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Dosage Calculations

Adult and Pediatric Dosages Based on


Body Weight

With Rhonda Lawes

Kenneth Sy, kennnethsy@gmail.com


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Safety First!
Finding a safe dose for patients often requires
calculating doses based on body weight.

Neonates Adults: Doses may be


and infants: calculated in:

Usually weighed Pounds or kg mcg or mg per


in kilogram kg, lb or day

The total daily dose may be divided into


more than one individual dose.

Kenneth Sy, kennnethsy@gmail.com


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How to Convert lb to kg

There are 2.2 lbs in 1 kg.

2.2 lbs
When you are converting kg When you are converting
to pounds the number of pounds to kg the number of
pounds will be higher than kg. kg will be smaller than lbs.
1 kg

Kenneth Sy, kennnethsy@gmail.com


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Mr. Burton weighs 198 lbs. How many kg does
Mr. Burton weigh?*

*When you are converting pounds to kg the number of kg will be smaller than lbs.

2.2 lbs = 1 kg

Divide 198 by 2.2 to find the correct number of kg.

 198 lbs / 2.2 = 90 kg

Kenneth Sy, kennnethsy@gmail.com


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ordered a medication dosage that requires pounds.

*When you are converting kg to pounds the number of pounds will be higher than kg!

2.2 lbs = 1 kg

Multiply 75.3 kg by 2.2 to find the correct number of


pounds.

 75.3 kg x 2.2 = 165.66 lbs


Kenneth Sy, kennnethsy@gmail.com
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Fractions to Decimals

¼ = 0.25
½ = 0.50
¾ = 0.75

Kenneth Sy, kennnethsy@gmail.com


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Your Turn to Practice!

• Convert pounds to kilograms and


kilograms to pounds.

• Complete the 10 practice problems


in your downloadable material and
check your answers.

Kenneth Sy, kennnethsy@gmail.com


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Usual dose: Children, 20 40 mg per kg a day in 75 mL (when mixed)
three divided doses. Adults, 250 mg three times a
day. See literature. Contains Cefaclor-Monohydrate
equivalent to 3.75 g anhydrous Cefaclor in a dry
pleasantly flavored mixture. LAWES
Prior to mixing: Add 45 mL of water in two portions
to the dry mixture in the bottle. Shake well after each
addition. BugAway
Each 5 mL (approx. one teaspoonful) will then For oral suspension
contain: Cefaclor-Monohydrat equivalent 250 mg
anhydrous Cefaclor.
USP
SHAKE WELL BEFORE USING
Oversize bottle provides extra space for shaking. 250 mg
Store in a refrigerator. May be kept for 14 days per 5 mL
without significant loss of potency. Keep tightly CAUTION: Federal (U.S.A.) law prohibits
closed. Discard unused portion after 14 days. dispensing without prescription
Lawes & Co., Lecturio, LPZ
Kenneth Sy, kennnethsy@gmail.com
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Pediatric Oral Liquid Medications

Usual dose: Children, 20 40 mg


per kg a day in three divided
• Pediatric oral liquid medications will doses. Adults, 250 mg three
usually provide a safe range of times a day. See literature.
medication the child can receive in Contains Cefaclor Monohydrate
a 24 hour period based on weight. equivalent to 3.75 g anhydrous
Cefaclor in a dry pleasantly
flavored mixture.
• For example: 20 40 mg/kg/day
in divided doses every 8 hours

Kenneth Sy, kennnethsy@gmail.com


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Pediatric Oral Liquid Medications
The label states: 20 40 mg/kg/day in divided doses every 8 hours

How to figure the safe and therapeutic range for a 10 kg child:

10 x 20 = 200 mg 10 x 40 = 400 mg
(lowest therapeutic dose) (highest safe range of medication)

 If a child weighed 10 kg this range would be (200 400 mg/day)

Kenneth Sy, kennnethsy@gmail.com


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Pediatric Oral Liquid Medications
The label states: 20 40 mg/kg/day in divided doses every 8 hours

If a child weighed 10 kg the safe range would be (200 400 mg/day).

1 day = 24 hours 3 doses in a day = 24/8


which is one dose every 8 hours

The order reads give 125 mg every 8 hours. Is this safe?

Kenneth Sy, kennnethsy@gmail.com


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Pediatric Oral Liquid Medications
The label states: 20 40 mg/kg/day in divided doses every 8 hours

If a child weighed 10 kg the safe range would be (200 400 mg/day).

125 mg x 3 (doses q 8 hours) = 375 mg in one day (24 hours)

The order reads give 125 mg every 8 hours. Is this safe?

Kenneth Sy, kennnethsy@gmail.com


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Pediatric Oral Liquid Medications
The label states: 20 40 mg/kg/day in divided doses every 8 hours

If a child weighed 10 kg the safe range would be (200 400 mg/day).

200 mg x 3 (doses q 8 hours) = 600 mg in one day (24 hours)

What if the order read give 200 mg every 8 hours is this safe?

Kenneth Sy, kennnethsy@gmail.com


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Safety Your Responsibility

When a medication is ordered in divided


doses make sure the total daily dose is within
the stated safe therapeutic range on the label.

Kenneth Sy, kennnethsy@gmail.com


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Usual dose: Children, 50 mg per kg a day in equally 75 mL (when mixed)
divided doses at 6 hour intervals. Adults, 250 mg
three times a day. See literature. Contains Cefaclor-
Monohydrate equivalent to 3.75 g anhydrous Cefaclor
in a dry pleasantly flavored mixture. LAWES
Prior to mixing: Add 45 mL of water in two portions
to the dry mixture in the bottle. Shake well after each
addition. CoughNot
Each 5 mL (approx. one teaspoonful) will then For oral suspension
contain: Cefaclor-Monohydrat equivalent 250 mg
anhydrous Cefaclor.
USP
SHAKE WELL BEFORE USING
Oversize bottle provides extra space for shaking. 250 mg
Store in a refrigerator. May be kept for 14 days per 5 mL
without significant loss of potency. Keep tightly CAUTION: Federal (U.S.A.) law prohibits
closed. Discard unused portion after 14 days. dispensing without prescription
Lawes & Co., Lecturio, LPZ
Kenneth Sy, kennnethsy@gmail.com
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250 mg CoughNot PO q 6 hours

LAWES

a 20 kg child for one day? CoughNot
For oral suspension
• How many doses will be given in one day?
USP
• The order reads 250 mg CoughNot
PO q 6 hours. Is this safe?
250 mg
per 5 mL
• Does the healthcare provider need to be Children, 50 mg/kg a day
consulted? in equally divided doses at
6 hour intervals

Kenneth Sy, kennnethsy@gmail.com


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250 mg CoughNot PO q 6 hours
dosage
for a 20 kg child for one day? LAWES
• The label states 50 mg/kg is the usual dose.
CoughNot
 20 x 50 = 1,000 mg/day For oral suspension
USP
How many doses will be given in one day?
250 mg
per 5 mL
• 24 hrs / 6 hrs = 4 doses in 24 hours
Children, 50 mg/kg a day
in equally divided doses at
6 hour intervals

Kenneth Sy, kennnethsy@gmail.com


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250 mg CoughNot PO q 6 hours
The order reads 250 mg CoughNot
PO q 6 hours. Is this safe? LAWES
• 4 doses x 250 mg = 1,000 mg/24 hours
CoughNot
 Yes, this is within the safe range. For oral suspension
USP
Does the healthcare provider need
to be consulted? 250 mg
per 5 mL
• No, because this dosage is safe.
Children, 50 mg/kg a day
in equally divided doses at
6 hour intervals

Kenneth Sy, kennnethsy@gmail.com


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Weight Based Dosage with Conversion
Susie Que is a 10-year-old female who weighs
88 pounds. The Healthcare Provider (HCP) orders
CoughNot 500 mg every 6 hours.
Is this a safe dose for this particular child?

Convert first:
88 lbs / 2.2 = 40 kilograms

Calculate the safe range:


40 kg x 50 mg = 2,000 mg of CoughNot

CoughNot is 500 mg every 6 hours:


4 doses (24 hours / 6 hours)(500 mg every 6 hours) x (4 doses in 24 hours)
4 x 500 mg = 2,000 mg of CoughNot= 2,000 mg total
Kenneth Sy, kennnethsy@gmail.com
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Practice Problems

the following:
• Reading labels to determine safe
therapeutic range
• Calculating dosages based on weight
in pounds or kilograms
• Calculating the total daily dose from
the divided dose

Complete the practice problems in your


downloadable material and check your
answers!

Kenneth Sy, kennnethsy@gmail.com


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In a Nutshell

 Medication dosages can be ordered to be


weight.
This may require you to convert pounds to
kilograms or kilograms to pounds.

• There are 2.2 pounds (lbs) in each


kilogram (kg)

• To convert pounds to kilograms


divide the pounds by 2.2

• To convert kilograms to pounds


multiply the kilograms by 2.2

Kenneth Sy, kennnethsy@gmail.com


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In a Nutshell

 Nurses are responsible to ensure that any


ordered dose is within a safe and
therapeutic range for their patient.

 Always calculate the correct dosage as


indicated by the medication label and
compare the dosage with the dosage
ordered by the HCP.

 If the therapeutic range is not included on


the label consult with the pharmacist,
package insert, or PDR.

Kenneth Sy, kennnethsy@gmail.com


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This document is a property of: Kenneth Sy

Note: This document is copyright protected. It may not be copied, reproduced, used, or
distributed in any way without the written authorization of Lecturio GmbH.

Kenneth Sy, kennnethsy@gmail.com


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