Combined Model Question Papers From Unit 01 To 04 (Pharmacology-2) PDF

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“Solution-Pharmacy”
Pharmacology of Drugs Acting on CVS
Practice Question Paper (Unit-01)
B.Pharmacy- 5th Semester (New PCI Syllabus)
Note- All these questions are made by “Solution-Pharmacy” which are based on
our video lecture. Our objective for making these practice questions is to prepare
students for their examination. Total marks is- 75
Section 01- Multiple choice questions. (Attempt any 20 questions) 01marks each
1. Which of the following is/are properties of heart

(A) Automaticity
(B) Conductivity
(C) Rhythmicity
(D) All of the above
2. In “Congestive heart failure” what are the main disability of heart

(A) Force of contraction
(B) Over filling of blood in chamber
(C) Increase in Blood pressure
(D) Both A and B
3. In case of diastolic dysfunction of heart (In CHF) the ventricular wall become-
(A) Thick
(B) Thin
(C) No change
(D) Dead
4. Digoxin is mainly used in the treatment of following

(A) Hypertension
(B) Angina
(C) Arrhythmia
(D) CHF
5. What is the normal value of blood pressure (In mm/Hg)

(A) 120/80
(B) 80/120
(C) 120 Diastolic and 80 systolic
(D) 120 to 80
6. Which of the following disorder is generally considered as “Silent Killer”

(A) Hypertension
(B) Angina
(C) Arrhythmia
7. Which of the following is homoeostasis mechanism for hypertension

(A) Renin-Angiotensin- Aldosterone System
(B) Baroreceptor System
(C) Negative and Positive feedback mechanism

Page 1 of 4
8. Renin is secreted from

(A) Kidney
(B) Lungs
(C) Liver
(D) Stomach
9. Angiotensinogen is liberated from

(A) Lungs
(B) Kidney
(C) Stomach
(D) Pancreases
10. Nitric Oxide is

(A) Vasodilator
(B) Vasoconstrictor
(C) Both
(D) None
11. Angina is characterized by

(A) Left side chest pain
(B) Right Side chest pain
(C) Stomach pain
12. Which of the following is/are causes of angina

(A) Lack of oxygen supply
(B) Coronary artery spasm
(C) Both of the above
(D) Over production of oxygen
13. Angina pectoris is associated with

(A) Coronary artery
(B) Pulmonary artery
(C) Pulmonary Vein
14. Which of the following angina is also known as classical angina

(A) Effort induce
(B) Unstable
(C) Prinzmetal
(D) None of the above
15. For fast acting nitro-glycerine should be given by

(A) Oral
(B) Sublingual
(C) Buccal
(D) Intravenous
16. Which of the following is cause of arrhythmia

(A) Re-entry
(B) Unidirectional block
(C) Abnormal cardiac impulse generation
Page 2 of 4
17. Which of the following drug is an example of class IA antiarrhythmic drugs

(A) Quinidine
(B) Diclofenac
(C) Paracetamol
(D) Lidocaine
18. Which of the following is beneficial for CVS system

(A) LDL
(B) HDL
(C) VLDL
19. Which of the following is an example of direct renin inhibitor

(A) Aliskiren
(B) Captopril
(C) Enalapril
(D) Telmisartan
20. Re-Entry is a phenomenon of

(A) Arrhythmia
(B) Angina
(C) Hypertension
(D) Hyperlipidaemia
Extra Questions-
21. Which of the following is known as “Good- Cholesterol”

(A) LDL
(B) VLDL
(C) HDL
(D) Chylomicron
22. Which of the following has maximum risk for atherogenicity

(A) LDL
(B) HDL
(C) VLDL
(D) Chylomicron
23. HDL is responsible for

(A) Transport of lipid from liver to
peripheral tissue
(B) Transport of lipid from peripheral tissue to liver
(C) From intestine to liver
(D) From Liver to intestine
24. VLDL is synthesised in-

(A) Liver
(B) Intestine
(C) Stomach
(D) Pancreas
Page 3 of 4
25. Which of the following is causes of CHD

(A) Increase level of LDL and Triglyceride
(B) Increase level of HLD
(C) Decrease level of HDL
(D) Both A and C
Section- 02- Long Answer type questions. (Attempt any 02)- 20 Marks
1. Explain Hypertension. Classify the drugs used in the treatment of hypertension along
with the mechanism of action of ACE inhibitors in detail.
2. What do you understand by the angina? Give its type and drug used in treatment of
angina. Give complete pharmacology of nitro-glycerine.
3. Classify Antihyperlipidemic drugs. Explain the complete mechanism of action of HMG-
Co enzyme inhibitors
Section 03- Long answer type questions. (Attempt any 07)- 35 Marks
1. Explain electrophysiology of heart
2. Classify anti-Anginal drugs with suitable example
3. What is arrhythmia? Explain the re-entry phenomenon
4. Explain the mechanism of action of diuretic in the management of hypertension.
5. Explain the feedback mechanism in hypertension (RAS System)
6. Discuss the etiology of angina pectoris
7. Write the complete pharmacology of propranolol
8. Classify anti-arrhythmic drugs and explain MOA of Sodium channel blockers
9. Explain the formation of cholesterol formation.

Page 4 of 4
Pharmacology of Drugs Acting on CVS
Pharmacology of Drugs Acting on Urinary System
1. State of acute circulatory failure is known as-

(A) Shock
(B) Angina
(C) Hypertension
(D) Arrhythmia
2. Which of the following is cause/s for hypovolemic shock

(A) Haemorrhage
(B) Trauma
(C) Vomiting
3. Agents which are used to increase the formation of blood is called-

(A) Blood purifier
(B) Haematinics
(C) Fibrinolysis
(D) Erythropoiesis
4. Ionized Iron is not used, because-

(A) It may precipitate protein
(B) It may increase protein synthesis
(C) It is not able to provide haemoglobin
5. Which of the following type of vitamin K is synthesized by bacteria in gut

(A) Vitamin K1
(B) Vitamin K2
(C) Vitamin K3
(D) Vitamin K4
6. Which of the following is an example of oral anticoagulants

(A) Warfarin
(B) Dicumarol
(C) Rivaroxaban

Page 1 of 3
7. Which of the following was first anticoagulant
(A) Warfarin "Solution-Pharamcy" We believe in sharing not in selling
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(C) Dabigatran
(D) Hirudin
8. Heparin was extracted from

(A) Lungs
(B) Liver
(C) Kidney
(D) Brain
9. Heparin is safe in pregnancy because

(A) It may cross blood placental barrier
(B) It may not cross blood placental barrier
(C) It is synthesized from natural source
10. Streptokinase are obtained from-

(A) Beta- haemolytic streptococci
(B) Human urine
(C) Beta lactam bacteria
(D) From mold
11. Which of the following sentence is correct about Urokinase

(A) Prepared from Neonatal kidney
(B) Isolated from human urine
(C) It activate plasminogen and convert into- plasmin
12. Aspirin is an example of

(A) Coagulant
(B) Antihaemophilic drugs
(C) Antiplatelet drug
(D) All of the above "Solution-Pharamcy" We believe in sharing not in selling
13. What is the mechanism of action of aspirin

(A) Inhibition of prostaglandin synthesis
(B) Phosphodiaesterase Inhibitors
(C) ADP inhibitor
(D) Glycoprotein IIb and IIIa receptor antagonist
14. Which of the following is most effective diuretic

(A) Osmotic diuretic
(B) Thiazide diuretic
(C) Loop Diuretic
(D) Potassium Sparing Diuretic
15. Site of action of potassium sparing diuretic is-

(A) PCT
(B) DCT
(C) Collecting Duct
(D) Both B and C
Page 2 of 3
16. Which of the following agent is aldosterone antagonist

(A) Spironolactone
(B) Chlorthiazide
(C) Mannitol
17. Furosemide show diuretic effect at-

(A) Loop of Henle
(B) Proximal convoluted tubule
(C) Distal convoluted tubule
(D) Bowman capsule
18. Which of the following is an example of antidiuretic drug

(A) Vasopressin
(B) Desmopressin
(C) Terlipressin
19. Location of V1 receptor is

(A) Vascular smooth muscle
(B) Gut
(C) Urinary bladder
20. Which of the following is vasopressin antagonist

(A) Conivaptan
(B) Tolvaptan We have started
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(C) Both
(D) Carbamazepine
Section- 02- Long Answer type questions. (Attempt any 02)- 20 Marks
1. Define diuretic and classify them. Also give mechanism of action of loop diuretic with
its complete pharmacology.
2. Explain shock. Classify all drugs used in the treatment of shock
3. What are anticoagulants? Classify the anticoagulants with their mechanism of action of
any one drug.
Section 03- Short answer type questions. (Attempt any 07)- 35 Marks
1. Explain shock and its type

2. Define haematinics. Write their role in management of anaemia
3. Explain mechanism of action of warfarin
4. Explain the site of action of different diuretic
5. Write short note on antidiuretic
6. What do you understand by plasma volume expander
7. Classify antiplatelet drugs
8. What are coagulants? Explain the role of vitamin K
9. Explain the mechanism of action of osmotic diuretic

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Autacoids and related Drugs
Pharmacology of Drugs Acting on Urinary System
1. Agents which have limited activity on local area is termed as-

(A) Autacoids
(B) Hormones
(C) Enzymes
2. Histamine is released from

(A) Parietal cell
(B) Mast cell
(C) Goblet cell
3. Which of the following is location of non-mast cell histamine

(A) Brain
(B) Epidermis
(C) Gastric mucosa
4. Histamine effect on bronchial smooth muscle

(A) Contraction
(B) Relaxation
(C) No effect
(D) Contraction and then Relaxation
5. Histamine affect which receptor to stimulate gastric acid secretion

(A) H1
(B) H2
(C) H3
(D) H4
6. Which of the following drug does not produce drowsiness as compare to 1st generation
antihistaminic drugs
(A) Cetirizine
(B) Levo- Cetirizine
(C) Diphenhydramine
(D) Both A and B
Page 1 of 3
7. Which of the following is/are example of eicosanoid

(A) Prostaglandin
(B) Prostacyclin
(C) Thromboxane
8. Paracetamol generally affect which of the following type of COX

(A) COX-1
(B) COX-2
(C) COX-3
9. Angiotensinogen is synthesized in
(A) Liver
(B) Kidney
(C) Brain
(D) Heart
10. Substance P has following number of amino acids

(A) 10
(B) 11
(C) 12
(D) 13
11. NSAID drugs have following action

(A) Analgesic
(B) Anti-Pyretic
(C) Anti-Inflammatory
12. Which of the following is side effect of NSAID

(A) Gastric erosion
(B) Peptic ulcer
(C) Initiation of bleeding
13. Acetaminophen is also known as

(A) Paracetamol
(B) Aceclophanc
(C) Nimusulide
(D) Aspirin
14. The side effect of NSAID in most of the case is generally associated with
(A) Inhibition of COX-1
(B) Inhibition of COX-2
(C) Inhibition of COX-3
15. Gout is an example of

(A) Metabolic acidosis
(B) Metabolic disorder
(C) Genetic disorder
Page 2 of 3
16. The cause of gout is

(A) Over synthesis of uric acid
(B) Over synthesis of insulin
(C) Saturation of uric acid in blood
(D) Both A and C
17. Agent which increase elimination of uric acid via urine is called as
(A) Uricosouric agents
(B) Purine synthesis inhibitor
(C) Leukocyte inhibitor
(D) Antidiuretic
18. Colchicine MOA is

(A) Inhibition of Leukocyte migration
(B) Inhibition of Phagocytosis
(C) Inhibition of Xanthine oxidase
(D) Both A and B
19. Osteoarthritis is result of

(A) Physical work load
(B) Autoimmune disorder
(C) Genetic disorder
(D) Metabolic disorder
20. Rheumatic Arthritis cause is

(A) Autoimmune disorders
(B) Injury
(C) Genetics
Section 02- Long answer type questions. (Attempt any 2 questions)- 20 marks
1. Explain NSIAD. Classify the NSAID drugs and give mechanism of action of
paracetamol as antipyretic
2. Explain any 02 of the following- (1) Gout pathophysiology (2) Pathophysiology of
Arthritis (3) Antihistaminic drugs
3. Explain anti-gout drugs with its classification. Explain the MOA of colchicine in detail
Section 03- Short answer type questions (Attempt any 05 questions) – 35 Marks
1. Physiological role of histamine
2. Angiotensin receptor blockers
3. Bradykinin and substance P
4. Mechanism of action of allopurinol
5. Treatment of arthritis
6. Mechanism of action of aspirin as NSAID
7. Physiological importance of serotonin
8. Classification of autacoids
9. Antihistaminic drugs classification
Page 3 of 3

Pharmacology of Drugs Acting on Endocrine System
Note- All these questions are made by “Solution-Pharmacy” which are based
on our video lecture. Our objective for making these practice questions is to
prepare students for their examination. Total marks is- 75
1. A chemical which is being secreted by ductless gland is called

(A) Endocrine hormone
(B) Exocrine hormone
(C) Autacoids
2. The activity of circulatory control is regulated by

(A) Angiotensinogen
(B) Adrenaline
(C) Insulin
(D) Both A and B
3. Which of the following is responsible to convert the glycogen into glucose

(A) Insulin
(B) Glucagon
(C) Parathyroid
(D) Thyroid
4. Which of the following is considered as master endocrine gland

(A) Anterior pituitary
(B) Adenohypophysis "Solution-Pharamcy" We believe in sharing not in selling
(C) Both A and B
(D) Thyroid Gland
5. Secretion of Pituitary hormone is controlled by

(A) Hypothalamus
(B) Acidophil Cells
(C) Basophils Cells
6. Diabetes which can be manage or controlled by oral drugs is

(A) Type 1
(B) Type 2
(C) Both
(D) Insulin dependent diabetes
Page 1 of 3
7. Which of the following is or are causes of diabetes (Type 2)
(A) Down regulation of Insulin receptor
(B) Lack of insulin release
(C) Decrease sensitivity of cell for insulin
8. Excessive growth hormone may cause

(A) Gigantism in children
(B) Acromegaly in Adult
(C) Both
9. Which of the following hormones are secreted by thyroid

(A) Thyroxine
(B) Triiodothyronin "Solution-Pharamcy" We believe in sharing not in selling
(C) Calcitonin
10. Which of the following statement is true

(A) Thyroid secrete more T3 than T4
(B) Thyroid secrete more T4 than T3
(C) T4 is major circulating hormone
11. Adult hypothyroidism is also known as

(A) Myxoedema
(B) Nontoxic goiter
(C) Cretinism
(D) Thyroid Nodules
12. Goiter is
(A) Enlargnent of thyroid
(B) Shrinkage of thyroid
(C) Inhibition of Insulin release
13. Insulin was discovered by

(A) Banting and Best "Solution-Pharamcy" We believe in sharing not in selling
(B) Robert Hicochs We have started new youtube channel- "Pharamcy-Dictionary" Click to subscribe- https://www.youtube.com/channel/UCt6OXVV_2oxf5DD0Mad6e9A
(C) Pasture
(D) Rudolf Greatman
14. Glycogen synthesis is take place in liver by (Mostly)

(A) Insulin
(B) Glucagon
(C) Thyroid
(D) Both A and B
15. Lente insulin is mixture of

(A) Ultralente and Semilente in 7:3 ratio
(B) Ultralente and Semilente 3:7 ratio
(C) Ultralente and Semilente in 10: 05 ratio
Page 2 of 3
16. Which of the followings are analogues of insulin
(A) Insulin Aspart
(B) Insulin Glargine "Solution-Pharamcy" We believe in sharing not in selling
(C) Insulin Detemir
17. The 1st DPP-4 (Dipeptidyl peptidase-4) inhibitor is

(A) Sitagliptin
(B) Vildagliptin
(C) Saxagliptin
(D) Teneligliptin
18. The corticoids are –

(A) 20 carbon compound
(B) 21 carbon compound
(C) 22 carbon compound
(D) 19 carbon compound
19. Male sex hormones is

(A) Androgen
(B) Oestrogen "Solution-Pharamcy" We believe in sharing not in selling
(C) Progesterone
20. Which of the following is used in treatment of erectile dysfunction

(A) Sildenafil
(B) Flutamide
(C) Bicalutamide
(D) Raloxifene
Section 02- Long answer type questions. (Attempt any 2 questions)- 20 marks
1. Explain and classify Antidiabetic drugs. Give mechanism of action of sulfonylureas

2. Enumerated the list of anterior pituitary hormones and explain role of any one in
detail
3. Explain pharmacological action of thyroid hormone. Classify thyroid inhibitors and
explain radioactive iodine
Section 03- Short answer type questions (Attempt any 05 questions) – 35 Marks
1. Explain diabetes mellitus
2. Classify different hormones and their function in short
3. Write short note on anterior pituitary hormone
4. Explain the role of parathormone
5. Write short note son ACTH "Solution-Pharamcy" We believe in sharing not in selling
6. Explain sex hormones

7. Write short note son oral contraceptive agents
8. Explain the mechanism of action of alfa Glucosidase inhibitors
9. Write short note son glucocorticoid actions
Page 3 of 3

Combined Model Question Papers From Unit 01 To 04 (Pharmacology-2) PDF

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"Solution-Pharamcy" We believe in sharing not in selling

1. Which of the following is/are properties of heart

2. In “Congestive heart failure” what are the main disability of heart

4. Digoxin is mainly used in the treatment of following

5. What is the normal value of blood pressure (In mm/Hg)

6. Which of the following disorder is generally considered as “Silent Killer”

7. Which of the following is homoeostasis mechanism for hypertension

"Solution-Pharamcy" We believe in sharing not in selling

8. Renin is secreted from

9. Angiotensinogen is liberated from

10. Nitric Oxide is

11. Angina is characterized by

12. Which of the following is/are causes of angina

13. Angina pectoris is associated with

14. Which of the following angina is also known as classical angina

15. For fast acting nitro-glycerine should be given by

16. Which of the following is cause of arrhythmia

17. Which of the following drug is an example of class IA antiarrhythmic drugs

18. Which of the following is beneficial for CVS system

19. Which of the following is an example of direct renin inhibitor

20. Re-Entry is a phenomenon of

21. Which of the following is known as “Good- Cholesterol”

22. Which of the following has maximum risk for atherogenicity

23. HDL is responsible for

24. VLDL is synthesised in-

25. Which of the following is causes of CHD

"Solution-Pharamcy" We believe in sharing not in selling

1. State of acute circulatory failure is known as-

2. Which of the following is cause/s for hypovolemic shock

3. Agents which are used to increase the formation of blood is called-

4. Ionized Iron is not used, because-

5. Which of the following type of vitamin K is synthesized by bacteria in gut

6. Which of the following is an example of oral anticoagulants

"Solution-Pharamcy" We believe in sharing not in selling

8. Heparin was extracted from

9. Heparin is safe in pregnancy because

10. Streptokinase are obtained from-

11. Which of the following sentence is correct about Urokinase

12. Aspirin is an example of

13. What is the mechanism of action of aspirin

14. Which of the following is most effective diuretic

15. Site of action of potassium sparing diuretic is-

16. Which of the following agent is aldosterone antagonist

17. Furosemide show diuretic effect at-

18. Which of the following is an example of antidiuretic drug

19. Location of V1 receptor is

20. Which of the following is vasopressin antagonist

1. Explain shock and its type

"Solution-Pharamcy" We believe in sharing not in selling

1. Agents which have limited activity on local area is termed as-

2. Histamine is released from

3. Which of the following is location of non-mast cell histamine

4. Histamine effect on bronchial smooth muscle

5. Histamine affect which receptor to stimulate gastric acid secretion

7. Which of the following is/are example of eicosanoid

8. Paracetamol generally affect which of the following type of COX

10. Substance P has following number of amino acids

11. NSAID drugs have following action

12. Which of the following is side effect of NSAID

13. Acetaminophen is also known as

15. Gout is an example of

16. The cause of gout is

18. Colchicine MOA is