations has developed
its own expertise to combine
the best of skin science with
the cutting edge consumer
trends and develop cosmetic
actives able to efficiently not
only meet, but also anticipate
the consumer’s needs and
expectations.

In this catalog you will find a

broad and complete vision of
our active ingredients in skin,
scalp and hair care.

For further inquiries, such as

composition, efficacy, analytical
data, formulation processes or
regulation, please contact your
sales manager.

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Actives overview
Skin Skin Sensitive Face Body Skin Skin Hair growth Scalp
PRODUCT NAME surface perfection Moisturization skin architecture architecture defense color control care
Actiwhite™ •
AH-Care™ • • •
AMC Advanced Moisture Complex NP •
Arganyl ™
•
Asebiol ™ •
Beta-Hydroxyde ACSD ™
•
Betapur ™
•
Biophytex™ • •
CollGuard ™
•
Dermican™ •
DN-Age™ •
D-stria™
•
Elestab™ HP 100 •
Elestan ™
•
Eperuline ™
•
Freshaxyl ™ •
Generol ™ R •
Hyalufix™ • •
Hyaluronic Filling Spheres ™
• •
Hyalurosmooth ™
• •
Linefactor™ C • •
Lipofructyl ™ Argan •
Litchiderm ™
•
Lys’lastine™ v •
Marine Filling Spheres™ • •
Mariponics™ PSR •
Mat-XS Clinical
™
•
Melhydran ™
•
Myoxinol ™ •
Neurobiox™ • • •
Osmogeline™ • •
PatcH 2 O™ •
Phytokine™ • •
Phytolight™ BG •
Pilisoft ™
•
Proteasyl ™
• •
Puricare™ •
Purisoft ™
•
Relipidium™ •
Sanicapyl ™ •
Shadownyl ™
• •
Skinasensyl ™ •
Slim-Excess™ •
Sphingoceryl VEG ™
•
Sqisandryl ™ •
Symbiocell ™
•
Syniorage™ •
Trichogen™ VEG •
Tricholastyl ™
• •
Ultra Filling Spheres™ • •
Vegeseryl ™ HGP •
Vit-A-Like ™
•
5
X-pressin™ C • • •
SOLUBILITY W=Water / O=oils

1 Compliance of all the ingredients with Japanese

Standard of Quasi-Drug Ingredients (JSQI)

2 INCI name whether or not listed in «International

Cosmetic ingredient standard Chinese name»
(2007 version)

3 CAS number whether or not listed or exempted in

«IECSC 2010 (Inventory of Existing Chemical
Substances in China)»

4 Ecocert statements:
Approved: Raw material conform to Ecocert
standard of Natural and Organic
Cosmetics

Organic Certified: Raw material certified by Ecocert

Greenlife according to the Ecocert
Standard for Natural and Organic
Cosmetics available at
http://cosmetics.ecocert.com:
* 100% of the total ingredients are from Organic Farming
** 100% of the total ingredients are from natural origin,
50% of the total ingredients are from Organic Farming
*** 100% of the total ingredients are from natural origin,
82% of the total ingredients are from Organic Farming

5 INCI name whether or not listed in «Inventory of Existing

Chemicals in China 2012 (1st, 2nd and 3rd batch).

6 Cosmetic active dosage in clinical test formulations.

7 Suggested dose of use: in vitro data available only.

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Technical data summary
Asia Focus Ecocert5 Aspect Preservative System
Product information QD China IECSC EICIC Recommen-
Reference additive1 20072 20103 20124 Statement Liquid Powder None Phenoxyethanol Solubility ded use level 6
Actiwhite™ LS9860 • • • • Approved • • W 2%
AH-Care™ L65 • • • Approved • • W 10%
AMC Advanced Moisture Complex NP R11016 • • • • • W 5%
Arganyl ™ LS9781 • • • W 3%
Arganyl ™ LS9830 • Approved • • W 0.21%
Asebiol ™ LS9853 • • • • • W 5%
Beta-Hydroxyde™ ACSD G00011 • • • • • W 3%
Betapur™ A00067 • • • • • W 2%
Biophytex™ LS9832 • • • • W 3%
CollGuard ™ A00263 • • W (1 - 3%)7
Dermican™ LS9837 • • • W 0.9%
Dermican ™ LS9838 • • • W 0.9%
DN-Age™ LS9547 • • • • • W 3%
DN-Age™ LS9827 • • • Approved • • W 0.25%
D-stria™ A00259 • • • • • O 3%
Elestab™ HP 100 HP100 • • • • W 0.1%
Elestan™ LS9913 • • • W 3%
Elestan™ LS9879 • Organic certified** • • W 0.5%
Eperuline™ LS9627 • • Approved • • W 1%
Freshaxyl ™ LS9980 • • • • • O 0.4%
Generol ™ R Generol R • • • • • O (1 - 2%)7
Hyalufix™ A00102 • • • • W 3%
Hyaluronic Filling Spheres™ C00309 • • • • • O 2%
Hyalurosmooth™ LS8998 • • • • W 3%
Hyalurosmooth ™ LS8997 • • • • W 0.06%
Linefactor™ C A00314 • • • • W 3%
Lipofructyl ™ Argan LS9779 • • • Organic certified* • • O (1 - 5%)7
Litchiderm™ LS9704 • • • • W 5%
Lys’lastine™ v A00077 • • • • • W 1%
Marine Filling Spheres™ C00468 • • • • • O 1%
Mariponics™ PSR R11009 • • • • • W 3%
Mat-XS ™ Clinical A00098 • • • • W 2%
Melhydran™ LS9876 • • • • W 5%
Myoxinol ™ LS9736 • • • Approved • • W 1%
Neurobiox™ A00112 • • • • • • W 2%
Osmogeline™ R10979 • • • • • • W 10%
PatcH 2 O ™ A00297 • • • • • W 3%
Phytokine ™ A00287 • • • • • W 2.2%
Phytolight ™ BG A00043 • • • • • • W (1 - 4%)7
Pilisoft ™ LS9760 • • • W 1%
Proteasyl ™ LS9818 • • • • • W 3%
Proteasyl ™ LS8951 • • • Approved • • W 0.2%
Puricare™ LS9727 • • • • • W 2%
Purisoft ™ LS9726 • • • • • W 1.5%
Purisoft ™ LS9836 • • • Approved • • W 0.03%
Relipidium™ A00265 • • • • • W 3%
Sanicapyl ™ LS9863 • • W 1%
Shadownyl ™ R11026 • • • • • W 2%
Skinasensyl ™ LS9749 • • W 3%
Skinasensyl ™ LS9852 • • W 1%
Slim-Excess™ A00073 • • • W 3%
Sphingoceryl ™ VEG LS9948 • • • • • O 5%
Sqisandryl ™ LS9905 • • Organic certified* • • O 0.3%
Symbiocell ™ A00110 • • W 1%
Syniorage™ LS9847 • • W 1%
Trichogen™ VEG LS9922 • • • • W 10%
Tricholastyl ™ LS9912 • • • • W 10%
Ultra Filling Spheres™ C00487 • • • O (0.5 - 3%)7
Vegeseryl ™ HGP LS9874 • • • • W 10%
Vit-A-Like™ LS9793 • • W 5%
Vit-A-Like™ LS9898 • Approved • • W 0.4%
7
X-pressin™ C R11021 • • • • W 1%
Skin
surface
The surface of the skin is
by far the most approached
part of the daily beauty
routine. Indeed, there is
no need to wait for the
wrinkles to appear before
starting to talk about a
flawless high definition skin.
From the ages of 20 to 60
and beyond, we all wish to
have a perfectly smooth
skin.

Beauty Creations offers a

wide range of actives able
to resurface, lift and reduce
the appearance of these
first aging lines that our
customers do not want to
be accustomed to.

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Resurfacing
AH-Care™ Exfoliation with reduced stinging sensation and irritation.
Amphoteric Hydroxy Complex. Moisturization.
Visibly reduces the appearance of fine lines and enhances skin radiance.

Neurobiox™ Triple action on skin surface rejuvenation with comparable results to glycolic acid.
Achillea millefolium (yarrow) extract. Accelerates epidermal renewal in vitro.
Improves epidermal thickness.
Improves skin radiance in vivo.
Clinically proven to visibly reduce the appearance of wrinkles, pore size and soften
skin.

Syniorage™ Improvement of epidermal cohesion in vitro.

Synthetic tetrapeptide. Skin firmness and elasticity.
Refined skin texture for senior ranges.

Vit-A-Like™ Botanical alternative to retinol with high tolerance and stability.

Vigna aconitifolia seed extract. Stimulation of cellular renewal and collagen synthesis in vitro.
Clinically proven: anti-wrinkle efficacy.

X-pressin™ C Refreshes skin beauty.

Stabilized protease isolated from the latex Renews the skin’s youthful appearance.
Clinically proven to visibly smooth out, soften and enlighten the skin.
of Carica papaya.

Lifting
Vegeseryl™ HGP Anti-wrinkle / skin tightening effect.
High molecular weight soy native protein. Softening and soothing.
Improves skin elasticity and suppleness.

Anti-wrinkles
Hyalufix™ GL Activator of high molecular weight hyaluronic acid synthesis.
Alpinia Galanga extract. Wrinkles filling effect.
Clinically proven to visibly reduce the appearance of nasogenian fold.

Hyaluronic Filling Spheres™ Smoothing deep wrinkles.

Dehydrated hyaluronic acid microspheres. Long lasting hydration.

Linefactor™ C Protects FGF-2 in vitro.

Hibiscus Abelmoschus extract.
Stimulates collagen and GAG synthesis in vitro.
Redensifies dermis via stimulation of macromolecules synthesis (GAG, collagen) in vitro.
Stimules AQP-3 synthesis in vitro.
Clinically proven to visibly improve skin texture and elasticity and to reduce wrinkle
depth ( crow’s feet area).

Marine Filling Spheres™ Fills in wrinkles.

Dehydrated microspheres made of marine atelocollagen Long term hydration.
and marine chondroitin sulfate.
Myoxinol™ Antioxidant.
Hydrolyzed hibiscus esculentus proteins. Smoothes out expression lines.
Clinically proven: anti-wrinkle efficacy.

Neurobiox™ Triple action on skin surface rejuvenation with comparable results to glycolic acid.
Achillea millefolium (yarrow) extract. Accelerates epidermal renewal in vitro.
Improves epidermal thickness.
Improves skin radiance in vivo.
Clinically proven to visibly reduce the appearance of wrinkles, pore size and soften
skin.

Ultra Filling Spheres™ Enhanced water absorption and swelling capacity.

Dehydrated microspheres of hyaluronic acid Long-lasting moisturization.
Smoothing of fine lines and deep wrinkles.
and konjac glucomannans.
Shadownyl™ Stimulates the expression of Heme Oxygenase type-1 that catabolizes heme (red
An aqueous rockweed extract. pigment) degradation.
Strong antioxidant and anti inflammatory activities.
Clinically proven to visibly reduce the appearance of dark circles in 2 weeks and
wrinkles in 1 week only.

Vit-A-Like™ Botanical alternative to retinol with high tolerance and stability.

Vigna aconitifolia seed extract. Stimulation of cellular renewal and collagen synthesis in vitro.
Clinically proven: anti-wrinkle efficacy.

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Skin
perfection
The skin is a product of
one’s lifestyle. Under the
influence of hormones,
diet and stress it can have
unattractive irregularities
and lose its glow.

To correct and prevent

the skin from these
consequences, one can
exfoliate thickened skin,
purify epidermal florae and
neutralize the produced
sebum. These are some
examples of our actives
offer.

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Pore refiner
Beta-Hydroxyde™ ACSD Exfoliating activity.
Acacia polysaccharides and salicylic acid complex. Visibly refines pore size.
General perceivable improvement of oily skin while
keeping an optimal comfort (clinically proven).

Mat-XS™ Clinical Inhibits expression of 5a-reductase type 1 in vitro.

Synthetic sarcosine. Reduces the production of squalene in vitro.
Reduces visibly signs of oily skin in only 4 weeks.

Neurobiox™ Triple action on skin surface rejuvenation with comparable results to glycolic acid.
Achillea millefolium (yarrow) extract. Accelerates epidermal renewal in vitro.
Improves epidermal thickness.
Improves skin radiance in vivo.
Clinically proven to visibly reduce the appearance of wrinkles, pore size and soften skin.

X-pressin™ C Refreshes skin beauty.

Stabilized protease isolated from the latex Renews the skin’s youthful appearance.
Clinically proven to visibly smooth out, soften and enlighten the skin.
of Carica papaya.

Blemishes
AH-Care™ Exfoliation with reduced stinging sensation and irritation.
Amphoteric Hydroxy Complex. Moisturization.
Visibly reduces the appearance of fine lines and enhances skin radiance.

Biophytex™ Boosts microcirculation to improve evenness of skin tone.

Phyto-complex. Local soothing.
Anti-couperose - Anti-eye dark circles demonstrated benefits.

Oily skin
Mat-XS™ Clinical Inhibits expression of 5a-reductase type 1 in vitro.
Synthetic sarcosine. Reduces the production of squalene in vitro.
Reduces visibly signs of oily skin in only 4 weeks.

Purifying
Betapur™ Regulates and balances the skin bacterial flora through
Peumus boldus (Boldo) leaf extract. activation of b-defensins synthesis in vitro.
Visibly reduces pore size and appearance of oily skin.
Visibly reduces the imperfections of acne prone skin (clinical test).

Freshaxyl™ Bacteriostatic efficacy.

Combination of moringa extract and glyceryl laurate. Clinically proven to reduce the odor caused by perspiration.
As good as triclosan.

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Moisturization
Like the body itself, the skin
requires nourishment and
hydration. We give it water,
trace elements, vitamins,
micro-nutrients and we coat
it with plant-based milks for
health - and, of course, for
beauty.

Our expertise allows the

skin to be nourished and
hydrated instantly or long
term, acting on the different
targets such as skin barrier
improvement and physical
protection.

Sensitive skin
Having a sensitive skin is
certainly one of the most
common conditions of the
skin and one of the most
difficult to measure and
evaluate from a clinical
point of view. The skin feels
uncomfortable and inflamed
due to stinging, acne,
burning or allergies.
It is often a matter of
threshold, that one needs
to slightly modulate to
reduce the sensation of
pain. Our cosmetic actives
will support you to achieve
that aim.

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Moisturization
AMC Advanced Moisture Complex NP
Complex of hygroscopic molecules/hydrating agents.
Intense moisturizing complex with water binding properties.
Strengthens skin barrier.
Immediate and long term moisturization superior than hyaluronic acid (in vivo study).

Generol™ R Moisturization for dry and mature skin.

Rapeseed phytosterols. Anti-inflammatory.
Skin barrier strengthening.

Hyalurosmooth™* Botanical alternative to hyaluronic acid (derivatives).

Cassia Angustifolia Seed Polysaccharide. Skin moisturization (compared to sodium hyaluronate as benchmark).
Enhances the smoothness and softness of the skin.
*This product does not contain hyaluronic acid (derivatives).
Improves skin radiance (clinically proven).

Lipofructyl™ Argan Skin softness.

Organic Argan oil. Moisturization.
Nail care.

Melhydran™ NMF-like activity in vitro.

Honey extract. Moisturization.
Visibly improves skin microrelief and diminishes skin roughness.
Osmogeline™ Reinforces skin barrier via stimulation of involucrin and ceramides synthesis in vitro.
Red seaweed extract. Protects the skin : anti-MMP - antioxidant in vitro.
Demonstrated benefits: visibly moisturizes and smoothes skin surface within 3 days.
Skin looks more radiant and luminous.

PatcH 2O™ Instant relief - Increases skin hydration after 30 min of application (in vivo).
Sustained protection - Up to 48 hours of hydration even after just one application (in vivo).
Molecular patch carrying highly concentrated Optimized moisturization capital - Prolongs skin hydration up to 5 days after application
hydrating substances. (in vivo).

Relipidium™ Stimulates the synthesis of lipids from the inside (in vitro).
Yeast extract modified by biotechnology. Repairs and reinforces the cutaneous barrier.
In vivo visible relipiding effect - Long lasting moisturization.
Sphingoceryl™ VEG Skin barrier strengthening.
Sunflower phyto-ceramides. Improves skin comfort.
Structuring and repair of the skin microrelief.

Sensitive skin
Skinasensyl™ Increase of the skin tolerance threshold.
Synthetic tetrapeptide. Clinically proven: reduction of sensations of pain and discomfort.

Symbiocell™ Pro-tolerance cosmetic ingredient for sensitive skin.

Cestrum latifolium leaf extract. Regulates dendritic cells activity in vitro.
Restores skin comfort.
Anti-redness efficacy.

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Face
architecture
All the attention you can
give to your skin will be
useless if you do not
protect and maintain its
architecture properly. Like a
flower without strong stake,
the skin will collapse and
wrinkles will appear.

In the aim to restoring a

youthful looking face but
preserving one’s identity,
our cosmetic actives will
make the skin firmer and
reshape its volume.

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Instant filler
Marine Filling Spheres™ Fills in wrinkles.
Dehydrated microspheres made of marine atelocollagen Long term hydration.
and marine chondroitin sulfate.
Hyaluronic Filling Spheres™ Smoothing deep wrinkles.
Dehydrated hyaluronic acid microspheres. Long lasting hydration.

Ultra Filling Spheres™ Enhanced water absorption and swelling capacity.

Dehydrated microspheres of hyaluronic acid Long-lasting moisturization.
Smoothing of fine lines and deep wrinkles.
and konjac glucomannans.

Firming
Dermican™ Targeted action on dermis structure via stimulation of lumican and collagen synthesis in vitro.
Synthetic tetrapeptide. Global restructuring of skin matrix.
Clinically proven: improvement of skin thickness and firmness.

Elestan™* Anti-glycation activity in vitro on Collagen and Elastin.

Manilkara multinervis leaf extract. Stimulates the GAGs synthesis (ex vivo).
Clinically proven: skin tonifying effect and visible reduction of strech marks.
* cosmetic active ingredient

Eperuline™ Unique target: Inflammaging.

Eperua falcata bark extract. Fights against age-related chronic micro-inflammation.
Visible effects on improvement of skin firmness & elasticity.

Linefactor™ C Protects FGF-2 in vitro.

Hibiscus Abelmoschus extract.
Stimulates collagen and GAG synthesis in vitro.
Redensifies dermis via stimulation of macromolecules synthesis (GAG, collagen) in vitro.
Stimules AQP-3 synthesis in vitro.
Clinically proven to visibly improve skin texture and elasticity and to reduce wrinkle depth ( crow’s feet
area).

Phytokine™ Restores cell renewal mechanisms.

Soy extract modified by biotechnology. Activates the synthesis of ECM components: collagen and GAGs in vitro.
Restructuring, regenerating and firming action.
Increase the epidermal thickness.

Proteasyl™ Stimulation of collagens, GAGs and elastin synthesis in vitro.

Pea polypeptides. Anti-elastase in vitro.
DEJ stabilization; stimulation of Perlecan synthesis.
Epidermis reinforcement: stimulation of Syncedan-1 synthesis.
Improvement of skin elasticity and firmness (clinical demonstration).

Sqisandryl™ Exclusive focus on the DEJ: via stimulation of Collagen-17 and ladinin-1 synthesis.
Schisandra chinensis berries extract. Strengthens the dynamic cohesion between the dermis and the epidermis ex vivo.
Clinically proven to increase the skin resilience, elasticity and firmness.

Volumizing
Dermican™ Targeted action on dermis structure via stimulation of lumican and collagen synthesis in vitro.
Synthetic tetrapeptide. Global restructuring of skin matrix.
Clinically proven: improvement of skin thickness and firmness.

Hyalufix™ GL Activator of high molecular weight hyaluronic acid synthesis.

Alpinia Galanga extract. Wrinkles filling effect.
Clinically proven to visibly reduce the appearance of nasogenian fold.

Proteasyl™ Stimulation of collagens, GAGs and elastin synthesis in vitro.

Pea polypeptides. Anti-elastase in vitro.
DEJ stabilization; stimulation of Perlecan synthesis.
Epidermis reinforcement: stimulation of Syncedan-1 synthesis.
Improvement of skin elasticity and firmness (clinical demonstration).

3D Effect
Elestan™* Anti-glycation activity in vitro on Collagen and Elastin.
Manilkara multinervis leaf extract. Stimulates the GAGs synthesis (ex vivo).
Clinically proven: skin tonifying effect and visible reduction of strech marks.
* cosmetic active ingredient

Hyalufix™ GL Activator of high molecular weight hyaluronic acid synthesis.

Alpinia Galanga extract. Wrinkles filling effect.
Clinically proven to visibly reduce the appearance of nasogenian fold.

Lys’lastine™ v Stimulates LOXL synthesis in vitro.

Anethum Graveolens extract. Renews elastin functionality in vitro.
Clinically proven to visibly reactivate skin resilience, reshape face contour and smooth expression lines.

15
Body
architecture
Much like the face, the
skin of the body undergoes
numerous outbreaks and
damages due to hormonal
changes and ageing. How
to keep it smooth and
beautiful?

Our knowledge of skin

biology allows us to shape
the body, make it firmer and
reduce the appearance of
stretch-marks.

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Body shaping
Slim-Excess™ New biological targets in slimming: spermine and spermidine to block the
Sulfo-carrabiose from red seaweed hydrolyzate. polyamines.
Inhibits Lipogenesis - activates Lipolysis and adipocyte differenciation in vitro.
Clinically proven: visible slimming action.

Anti-stretch marks
D-stria™ Reduces the tension of the striae-myofibroblasts in vitro.
Saw palmetto extract. Stimulates elastin and collagen synthesis in vitro.
Clinically proven to visibly reduce the appearance of stretch marks.

Elestan™* Anti-glycation activity in vitro on Collagen and Elastin.

Manilkara multinervis leaf extract. Stimulates the GAGs synthesis (ex vivo).
Clinically proven: skin tonifying effect and visible reduction of strech marks.
* cosmetic active ingredient

Firming
Phytokine™ Restores cell renewal mechanisms in vitro.
Soy extract modified by biotechnology. Activates the synthesis of ECM components: collagen and GAGs in vitro or ex vivo.
Restructuring, regenerating and firming action.
Increase the epidermal thickness.

Proteasyl™ Stimulation of collagens, GAGs and elastin synthesis in vitro.

Pea polypeptides. Anti-elastase in vitro.
Improvement of skin elasticity and firmness (clinical demonstration).

17
Skin
defense
The first step in beauty care
is protection. The skin is
constantly being attacked
from in- and outside.
Therefore, protection needs
to be considered before
starting the correction
process.

Skin must be shielded from

aging accelerators such
as enzyme degradation,
UV rays, glycation and
pollution, to name the
most common ones. The
cosmetic actives we have
created serve this purpose.

18
Glycation
CollGuard™ Protects and stimulates skin collagen network in vitro.
Davilla Rugosa leaf extract. Anti glycation - Anti MMP - Anti-Free radicals in vitro.
Promotes functional collagen neo-synthesis in vitro.

Matrix protection
Arganyl™ Anti-MMP in vitro.
Argan leaf polyphenols. Anti-collagenase in vitro.
Improves skin firmness.
Clinical study: protection against UVR-induced ROS.
CollGuard™ Protects and stimulates skin collagen network in vitro.
Davilla Rugosa leaf extract. Anti glycation - Anti MMP - Anti-Free radicals in vitro.
Promotes functional collagen neo-synthesis in vitro.
Litchiderm™ Free radical scavenger.
Lychee extract. Moisturizing.
Enhancement of skin complexion.
Osmogeline™ Reinforces skin barrier via stimulation of involucrin and ceramides synthesis
Red seaweed extract. in vitro.
Protects the skin : anti-MMP - antioxidant in vitro.
Demonstrated benefits: visibly moisturizes and smoothes skin surface within
3 days.
Skin looks more radiant and luminous.

Protection
DN-Age™ Protection for global skin rejuvenation.
Candle tree leaf extract with identified tracer. Support for the natural DNA repair system in vitro.
Clinically proven to prevent visibly skin photo-aging.
Osmogeline™ Reinforces skin barrier via stimulation of involucrin and ceramides synthesis
Red seaweed extract. in vitro.
Protects the skin : anti-MMP - antioxidant in vitro.
Demonstrated benefits: visibly moisturizes and smoothes skin surface within
3 days.
Skin looks more radiant and luminous.

Anti-pollution
Mariponics™ PSR Prevention of and protection against skin pollution.
Algae extract and yeast extract. Counter-regulates the effects of air pollutants.
Clinically proven: skin smoothing effect (wrinkles and pores).
Improvement of skin conditions and appearance.
Purisoft™ Anti-pollution.
Moringa oleifera proteins. Clinically proven: Skin purification - Cleansing enhancer.
Enhances skin complexion and healthy glow.

Sun care
DN-Age™ Protection for global skin rejuvenation.
Candle tree leaf extract with identified tracer. Support for the natural DNA repair system in vitro.
Clinically proven to prevent visibly skin photo-aging.

19
Skin color
The coloration and
discoloration of the
skin, whether linked
to extrinsic or intrinsic
factors, is deceptive
when not controlled.
Asian consumers want a
whiter skin, while Western
consumers are looking for
more radiant skin with no
age spots.

Whether you need

whitening, radiance or
homogeneous complexion,
Beauty Creations is able to
provide you with the right
cosmetic active.

20
Brightening
Actiwhite™ Asia focus skin lightening agent.
Synergistic complex. Clinical efficacy comparable to the one of the best market benchmark.
Demonstrated anti age spots activity in vivo.
Phytolight™ BG Powerful inhibitor of tyrosinase activity (in vitro).
Botanical complex. Asia focus skin brightening agent.

Radiance
AH-Care™ Exfoliation with reduced stinging sensation and irritation.
Amphoteric Hydroxy Complex. Moisturization.
Visibly reduces the appearance of fine lines and enhances skin radiance.

Hyalurosmooth™* Botanical alternative to hyaluronic acid (derivatives).

Cassia Angustifolia Seed Polysaccharide. Skin moisturization (compared to sodium hyaluronate as benchmark).
Enhances the smoothness and softness of the skin.
*This product does not contain hyaluronic acid (derivatives).
Improves skin radiance.

Neurobiox™ Triple action on skin surface rejuvenation with comparable results to glycolic acid.
Achillea millefolium (yarrow) extract. Accelerates epidermal renewal in vitro.
Improves epidermal thickness.
Improves skin radiance in vivo.
Clinically proven to visibly reduce the appearance of wrinkles, pore size and soften
skin.

X-pressin™ C Refreshes skin beauty.

Stabilized protease isolated from the latex Renews the skin’s youthful appearance.
Clinically proven to visibly smooth out, soften and enlighten the skin.
of Carica papaya.

Reduction of dark circles

Shadownyl™ Stimulates the expression of Heme Oxygenase type-1 that catabolizes heme (red
An aqueous rockweed extract. pigment) degradation.
Strong antioxidant and anti inflammatory activities.
Clinically proven to visibly reduce the appearance of dark circles in 2 weeks and
wrinkles in 1 week only.

Biophytex™ Boosts microcirculation to improve evenness of skin tone.

Phyto-complex. Local soothing.
Anti-couperose - Anti-eye dark circles demonstrated benefits.

21
Hair growth
control &
Scalp care
The hair reflects people’s
inner balance, health and
lifestyle. Hair is influenced
by all the hazards that can
come from living in our
environment (pollution,
chemical products, UV ray,
etc.). Therefore, it needs
proper care as much as
skin does and needs to be
protected, nourished and
managed daily. Everyone
wishes to have shiny, silky
smooth hair and a healthy
scalp.

To support you in having a

healthy scalp and healthy
looking hair, hereafter you
will find our solutions.

22
Hair growth control
Pilisoft™ Effective solution to visibly prolong and enhance the benefits of hair removal
Gymnema sylvestre leaf extract. treatments.
In vitro hair growth reducer: demonstrated benefits.
Improved aesthetics and easier shaving.
Trichogen™ VEG A global treatment as alternative to hair restoration procedures (clinically proven).
Phyto-synthetic complex. Improvement of hair strength.

Tricholastyl™ Anti-age concept for scalp.

Phyto-complex based on an Indian plant. Protection of hair youthfulness.
Improved hair thickness.

Healthy scalp
Asebiol™ Clinically proven to visibly reduce the apearance of the oiliness and imperfections
Synergistic complex. of the skin.
Inhibition of 5a-reductase.
Reduction of scalp oiliness.
Elestab™ HP 100 Significant reduction of dandruff.
Hexamidine diisethionate. Decrease of scalp itching and hair regreasing.
Visible continuing effect after end of treatment.
Sanicapyl™ Hair beauty appearance and feeling booster.
Natural complex. Reduction of scalp oiliness. 
Clinical efficacy on dandruff reduction comparable to market benchmark.
Tricholastyl™ Anti-age concept for scalp.
Phyto-complex based on an Indian plant. Protection of hair youthfulness.
Improved hair thickness.

Anti-pollution
Puricare™ Hair protection against environmental stresses.
Moringa oleifera proteins. Anti-pollution demonstrated efficacy.
«Anti-greasy» effect for oily hair.

23
Techno view

Technology is a very effective

way to modify the behavior of
a cosmetic active ingredient,
which, when applied alone to
the skin, acts according to its
physical and chemical properties.

In this offering we present the full

range of possibilities that Beauty
Creations can offer to you.

You will discover how to tailor

your formulas by creating
stabilized active cosmetic
ingredients, which will then act
at the required space and time
to maximize its effectiveness and
stability.

24
Treating the skin where needed
Target dry areas
Skin that is dry on the surface has particular characteristics: corneocytes are disorganized and clustered in scaly patches.
Keratin is also negatively charged, and this area can be targeted using positively charged elements.

Target in over areas

The dermal cells create skin firmness. Further down in the skin are the adipocytes, which are involved in slimming
and liposculpture. The technologies allow for penetration to convey active ingredients, intact, to their targets. These
technologies are designed for cosmetic active ingredients that either do not penetrate well or are subject to deterioration
when penetrating the skin.

Treating the skin when needed

Prolong the duration of action on the skin
The application of a free active ingredient produces a high concentration at the moment of application, but it rapidly
diminishes and becomes less effective. The use of delivery systems overcomes this problem by maintaining an effective
level of concentration for a longer period of time and thus intensifying the efficacy of the active cosmetic ingredients.

React only when expose to UV

The tendency is toward the universal use of UV protection, even beyond sun care products. High SPFs are present in
daily skin and hair care products. This chronic use of UV filters can cause irritation and sensitization in the long term. In
response, we have developed an smart technology that reacts when expose to UV to release the cosmetic active.

Stabilize your active ingredients

Co-encapsulate with a protective agent
Anti-oxidants are used across the board in cosmetics. Each anti-oxidant exerts a specific action on a category of ingredients,
lipidic, hydrophilic, etc. The concentration of anti-oxidants is also important in the stabilizing process. For this reason, when
developing active cosmetic ingredient stabilization systems, we isolate the unstable active cosmetic ingredient within the
core of a vector in order to prevent alterations linked to interaction with the formula. We also put a protective agent in the
vector to ensure the maximum protection of the active cosmetic ingredient in the formulation.

Distribute molecules within the vector

Some molecules must be used at relatively low concentrations because going beyond these limits can lead to crystallization
(as in the case of caffeine and ursolic acid). To overcome this problem, the concentration of the active cosmetic ingredient
must be artificially reduced. Here again, technologies offer the solution.

Soften your active ingredients

Improve the kinetics of release on skin
The application of a free active cosmetic ingredient produces a high concentration that can cause irritation. The use of
delivery systems limits the problem and maintains lower concentrations over a longer period. The efficacy is sustained and
the potential for irritation is reduced.

Make your formulas more appealing

Microspheres are attractive and effective. They can encapsulate rare oils, essential minerals or vitamins to embellish the
skin’s surface.

25
Techno overview
Main Visible/
Product Description property Invisible Technology Pa
(encaps)

Catiosphere™ Positively charged marine microspheres composed of marine collagen and chitosan. The positive
Positively charged charge is obtained by encapsulating quaternized honey which is then oriented toward the surface
microspheres of the sphere. Interfacial
When Catiosphere™ contacts the skin, it binds preferentially to damaged zones, where the Targets dry zones Invisible polymerization
repairing active cosmetic ingredients are progressively released.
This vector is used to preferentially encapsulate hydrophilic active substances.

Cylasphere™
Microspheres specific
for fragile actives
Plant microspheres composed of acacia and alginate. The size range of Cylasphere™ is between
5 and 50 µm. They release active cosmetic substances by the action of skin enzymes.
Degradation is gradual. In this way, release of the active cosmetic substance is progressive, Protects fragile
which can be referred to as “bio-delivery”. Invisible Transacylation
oily actives
Cylasphere™ can be used to encapsulate liposoluble active substances and is especially indicated
for fragile active cosmetic ingredients.

Cytovector™ Positively charged plant liposomes composed by soy lecithin and quaternized soy proteins.
Cationic liposomes These cationic molecules help to increase the cell bioavailability.
From a diameter between 150 and 300 nm, Cytovector™ particules can encapsulate both Enhances Invisible Emulsion
hydrophilic and lipophilic cosmetic ingredients. It has a broad range of cosmetic applications: cell delivery
lightening, protecting, slimming, hydrating...

Micropatch™ (marine) A meshwork of marine macromolecules that leads to the sustained release of active cosmetic
Molecular network substances. The combination of marine collagen and alginate creates an organized network in
of hydrophilic which small active cosmetic substances can be introduced. Micropatch™ Marine stays on the
macromolecules surface of the skin, forming a “second skin”, from which active cosmetic substances are slowly Lengthens the time Molecular
released by a shift in the osmotic equilibrium. of action on the skin
- association
We have shown that the use of Micropatch™ Marine prolongs the efficacy time of active cosmetic
substances.
Micropatch™ Marine can contain hydrophilic active substances.

Micropatch™ (vegetal) A meshwork of plant macromolecules for the sustained release of active cosmetic substances.
Molecular network The combination of acacia proteins and alginate creates an organized network in which small
of hydrophilic active cosmetic substances can be introduced. Micropatch™ Vegetal stays on the surface of the
macromolecules skin, forming a “second skin”, from which active cosmetic substances are slowly released by a Lengthens the time Molecular
shift in the osmotic equilibrium. of action on the skin
- association
We have shown that the use of Micropatch™ Vegetal prolongs the efficacy time of active cosmetic
substances.
Micropatch™ Vegetal can contain hydrophilic active substances.

Phytosphere™
Vegetal microspheres
Plant microspheres composed of carob, wheat or acacia. Phytosphere™ can be prepared in a
Protects,
wide range of sizes. When smaller than 100 µm (50 to 80 µm), they release active cosmetic Visible
substances by the action of skin enzymes. embellishes
Degradation is gradual because of the size range of the spheres. The smallest are tightly cross-
linked and are the most resistant to enzymatic degradation, while the largest open more rapidly. Interfacial
In this way, release of the active cosmetic substance is progressive, which can be referred to as Stabilize polymerization
“bio-delivery”. cosmetic actives, Invisible
Phytosphere™ can be used to encapsulate all types of active cosmetic substances, water-soluble, lengthens action
fat-soluble and insoluble. on the skin

Smartvector™ UV Microcapsules of marine DNA sensitive to UV irradiation. When applied to the skin, the release of
DNA microspheres protective active cosmetic substances is triggered by UVA or UVB radiation. The microcapsules
are smaller than 100 µm and provide a homogeneous surface cover. Delivers actives Interfacial
Smarvector™ UV can be used to encapsulate lipophilic active cosmetic substances, chemical in presence Invisible polymerization
sunscreens or antioxidants. The plant version and the version to be used with water-soluble of UV light
active cosmetic substances are under development.

Stabilized Liposome
Liposome stabilized
with collagen,
glycosaminoglycans
Plant liposomes composed of soy lecithin surrounded by a matrix of marine collagen and
glycosaminoglycans. The surrounding layer has a stabilizing function and reinforces the
phospholipid bi-layers, preventing their deterioration until the active cosmetic ingredient is Enhances active
cosmetic ingredient
needed. Liposome Stabilized, as classical liposomes, favor the protection of cosmetic active Invisible Emulsion
substances as a result of their protective capacity. delivery where it is
Of moderate size, 200 to 700 nm, Liposome Stabilized can be used to encapsulate lipophilic and needed
hydrophilic active substances.

Thalasphere™ Microspheres composed of marine collagen and glycosaminoglycans. Thalasphere™ can be

Marine microspheres
Protects,
prepared in a wide range of sizes. When smaller than 100 µm (50 to 80 µm), these vectors Visible
release active cosmetic substances by the action of skin enzymes. Degradation is gradual embellishes
because of the size range of the spheres.
The smallest are tightly cross-linked and are the most resistant to enzymatic degradation, Interfacial
while the largest open more rapidly. In this way, release of the active cosmetic substance is Stabilize polymerization
progressive, which can be referred to as “bio-delivery”. cosmetic actives, Invisible
Thalasphere™ can be used to encapsulate all types of active cosmetic substances, hydrosoluble, lengthens action
liposoluble and insoluble. on the skin

Encapsulation * the efficient active concentration is lowered when used in technologies

Molecular coupling /  a ssociation

26
 Membrane Biodelivery Active ingredient Max concentration
y Patent Regulation Origin (encapsulation) system Size (nature and max encapsulation rate) in finished product (5%)*
duration

l Collagen, GAGs, Water-soluble Water-soluble

ion Yes Europe/Asie/US Marine Medium 10-80 μm / / / /
quaternized honey 2% O.O5%

on Water-soluble Oil-soluble Insoluble Water-soluble Oil-soluble Insoluble

Yes Europe/Asie/US Plant Alginate, acacia Medium 5-50 μm / 100% / / 0.5% /

Water-soluble Oil-soluble
Europe/Asie/US Soy lecithin / Water-soluble Oil-soluble Insoluble Insoluble
Yes Plant Short 100-400 nm (lecithin 5%) (lecithin 5%)
non QD quaternized protein Up to 50% 0.5% / /
2.5% 0.025%

r Water-soluble Oil-soluble Insoluble Water-soluble Oil-soluble Insoluble

Yes Europe/Asie/US Marine Collagen, alginate Long /
n 30% / / 1.5% / /

r Water-soluble Oil-soluble Insoluble Water-soluble Oil-soluble Insoluble

- Europe/Asie/US Plant Acacia, alginate Long /
n 30% / / 1.5% / /

Water-soluble Oil-soluble Insoluble Water-soluble Oil-soluble Insoluble

Plant Carob (all sizes) Short 100-1000 μm 20% 40% 20% 0.1% 0.2% 0.1%

l
ion Yes Europe/Asie/US
Wheat, Water-soluble Oil-soluble Insoluble Water-soluble Oil-soluble Insoluble
Plant Medium 10-90 μm
acacia (invisible) 20% 100% 5% 0.1% 0.5% 0.025%

Water-soluble
l Yes Europe/Asie/US Marine DNA No sensitivity 10-90 μm development Oil-soluble Insoluble Water-soluble Oil-soluble Insoluble
ion to enzymes pending 100% / / 0.5% /

Water-soluble Oil-soluble
Plant/ Soy lecithin / Water-soluble Oil-soluble Insoluble Insoluble
Yes Europe/Asie/US Short 200-700 nm (lecithin 3%) (lecithin 3%)
marine Collagen, GAGs 50% 10% / /
0.075% 0.015%

Water-soluble Oil-soluble Insoluble Water-soluble Oil-soluble Insoluble

Short 100-1000 μm 20% 40% 20% 0.1% 0.2% 0.1%

l Yes Europe/Asie/US Marine Collagen / GAGs

ion
Water-soluble Oil-soluble Insoluble Water-soluble Oil-soluble Insoluble
Medium 10-90 μm 20% 100% 5% 0.1% 0.5% 0.025%

27
For more contact please contact: EUROPE
BASF Beauty Creations
49, avenue Georges Pompidou
92593 Levallois-Perret Cedex
France
Tel: +33 (0) 1 49 64 53 97
Fax: +33 (0) 1 49 64 53 85
March 13, 2013
Japan & Asia-Pacific
BASF Japan Ltd.
21F Roppongi Hills Mori Tower,
6-10-1 Roppongi, Minato-ku,
Tokyo, 106-6121 Japan
Tel: +81 (0) 3-3796-9214
Fax: +81 (0) 3-3796-9299
Americas
BASF Corporation
361 Sheep Pasture Road
East Setauket, NY 11733
USA
Tel: +1 631-380-2652