“Solution-Pharmacy”

Toxicology and Chronopharmacology

Practice Question Paper (Unit-05)
B.Pharmacy- 6th Semester (New PCI Syllabus)
Note- All these questions are made by “Solution-Pharmacy” which are based
on our video lecture. Our objective for making these practice questions is to
prepare students for their examination. Total marks is- 75
Section 01- Multiple choice questions. (Attempt any 20 questions) 01marks each

1. Agent which can cause cancer is called

(A) Carcinogenicity
(B) Carcinogen
(C) Mutagen
(D) Genotoxicity

2. Agent which is having ability to affect gene as toxic is considered as

(A) Mutagen
(B) Carcinogens
(C) Teratogens
(D) Genotoxic Agents

3. If any woman is pregnant and she has taken a drug which caused a fatal death it is called
(A) Teratogen
(B) Teratogenicity
(C) Mutagenicity
(D) Algeriogenicity

4. Full form of BAL is

(A) British anti-Lewisite
(B) British again-Lewisite
(C) British anti-Lewinide
(D) British antihistaminic-Lewisite

5. Universal antidote is
(A) BAL
(B) Dimercaprol
(C) Activated charcoal
(D) All of the above

6. Circadian rhythm is associated with (Most specific)

(A) 12 hours’ time frame
(B) 24 Hours’ Time frame
(C) Both A and B
(D) None of the above

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 7. EDTA is a
(A) Chelating agents
(B) Neutralizing agents
(C) Universal antidote s
(D) All of the above

8. Atropine is used in
(A) Organophosphate poisoning
(B) Lead poisoning
(C) Snake venom poisoning
(D) Arsenic poisoning

9. Organophosphate may cause toxicity by

(A) Accumulation of acetylcholine
(B) Accumulation of anticholinesterase
(C) Affecting neurotransmitter
(D) None of the above

10. MOA of activated charcoal is

(A) Adsorption
(B) Absorption
(C) Neutralization
(D) All of the above

11. Which of the following category is considered as safe during pregnancy

(A) Category A
(B) Category C
(C) Category X
(D) Category Z

12. Folic acid is an example of

(A) Category A
(B) Category B
(C) Category C
(D) Category X

13. Level of testosterone is at highest at

(A) Morning
(B) Afternoon
(C) Evening
(D) Night

14. Study of effect of time on ADME is called

(A) Chronopharmacodynamic
(B) Chronopharmacokinetic
(C) Chronobiology
(D) All of the above

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 15. Mutation may reflected in
(A) Transcription
(B) Translation
(C) Replication
(D) All of the above

16. If the base is changed but the result is the same then it is an example of
(A) Silent mutation
(B) Missense mutation
(C) Nonsense mutation
(D) None of the above

17. Methanol poisoning can be treated by

(A) Ethanol
(B) Methanol itself
(C) Butanol
(D) Any of the alcohol

18. Emetics are not to be used in case of

(A) Corrosive poisoning
(B) Non supportive patient
(C) Unconscious patient
(D) All of the above

19. Opioid toxicity can be treated by

(A) Naloxone
(B) Activated charcoal
(C) Emetics
(D) None of the above

20. Example of organophosphate poison

(A) Melathion
(B) Parathion
(C) Tabun
(D) All of the above

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 Section 02- Long answer type questions (Attempt ay 02 questions) 10X2=20 marks

1. Explain the poisoning and give detail account on different method of treatment of
poisoning with advantages and limitations
2. Explain Chronopharmacology and give its application

Section 03- Short answer types questions (Attempt any 07) 05X7=35

1. Explain mechanism of action of activated charcoal

2. Write short note on opioid poisoning and its antidotes
3. Define the term teratogenicity and mutagenicity with example
4. White a note on organophosphate poisoning
5. Explain heavy metal poisoning with treatment approaches
6. What is EDTA
7. Define Genotoxic drugs and carcinogens
8. Explain mutation with its types
9. What is circadian rhythm and what is its role

Answer Keys –

Question Answer Question Answer

01 B 11 A
02 D 12 A
03 A 13 A
04 A 14 B
05 C 15 D
06 B 16 A
07 A 17 A
08 A 18 D
09 A 19 A
10 A 20 D

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